Biological sampling device

By setting a flexible water-absorbing structure to adsorb the preservative in the sampling tube, the problem of inactivation of biological samples during transportation is solved, and stable storage and convenient transportation of samples are achieved.

CN223481140UActive Publication Date: 2025-10-28SHENZHEN LIAOSHIYUAN BIOMEDICAL TECH CO LTD
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Patent Information

Application Number
CN202422870088.4
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-11-22
Publication Date
2025-10-28
Estimated Expiration
2034-11-22

AI Technical Summary

Technical Problem

In biological DNA testing, collected biological samples are easily inactivated during long-term transportation, and existing technologies make it difficult to effectively protect samples and ensure transportation stability.

Method used

A flexible water-absorbing structure is set in the sampling tube to absorb the biological sample preservative. After the sampling cotton head contacts the flexible water-absorbing structure, the sample survival time is extended, and the friction between the flexible water-absorbing structure and the inner wall of the test tube is used to fix the sample to ensure stable contact.

Benefits of technology

It prolongs the survival time of biological samples, reduces transportation requirements, prevents leakage of preservatives, and improves transportation convenience and sample stability.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model provides a biological sampling device which comprises a sampling test tube and a sampling swab, one end of the sampling test tube is provided with an opening, the inner side of the other end of the sampling test tube is provided with a flexible water absorption structure, and a biological sample preservative is adsorbed in the flexible water absorption structure; the sampling swab comprises a sampling rod, a sampling cotton head and a sampling sealing cover, the sampling cotton head is arranged at one end of the sampling rod, the sampling sealing cover is arranged at the other end of the sampling rod, the sampling cotton head is in contact with the flexible water absorption structure, and the sampling sealing cover is connected to an opening of the sampling test tube. The biological sample preservative in the flexible water absorption structure can prolong the survival time of the biological sample, and the flexible water absorption structure is always in contact with the sampling cotton head of the biological sample preservative no matter which posture the sampling test tube is in, so that the transportation requirement of the sampling test tube is reduced, the transportation is more convenient, and the leakage of the biological sample preservative can be effectively prevented.
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Description

Technical Field

[0001] This utility model belongs to the field of medical devices, and in particular relates to a biological sampling device. Background Technology

[0002] In the process of biological DNA detection and analysis, it is usually necessary to collect live biological samples, such as by collecting exfoliated cells from the oral mucosa or cervix. Because this method is non-invasive, painless, and easy to operate, it has gradually been widely used.

[0003] After taking throat swabs or other samples, the swabs need to be placed in test tubes for preservation and then the test tubes are sent to the laboratory for testing. However, in actual sampling work, long hours are often required, but the collected swabs need to be sent for testing in a timely manner to avoid biological sample inactivation and test failure.

[0004] Chinese utility model patent CN204698816U discloses a suction-type oral swab sampling device. The sampling swab includes a protective sleeve with a clamp on the top side wall of the protective sleeve. The clamp holds the swab carrier, and the swab carrier is connected to a piercing rod that extends inside the protective sleeve. A push rod is slidably disposed inside the protective sleeve, with one end of the push rod abutting against the piercing rod and the other end extending out of the protective sleeve. The sample storage tube includes a tube body and a tube cap. The top of the tube cap has a space for storing a biological sample preservative, and the bottom of the space has a sealing membrane. When the tube cap is tightened, the tip of the piercing rod punctures the sealing membrane, and the preservative flows along the piercing rod to the swab carrier for full absorption. This facilitates storage and air transport, thereby shortening mailing time.

[0005] However, during actual transportation, test tubes must be secured with a rack to prevent them from tipping over. Otherwise, once tipped over, the preservative inside the test tube will no longer be able to protect the biological sample on the swab, thus losing its long-term storage effect. Utility Model Content

[0006] The technical objective of this invention is to provide a biological sampling device that aims to improve the survival time of biological samples and make transportation more convenient.

[0007] To solve the above-mentioned technical problems, this utility model is implemented as follows: a biological sampling device includes a sampling tube and a sampling swab. One end of the sampling tube has an opening, and the other end of the sampling tube has a flexible water-absorbing structure on its inner side, in which a biological sample preservative is adsorbed.

[0008] The sampling swab includes a sampling rod, a sampling cotton head, and a sampling sealing cap. The sampling cotton head is located at one end of the sampling rod, and the sampling sealing cap is located at the other end of the sampling rod. The sampling cotton head is in contact with the flexible absorbent structure, and the sampling sealing cap is connected to the opening of the sampling tube.

[0009] Furthermore, a groove is provided in the middle of the flexible absorbent structure, and the sampling cotton head is disposed in the groove.

[0010] Furthermore, the shape of the groove is the same as that of the sampling cotton head.

[0011] Furthermore, the flexible absorbent structure is a gel or a sponge.

[0012] Furthermore, a sealing structure is connected to the opening at one end of the sampling tube. After sampling, the sealing structure is removed, and after the sampling swab is placed into the sampling tube, the sampling sealing cap is connected to the opening of the sampling tube.

[0013] Furthermore, the sampling sealing cap is threaded or interference-fitted at the opening of the sampling tube.

[0014] Furthermore, the sealing structure is a test tube sealing cap, which is threaded or interference-fitted to the opening of the sampling test tube.

[0015] Furthermore, the sampling tube is also equipped with a water-proof baffle, which is located on the side of the flexible absorbent structure near the opening of the sampling tube. The water-proof baffle is made of elastic material, and a central hole is provided in the middle of the water-proof baffle for the sampling cotton head to pass through.

[0016] Furthermore, the sampling rod is also provided with an auxiliary cotton head, which is disposed between the sampling cotton head and the sampling sealing cap. The diameter of the auxiliary cotton head is larger than the diameter of the sampling cotton head, and the diameter of the auxiliary cotton head is smaller than the diameter of the central hole.

[0017] Furthermore, the water-proof baffle is made of silicone, and absorbent cotton is provided on at least one side of the water-proof baffle.

[0018] Furthermore, it also includes an intermediate tube, the lower end of which is connected to the opening of the sampling test tube, the lower end of the sampling sealing cap is connected to the intermediate tube, the sampling rod is disposed through the intermediate tube, and the lower end of the intermediate tube has the same size as the lower end of the sampling sealing cap.

[0019] Furthermore, the sampling tube is made of a soft material, which is not afraid of being squeezed or dropped, and is crack-proof, leak-proof, and convenient for transportation.

[0020] Compared with the prior art, the biological sampling device of this invention has the following advantages:

[0021] This invention relates to a biological sampling device that incorporates a flexible absorbent structure inside the sampling tube. This structure contains a biological sample preservative. After sampling, the sampling cotton head is inserted into the sampling tube and comes into contact with the flexible absorbent structure. This allows the biological sample preservative within the flexible absorbent structure to extend the survival time of the biological sample. Furthermore, once the flexible absorbent structure is fixed inside the sampling tube, its flexibility and the friction between it and the inner wall of the tube ensure reliable fixation. This ensures that regardless of the sampling tube's orientation, the flexible absorbent structure remains in contact with the biological sample preservative sampling cotton head, reducing transportation requirements and making transportation more convenient. It also effectively prevents leakage of the biological sample preservative. Attached Figure Description

[0022] Figure 1 This is a schematic diagram of the sampling test tube in Embodiment 1 of this utility model;

[0023] Figure 2 This is a schematic diagram of the sampling swab in Embodiment 1 of this utility model;

[0024] Figure 3 This is a schematic diagram of the structure of the sampling swab fixed inside the sampling tube in Embodiment 1 of this utility model;

[0025] Figure 4 This is a schematic diagram of the sampling test tube in Embodiment 2 of this utility model;

[0026] Figure 5 This is a schematic diagram of the structure of the sampling swab fixed inside the sampling tube in Embodiment 2 of this utility model;

[0027] Figure 6 This is a schematic diagram of the sampling test tube in Embodiment 3 of this utility model;

[0028] Figure 7 This is a schematic diagram of the sampling swab in Embodiment 3 of this utility model;

[0029] Figure 8 This is a schematic diagram of the structure of the sampling swab fixed inside the sampling tube in Embodiment 3 of this utility model;

[0030] Figure 9 This is a schematic diagram of the biological sampling device in Embodiment 4 of this utility model;

[0031] Figure 10 This is an exploded view of the biological sampling device in Embodiment 4 of this utility model;

[0032] Figure 11This is a schematic diagram of the biological sampling device after sampling in Embodiment 4 of this utility model.

[0033] In the accompanying drawings, the reference numerals indicate:

[0034] 1-Sampling tube 2-Test tube sealing cap 3-Flexible absorbent structure 4-Sampling rod 5-Sampling cotton head 6-Sampling sealing cap 7-Groove 8-Water-proof baffle 9-Central hole 10-Auxiliary cotton head 11-Intermediate tube. Detailed Implementation

[0035] The embodiments of this utility model are described in detail below. Examples of these embodiments are shown in the accompanying drawings, wherein the same or similar reference numerals denote the same or similar elements or elements having the same or similar functions throughout. The embodiments described below with reference to the accompanying drawings are exemplary and intended to explain this utility model, and should not be construed as limiting this utility model. All other embodiments obtained by those skilled in the art based on the embodiments of this utility model without inventive effort are within the scope of protection of this utility model.

[0036] In the description of this utility model, it should be understood that the terms "center", "longitudinal", "transverse", "length", "width", "thickness", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise", "axial", "circumferential", "radial", etc., indicating the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings, are only for the convenience of describing this utility model and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of this utility model.

[0037] Furthermore, the terms "first" and "second" are used for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of that feature. In the description of this utility model, "a plurality of" means two or more, unless otherwise explicitly specified.

[0038] Example 1:

[0039] See Figure 1-2In this embodiment, the biological sampling device includes a sampling tube 1 and a sampling swab. One end of the sampling tube 1 has an opening, and the other end of the sampling tube 1 has a flexible absorbent structure 3 inside, within which a biological sample preservative is adsorbed. A sealing structure is connected to the opening at one end of the sampling tube 1; specifically, the sealing structure is a tube sealing cap 2, which is threaded onto the opening of the sampling tube 1. The sampling tube 1 is made of a soft material, is resistant to compression and drops, is crack-proof, leak-proof, and convenient for transportation.

[0040] The sampling swab includes a sampling rod 4, a sampling cotton head 5, and a sampling sealing cap 6. The sampling cotton head 5 is located at one end of the sampling rod 4, and the sampling sealing cap 6 is located at the other end of the sampling rod 4. The sampling cotton head 5 is in contact with the flexible absorbent structure 3, and the sampling sealing cap 6 is threadedly connected to the opening of the sampling test tube 1. After sampling, the test tube sealing cap 2 is removed, and the sampling sealing cap 6 is connected to the opening of the sampling test tube 1.

[0041] In this embodiment, the flexible absorbent structure 3 is a gel or sponge. After the flexible absorbent structure 3 is fixed inside the sampling tube 1, due to its own flexibility, the friction between the flexible absorbent structure 3 and the inner wall of the sampling tube 1 will reliably fix the flexible absorbent structure 3 inside the sampling tube 1. Thus, no matter what position the sampling tube 1 is in, the flexible absorbent structure 3 will always be in contact with the sampling cotton head 5 of the biological sample preservation agent, reducing the transportation requirements of the sampling tube 1 and making transportation more convenient.

[0042] See Figure 3 When using the sampler, remove the sampling swab from the sealed bag, use the sampling cotton head 5 to scrape the area to be sampled, remove the test tube sealing cap 2 from the sampling tube 1, then insert the sampling rod 4 into the sampling tube 1, connect the sampling tube 1 through the sampling sealing cap 6 and make the sampling cotton head 5 contact the flexible absorbent structure 3. The biological sample preservative adsorbed in the flexible absorbent structure 3 can extend the survival time of the biological sample on the sampling cotton head 5. The flexible absorbent structure 3 is always in contact with the biological sample preservative sampling cotton head 5, which reduces the transportation requirements of the sampling tube 1, makes transportation more convenient, and can effectively prevent leakage of the biological sample preservative.

[0043] In this embodiment, the test tube sealing cap 2 and the sampling sealing cap 6 can also be made of elastic material and are interlocked with the opening of the sampling test tube 1, making the connection convenient and providing excellent sealing. Of course, the test tube sealing cap 2 and the sampling sealing cap 6 can also be connected to the sampling test tube 1 using other sealing methods.

[0044] Example 2:

[0045] See Figure 4-5In this embodiment, a groove 7 is provided in the middle of the flexible absorbent structure 3, and the sampling cotton head 5 is placed in the groove 7, so that the sampling cotton head 5 can be wrapped in the groove 7 of the flexible absorbent structure 3, thereby further extending the activity time of the biological sample.

[0046] Furthermore, in this embodiment, the groove 7 has the same shape as the sampling cotton head 5. The groove 7 matches the sampling cotton head 5, providing better coverage, longer retention time, and more comprehensive protection.

[0047] Example 3:

[0048] See Figure 6 In this embodiment, a water-proof baffle 8 is also provided inside the sampling tube 1. The water-proof baffle 8 is located on the side of the flexible absorbent structure 3 near the opening of the sampling tube 1. The water-proof baffle 8 is made of elastic material, and a central hole 9 is provided in the middle of the water-proof baffle 8 for the sampling cotton head 5 to pass through. The diameter of the sampling cotton head 5 is smaller than the diameter of the central hole 9. After the sampling cotton head 5 comes into contact with the flexible absorbent structure 3, it may exert some pressure on the flexible absorbent structure 3. Especially when the sampling tube 1 is tilted, the biological sample preservative may be squeezed out of the flexible absorbent structure 3. At this time, the water-proof baffle 8 can form a certain obstruction for the biological sample preservative.

[0049] The water-proof baffle 8 is made of silicone. At least one side of the water-proof baffle 8 is also provided with absorbent cotton. There is a certain gap between the water-proof baffle 8 and the flexible absorbent structure 3. Under normal circumstances, the absorbent cotton does not work. Once the biological sample preservative is squeezed out, the absorbent cotton can absorb this part of the biological sample preservative, preventing the biological sample preservative from flowing to the opening of the sampling tube 1.

[0050] See Figure 7-8 Furthermore, the sampling rod 4 is also equipped with an auxiliary cotton head 10, which is positioned between the sampling cotton head 5 and the sampling sealing cap 6. The diameter of the auxiliary cotton head 10 is larger than that of the sampling cotton head 5, and smaller than that of the central hole 9. After the sampling cotton head 5 passes through the central hole 9, the auxiliary cotton head 10 contacts and drives the water-blocking baffle 8 to move towards the flexible water-absorbing structure 3 to achieve a better water-blocking effect.

[0051] Example 4:

[0052] See Figure 9-10The biological sampling device in this embodiment also includes an intermediate tube 11. The lower end of the intermediate tube 11 is threaded to the opening of the sampling tube 1. The lower end of the sampling sealing cap 6 is threaded to the intermediate tube 11. The sampling rod 4 passes through the intermediate tube 11. The thread at the lower end of the intermediate tube 11 has the same thread size as the thread at the lower end of the sampling sealing cap 6. Due to the elongated structure of the intermediate tube 11, the sampling cotton head 5 is moved away from the flexible absorbent structure 3. Before sampling, the sampling swab is connected to the sampling tube 1, eliminating the need for separate sealing of the sampling swab, thus simplifying the structure.

[0053] See Figure 11 After sampling is completed, the intermediate tube 11 is removed from the sampling tube 1. The intermediate tube 11 is discarded or disinfected and reused. The sampling rod 4 inserts the sampling cotton head 5 into the flexible absorbent structure 3 and threads the sampling sealing cap 6 to the opening of the sampling tube 1.

[0054] In this embodiment, the intermediate tube 11 and the sampling sealing cap 6 can also be made of elastic material and are interlocked with the opening of the sampling tube 1, which is convenient to connect and has good sealing performance. Of course, the intermediate tube 11 and the sampling sealing cap 6 can also be connected to the sampling tube 1 using other sealing methods.

[0055] The above are only preferred embodiments of the present invention and are not intended to limit the present invention. Any modifications, equivalent replacements and improvements made within the spirit and principles of the present invention should be included in the scope of protection of the present invention.

Claims

1. A biological sampling device, characterized in that, It includes a sampling tube and a sampling swab. One end of the sampling tube has an opening, and the other end of the sampling tube has a flexible water-absorbing structure inside, in which a biological sample preservative is adsorbed. The sampling swab includes a sampling rod, a sampling cotton head, and a sampling sealing cap. The sampling cotton head is located at one end of the sampling rod, and the sampling sealing cap is located at the other end of the sampling rod. The sampling cotton head is in contact with the flexible absorbent structure, and the sampling sealing cap is connected to the opening of the sampling tube.

2. The biological sampling device according to claim 1, characterized in that, The flexible absorbent structure has a groove in the middle, and the sampling cotton head is placed in the groove.

3. The biological sampling device according to claim 2, characterized in that, The shape of the groove is the same as that of the sampling cotton head.

4. The biological sampling device according to claim 1 or 2, characterized in that, The flexible absorbent structure is a gel or a sponge.

5. The biological sampling device according to claim 1, characterized in that, The sampling tube has a sealing structure at one end of its opening. After sampling, the sealing structure is removed, the sampling swab is placed into the sampling tube, and the sampling sealing cap is then connected to the opening of the sampling tube.

6. The biological sampling device according to claim 5, characterized in that, The sealing structure is a test tube sealing cap, which is threaded or interference-fitted to the opening of the sampling test tube.

7. The biological sampling device according to claim 1, characterized in that, The sampling tube is also equipped with a water-proof baffle. The water-proof baffle is located on the side of the flexible water-absorbing structure near the opening of the sampling tube. The water-proof baffle is made of elastic material, and a central hole is opened in the middle of the water-proof baffle for the sampling cotton head to pass through.

8. The biological sampling device according to claim 7, characterized in that, The sampling rod is also provided with an auxiliary cotton head, which is located between the sampling cotton head and the sampling sealing cap. The diameter of the auxiliary cotton head is larger than that of the sampling cotton head, and the diameter of the auxiliary cotton head is smaller than that of the central hole.

9. The biological sampling device according to claim 7, characterized in that, The water-proof baffle is made of silicone, and absorbent cotton is provided on at least one side of the water-proof baffle.

10. The biological sampling device according to claim 1, characterized in that, It also includes an intermediate tube, the lower end of which is connected to the opening of the sampling test tube, the lower end of the sampling sealing cap is connected to the intermediate tube, the sampling rod is disposed through the intermediate tube, and the lower end of the intermediate tube has the same size as the lower end of the sampling sealing cap.

Citation Information

Patent Citations

  • Blot formula oral cavity swab sampling device

    CN204698816U