Full-automatic biological tissue section dyeing device

Abstract

The utility model relates to the technical field of biological detection equipment, in particular to a full-automatic biological tissue section dyeing device which comprises a machine box and a control box, a tray and an XYZ mechanical arm are arranged in the machine box, the tray is connected with an oscillation mechanism, the oscillation mechanism comprises a rack and an oscillation assembly, and the oscillation assembly comprises a fixing frame, a fluted disc assembly and a motor assembly. The fluted disc assembly comprises a sector gear, a connecting rod is fixedly connected to a center shaft of the sector gear, the center shaft of the sector gear is hinged to the fixing frame, a sliding rod is arranged at the tail end of the connecting rod, the motor assembly comprises a rotating motor and a transmission assembly, the transmission assembly is a cylindrical transmission shaft, a wavy groove is formed in the transmission shaft, and the sliding rod slides along the groove. The utility model has the beneficial effects that the tray can be shaken left and right, so that the reagent in the reagent cylinder is shaken, the flowing of the reagent is accelerated, the dyeing is accelerated, the dyeing is more uniform, the dyeing time is shortened, and the dyeing efficiency is improved.

Description

Technical Field

[0001] This utility model relates to the field of biological detection equipment technology, specifically to a fully automated biological tissue section staining device. Background Technology

[0002] A biological tissue staining machine is an experimental device used for staining biological tissue or cell samples. Its main function is to apply the principles of chemical staining, adding cell staining agents or antibodies to treat tissue or cell samples for diagnostic, research, or training purposes. Its main advantage is the ability to quickly and accurately stain large quantities of tissue or cell samples. Its applications are wide-ranging, including physiology, pathology, biology, medicine, and pharmacology. It has extensive applications in drug research, clinical diagnosis, and biomedical research. Existing staining devices typically use a robotic arm to hold the slides, which moves up and down linearly within reagent tanks, repeatedly immersing them to complete steps such as dewaxing, washing, inversion, and rinsing. This process is time-consuming, especially wasting time within the reagent tanks, resulting in low staining efficiency. Therefore, there is a need to develop new staining machines to shorten staining time and improve staining efficiency. Utility Model Content

[0003] To address the problems existing in the prior art, this utility model provides a fully automated biological tissue section staining device to solve the problems of long staining time and low staining efficiency.

[0004] To solve the above problems, the technical solution of this utility model is as follows: A fully automatic biological tissue section staining device includes a chassis and a control box. A tray for placing reagent cylinders is provided inside the chassis. An XYZ manipulator for hanging glass slides is provided above the tray. The tray is connected to an oscillation mechanism that oscillates the tray left and right, which is located in the control box.

[0005] Furthermore, the oscillation mechanism includes a rack connected to one side of the tray, and the rack is connected to an oscillation component.

[0006] Furthermore, the oscillation assembly includes a fixed frame disposed within a control box, the fixed frame being connected to a geared disc assembly, and the geared disc assembly being connected to a motor assembly.

[0007] Furthermore, the gear assembly includes a sector gear that meshes with the rack, a connecting rod is fixedly connected to the central axis of the sector gear, the central axis of the sector gear is hinged to the fixed frame, and a sliding rod is provided at the end of the connecting rod.

[0008] Furthermore, the motor assembly includes a rotary motor, and the output end of the rotary motor is connected to a transmission assembly that is slidably connected to the sliding rod.

[0009] Furthermore, the transmission component is a cylindrical transmission shaft with a wavy groove on it, and the sliding rod slides along the groove.

[0010] Furthermore, a groove is provided at the bottom of the tray, and a slide rail adapted to the groove is provided at the bottom of the chassis.

[0011] Furthermore, a speed reducer is provided between the rotary motor and the drive shaft.

[0012] Furthermore, the XYZ robotic arm includes an X-axis robotic arm, a Y-axis robotic arm, and a Z-axis robotic arm. An X-axis guide rail is provided inside the housing for the X-axis robotic arm to slide on. A Z-axis guide rail is provided on the X-axis robotic arm, and a Y-axis guide rail is provided on the Z-axis robotic arm. The X-axis robotic arm, Y-axis robotic arm, and Z-axis robotic arm are respectively connected to a conveyor belt and a drive motor. The Y-axis robotic arm is connected to a hook for suspending the glass frame.

[0013] Furthermore, a ventilation and heating mechanism is installed inside the chassis.

[0014] Compared with the prior art, the present invention has the following advantages: the oscillation mechanism can shake the tray left and right, causing the reagent in the reagent cylinder to shake, accelerating the flow of the reagent, speeding up the staining, and making the staining more uniform, shortening the staining time and improving the staining efficiency. Attached Figure Description

[0015] Figure 1 This is a schematic diagram of the structure of this utility model;

[0016] Figure 2 This is a schematic diagram of the oscillation mechanism of this utility model;

[0017] Figure 3 This is a schematic diagram of the glass carrier structure of this utility model.

[0018] In the diagram: 1. Chassis, 2. Control box, 3. Reagent cylinder, 4. Tray, 401 slide, 5. Glass holder, 6. Rack, 7. Fixture, 8. Sector gear, 9. Connecting rod, 10. Sliding rod, 11. Rotary motor, 12. Drive shaft, 1201 groove, 13. X-axis robotic arm, 14. Y-axis robotic arm, 15. Z-axis robotic arm, 16. X-axis guide rail, 17. Hook. Detailed Implementation

[0019] like Figure 1 , Figure 2 , Figure 3 As shown, a fully automated biological tissue section staining device includes a chassis 1 and a control box 2. The chassis 1 is provided with a tray 4 for placing reagent cylinders 3. Above the tray 4 is an XYZ manipulator for hanging glass slides 5. The tray 4 is connected to a oscillation mechanism located in the control box 2 that oscillates the tray 4 left and right. The chassis 1 is provided with a ventilation and heating mechanism to accelerate the drying of stained slides.

[0020] like Figure 2 As shown, the oscillation mechanism includes a rack 6 connected to one side of the tray 4. The rack 6 is connected to an oscillation assembly. The oscillation assembly includes a fixed frame 7 located inside the control box 2. The fixed frame 7 is connected to a gear plate assembly. The gear plate assembly is connected to a motor assembly. The gear plate assembly includes a sector gear 8 that meshes with the rack 6. A connecting rod 9 is fixedly connected to the central shaft of the sector gear 8. The central shaft of the sector gear 8 is hinged to the fixed frame 7. A sliding rod 10 is provided at the end of the connecting rod 9. The motor assembly includes a rotary motor 11. The output end of the rotary motor 11 is connected to a transmission assembly that is slidably connected to the sliding rod 10. The transmission assembly is a cylindrical transmission shaft 12. A wave-shaped groove 1201 is provided on the transmission shaft 12. The sliding rod 10 slides along the groove 1201. A slide groove 401 is provided at the bottom of the tray 4. A slide rail adapted to the slide groove 401 is provided at the bottom of the housing 1 (not shown in the figure). A reducer is provided between the rotary motor 11 and the transmission shaft 12.

[0021] The XYZ robotic arm includes an X-axis robotic arm 13, a Y-axis robotic arm 14, and a Z-axis robotic arm 15. An X-axis guide rail 16 is provided inside the housing 1 for the X-axis robotic arm 13 to slide on. A Z-axis guide rail is provided on the X-axis robotic arm 13, and a Y-axis guide rail is provided on the Z-axis robotic arm 15. The X-axis robotic arm 13, Y-axis robotic arm 14, and Z-axis robotic arm 15 are respectively connected to a conveyor belt and a drive motor. The XYZ robotic arm is existing technology and will not be described in detail further. Its specific structural diagram is not shown in the figure. The Y-axis robotic arm 14 is connected to a hook 17 for suspending the glass frame 5.

[0022] In use, through the coordinated work of three robotic arms, the hook 17 of the robotic arm can grasp the glass holder 5 and move it up and down in the reagent cylinder 3, immersing it in the staining agent; at the same time, the rotary motor 11 rotates, driving the transmission shaft 12 to rotate, the sliding rod 10 slides along the groove 1201 on the transmission shaft 12, the sector gear 8 meshes with the rack 6 and sways left and right with the wave-shaped groove 1201, the tray 4 oscillates left and right, completing the up and down movement of the glass holder 5, and synchronously oscillating the reagent cylinder 3 left and right, improving the uniformity of staining, shortening the staining time, and improving the staining efficiency.

[0023] The above specific embodiments are only used to illustrate the technical solution of this utility model and are not intended to limit it. Although this utility model has been described in detail with reference to examples, those skilled in the art should understand that modifications or equivalent substitutions can be made to the technical solution of this utility model without departing from the scope of the technical solution of this utility model, and all such modifications or substitutions should be covered within the scope of the claims of this utility model.

Claims

1. A fully automated biological tissue section staining device, comprising a chassis and a control box, characterized in that: The machine housing contains a tray for holding reagent cylinders, and above the tray is an XYZ robotic arm for hanging glass slides. The tray is connected to a oscillation mechanism located in the control box that oscillates the tray left and right.

2. The fully automated biological tissue section staining device according to claim 1, characterized in that: The oscillation mechanism includes a rack connected to one side of the tray, and the rack is connected to an oscillation component.

3. The fully automated biological tissue section staining device according to claim 2, characterized in that: The oscillation assembly includes a fixed frame located inside a control box, the fixed frame being connected to a geared disc assembly, and the geared disc assembly being connected to a motor assembly.

4. The fully automated biological tissue section staining device according to claim 3, characterized in that: The gear assembly includes a sector gear that meshes with a rack. A connecting rod is fixedly connected to the central axis of the sector gear. The central axis of the sector gear is hinged to a fixed frame. A sliding rod is provided at the end of the connecting rod.

5. The fully automated biological tissue section staining device according to claim 4, characterized in that: The motor assembly includes a rotary motor, and the output end of the rotary motor is connected to a transmission assembly that is slidably connected to the sliding rod.

6. The fully automated biological tissue section staining device according to claim 5, characterized in that: The transmission component is a cylindrical transmission shaft with a wavy groove on it, and the sliding rod slides along the groove.

7. The fully automated biological tissue section staining device according to claim 6, characterized in that: The bottom of the tray has a groove, and the bottom of the chassis has a slide rail that matches the groove.

8. The fully automated biological tissue section staining device according to claim 7, characterized in that: A speed reducer is installed between the rotary motor and the drive shaft.

9. The fully automated biological tissue section staining device according to claim 1, characterized in that: The XYZ robotic arm includes an X-axis robotic arm, a Y-axis robotic arm, and a Z-axis robotic arm. An X-axis guide rail is provided inside the housing for the X-axis robotic arm to slide on. A Z-axis guide rail is provided on the X-axis robotic arm, and a Y-axis guide rail is provided on the Z-axis robotic arm. The X-axis robotic arm, Y-axis robotic arm, and Z-axis robotic arm are respectively connected to a conveyor belt and a drive motor. The Y-axis robotic arm is connected to a hook for suspending the glass frame.

10. The fully automated biological tissue section staining device according to claim 1, characterized in that: The chassis is equipped with a ventilation and heating mechanism.

Images