SnoRNA typing diagnosis and detection kit

Abstract

The utility model provides a SnoRNA typing diagnosis and detection kit which comprises a kit body, symmetrically distributed hinges arranged on the rear side of the kit body, a kit cover rotationally arranged between the hinges, a first connecting block arranged in the middle of the kit cover, a second connecting block arranged in the middle of the kit body, symmetrically distributed rotating plates rotationally arranged on the front side of the kit body, and a third connecting block arranged between the rotating plates. A buckle cover is rotationally arranged between the two rotating plates, the first connecting block and the second connecting block are both installed with the buckle cover in a matched mode, a support is arranged in the box body, fixing holes which are symmetrically distributed are formed in the upper surface of the support, a rubber plate is arranged at the bottom end in the box body, and placing tables and clamping and fixing modules which are evenly distributed are arranged on the upper surface of the rubber plate. According to the SnoRNA typing diagnosis and detection kit disclosed by the utility model, different models can be quickly and firmly fixed when the detection test tubes in the kit body need to be replaced, so that the kit is convenient for personnel to use.

Description

TECHNICAL FIELD

[0001] The utility model belongs to the field of biotechnology, especially relates to a SnoRNA typing diagnosis, detection kit. BACKGROUND

[0002] SnoRNA (small nucleolar RNA) plays an important role in cells, especially in the modification and processing of rRNA. In recent years, with the in-depth study of the biological function of SnoRNA and its role in diseases, SnoRNA as a potential biomarker shows increasing potential in disease diagnosis, typing and prognosis evaluation. Therefore, the SnoRNA detection and typing kit is particularly important in disease diagnosis and typing.

[0003] The existing typing diagnosis and detection kit is composed of a box body, a rack and test tubes. During typing diagnosis and detection, real-time fluorescent quantitative PCR is used to make the test tubes react, and typing diagnosis and detection are realized by monitoring the test tube reaction in the kit. However, the test tubes for monitoring are inserted into the fixed holes on the rack to fix the test tubes. However, since the diameters of test tubes are different, personnel need to remove the rack from the inside of the box body and replace it with a rack with appropriate fixed holes when different types of test tubes are needed for typing diagnosis and detection. This process takes time and increases the workload of typing diagnosis and detection, which is not conducive to personnel use. UTILITY MODEL CONTENTS

[0004] Therefore, the utility model provides a SnoRNA typing diagnosis and detection kit to quickly and firmly fix different types of test tubes when the test tubes inside the box body need to be replaced, which is convenient for personnel use.

[0005] To solve the above technical problems, the utility model adopts the technical scheme of a SnoRNA typing diagnosis and detection kit, which comprises a box body, symmetrical hinges arranged on the rear side of the box body, a box cover rotatably arranged between the hinges, a connecting block one arranged in the middle of the box cover, a connecting block two arranged in the middle of the box body, symmetrical rotating plates rotatably arranged on the front side of the box body, a buckle cover rotatably arranged between the two rotating plates, the connecting block one and the connecting block two being installed in cooperation with the buckle cover, a support arranged inside the box body, symmetrical fixed holes arranged on the upper surface of the support, a rubber plate arranged at the bottom end of the box body, uniformly distributed placement tables arranged on the upper surface of the rubber plate, the placement tables being installed in cooperation with the vertically adjacent fixed holes, and a clamping and fixing module for fixing test tubes arranged between the support and the box body; and a rubber sleeve arranged inside each fixed hole.

[0006] As a further improvement of the utility model, the clamping and fixing module comprises fixed plates one symmetrically arranged on the upper side of the support, guide rails one symmetrically arranged between the two fixed plates one, sliding plates one uniformly arranged and sliding between the two guide rails one, rubber clamping blocks one uniformly arranged on the left side of the sliding plates one, fixed plates two symmetrically arranged on the lower side of the support, guide rails two symmetrically arranged between the two fixed plates two, sliding plates two uniformly arranged and sliding between the two guide rails two, rubber clamping blocks two uniformly arranged on the right side of the sliding plates two, the rubber clamping blocks one and the rubber clamping blocks two are respectively installed in cooperation with the adjacent fixed holes, and the support further comprises a driving unit for driving the rubber clamping blocks one and the rubber clamping blocks two to move.

[0007] As a further improvement of the utility model, the sealing ring is arranged on the side of the buckle cover close to the box body through an adhesive.

[0008] As a further improvement of the utility model, the lower surface four corners of the box body and the upper surface four corners of the box cover are both movably provided with corner cover sleeves through bolts.

[0009] Compared with the prior art, the utility model has the beneficial effects as follows:

[0010] Firstly, the test tubes to be replaced are sequentially inserted into the fixed holes, and the rubber sleeves on the fixed holes can effectively buffer the outer side of the test tubes.

[0011] Secondly, the inner hexagonal head is twisted by an external tool, so that the inner hexagonal head drives the rotating rod connected thereto to rotate, the rubber clamping blocks one and the rubber clamping blocks two on both sides of the fixed hole are moved towards each other, the test tubes inserted into the fixed hole are quickly and stably clamped and fixed, and different models can be quickly and firmly fixed when the test tubes in the box body need to be replaced.

[0012] Thirdly, the buckle cover is rotated, the buckle cover is buckled to the connecting blocks one and two, the buckle cover and the box body are fixed, and the sealing ring on the buckle cover seals the buckle cover and the box body.

[0013] Fourthly, the corner cover sleeves on the box body and the box cover can effectively protect the test tubes in the box body. BRIEF DESCRIPTION OF DRAWINGS

[0014] The utility model will be explained further in detail below in combination with the drawings and specific embodiments.

[0015] Figure 1 It is the internal structure schematic diagram of the utility model;

[0016] Figure 2 It is the internal structure schematic diagram of the utility model;

[0017] Figure 3 It is the internal structure schematic diagram of the utility model;

[0018] Figure 4 It is the internal structure schematic diagram of the utility model.

[0019] In the drawing: 101, box body;102, hinge;103, box cover;104, corner cover;105, connecting block one;106, rotating plate;107, buckle cover;108, support;109, rubber sleeve;110, rubber plate;111, placing table;201, fixed plate one;202, guide rail one;203, sliding plate one;204, rubber clamp block one;205, fixed plate two;206, guide rail two;207, sliding plate two;208, rubber clamp block two;209, drive plate one;210, drive plate two;211, rotating rod;301, internal hexagonal head. Specific embodiments

[0020] In order to better understand the utility model, the content of the utility model will be further clarified below in combination with examples, but the protection content of the utility model is not only limited to the following examples. In the following description, a large number of specific details are given to provide a more thorough understanding of the utility model. However, it is obvious to those skilled in the art that the utility model can be implemented without one or more of these details.

[0021] As Figure 1 , 4As shown in the figure, it comprises a box body 101, the rear side of the box body 101 is provided with symmetrically distributed hinges 102, the hinges 102 are rotatably provided with a box cover 103, the middle part of the box cover 103 is provided with a connecting block one 105, the middle part of the box body 101 is provided with a connecting block two, the front side of the box body 101 is rotatably provided with symmetrically distributed rotating plates 106, the rotating plates 106 are rotatably provided with a buckle cover 107 between the two rotating plates 106, the connecting block one 105 and the connecting block two are both installed in cooperation with the buckle cover 107, the inside of the box body 101 is provided with a support 108, the upper surface of the support 108 is provided with symmetrically distributed fixing holes, the inside bottom end of the box body 101 is provided with a rubber plate 110, the upper surface of the rubber plate 110 is provided with uniformly distributed placement tables 111, the placement tables 111 are respectively installed in cooperation with the vertically adjacent fixing holes, the support 108 and the box body 101 are further provided with a clamping and fixing module for fixing test tubes.

[0022] As shown in the figure, Figure 1 , 2 the inside of the fixing hole is provided with a rubber sleeve 109.

[0023] As shown in the figure, Figure 2 , 3 the clamping and fixing module comprises symmetrically arranged fixing plates one 201 on the upper side of the support 108, symmetrically distributed guide rails one 202 are arranged between the two fixing plates one 201, uniformly distributed sliding plates one 203 are slidably arranged between the two guide rails one 202, uniformly distributed rubber clamping blocks one 204 are arranged on the left side of the sliding plates one 203, symmetrically distributed fixing plates two 205 are arranged on the lower side of the support 108, symmetrically distributed guide rails two 206 are arranged between the two fixing plates two 205, uniformly distributed sliding plates two 207 are slidably arranged between the two guide rails two 206, uniformly distributed rubber clamping blocks two 208 are arranged on the right side of the sliding plates two 207, the rubber clamping blocks one 204 and the rubber clamping blocks two 208 are respectively installed in cooperation with the adjacent fixing holes, the support 108 is further provided with a driving unit for driving the rubber clamping blocks one 204 and the rubber clamping blocks two 208 to move; the driving unit comprises a driving plate one 209 arranged in the middle part of the lower surface of the sliding plate one 203, a driving plate two 210 is arranged in the middle part of the upper surface of the sliding plate two 207, a rotating rod 211 is rotatably arranged in the middle part of the inside of the box body 101, a plurality of uniformly distributed threads one are arranged on the outer side of the rotating rod 211, the threads one are respectively threadedly connected with the adjacent driving plates one 209, a plurality of uniformly distributed threads two are arranged on the outer side of the rotating rod 211, the threads two are respectively threadedly connected with the adjacent driving plates two 210, the box body 101 is further provided with a driving assembly for driving the rotating rod 211 to rotate; the driving assembly comprises an internal hexagonal head 301 arranged at the right end of the rotating rod 211, the box body 101 is further provided with an avoidance groove matched with the internal hexagonal head 301.

[0024] As shown in the figure, Figure 1 ,2 As shown, the buckle cover 107 is provided with a sealing ring close to one side of the box body 101.

[0025] In use, when the test tube installed on the support 108 needs to be replaced, the personnel will insert the test tube to be replaced into the fixing hole in sequence, and the outer side of the test tube can be effectively buffered through the rubber sleeve 109 on the fixing hole. Then the personnel will twist the inner hexagonal head 301 through external tools, so that the inner hexagonal head 301 drives the rotating rod 211 connected thereto to rotate, so that the rotating rod 211 drives the thread one and the thread two thereon to rotate, respectively, and then drives the sliding plate one 203 and the sliding plate two 207 located on both sides of the fixing hole to move through the threaded relationship between the thread one and the driving plate one 209 and the threaded relationship between the thread two and the driving plate two 210, so that the sliding plate one 203 drives the rubber clamp block one 204 connected thereto to move, respectively, and the sliding plate two 207 drives the rubber clamp block two 208 connected thereto to move, respectively, so that the rubber clamp block one 204 and the rubber clamp block two 208 located on both sides of the fixing hole approach each other, and the test tube inserted into the fixing hole is quickly and stably clamped and fixed. Different models can be quickly and firmly fixed when the detection test tube inside the box body needs to be replaced. Then the personnel rotates the buckle cover 107, so that the buckle cover 107 buckles the upper side of the box body 101. At this time, the connecting block one 105 and the connecting block two are integrated, and then the personnel rotates the buckle cover 107, so that the buckle cover 107 buckles the connecting block one 105 and the connecting block two, and then fixes the buckle cover 107 and the box body 101. The sealing ring on the buckle cover 107 seals the buckle cover 107 and the box body 101.

[0026] According to another embodiment of the present application, as shown in Figure 1 , 2 As shown, the lower surface of the box body 101 and the upper surface of the box cover 103 are both provided with corner covering sleeves 104. In actual use, the corner covering sleeves 104 on the box body 101 and the box cover 103 can effectively protect the test tubes inside.

[0027] Finally, it should be pointed out that the above embodiments are only used to illustrate the technical solutions of the present application and not to limit it. Other modifications or equivalent replacements to the technical solutions of the present application made by those skilled in the art should be covered in the scope of the claims of the present application, as long as they do not deviate from the spirit and scope of the technical solutions of the present application.

Claims

1. A diagnostic kit for typing a SnoRNA, comprising a box (101), characterized in that: The rear side of the box body (101) is provided with symmetrically distributed hinges (102), the hinges (102) are rotationally provided with a box cover (103) between them, the middle part of the box cover (103) is provided with a connecting block one (105), the middle part of the box body (101) is provided with a connecting block two, the front side of the box body (101) is rotationally provided with symmetrically distributed rotating plates (106), the two rotating plates (106) are rotationally provided with a buckle cover (107) between them, the connecting block one (105) and the connecting block two are both cooperatively installed with the buckle cover (107), the inside of the box body (101) is provided with a support (108), the upper surface of the support (108) is provided with symmetrically distributed fixing holes, the inside bottom end of the box body (101) is provided with a rubber plate (110), the upper surface of the rubber plate (110) is provided with uniformly distributed placement tables (111), the placement tables (111) are respectively cooperatively installed with the vertically adjacent fixing holes, the support (108) and the box body (101) are further provided with a clamping fixing module for fixing test tubes.

2. The SnoRNA typing diagnostic and detection kit as described in claim 1, characterized in that: The inside of the fixing hole is provided with a rubber sleeve (109).

3. The SnoRNA typing diagnostic and detection kit as described in claim 1, characterized in that: The clamping fixing module comprises symmetrically arranged fixing plates one (201) on the upper side of the support (108), symmetrically distributed guide rails one (202) are arranged between the two fixing plates one (201), uniformly distributed sliding plates one (203) are slidingly arranged between the two guide rails one (202), uniformly distributed rubber clamping blocks one (204) are arranged on the left side of the sliding plate one (203), symmetrically distributed fixing plates two (205) are arranged on the lower side of the support (108), symmetrically distributed guide rails two (206) are arranged between the two fixing plates two (205), uniformly distributed sliding plates two (207) are slidingly arranged between the two guide rails two (206), uniformly distributed rubber clamping blocks two (208) are arranged on the right side of the sliding plate two (207), the rubber clamping blocks one (204) and the rubber clamping blocks two (208) are respectively cooperatively installed with the adjacent fixing holes, and a driving unit for driving the rubber clamping blocks one (204) and the rubber clamping blocks two (208) to move is further arranged on the support (108).

4. The SnoRNA typing diagnostic and detection kit as described in claim 3, characterized in that: The driving unit comprises a driving plate one (209) arranged in the middle part of the lower surface of the sliding plate one (203), a driving plate two (210) is arranged in the middle part of the upper surface of the sliding plate two (207), a rotating rod (211) is rotationally arranged in the middle part of the inside of the box body (101), a plurality of uniformly distributed threads one are arranged on the outer side of the rotating rod (211), the threads one are respectively threadedly connected with the adjacent driving plates one (209), a plurality of uniformly distributed threads two are arranged on the outer side of the rotating rod (211), the threads two are respectively threadedly connected with the adjacent driving plates two (210), and a driving assembly for driving the rotating rod (211) to rotate is further arranged on the box body (101).

5. The SnoRNA typing diagnostic and detection kit as described in claim 4, characterized in that: The driving assembly comprises an internal hexagonal head (301) arranged at the right end of the rotating rod (211), and an avoiding groove matched with the internal hexagonal head (301) is further arranged on the box body (101).

6. The SnoRNA typing diagnostic and detection kit as described in claim 1, characterized in that: The side of the buckle cover (107) close to the box body (101) is provided with a sealing ring.

7. The SnoRNA typing diagnostic and detection kit as described in claim 1, characterized in that: The lower surface of the box body (101) and the upper surface of the box cover (103) are provided with corner cover sleeves (104).

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