Cell culture plate convenient to clean

Abstract

The utility model discloses a cell culture plate convenient to clean, and relates to the technical field of cell culture.The cell culture plate comprises a bottom plate and a pressing plate, the pressing plate is located over the bottom plate, and the bottom plate and the pressing plate are fixedly connected through a connecting assembly; a plurality of positioning circular grooves are formed in the bottom plate and are distributed at equal intervals; a plurality of round holes are formed in the pressing plate; a plurality of cylinders with two open ends are arranged between the pressing plate and the bottom plate, the lower edge openings of the cylinders abut against the positioning circular grooves in the corresponding positions, the upper edge openings of the cylinders are located in the circular holes in the corresponding positions, flanges are arranged on the outer sides of the cylinders and abut against the lower surface of the pressing plate, and the cylinders abut against the positioning circular grooves through the flanges by means of the pressing plate. According to the device, the cell culture plate can be split into a plurality of parts which are easy to clean, the dismounting and mounting processes are simple, and the plurality of parts do not have sanitary dead angles which are difficult to clean, so that the cleaning is more convenient.

Description

Technical Field

[0001] This application relates to the field of cell culture technology, and in particular to a cell culture plate that is easy to clean. Background Technology

[0002] Cell culture plates are biological instruments that can be divided into flat-bottomed and round-bottomed (U-shaped and V-shaped) cell culture plates based on their bottom shape. U-shaped plates are generally required because cells tend to cluster together in a small area due to gravity. V-shaped plates have fewer uses and are typically used in cell killing experiments to ensure close contact between target cells.

[0003] For example, a cell culture plate with patent number CN202320395576.7 has the following shortcomings in actual use:

[0004] The aforementioned device includes: a cell culture plate body, a cell culture plate cover, a locking block, and a cell culture tank; the cell culture plate cover is disposed on the cell culture plate body, and the cell culture plate cover is provided with a locking groove; the locking block is disposed on the cell culture plate body, and the cell culture plate cover and the cell culture plate body are detachably connected by the locking block; however, when cleaning this cell culture plate, it is necessary to clean the corners at the bottom of the culture tank, which is quite difficult. Summary of the Invention

[0005] To address the technical challenge of cleaning cell culture plates, this application provides a cell culture plate that is easy to clean.

[0006] The cell culture plate that is easy to clean provided in this application adopts the following technical solution:

[0007] A cell culture plate that is easy to clean includes a base plate and a pressure plate, the pressure plate being located directly above the base plate, and the base plate and the pressure plate being fixedly connected by a connecting assembly;

[0008] The base plate is provided with a plurality of positioning circular grooves, and the plurality of positioning circular grooves are distributed at equal intervals;

[0009] The pressure plate has several circular holes, and the circular holes are located directly above the corresponding positioning circular grooves;

[0010] Several cylinders with open ends are provided between the pressure plate and the base plate. The lower edge of the cylinder abuts in the corresponding positioning circular groove, and the upper edge is located in the corresponding circular hole. The outer side of the cylinder is provided with a flange, and the flange abuts against the lower surface of the pressure plate. The pressure plate presses the cylinder tightly into the positioning circular groove through the flange.

[0011] By adopting the above technical solution, the base plate and the pressure plate are fixed to each other by the connecting components, and the pressure plate presses the cylinder into the positioning circular groove of the base plate through the flange. The bottom of the cylinder is sealed by the base plate, and cell culture can be carried out inside the cylinder. Moreover, during cleaning, the connecting components can be removed, and the base plate and the pressure plate are both flat structures, which can be cleaned with a cleaning brush. Cleaning is convenient. In addition, the cylinder is open at both the top and bottom, and there are no corners that are difficult to clean, making cleaning even more convenient.

[0012] Preferably, the connecting assembly includes several connecting posts, the base plate has several first mounting holes, all of which are located at the gaps between several positioning circular grooves, the pressure plate has several second mounting holes, and the second mounting holes are located directly above the corresponding first mounting holes. The connecting posts pass through the corresponding first and second mounting holes, the bottom of the connecting posts is fixed with a wide head, and the wide head abuts against the bottom of the base plate. The connecting posts have positioning holes, and mounting rods are inserted between the positioning holes on the connecting posts in the same column, and the mounting rods abut against the upper surface of the pressure plate.

[0013] By adopting the above technical solution, the operator can pull out the installation rod from above to remove the pressure plate, and then separate the base plate and connecting column. No tools are needed for disassembly and installation, making the operation convenient.

[0014] Preferably, the wide head has a directional notch, and the lower surface of the base plate has the same number of directional protrusions as the first mounting holes, with the directional protrusions located on one side of the first mounting hole at the corresponding position, and the directional notch on the wide head is engaged with the directional protrusion.

[0015] By adopting the above technical solution, when installing the connecting column, the directional notch needs to be locked onto the directional protrusion to determine the installation angle of the connecting column, so that the positioning holes on the connecting columns in the same row can be aligned with the hooks, making it convenient to insert the installation rod.

[0016] Preferably, both ends of the mounting rod have chamfered edges.

[0017] By adopting the above technical solution, the chamfer can play a guiding role when inserting the installation rod, making the operation smoother.

[0018] Preferably, the base plate is provided with a cover, and the inner side wall of the cover is fitted with the edge of the pressure plate, and the two sides of the cover are provided with handle grooves.

[0019] By adopting the above technical solution, the cover can provide protection for cell culture, and the handle groove allows the cover to be removed upwards for easy operation.

[0020] Preferably, two symmetrically distributed handles are fixed on both sides of the base plate, and the handles are located on the outside of the cover.

[0021] By adopting the above technical solution, the cell culture plate can be more easily moved and transferred using the handle.

[0022] Preferably, a height-increasing anti-slip pad is provided under the base plate, and the thickness of the height-increasing anti-slip pad is greater than the thickness of the wide head.

[0023] By adopting the above technical solution, the heightening anti-slip pad can not only prevent the cell culture plate from sliding, but also lift the bottom plate to prevent the wide end from contacting the placement platform, thereby further improving the placement stability.

[0024] Preferably, the cross-section of the positioning circular groove is V-shaped, and the two inner walls of the positioning circular groove abut against the lower edge of the cylinder.

[0025] By adopting the above technical solution, the V-shaped cross-section makes it easier to press against the cylinder, thus improving the sealing effect.

[0026] In summary, this application includes at least one of the following beneficial technical effects:

[0027] 1. The cylinder is pressed onto the base plate and the pressure plate, and cell culture is carried out inside the cylinder. When cleaning is required, the base plate, the pressure plate and the cylinder can be slowly disassembled. The base plate and the pressure plate are both flat, making cleaning easier. Moreover, the cylinder has openings at both ends to clean hard-to-reach corners, making cleaning convenient as well. Attached Figure Description

[0028] Figure 1 This is a schematic diagram of the overall isometric structure of this application;

[0029] Figure 2 This is a schematic diagram of the structure after the cover is removed in this application;

[0030] Figure 3 This is a schematic diagram of the split structure of this application;

[0031] Figure 4 This is a schematic diagram of the bottom structure of the base plate in this application;

[0032] Figure 5 This is a schematic diagram of the cylinder structure in this application;

[0033] Figure 6 This is a schematic diagram of the connecting column in this application.

[0034] Reference numerals: 1. Base plate; 11. Positioning circular groove; 12. First mounting hole; 13. Orientation protrusion;

[0035] 2. Pressure plate; 21. Round hole; 22. Second mounting hole;

[0036] 3. Cylinder; 31. Flange;

[0037] 4. Connecting post; 41. Wide head; 42. Positioning hole; 43. Orientation notch;

[0038] 5. Install the rod;

[0039] 6. Lid; 61. Handle groove;

[0040] 7. Handle;

[0041] 8. Height-increasing anti-slip mat. Detailed Implementation

[0042] The following is in conjunction with the appendix Figure 1-6 This application will be described in further detail.

[0043] This application discloses a cell culture plate that is easy to clean.

[0044] Reference Figure 1 , 2 3, 4, 5, A cell culture plate that is easy to clean includes a base plate 1 and a pressure plate 2 located directly above the base plate 1. The two are fixed to each other by a detachable connecting component, and several equally spaced cylinders 3 are arranged between them. A positioning circular groove 11 is formed on the base plate 1. The positioning circular groove 11 has a V-shaped cross-section. The bottom of the cylinder 3 rests in the positioning circular groove 11, and the bottom of the cylinder 3 is sealed by the base plate 1, allowing cell culture to be carried out inside. A heightening anti-slip pad 8 is provided below the base plate 1 to prevent... To prevent the cell culture plate from sliding, a flange 31 is provided on the outer side of the cylinder 3, and multiple round holes 21 are provided on the pressure plate 2. The upper end of the cylinder 3 is located inside the round holes 21, and the lower edge of the round holes 21 will abut against the flange 31, pressing the cylinder 3 tightly onto the base plate 1 to improve the sealing effect. A cover 6 is provided on the base plate 1, and the inner side wall of the cover 6 is in contact with the edge of the pressure plate 2. Handle grooves 61 are provided on both sides of the cover 6 to facilitate the removal of the cover 6. Two symmetrically distributed handles 7 are fixed on both sides of the base plate 1, and the handles 7 are located on the outer side of the cover 6.

[0045] With the above configuration, the pressure plate 2 and the base plate 1 are fixed to each other by the connecting assembly. The pressure plate 2 presses on the flange 31, so that the lower end of the cylinder 3 abuts against the base plate 1. The base plate 1 seals the lower end of the cylinder 3, allowing cell culture to be carried out inside the cylinder 3. In addition, the cover 6 with a handle groove 61 protects the cylinder 3 and makes it easy to remove. The cell culture plate can also be transferred and transported by the handle 7. When cleaning is required, the connecting assembly can be disassembled, and then the pressure plate 2, the base plate 1 and the multiple cylinders 3 can be separated. During cleaning, the pressure plate 2 and the base plate 1 are in a flat state, making cleaning relatively simple. The cylinders 3 are also open at both ends, with no hard-to-clean corners, making cleaning convenient.

[0046] Reference Figure 2 , 34, 6. The base plate 1 has multiple first mounting holes 12, which are located in the gaps between several positioning circular grooves 11. The pressure plate 2 has multiple second mounting holes 22, which correspond to the positions of the first mounting holes 12. The connecting assembly includes multiple connecting posts 4 and mounting rods 5. The connecting posts 4 pass through the corresponding first mounting holes 12 and second mounting holes 22. The bottom of the connecting post 4 is fixed with a wide head 41, which rests against the bottom of the base plate 1. Several directional protrusions 13 are provided below the base plate 1. The wide head 41 has a directional notch 43. The directional protrusions 13 and the directional notch 43 cooperate to determine the installation direction of the connecting post 4. The connecting post 4 has positioning holes 42, which can be aligned with each other on the connecting posts 4 in the same row. The mounting rods 5 are inserted between the positioning holes 42 on the connecting posts 4 in the same row, and the mounting rods 5 abut against the upper surface of the pressure plate 2. The two ends of the mounting rods 5 are chamfered.

[0047] With the above setup, the cooperation of the mounting rods 5 and the connecting column 4 restricts the distance between the pressure plate 2 and the base plate 1. The cylinder 3 supports the base plate 1 and the pressure plate 2, achieving a fixing effect. When cleaning the cell culture plate, the operator can first pull out the multiple mounting rods 5 on the pressure plate 2 from one end. After pulling out all the mounting rods 5, the pressure plate 2 can be removed upwards. Then, the cylinder 3 can be separated, and the connecting column 4 can be pulled out from the bottom of the base plate 1 to complete the disassembly. Then, cleaning, disassembly, and dark rotation can be performed. No tools are needed for this process, making the operation more convenient and faster.

[0048] The implementation principle of the cell culture plate that is easy to clean according to the embodiment of this application is as follows: the cooperation of the mounting rod 5 and the connecting column 4 restricts the distance between the pressure plate 2 and the bottom plate 1, and the cylinder 3 supports the bottom plate 1 and the pressure plate 2 to achieve a fixing effect. The bottom of the cylinder 3 is sealed by the bottom plate 1, and cell culture can be carried out inside the cylinder 3. When cleaning is required, the mounting rod 5 can be pulled out from one side to separate the pressure plate 2, the cylinder 3 and the bottom plate 1 for cleaning. Moreover, both ends of the cylinder 3 are open, so there are no dead corners that are difficult to clean, making cleaning more convenient and thorough, and the cleaning effect is better.

[0049] In summary, this device can disassemble the cell culture plate into multiple easy-to-clean components. The disassembly and assembly process is simple, requires no tools, and the multiple components have no hard-to-clean corners, making cleaning more convenient.

[0050] The above are all preferred embodiments of this application, and are not intended to limit the scope of protection of this application. Therefore, all equivalent changes made in accordance with the structure, shape and principle of this application should be covered within the scope of protection of this application.

Claims

1. A cell culture plate that is easy to clean, comprising a base plate (1) and a pressing plate (2), wherein the pressing plate (2) is located directly above the base plate (1), characterized in that: The base plate (1) and the pressure plate (2) are fixedly connected by a connecting assembly; The base plate (1) is provided with a plurality of positioning circular grooves (11), and the plurality of positioning circular grooves (11) are distributed at equal intervals; The pressure plate (2) has several circular holes (21) and the circular holes (21) are located directly above the positioning circular groove (11) at the corresponding position; A plurality of cylinders (3) with open ends are provided between the pressure plate (2) and the base plate (1). The lower edge of the cylinder (3) abuts in the positioning circular groove (11) at the corresponding position, and the upper edge is located in the circular hole (21) at the corresponding position. A flange (31) is provided on the outer side of the cylinder (3), and the flange (31) abuts against the lower surface of the pressure plate (2). The pressure plate (2) presses the cylinder (3) against the positioning circular groove (11) through the flange (31).

2. The cell culture plate that is easy to clean according to claim 1, characterized in that: The connecting assembly includes several connecting posts (4), and several first mounting holes (12) are provided on the base plate (1). The first mounting holes (12) are all located in the gaps between several positioning circular grooves (11). Several second mounting holes (22) are provided on the pressure plate (2), and the second mounting holes (22) are located directly above the corresponding first mounting holes (12). The connecting posts (4) pass through the corresponding first mounting holes (12) and second mounting holes (22). A wide head (41) is fixed at the bottom of the connecting post (4), and the wide head (41) abuts against the bottom of the base plate (1). A positioning hole (42) is provided on the connecting post (4). An installation rod (5) is inserted between the positioning holes (42) on the connecting posts (4) in the same row, and the installation rod (5) abuts against the upper surface of the pressure plate (2).

3. The cell culture plate that is easy to clean according to claim 2, characterized in that: The wide head (41) has a directional notch (43), and the lower surface of the base plate (1) has the same number of directional protrusions (13) as the first mounting holes (12). The directional protrusions (13) are located on one side of the first mounting holes (12) at the corresponding positions, and the directional notch (43) on the wide head (41) is engaged with the directional protrusions (13).

4. The cell culture plate that is easy to clean according to claim 2, characterized in that: Both ends of the mounting rod (5) are chamfered.

5. The cell culture plate that is easy to clean according to claim 1, characterized in that: The base plate (1) is provided with a cover (6), and the inner side of the side wall of the cover (6) is attached to the edge of the pressure plate (2). The cover (6) has handle grooves (61) on both sides.

6. The cell culture plate that is easy to clean according to claim 5, characterized in that: Two symmetrically distributed handles (7) are fixed on both sides of the base plate (1), and the handles (7) are located on the outside of the cover (6).

7. The cell culture plate that is easy to clean according to claim 2, characterized in that: A height-increasing anti-slip pad (8) is provided below the base plate (1), and the thickness of the height-increasing anti-slip pad (8) is greater than the thickness of the wide head (41).

8. The cell culture plate that is easy to clean according to claim 1, characterized in that: The cross-section of the positioning circular groove (11) is V-shaped, and the two inner walls of the positioning circular groove (11) abut against the lower edge of the cylinder (3).

Images