Tissue extraction needle for mouse experiment
By introducing a locking component and guide groove design into the tissue extraction needle used in mouse experiments, the problem of needle loosening and falling off was solved, achieving a stable connection and convenient disassembly, thus improving experimental efficiency and applicability.
Patent Information
- Application Number
- CN202422467997.3
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-10-12
- Publication Date
- 2025-11-18
- Estimated Expiration
- 2034-10-12
AI Technical Summary
The needles used in existing mouse experiments are prone to loosening or falling off due to external force, which affects experimental efficiency.
The device employs a locking assembly, including a limiting block, a guide block, a spring, and a support ring. When the needle is inserted, the limiting block is squeezed to reset and lock into place. Combined with the design of multiple guide grooves and guide rods, a stable connection of the needle is achieved.
This improves the installation stability of the needle, prevents loosening and falling off, enhances experimental efficiency, and facilitates the removal and replacement of the needle, thus improving the convenience and applicability of the device.
Smart Images
Figure CN223555001U_ABST
Abstract
Description
TECHNICAL FIELD
[0001] The utility model relates to mouse experiment field especially, it is a mouse experiment with tissue extraction needle. BACKGROUND
[0002] In the field of life science research, mouse experiment as an important research means provides key experimental basis for revealing life phenomenon, exploring disease mechanism and developing new treatment method, wherein, the research on nerve tissue has been one of the hotspots, and the subphrenic vagus nerve tissue becomes the key attention object of numerous researches due to its unique role in physiological regulation.
[0003] The vagus nerve is one of the most complex nerves in human and animal bodies, which interacts with multiple organ systems and participates in the regulation of important physiological functions such as respiration, digestion, cardiovascular system, etc.
[0004] At present, the subphrenic vagus nerve tissue is mainly extracted by the traditional tissue extraction needle in mouse experiment, and the needle head of the existing tissue extraction needle is usually connected with the needle body by inserting, and the inserting connection mode is not stable enough during use, and the needle head may be loose or even fall off due to external force during the extraction process, thereby affecting the normal progress of the experiment and reducing the experimental efficiency, so the mouse experiment tissue extraction needle is proposed to solve the above problems. UTILITY MODEL CONTENT
[0005] In order to make up for the above shortcomings, the utility model provides a mouse experiment tissue extraction needle, which aims at improving the problem of "the needle head is installed by inserting, which is easy to be loose or fall off during use, affecting the experiment" in the prior art.
[0006] In order to achieve the above purpose, the utility model adopts the following technical scheme: a mouse experiment tissue extraction needle, comprising a needle body, a piston shaft is inserted into the inner wall of the needle body, a connecting port is fixedly connected to the bottom end of the needle body, a needle head is inserted into the outer wall of the bottom end of the needle body close to the connecting port, a clamping assembly is arranged on the outer wall of the bottom end of the needle body close to the needle head, the clamping assembly comprises a limiting block, the top end of the limiting block is fixedly connected with a guide block, a supporting ring is fixedly connected to the bottom outer wall of the needle body, the guide block penetrates and is slidingly connected to the bottom end of the supporting ring, the guide block and the supporting ring are elastically connected through a spring, and a sliding groove is formed in the bottom end of the supporting ring.
[0007] As a further description of the above technical scheme:
[0008] The upper part of the lower part of the needle body close to the supporting ring is provided with a removal assembly, the removal assembly comprises a guide ring, the guide ring is rotatably connected to the outer wall of the needle body close to the upper part of the supporting ring, and a guide groove is formed in the bottom end of the guide ring.
[0009] As a further description of the above technical solutions:
[0010] A positioning groove is formed in the middle of the right inner wall of the sliding groove, a sliding block is fixedly connected to the right side of the guide block, the sliding block is slidingly connected to the inner wall of the positioning groove, and one end of the spring is fixedly connected to the front surface of the guide block.
[0011] As a further description of the above technical solutions:
[0012] The other end of the spring is fixedly connected to the front surface of the inner wall of the sliding groove, the bottom end of the limiting block is provided as an inclined surface, the limiting block, the guide block, the spring and the sliding groove are provided in multiple groups, and the multiple groups of the limiting block, the guide block, the spring and the sliding groove are arranged in a circular array with the center point of the needle body as the center.
[0013] As a further description of the above technical solutions:
[0014] The guide groove is provided in an arc shape, and a guide rod is fixedly connected to the top end of the guide block.
[0015] As a further description of the above technical solutions:
[0016] The guide rod is slidingly connected to the inner wall of the guide groove, and a positioning ring is fixedly connected to the top of the outer wall of the needle body close to the guide ring.
[0017] As a further description of the above technical solutions:
[0018] The positioning ring and the guide ring are elastically connected through a torsion spring, one end of the torsion spring is fixedly connected to the bottom end of the positioning ring, the other end of the torsion spring is fixedly connected to the top end of the guide ring, the guide groove and the guide rod are provided in multiple groups, and the multiple groups of the guide groove and the guide rod are arranged in a circular array with the center point of the needle body as the center.
[0019] As a further description of the above technical solutions:
[0020] The outer wall of the guide ring is fixedly connected with a plurality of protrusions and is provided with multiple groups, and the multiple groups of the protrusions are arranged in a circular array with the center point of the guide ring as the center.
[0021] The utility model has the advantages of the following beneficial effects:
[0022] 1、In the utility model, the needle is inserted after being aligned with the connecting port, the inclined surface of the limiting block is pressed by the needle at this time, the limiting block moves outward to press the spring, the needle is clamped by the limiting block quickly when the needle is clamped into the top end of the limiting block, the needle is clamped quickly, the needle is prevented from loosening and falling off, and the stability of installation and the experimental efficiency are improved.
[0023] 2、The utility model discloses, through the rotation of the guide groove is driven by the rotation guide ring, through the extrusion of multiple sets of guide grooves rotation and press multiple sets of guide rods, can drive multiple sets of guide block to move outward, simultaneously drive multiple sets of limit block to move outward and slide out needle head, at this moment, the limit of needle head can be quickly removed, thereby conveniently to the needle head is dismantled or replaced, improved the convenience and applicability of device. BRIEF DESCRIPTION OF DRAWINGS
[0024] Figure 1 It is the three-dimensional structure schematic diagram of the whole device in the utility model;
[0025] Figure 2 It is the three-dimensional structure split schematic diagram of needle head in the utility model;
[0026] Figure 3 It is the three-dimensional structure section view schematic diagram of needle body and support ring in the utility model;
[0027] Figure 4 It is the three-dimensional structure section view schematic diagram of needle body and support ring in the utility model.
[0028] LEGEND:
[0029] 1, needle body;2, piston shaft;3, needle head;4, support ring;5, guide ring;6, connecting port;41, limit block;42, guide block;43, sliding slot;44, sliding block;45, spring;51, protruding block;52, positioning ring;53, torsion spring;54, guide groove;55, guide rod. DETAILED DESCRIPTION
[0030] The technical scheme in the embodiments of the utility model will be described clearly and completely below in conjunction with the drawings in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by those skilled in the art without creative labor fall within the scope of the utility model.
[0031] REFERENCE Figure 1 , Figure 2 and Figure 3The utility model provides an embodiment: a kind of tissue extraction needle for mouse experiment, including needle body 1, needle body 1 whole is smaller, only suitable for mouse experiment use, piston shaft 2 is inserted in the inner wall of needle body 1, piston shaft 2 can be extracted by push-pull operation, negative pressure or positive pressure is generated in needle body 1, to realize the aspiration or push of diaphragmatic vagus nerve tissue, the bottom end of needle body 1 is fixedly connected with the connecting port 6 of being connected with needle head 3 conveniently, needle head 3 is inserted in the outer wall of the bottom end of needle body 1 close to connecting port 6, the sharp front end of needle head 3 can be easily inserted into the tissue in mouse body, accurately reach the position of diaphragmatic vagus nerve tissue and carry out tissue extraction, the outer wall of the bottom end of needle body 1 close to needle head 3 is provided with clamping assembly, clamping assembly includes limit block 41, the bottom end of limit block 41 is provided as inclined plane, when needle head 3 is inserted into needle body 1, the outer wall of needle head 3 will extrude the inclined plane of limit block 41, and limit block 41 is extruded and moves outward spring 45, when needle head 3 is completely inserted, limit block 41 will reset under the action of spring 45, tightly clamps needle head 3, to prevent loosening or falling off.
[0032] Further, the top end of limit block 41 is fixedly connected with guide block 42 that supports limit block 41 and drives limit block 41 to move, the bottom outer wall of needle body 1 is fixedly connected with support ring 4 that provides support, guide block 42 penetrates and is slidably connected at the bottom end of support ring 4, and guide block 42 and support ring 4 are elastically connected by spring 45, when the bottom end inclined plane of limit block 41 is extruded and moves outward, limit block 41 will be extruded and reset by the reverse force of spring 45, and the reverse force of spring 45 can make limit block 41 reset and clamp needle head 3, the bottom end of support ring 4 is provided with sliding slot 43, and sliding slot 43 provides the space of guide block 42 movement and cooperates with positioning groove and slider 44 to support guide block 42.
[0033] Referring to Figure 1 , Figure 2 and Figure 3 , the lower part of needle body 1 is provided with dismantling assembly close to the top of support ring 4, and the dismantling assembly includes guide ring 5 that drives multiple guide grooves 54 to rotate, guide ring 5 is rotatably connected to the outer wall of needle body 1 close to the top of support ring 4, and guide groove 54 penetrates and is provided in the bottom end of guide ring 5, when guide ring 5 rotates, guide groove 54 will drive guide rod 55 to move, so that limit block 41 moves outward, unclamps needle head 3, so that the dismantling of needle head 3 is more convenient and fast.
[0034] Referring to Figure 2 , Figure 3 and Figure 4The middle part of the right inner wall of the sliding slot 43 is provided with a positioning groove, the positioning groove supports the guide block 42 in cooperation with the sliding block 44, the right side of the guide block 42 is fixedly connected with the sliding block 44 supporting the guide block 42, the sliding block 44 is slidingly connected to the inner wall of the positioning groove, one end of the spring 45 is fixedly connected to the front surface of the guide block 42, the other end of the spring 45 is fixedly connected to the inner wall front surface of the sliding slot 43, the bottom end of the limiting block 41 is provided as a slope, by setting the bottom end of the limiting block 41 as a slope, when the needle 3 extrudes the slope of the limiting block 41, the limiting block 41 can be moved outward to drive the guide block 42 to move and extrude the spring 45, so that the needle 3 can be conveniently installed, after the insertion is completed, the limiting block 41 is reset to clamp and limit the needle 3 by the reverse force of the spring 45 being extruded, the insertion method is continuously used, the stability of installation is enhanced, and the effect of preventing falling is enhanced, the limiting block 41, the guide block 42, the spring 45 and the sliding slot 43 are provided with multiple groups, and the multiple groups of the limiting block 41, the guide block 42, the spring 45 and the sliding slot 43 are arranged in a circular array with the center point of the needle body 1 as the center, and multiple groups are arranged to increase the stability of overall limiting.
[0035] With reference to Figure 1 , Figure 2 and Figure 3 , the guide groove 54 is provided in an arc shape, by setting the guide groove 54 in an arc shape, the guide rod 55 can be extruded when rotating, so that the guide rod 55 moves outward to drive the guide block 42 and the limiting block 41 to move outward, so that the limiting of the needle 3 can be quickly released, and the disassembly is more convenient, the top end of the guide block 42 is fixedly connected with the guide rod 55 driving the guide block 42 to move, the guide rod 55 is slidingly connected to the inner wall of the guide groove 54, and the outer wall of the needle body 1 near the top of the guide ring 5 is fixedly connected with the positioning ring 52 supporting the torsional spring 53.
[0036] With reference to Figure 1 , Figure 2 and Figure 3The positioning ring 52 is elastically connected with the guide ring 5 through the torsion spring 53, one end of the torsion spring 53 is fixedly connected to the bottom end of the positioning ring 52, the other end of the torsion spring 53 is fixedly connected to the top end of the guide ring 5, the torsion spring 53 is extruded by rotating the guide ring 5 to drive the multiple sets of guide grooves 54 to rotate, the multiple sets of guide grooves 54 extrude the multiple sets of guide rods 55, the multiple sets of guide rods 55 drive the multiple sets of guide blocks 42 and the limiting blocks 41 to move outward to extrude the springs 45, when the needle 3 is moved out, the limiting of the needle 3 can be quickly released, at the same time, the reverse force of the extruded torsion spring 53 and the reverse force of the extruded spring 45 can quickly reset the limiting blocks 41 and the guide ring 5, facilitating the next installation and use, the guide grooves 54 and the guide rods 55 are provided in multiple sets and are arranged in a circular array with the center point of the needle body 1 as the center, the outer wall of the guide ring 5 is fixedly connected with the multiple sets of protrusions 51, the multiple sets of protrusions 51 can increase the friction force, thereby increasing the convenience of rotation and preventing sliding, the multiple sets of protrusions 51 are arranged in a circular array with the center point of the guide ring 5 as the center, the multiple sets of protrusions 51 can conveniently correspond to the multiple sets of limiting blocks 41, at the same time, the limiting of the needle 3 can be conveniently released, thereby the different needle 3 can be conveniently replaced, the convenience and applicability are improved.
[0037] Working principle: when the needle 3 is inserted into the bottom of the needle body 1 close to the outer wall of the connecting port 6 during use, the outer wall of the needle 3 first contacts the bottom end of the limiting block 41, due to the design of the inclined surface, the insertion force of the needle 3 moves the limiting block 41 outward, the limiting block 41 drives the guide block 42 to slide in the sliding groove 43 at the bottom end of the supporting ring 4, at the same time, the spring 45 is extruded, as the needle 3 continues to be inserted, when it is completely in place, the reverse force of the spring 45 pushes the guide block 42 and the limiting block 41 to reset, so that the limiting block 41 tightly clamps the needle 3 to prevent it from loosening or falling off, the multiple sets of limiting blocks 41, guide blocks 42, springs 45 and sliding grooves 43 are arranged in a circular array with the center point of the needle body 1 as the center, further increasing the stability of clamping the needle 3.
[0038] When the needle 3 needs to be removed at the end of the experiment, the guide ring 5 is rotated by rotating the plurality of protrusions 51 on the outer wall of the guide ring 5, and when the guide ring 5 is rotated, the torsion spring 53 is compressed, the guide groove 54 drives the guide rod 55 to move outward, thereby driving the guide block 42 and the limiting block 41 connected thereto to move outward, compressing the spring 45, and the plurality of guide grooves 54 and guide rods 55 are arranged in a circular array with the center point of the needle body 1 as the center, which can simultaneously drive a plurality of limiting blocks 41 to move outward, quickly release the clamping of the needle 3, at this time, the needle 3 can be easily pulled out of the needle body 1, and when the needle 3 is removed, the reverse force of the spring 45 and the torsion spring 53 will quickly reset the limiting block 41 and the guide ring 5, facilitating the next installation and use, so that different needles 3 can be conveniently replaced, improving the convenience and applicability of the extraction needle.
[0039] Finally, it should be noted that: the above only for the preferred embodiments of the present application, and not for limiting the present application, although the present application has been described in detail with reference to the foregoing embodiments, for those skilled in the art, it can still modify the technical solutions recorded in the foregoing embodiments, or make equivalent replacement for part of the technical features, any modification, equivalent replacement, improvement, etc. within the spirit and principles of the present application, should be included in the protection scope of the present application.
Claims
1. A tissue extraction needle for use in mouse experiments comprising a needle body (1), characterized in that: The inner wall of the needle body (1) is inserted with a piston shaft (2), the bottom end of the needle body (1) is fixedly connected with a connecting port (6), the outer wall of the bottom end of the needle body (1) close to the connecting port (6) is inserted with a needle (3), and the outer wall of the bottom end of the needle body (1) close to the needle (3) is provided with a clamping assembly, the clamping assembly comprises a limiting block (41), the top end of the limiting block (41) is fixedly connected with a guide block (42), the bottom outer wall of the needle body (1) is fixedly connected with a supporting ring (4), the guide block (42) penetrates and is slidingly connected at the bottom end of the supporting ring (4), and the guide block (42) and the supporting ring (4) are elastically connected through a spring (45).
2. The tissue extraction needle for mouse experiment according to claim 1, characterized in that: The upper side of the supporting ring (4) is provided with a clamping assembly, the clamping assembly comprises a guide ring (5), the guide ring (5) is rotatably connected to the outer wall of the needle body (1) above the supporting ring (4), and the bottom end of the guide ring (5) penetrates and is provided with a guide groove (54).
3. The tissue extraction needle for mouse experiment according to claim 1, characterized in that: The right side of the sliding groove (43) is provided with a positioning groove, the right side of the guide block (42) is fixedly connected with a sliding block (44), the sliding block (44) is slidingly connected to the inner wall of the positioning groove, and one end of the spring (45) is fixedly connected to the front surface of the guide block (42).
4. The tissue extraction needle for mouse experiment according to claim 1, characterized in that: The other end of the spring (45) is fixedly connected to the inner wall of the sliding groove (43), the bottom end of the limiting block (41) is provided as an inclined surface, the limiting block (41), the guide block (42), the spring (45) and the sliding groove (43) are provided in multiple groups, and the multiple groups of the limiting block (41), the guide block (42), the spring (45) and the sliding groove (43) are arranged in a circular array with the center point of the needle body (1) as the center.
5. The tissue extraction needle for mouse experiment according to claim 2, characterized in that: The guide groove (54) is provided in an arc shape, and the top end of the guide block (42) is fixedly connected with a guide rod (55).
6. The tissue extraction needle for mouse experiment according to claim 5, characterized in that: The guide rod (55) is slidingly connected to the inner wall of the guide groove (54), and the outer wall of the needle body (1) close to the top of the guide ring (5) is fixedly connected with a positioning ring (52).
7. The tissue extraction needle for mouse experiments according to claim 6, characterized in that: The positioning ring (52) and the guide ring (5) are elastically connected through a torsion spring (53), one end of the torsion spring (53) is fixedly connected to the bottom end of the positioning ring (52), the other end of the torsion spring (53) is fixedly connected to the top end of the guide ring (5), the guide groove (54) and the guide rod (55) are provided in multiple groups, and the multiple groups of the guide groove (54) and the guide rod (55) are arranged in a circular array with the center point of the needle body (1) as the center.
8. The tissue extraction needle for mouse experiment according to claim 2, characterized in that: The outer wall of the guide ring (5) is fixedly connected with a protruding block (51) and is provided in multiple groups, and the multiple groups of the protruding block (51) are arranged in a circular array with the center point of the guide ring (5) as the center.