Automatic integrated device for separating white blood cells

Abstract

The utility model discloses an automatic integrated device for separating white blood cells, which relates to the technical field of white blood cell separation, and comprises a support frame and a separation vessel, the top of the support frame is rotatably provided with a vertical pipe in a penetrating manner, the top of the vertical pipe is communicated with a liquid guide pipe, the bottom of the vertical pipe is communicated with a vessel cover, and the vessel cover covers the outer side of the separation vessel. A sealing slope is arranged in a pipe opening of the liquid guide pipe, a sealing block is arranged on the inner wall of the sealing slope in a contact mode, and an elastic limiting mechanism used for limiting the position of the sealing block is arranged between the sealing block and the interior of the liquid guide pipe. After a blood sample enters the separation vessel, the top of the separation vessel can be effectively sealed, external impurities are prevented from entering the separation vessel through air flow in the leukocyte separation process as much as possible, and it is guaranteed that the whole leukocyte separation work is clean enough.

Description

TECHNICAL FIELD

[0001] The utility model relates to the leukocyte separation technical field, concretely relates to an automatic integrated device of separating leukocyte. BACKGROUND

[0002] White blood cells are an important part of the immune system, which contains a variety of complex cellular structures and molecular mechanisms, and in the process of blood disease diagnosis and immune-related disease diagnosis, white blood cells in the blood need to be separated and effectively detected.

[0003] Through the search, the patent file with the announcement number CN211838513U discloses a disposable leukocyte-removing single blood cell separator, the device discharges the cell liquid after centrifugation through the discharge pipe, the damping spring provides the buffer force, avoids the damage caused by the rigid connection of the working cylinder during the work centrifugation, protects the working cylinder, adjusts the height of the device through the hydraulic cylinder, and meets the use of workers of different heights.

[0004] But the above-mentioned device carries out white blood cell separation, the pipeline for conveying blood is opened, so that the sundries dust in the external air can easily enter the separation dish through the pipeline when the white blood cells are centrifuged, so that the blood sample is contaminated and the white blood cell separation effect is affected. UTILITY MODEL CONTENT

[0005] In view of the above-mentioned problems existing in the prior art automatic integrated device for separating white blood cells, the utility model is proposed.

[0006] Therefore, the utility model aims at providing an automatic integrated device for separating white blood cells, which solves the problem that external dust sundries can easily enter the blood through the pipeline to contaminate the blood sample and affect the separation effect during white blood cell separation.

[0007] In order to achieve the above-mentioned purpose, the utility model provides the following technical scheme:

[0008] An automatic integrated device for separating white blood cells, comprising a support frame and a separation dish, a vertical pipe is rotatably arranged on the top of the support frame, a liquid guide pipe is communicated with the top of the vertical pipe, and a dish cover is communicated with the bottom of the vertical pipe and covers the outer side of the separation dish.

[0009] A sealing slope is arranged in the pipe opening of the liquid guide pipe, a sealing block is arranged on the inner wall of the sealing slope, and an elastic limiting mechanism is arranged between the sealing block and the inner part of the liquid guide pipe to limit the position of the sealing block.

[0010] Preferably, the elastic limiting mechanism comprises a horizontal rod fixedly arranged in the liquid guide pipe, a rod wall of the horizontal rod fixedly sleeved with an inner tube, an outer tube slidably sleeved with the outer tube, a bottom of the outer tube fixedly arranged with a connecting plate, the connecting plate fixedly connected with a sealing block, and a spring fixedly arranged between inner walls of the outer tube and the inner tube.

[0011] Preferably, a sealing ring is fixedly arranged at a pipe opening of the outer tube, and the sealing ring is sleeved with the outer tube.

[0012] Preferably, a thread is arranged at an upper end of an outer wall of the separation dish, and the thread is threadedly arranged in the inner part of the dish cover.

[0013] Further, a control motor is fixedly arranged at a top of the support frame, an output shaft of the control motor penetrates into the support frame and is fixedly arranged with a driving gear, a transmission gear is fixedly sleeved with an outer wall of the vertical pipe, and the driving gear and the transmission gear are arranged in a matched mode.

[0014] Preferably, a sealing plate is rotatably arranged at a lower end of an inner wall of the vertical pipe, a rotating rod is rotatably arranged at a side of the vertical pipe, an end of the rotating rod penetrates into the vertical pipe and is fixedly connected with the sealing plate, a damping sleeve is fixedly sleeved with an outer wall of the vertical pipe, the rotating rod is rotatably arranged in the damping sleeve, and a knob is fixedly arranged at an end of the rotating rod.

[0015] Preferably, elastic telescopic rods are fixedly arranged at two sides of an inner wall of the support frame, a guide plate is fixedly arranged at an end of the elastic telescopic rod, and a plurality of spaced-apart rolling balls are rollingly arranged in an inner wall of the guide plate.

[0016] Preferably, two symmetrically arranged pushing blocks are fixedly arranged at an outer wall of the separation dish.

[0017] Preferably, the liquid guide pipe is a flexible pipe.

[0018] In the above technical solution, the technical effects and advantages of the present application are as follows:

[0019] 1. The support frame, the vertical pipe, the dish cover, the separation dish, the liquid guide pipe, the sealing slope, the sealing block, the elastic limiting mechanism and the sealing plate can effectively seal the top of the separation dish after the blood sample enters the separation dish, so as to avoid external impurities from entering the separation dish through air flow during the process of white blood cell separation, and ensure that the whole white blood cell separation process is clean.

[0020] 2. The control motor, the driving gear, the transmission gear, the guide plate, the rolling balls and the elastic telescopic rod can make the separation dish rotate stably and quickly, and complete the rapid separation of white blood cells under the centrifugal effect. BRIEF DESCRIPTION OF DRAWINGS

[0021] In order to make the technical scheme of the embodiments of the present application or the prior art clearer, the accompanying drawings needed in the embodiments will be briefly introduced as follows. Obviously, the accompanying drawings in the following description only represent some embodiments described in the present application, and other drawings can also be obtained by those skilled in the art based on these drawings.

[0022] Figure 1 It is a structural schematic diagram of the present application;

[0023] Figure 2 It is a structural schematic diagram of the present application Figure 1 It is an enlarged schematic diagram of A part of the present application;

[0024] Figure 3 It is a three-dimensional structural schematic diagram of the outer tube and the inner tube of the present application;

[0025] Figure 4 It is a structural schematic diagram of the present application Figure 1 It is an enlarged schematic diagram of B part of the present application;

[0026] Figure 5 It is a top view structural schematic diagram of the guide plate of the present application.

[0027] Explanation of reference signs:

[0028] 1, support frame; 2, separation dish; 3, vertical pipe; 4, liquid guide pipe; 5, dish cover; 6, sealing slope; 7, sealing block; 8, cross rod; 9, inner tube; 10, outer tube; 11, connecting plate; 12, spring; 13, sealing ring; 14, control motor; 15, driving gear; 16, transmission gear; 17, sealing plate; 18, rotating rod; 19, damping sleeve; 20, knob; 21, elastic telescopic rod; 22, guide plate; 23, ball; 24, pushing block. DETAILED DESCRIPTION

[0029] In order to make the technical scheme of the present application better understood by those skilled in the art, the present application will be further described in detail with reference to the accompanying drawings.

[0030] The embodiment of the present application discloses an automatic integrated device for separating white blood cells.

[0031] Embodiment 1

[0032] The present application provides a device for separating white blood cells Figures 1-5An automated integrated device for separating leukocytes is shown, comprising a support frame 1 and a separation dish 2. A vertical tube 3 is rotatably inserted through the top of the support frame 1. A liquid guide tube 4 is connected to the top of the vertical tube 3. The liquid guide tube 4 is a flexible tube. A dish cover 5 is connected to the bottom of the vertical tube 3. The dish cover 5 covers the outside of the separation dish 2. The upper end of the outer wall of the separation dish 2 is threaded and threaded inside the dish cover 5. Two symmetrically arranged push blocks 24 are fixed on the outer wall of the separation dish 2.

[0033] A sealing bevel 6 is provided inside the opening of the liquid guide tube 4. A sealing block 7 is provided in contact with the inner wall of the sealing bevel 6. An elastic limiting mechanism for limiting the position of the sealing block 7 is provided between the sealing block 7 and the inside of the liquid guide tube 4. The elastic limiting mechanism includes a crossbar 8, which is fixedly installed inside the liquid guide tube 4. An inner tube 9 is fixedly sleeved on the wall of the crossbar 8. An outer tube 10 is slidably sleeved on the outside of the inner tube 9. A sealing ring 13 is fixedly installed at the opening of the outer tube 10. The sealing ring 13 is sleeved on the outside of the inner tube 9. A connecting plate 11 is fixedly installed at the bottom of the outer tube 10. The connecting plate 11 is fixedly connected to the sealing block 7. A spring 12 is fixedly installed between the inner walls of the outer tube 10 and the inner tube 9.

[0034] In its normal state, the separation dish 2 is threaded at the lower end of the lid 5. Simultaneously, the sealing block 7, pushed by the spring 12, contacts the sealing inclined surface 6, sealing the opening of the liquid guide tube 4. When leukocyte separation is required, the end of a test tube containing a blood sample can be inserted into the liquid guide tube 4, and the sealing block 7 is pushed. This causes the sealing block 7 to open the opening of the liquid guide tube 4 through the sliding cooperation of the outer tube 10 and the inner tube 9. Blood can then flow through the liquid guide tube 4 into the vertical tube 3 and ultimately into the separation dish 2. After the blood has drained, the spring 12 returns to its original position, pushing the sealing block 7 into the sealing inclined surface 6, thus sealing the opening of the liquid guide tube 4. Therefore, during separation, impurities in the external air cannot enter the separation dish 2 through the liquid guide tube 4, ensuring a clean separation environment and improving the leukocyte separation effect.

[0035] Example 2

[0036] Example 2, based on Example 1, aims to ensure stable separation of white blood cells by allowing the separation dish 2 to rotate stably. Figure 1 and Figure 5 As shown, a control motor 14 is fixedly installed on the top of the support frame 1. The output shaft of the control motor 14 passes through the support frame 1 and is fixedly installed with a drive gear 15. A transmission gear 16 is fixedly sleeved on the outer wall of the vertical tube 3. The drive gear 15 and the transmission gear 16 are configured to cooperate. Elastic telescopic rods 21 are fixedly installed on both sides of the inner wall of the support frame 1. A guide plate 22 is fixedly installed at the end of the elastic telescopic rod 21. A plurality of spaced ball bearings 23 are rolled and embedded in the inner wall of the guide plate 22.

[0037] When the blood sample is located in the separation dish 2, the control motor 14 is started to drive the driving gear 15 to rotate, and the separation dish 2 is driven to rotate under the support of the support frame 1, so that the white blood cells in the separation dish 2 can be separated under the centrifugal action, and the elastic telescopic rod 21 pushes the guide plates 22 to make the two guide plates 22 abut against the separation dish 2 to make the separation dish 2 rotate stably.

[0038] Embodiment 3

[0039] In order to reduce the large range splashing of the blood sample during the separation of the white blood cells, the embodiment 3 is based on the embodiment 1, as shown in Figure 1 and Figure 4 The lower end of the inner wall of the vertical pipe 3 is rotatably connected with the sealing plate 17, the side of the vertical pipe 3 is rotatably connected with the rotating rod 18, the end of the rotating rod 18 penetrates into the vertical pipe 3 and is fixedly connected with the sealing plate 17, the outer wall of the vertical pipe 3 is fixedly sleeved with the damping sleeve 19, the rotating rod 18 penetrates into the damping sleeve 19, and the end of the rotating rod 18 is fixedly provided with the knob 20.

[0040] When the blood sample completely enters the separation dish 2, the rotating rod 18 is driven to rotate under the driving of the knob 20, so that the rotating rod 18 drives the sealing plate 17 to rotate, and the sealing plate 17 can be rotated to the horizontal position and block the lower end of the inside of the vertical pipe 3, so that the blood sample cannot splash in a large range during the separation process, and the quality of the separation of the white blood cells is ensured.

[0041] The above only describes some exemplary embodiments of the present application by way of illustration, without doubt, for ordinary skilled in the art, without departing from the spirit and scope of the present application, the described embodiments can be modified in various ways. Therefore, the above drawings and description are illustrative in nature and should not be understood as limiting the scope of protection of the present application.

Claims

1. An automated integrated device for separating leukocytes, comprising a support frame (1) and a separation dish (2), characterized in that, The top of the support frame (1) is rotatably connected to a vertical tube (3), the top of the vertical tube (3) is connected to a liquid guide tube (4), the bottom of the vertical tube (3) is connected to a dish cover (5), and the dish cover (5) is placed on the outside of the separation dish (2). The inside of the liquid guide tube (4) is provided with a sealing slope (6), and the inner wall of the sealing slope (6) is in contact with a sealing block (7). An elastic limiting mechanism for limiting the position of the sealing block (7) is provided between the sealing block (7) and the inside of the liquid guide tube (4).

2. The automated integrated device for separating leukocytes according to claim 1, characterized in that, The elastic limiting mechanism includes a crossbar (8), which is fixedly installed inside the liquid guide tube (4). An inner tube (9) is fixedly sleeved on the wall of the crossbar (8). An outer tube (10) is slidably sleeved on the outside of the inner tube (9). A connecting plate (11) is fixedly installed at the bottom of the outer tube (10). The connecting plate (11) is fixedly connected to the sealing block (7). A spring (12) is fixedly installed between the inner walls of the outer tube (10) and the inner tube (9).

3. The automated integrated device for separating leukocytes according to claim 2, characterized in that, The outer tube (10) is fixedly provided with a sealing ring (13) at its opening, and the sealing ring (13) is sleeved on the outside of the inner tube (9).

4. The automated integrated device for separating leukocytes according to claim 1, characterized in that, The upper end of the outer wall of the separation dish (2) is threaded and threaded inside the dish cover (5).

5. The automated integrated device for separating leukocytes according to claim 1, characterized in that, A control motor (14) is fixedly installed on the top of the support frame (1). The output shaft end of the control motor (14) passes through the support frame (1) and is fixedly provided with a drive gear (15). A transmission gear (16) is fixedly sleeved on the outer wall of the vertical tube (3). The drive gear (15) and the transmission gear (16) are configured to cooperate.

6. The automated integrated device for separating leukocytes according to claim 1, characterized in that, The lower end of the inner wall of the vertical tube (3) is rotatably contacted by a sealing plate (17). The side of the vertical tube (3) is rotatably connected by a rotating rod (18). The end of the rotating rod (18) is inserted into the vertical tube (3) and fixedly connected to the sealing plate (17). The outer wall of the vertical tube (3) is fixedly fitted with a damping sleeve (19). The rotating rod (18) is rotatably inserted into the damping sleeve (19). The end of the rotating rod (18) is fixedly provided with a knob (20).

7. The automated integrated device for separating leukocytes according to claim 1, characterized in that, The support frame (1) has elastic telescopic rods (21) fixed on both sides of its inner wall. The end of the elastic telescopic rod (21) is fixed with a guide plate (22). The inner wall of the guide plate (22) is rolled with a plurality of spaced balls (23).

8. The automated integrated device for separating leukocytes according to claim 1, characterized in that, The outer wall of the separation dish (2) is fixed with two symmetrically arranged push blocks (24).

9. The automated integrated device for separating leukocytes according to claim 1, characterized in that, The liquid guide tube (4) is a flexible tube.

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