Cell electrotransduction instrument with dustproof mechanism for gene editing
By introducing a dust extraction system and an automatic opening and closing structure with a limiting slide bar into the cell electroporator, the problem of dust entering the device is solved, achieving an effective dust prevention effect and ensuring the long-term cleanliness of the device.
Patent Information
- Application Number
- CN202423003449.1
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-12-06
- Publication Date
- 2025-11-25
- Estimated Expiration
- 2034-12-06
AI Technical Summary
Existing cell electroporation instruments for gene editing allow dust to easily enter the device when the protective structure is opened and closed, resulting in poor dust protection and a lack of dust collection mechanism, which affects long-term performance.
A cell electroporation apparatus with a dustproof mechanism was designed, including a dust collection frame, a dust collection pipe, a dust collection box, and an air pump. The opening is automatically controlled and closed by the cooperation of a pull-out glass plate and a limiting slide bar, and the air pump is used to suck dust into the dust collection mesh frame for filtration and cleaning.
This effectively improves the dustproof performance of the cell electroporation instrument, ensuring that dust does not enter the device during opening and closing, achieving long-term dustproof treatment and improving the reliability of the device.
Smart Images

Figure CN223592730U_ABST
Abstract
Description
TECHNICAL FIELD
[0001] The utility model relates to a cell electrotransformation instrument with dustproof mechanism for gene editing belongs to cell electrotransformation instrument technical field. BACKGROUND
[0002] Gene editing, also known as genome editing or genome engineering, is a new and relatively precise gene engineering technology that can modify specific target genes in the genome of an organism. In the process of gene editing engineering technology detection, cell electrotransformation instrument is used by the staff. Through electroporation technology, DNA can be transferred into competent bacteria, plant and animal cells, and yeast cells.
[0003] The existing patent number CN219772137U cell electrotransformation instrument with dustproof mechanism for gene editing, the cooperation of the protective frame and the transparent glass plate in the dustproof mechanism can provide dustproof effect for the position of the detection platform, which can avoid the risk of infection of cell genes during the process of electrotransformation, improve the protection effect of cell genes, and the fixing seat in the positioning mechanism can provide the installation space of the clamping rod, so that the user can move the movable rod to drive the clamping rod and the fixed block installed on the protective frame to be clamped and fixed, and the protective frame can be positioned, and then the spring provides elastic action to avoid separation between the clamping rod and the fixed block. However, the opening and closing angle of the protective frame and the transparent glass plate in this device is too large, which makes the dust in the air enter the device, and some air is covered in the device during the opening and closing process, so that the dust in the device falls into the detection platform after the anti-skid frame and the transparent glass plate are closed, reducing the dustproof effect of the cell electrotransformation instrument. Moreover, this device does not have a dust collection mechanism, so that dust is continuously carried in the air, and no matter how the protective structure is protected, dust will enter the device when the protective structure is opened, which is not conducive to the long-term dustproof use of the cell electrotransformation instrument. UTILITY MODEL CONTENT
[0004] The utility model aims at providing a cell electrotransformation instrument with dustproof mechanism for gene editing to solve the problems in the above background technology.
[0005] To achieve the above purpose, the utility model provides the following technical scheme:
[0006] The utility model provides a cell electroporator with dustproof mechanism for gene editing, including cell electroporator main part, guard frame and electric conversion batten, the right front side of cell electroporator main part is fixedly connected with guard frame, the inside upper side of guard frame is slidably connected with pull -out glass board, the front end of pull -out glass board is fixedly connected with sealing end cap, the rear end left and right sides of sealing end cap are fixedly connected with limit slide rod, and the limit slide rod is slidably connected with guard frame, the surface of limit slide rod is covered with spring, the upper end outside of guard frame is fixedly connected with dust collection frame, the rear end of dust collection frame is sealedly connected with dust collection pipe, the rear end of dust collection pipe is sealedly connected with dust collection box, and the dust collection box is fixedly connected with cell electroporator main part, the right end upper side of dust collection box is sealedly connected with air pump.
[0007] Further, the inside lower side of the guard frame is provided with an electric conversion batten.
[0008] Further, the rear end of the limit slide rod is fixedly connected with a limit plate, the limit plate is slidably connected with the guard frame, and the inside upper side of the left and right side walls of the guard frame is provided with a circular insertion hole.
[0009] Further, the left and right sides of the pull-out glass board are fixedly connected with limit convex strips, the limit convex strips are slidably connected with the guard frame, the inside upper side of the front end wall of the guard frame is provided with a glass board rail groove, the rear side upper end of the front end wall of the guard frame is fixedly connected with a cleaning scraping strip, and the cleaning scraping strip is slidably connected with the pull-out glass board.
[0010] Further, the front end of the sealing end cap is fixedly connected with a pulling handle.
[0011] Further, the inside of the dust collection frame is sealedly connected with a dust collection end, and the dust collection end is sealedly connected with the dust collection pipe.
[0012] Further, the upper end of the dust collection box is spirally connected with a spiral cover, the lower end of the spiral cover is fixedly connected with a dust collection mesh frame, the front end upper side of the dust collection mesh frame is provided with a dust inlet, and the position and size of the dust inlet correspond to the rear end port position of the dust collection pipe.
[0013] The utility model has the advantages of:
[0014] The utility model discloses a limit protruding strip's effect makes the pull -out glass board can be in the inside front -and-back sliding of protection frame, and through the pull of pull handle makes the sealing end cover can drive the pull -out glass board moves back and forth, and can according to the opening of different size that needs to open, and make the limit slide bar can be in the round jack inside front -and-back sliding, further make the spring that sets up can compress, thereby make the device can control the size of the opening of taking and placing in the process of the retracting of electric conversion board, and can make the pull -out glass board can move to the rear side automatically after the pull handle is loosened, and the opening of retracting is automatically closed, promote the dustproof effect of electric conversion board, the utility model discloses the suction effect of air pump makes the dust suction end head can carry out the air exhaust, and make the gas carrying dust into the dust suction pipe, and make the gas carrying dust into the dust collection net frame, thereby make the gas of suction exhaust, and the dust that absorbs can be filtered in the dust collection net frame, further can carry out the dust removal treatment to the space where cell electric conversion instrument is located, and through the dismounting of screw cover, the dust collection net frame can be taken out, further can carry out the centralized cleaning of the dust of collection, promote the long -term use dustproof effect of cell electric conversion instrument. BRIEF DESCRIPTION OF DRAWINGS
[0015] The drawings are used to provide further understanding of the utility model and constitute a part of the specification, and are used to explain the utility model together with the specific implementation mode of the utility model, and do not constitute the limitation to the utility model.
[0016] Figure 1 It is the front view of a cell electric conversion instrument with dustproof mechanism for gene editing of the utility model;
[0017] Figure 2 It is the installation structure overhead view of pull -out glass board and sealing end cover of a cell electric conversion instrument with dustproof mechanism for gene editing of the utility model;
[0018] Figure 3 It is the installation structure back section view of protection frame of a cell electric conversion instrument with dustproof mechanism for gene editing of the utility model;
[0019] Figure 4 It is the installation structure right section view of dust suction frame, dust suction pipe and dust collection box of a cell electric conversion instrument with dustproof mechanism for gene editing of the utility model;
[0020] Marked number in drawing: 1, cell electric conversion instrument main part;2, protection frame;3, pull -out glass board;4, sealing end cover;5, limit slide bar;6, spring;7, dust suction frame;8, dust suction pipe;9, dust collection box;10, air pump;11, electric conversion board;12, limit board;13, round jack;14, limit protruding strip;15, glass board rail groove;16, cleaning scraping strip;17, pull handle;18, dust suction end head;19, screw cover;20, dust collection net frame. DETAILED DESCRIPTION
[0021] The technical solutions in the embodiments of the utility model will be clearly and completely described below with reference to the drawings in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, rather than all the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by those skilled in the art without creative labor fall within the scope of protection of the utility model.
[0022] Embodiment 1 Please refer to Figures 1-4 The utility model provides a technical scheme:
[0023] A cell electroporator for gene editing with dustproof mechanism, including cell electroporator main part 1, guard frame 2 and electric conversion batten 11, cell electroporator main part 1's right front side is fixedly connected with guard frame 2, the inside upper side of guard frame 2 is slidably connected with pull-out glass plate 3, the front end of pull-out glass plate 3 is fixedly connected with sealing end cap 4, the rear end of sealing end cap 4 is fixedly connected with limiting slide rod 5 on both sides, limiting slide rod 5 is slidably connected between guard frame 2, the surface of limiting slide rod 5 is covered with spring 6, the inside lower side of guard frame 2 is equipped with electric conversion batten 11, the rear end of limiting slide rod 5 is fixedly connected with limiting plate 12, limiting plate 12 is slidably connected between guard frame 2, the inside upper side of the left and right side walls of guard frame 2 is all set with round jack 13, the left and right sides of pull-out glass plate 3 are all fixedly connected with limiting convex strip 14, limiting convex strip 14 is slidably connected between guard frame 2, the inside upper side of the front end wall of guard frame 2 is set with glass plate rail groove 15, the upper end of the rear side of the front end wall of guard frame 2 is fixedly connected with cleaning scraping strip 16, cleaning scraping strip 16 is slidably connected between pull-out glass plate 3, the front end of sealing end cap 4 is fixedly connected with pull handle 17, the effect that limiting convex strip 14 is set makes pull-out glass plate 3 can be in the inside front and back sliding of guard frame 2, and by the pulling of pull handle 17 makes sealing end cap 4 can drive pull-out glass plate 3 moves back and forth, and can according to the required opening of different size, and make limiting slide rod 5 can be in the front and back sliding of round jack 13, further make the setting spring 6 can compress, so that the device can control the size of the opening of the taking and placing mouth during the retraction of electric conversion batten 11, and can make pull-out glass plate 3 can move to the rear side automatically after the pull handle 17 is loosened, the automatic closing processing of the retraction opening is carried out, the dustproof processing effect of electric conversion batten 11 is improved.
[0024] Embodiment 2 Please refer to Figure 1 And Figure 4The embodiment is different from embodiment 1 in that the upper end outer side of the protection frame 2 is fixedly connected with a dust suction frame 7, the rear end of the dust suction frame 7 is sealingly connected with a dust suction pipe 8, the rear end of the dust suction pipe 8 is sealingly connected with a dust collection box 9, the dust collection box 9 is fixedly connected with the cell electroporator main body 1, the right end upper side of the dust collection box 9 is sealingly connected with an air pump 10, the inside of the dust suction frame 7 is sealingly connected with a dust suction end head 18, the dust suction end head 18 is sealingly connected with the dust suction pipe 8, the upper end of the dust collection box 9 is screw-connected with a screw cover 19, the lower end of the screw cover 19 is fixedly connected with a dust collection screen frame 20, the front end upper side of the dust collection screen frame 20 is provided with a dust inlet, the position and size of the dust inlet correspond to the rear end port position of the dust suction pipe 8, the suction of the dust suction end head 18 is realized by the suction of the air pump 10, the gas carrying dust enters the dust suction pipe 8, and then the gas carrying dust enters the dust collection screen frame 20, so that the suction gas is discharged, and the absorbed dust is filtered in the dust collection screen frame 20, thereby realizing the dust removal treatment of the space where the cell electroporator is located, the dust collection screen frame 20 can be taken out by detaching the screw cover 19, thereby realizing the centralized cleaning and discharging treatment of the collected dust, and the long-term use dustproof effect of the cell electroporator is improved.
[0025] The working principle of the utility model is: when the device is used, the pulling glass plate 3 can slide in the protection frame 2 by the action of the limiting convex strip 14, the sealing end cover 4 can drive the pulling glass plate 3 to move forward and backward by pulling the pulling handle 17, different size openings can be opened according to the requirement, the limiting slide rod 5 can slide in the round insertion hole 13, the spring 6 can be compressed, thereby the device can control the size of the opening during the taking and placing of the electric conversion plate strip 11, the pulling glass plate 3 can automatically move to the rear side after the pulling handle 17 is loosened, the taking and placing opening is automatically closed, the dustproof effect of the electric conversion plate strip 11 is improved, the suction of the dust suction end head 18 is realized by the suction of the air pump 10, the gas carrying dust enters the dust suction pipe 8, and then the gas carrying dust enters the dust collection screen frame 20, so that the suction gas is discharged, and the absorbed dust is filtered in the dust collection screen frame 20, thereby realizing the dust removal treatment of the space where the cell electroporator is located, the dust collection screen frame 20 can be taken out by detaching the screw cover 19, thereby realizing the centralized cleaning and discharging treatment of the collected dust, and the long-term use dustproof effect of the cell electroporator is improved.
[0026] Although the embodiments of the utility model have been shown and described, it can be understood by those skilled in the art that various changes, modifications, replacements and variations can be made to these embodiments without departing from the principles and spirits of the utility model, the scope of the utility model is defined by the appended claims and their equivalents.
Claims
1. A cell electroporator with dustproof mechanism for gene editing, comprising a cell electroporator main body (1), a protective frame (2) and an electroporation plate strip (11), characterized in that: The right front side of the cell electroporator body (1) is fixedly connected with a protective frame (2), the inner upper side of the protective frame (2) is slidably connected with a pull-out glass plate (3), the front end of the pull-out glass plate (3) is fixedly connected with a sealing end cover (4), the rear end of the sealing end cover (4) is fixedly connected with a limiting slide rod (5) on the left and right sides, the limiting slide rod (5) is slidably connected with the protective frame (2), the surface of the limiting slide rod (5) is covered with a spring (6), the upper end of the outer side of the protective frame (2) is fixedly connected with a dust collection frame (7), the rear end of the dust collection frame (7) is sealingly connected with a dust collection pipe (8), the rear end of the dust collection pipe (8) is sealingly connected with a dust collection box (9), the dust collection box (9) is fixedly connected with the cell electroporator body (1), and the right end of the upper side of the dust collection box (9) is sealingly connected with an air pump (10).
2. The cell electroporator with dustproof mechanism for gene editing according to claim 1, characterized in that: The inner lower side of the protective frame (2) is provided with an electroporation plate strip (11).
3. The cell electroporator with dustproof mechanism for gene editing according to claim 1, characterized in that: The rear end of the limiting slide rod (5) is fixedly connected with a limiting plate (12), the limiting plate (12) is slidably connected with the protective frame (2), and the inner upper sides of the left and right side walls of the protective frame (2) are both provided with a circular jack (13).
4. The cell electroporator with dustproof mechanism for gene editing according to claim 1, characterized in that: The left and right sides of the pull-out glass plate (3) are both fixedly connected with a limiting convex strip (14), the limiting convex strip (14) is slidably connected with the protective frame (2), the inner upper side of the front end wall of the protective frame (2) is provided with a glass plate rail groove (15), the rear side of the upper end of the front end wall of the protective frame (2) is fixedly connected with a cleaning scraping strip (16), and the cleaning scraping strip (16) is slidably connected with the pull-out glass plate (3).
5. The cell electroporator with dustproof mechanism for gene editing according to claim 1, characterized in that: The front end of the sealing end cover (4) is fixedly connected with a pulling handle (17).
6. The cell electroporator with dustproof mechanism for gene editing according to claim 1, characterized in that: The inner side of the dust collection frame (7) is sealingly connected with a dust collection end (18), and the dust collection end (18) is sealingly connected with the dust collection pipe (8).
7. The cell electroporator with dustproof mechanism for gene editing according to claim 1, characterized in that: The upper end of the dust collection box (9) is spirally connected with a spiral cover (19), the lower end of the spiral cover (19) is fixedly connected with a dust collection mesh frame (20), the front end of the dust collection mesh frame (20) is provided with a dust inlet on the upper side, and the position and size of the dust inlet correspond to the rear end port of the dust collection pipe (8).
Citation Information
Patent Citations
Cell electrotransduction instrument with dustproof mechanism for gene editing
CN219772137U