Organ-like chromatographic separation device

Abstract

The utility model discloses an organ-like chromatographic separation device, which relates to the technical field of medical instruments, and comprises a support frame and a connecting frame fixedly connected to the top of the support frame, the top of the support frame is also fixedly connected with a servo motor, the support frame is provided with a placing structure, and the placing structure is used for simultaneously carrying out separation operation on a plurality of groups of separators. The placing structure comprises a first limiting block fixedly connected to the output end of the servo motor, a rotating frame is detachably arranged on the top of the connecting frame, and a connecting plate is further detachably arranged on the top of the connecting frame. Through the arrangement of the placing groove II, the separation pipes and the rotating frame, the effect of simultaneously carrying out separation operation on multiple groups of primary separation pipes is realized, the working efficiency is improved, and the problems that most of existing chromatographic separation devices are single in structure, multiple groups of separators are often inconvenient to carry out separation operation simultaneously in the use process, and the use cost is high are solved. And only a single separator can be subjected to separation operation, so that the working efficiency is greatly influenced.

Description

TECHNICAL FIELD

[0001] The utility model relates to medical instrument technical field, concretely is a kind of organoid chromatography separation device. BACKGROUND

[0002] Chromatography is the technology established by the difference of the physical and chemical properties of different substances. When the mixture to be separated passes through the stationary phase with the mobile phase, due to the difference in physical and chemical properties of each component, the ability of interaction with the two phases is different, the distribution in the two phases is different, and the mobile phase moves forward, each component continuously redistributes in the two phases. Collecting the effluent can obtain each single component contained in the sample, so as to separate each component. However, the existing chromatography separation device still has some problems in actual use.

[0003] For example, application No. CN202122690947.8 discloses a novel organoid chromatography separation device, which includes a top pipe, a middle pipe and a bottom pipe. The top pipe and the middle pipe are threadedly connected, and the middle pipe and the bottom pipe are threadedly connected. A filter plate is installed inside the top pipe to filter organoid cells larger than cubic millimeters. A filter membrane is installed inside the middle pipe to separate and process the cell liquid. The existing chromatography separation device has a single structure, and it is not convenient to separate multiple separators simultaneously during use. Only single separators can be separated, which greatly affects the work efficiency.

[0004] To solve the above problems, an organoid chromatography separation device is proposed. UTILITY MODEL CONTENTS

[0005] The utility model aims to provide an organoid chromatography separation device. The device can solve the problem of single structure of the existing chromatography separation device, which makes it inconvenient to separate multiple separators simultaneously during use. Only single separators can be separated, which greatly affects the work efficiency.

[0006] To achieve the above purpose, the utility model provides the following technical scheme: an organoid chromatography separation device includes a support frame and a connecting frame fixedly connected to the top of the support frame. The top of the support frame is also fixedly connected to a servo motor. The support frame is provided with a placing structure for simultaneously separating multiple separators. The placing structure includes a limiting block one fixedly connected to the output end of the servo motor. The top of the connecting frame is detachably provided with a rotating frame. The top of the connecting frame is also detachably provided with a connecting plate. The rotating frame is provided with multiple placing grooves two.

[0007] Preferably, the top end of the connecting frame is provided with a placing groove one, and the connecting frame is provided with two groups of placing grooves one.

[0008] The above structure is adopted, the connecting frame is arranged, the related device can be placed on the connecting frame, and the space utilization of the device is improved.

[0009] Preferably, the bottom of the connecting plate is fixedly connected with a placing block, the placing block is provided with two groups, the placing block and the placing groove one are in sliding fit, and the side of the placing block is provided with a threaded groove one.

[0010] The above structure is adopted, the placing block and the placing groove one are arranged, the mounting process of the connecting plate becomes more convenient, and the use efficiency is improved.

[0011] Preferably, the threaded groove one is in threaded fit with the screw, the top of the rotating frame is fixedly connected with a limiting block three, and the bottom of the connecting plate is further rotatably connected with a limiting block two.

[0012] The above structure is adopted, the limiting block three is arranged, the rotating frame can be stably connected with the servo motor, and the stability is improved.

[0013] Preferably, the limiting block two and the limiting block three are in sliding fit, the bottom of the rotating frame is fixedly connected with a limiting block four, and the limiting block four and the limiting block one are in sliding fit.

[0014] The above structure is adopted, the limiting block four and the limiting block one are arranged, the connecting stability of the rotating frame is further improved, and subsequent separation operation is facilitated.

[0015] Preferably, the inside of the placing groove two is detachably provided with a first separation pipe, the top of the first separation pipe is detachably provided with a second separation pipe, and the inside of the first separation pipe is fixedly connected with a filter membrane.

[0016] The above structure is adopted, the filter membrane is arranged, the device can more conveniently separate the organoid tissue into two different sizes.

[0017] Preferably, one end of the first separation pipe and one end of the second separation pipe are provided with a threaded groove two, and the two groups of threaded grooves two are in threaded fit.

[0018] The above structure is adopted, the threaded groove two is arranged, the dismounting operation of the first separation pipe and the second separation pipe becomes more rapid, and the convenience is improved.

[0019] Compared with the prior art, the device has the beneficial effects as follows:

[0020] 1、The application realizes the function of simultaneously separating multiple groups of primary separation tubes, improves work efficiency, and solves the problem of single structure of the existing chromatographic separation device, which is inconvenient to simultaneously separate multiple groups of separators during use and can only separate a single separator, greatly affecting work efficiency.

[0021] 2、The application realizes the function of chromatographic separation of organoids through automatic control device, solves the problem of manual shaking during separation operation of the existing chromatographic separation device, and is not conducive to use. DRAWINGS

[0022] Figure 1 It is a schematic diagram of the overall structure of the utility model;

[0023] Figure 2 It is a structure diagram of the connecting frame and connecting plate of the utility model;

[0024] Figure 3 It is a structure diagram of the rotating frame and the placement slot two of the utility model;

[0025] Figure 4 It is another perspective structure diagram of the rotating frame of the utility model;

[0026] Figure 5 It is a structure diagram of the primary separation tube and the secondary separation tube of the utility model.

[0027] In the figure: 1, support frame; 11, connecting frame; 111, servo motor; 112, limit block one; 12, rotating frame; 121, connecting plate; 122, placement slot one; 123, screw; 124, placement block; 125, thread groove one; 126, limit block two; 13, placement slot two; 131, limit block three; 132, limit block four; 14, primary separation tube; 141, secondary separation tube; 142, filter membrane; 143, thread groove two. DETAILED DESCRIPTION

[0028] The technical solutions in the embodiments of the utility model will be described clearly and completely in combination with the drawings in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by those skilled in the art without creative labor belong to the scope of protection of the utility model.

[0029] In order to further understand the content of the utility model, the utility model will be described in detail in combination with the drawings.

[0030] In combination Figures 1-4 An organ-like layer separation device, comprising a support frame 1 and a connecting frame 11 fixedly connected to the top of the support frame 1, and a servo motor 111 fixedly connected to the top of the support frame 1, and the support frame 1 is provided with a placing structure for simultaneously separating a plurality of separators, the placing structure comprises a limiting block one 112 fixedly connected to the output end of the servo motor 111, the top of the connecting frame 11 is detachably provided with a rotating frame 12, and the top of the connecting frame 11 is also detachably provided with a connecting plate 121, the rotating frame 12 is provided with a plurality of placing grooves two 13.

[0031] The utility model will be further described below in combination with the embodiments.

[0032] Embodiment 1:

[0033] To solve the problem that most of the existing layer separation devices have single structure, and it is inconvenient to simultaneously separate a plurality of separators during use, and only a single separator can be separated, which greatly affects the work efficiency, the following scheme is disclosed, and specific reference can be made to Figures 1-5The top end of the connecting frame 11 is provided with a placing groove one 122, and the placing groove one 122 is provided with two groups. The side of the connecting frame 11 is threadedly connected with a screw 123. The bottom of the connecting plate 121 is fixedly connected with a placing block 124, and the placing block 124 is provided with two groups. The placing block 124 and the placing groove one 122 are in sliding fit. The side of the placing block 124 is provided with a threaded groove one 125, and the threaded groove one 125 is in threaded fit with the screw 123. The top of the rotating frame 12 is fixedly connected with a limiting block three 131. The bottom of the connecting plate 121 is also rotatably connected with a limiting block two 126. The limiting block two 126 and the limiting block three 131 are in sliding fit. The bottom of the rotating frame 12 is fixedly connected with a limiting block four 132, and the limiting block four 132 and the limiting block one 112 are in sliding fit. The inside of the placing groove two 13 is detachably provided with a primary separation pipe 14. The top of the primary separation pipe 14 is detachably provided with a secondary separation pipe 141. The inside of the primary separation pipe 14 is fixedly connected with a filter membrane 142. One end of the primary separation pipe 14 and one end of the secondary separation pipe 141 are provided with a threaded groove two 143, and the two groups of threaded groove two 143 are in threaded fit. When separation operation is needed, the liquid to be separated can be placed in the inside of the primary separation pipe 14. Then the secondary separation pipe 141 is twisted, so that the threaded groove two 143 on the primary separation pipe 14 and the secondary separation pipe 141 is completely tightened. Then the primary separation pipe 14 is placed in the inside of the placing groove two 13 on the rotating frame 12. At this time, the four groups of primary separation pipes 14 can be respectively placed in the inside of the corresponding placing groove two 13. Then the limiting block four 132 at the bottom of the rotating frame 12 is aligned with the limiting block one 112 and put in. Then the connecting plate 121 is placed on the top of the connecting frame 11, so that the placing block 124 at the bottom of the connecting plate 121 is placed in the inside of the placing groove one 122. At this time, the limiting block two 126 and the limiting block three 131 are fixed. Finally, the screw 123 is twisted, so that the placing block 124 is fixed in the inside of the placing groove one 122. When separation operation is needed, the servo motor 111 is started. The servo motor 111 drives the limiting block one 112 to rotate, so that the rotating frame 12 rotates. The rotating frame 12 drives the multiple groups of primary separation pipes 14 to rotate. At this time, the filter membrane 142 in the inside of the primary separation pipe 14 is arranged, so that the separation operation in the inside of the primary separation pipe 14 is completed. The organoid tissue is separated into two different sizes. The function that multiple groups of primary separation pipes 14 can be simultaneously separated is realized, and the working efficiency is improved.

[0034] It is to be noted that, in the present document, relational terms such as first and second and the like can be used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions. Moreover, the terms "comprises", "comprising", or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but can include other elements not expressly listed or inherent to such process, method, article, or apparatus.

[0035] While the embodiments of the present application have been illustrated and described, it will be understood by those skilled in the art that various changes, modifications, substitutions, and alterations can be made therein without departing from the spirit and scope of the application, which is defined by the appended claims and their equivalents.

Claims

1. An organoid layering device, comprising a support frame (1) and a connecting frame (11) fixedly connected to the top of the support frame (1), characterized in that: The top of the support frame (1) is also fixedly connected with a servo motor (111), the support frame (1) is provided with a placing structure, the placing structure is used for simultaneously separating a plurality of groups of separators, the placing structure comprises a limiting block one (112) fixedly connected to the output end of the servo motor (111), the top of the connecting frame (11) is detachably provided with a rotating frame (12), and the top of the connecting frame (11) is also detachably provided with a connecting plate (121).

2. An organoid layering device according to claim 1, wherein: The top of the connecting frame (11) is provided with a placing groove one (122), and the placing groove one (122) is provided with two groups.

3. An organoid layering device according to claim 2, wherein: The bottom of the connecting plate (121) is fixedly connected with a placing block (124), and the placing block (124) is provided with two groups.

4. An organoid layering device according to claim 3, wherein: The bottom of the connecting plate (121) is also rotatably connected with a limiting block two (126).

5. An organoid layering device according to claim 4, wherein: The limiting block two (126) and the limiting block three (131) are in sliding fit.

6. An organoid layering device according to claim 5, wherein: The bottom of the rotating frame (12) is fixedly connected with a limiting block four (132), and the limiting block four (132) is in sliding fit with the limiting block one (112).

7. An organoid layering device according to claim 6, wherein: The inside of the placing groove two (13) is detachably provided with a primary separation pipe (14), the top of the primary separation pipe (14) is detachably provided with a secondary separation pipe (141), and the inside of the primary separation pipe (14) is fixedly connected with a filter membrane (142). One end of the primary separation pipe (14) and one end of the secondary separation pipe (141) are provided with a threaded groove two (143), and the two groups of threaded grooves two (143) are in threaded fit.

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