Nitrogen charging device and product production line
By using nitrogen-filling modules of different effective lengths and optimizing the design of the vent holes on the pharmaceutical production line, the problems of insufficient residual oxygen and poor consistency in the pharmaceutical containers were solved, achieving efficient gas replacement and consistency in the pharmaceutical containers.
Patent Information
- Application Number
- CN202423281839.5
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-12-30
- Publication Date
- 2025-11-28
- Estimated Expiration
- 2034-12-30
AI Technical Summary
In existing technologies, during the production process of pharmaceutical containers, the residual oxygen content is not up to standard and the consistency is poor. In particular, the gas replacement time and effect of pharmaceutical containers of different volumes in the nitrogen filling device are uneven, resulting in problems with the content and consistency of the pharmaceuticals.
At least two sets of nitrogen-filling modules with different effective lengths are used in combination. The appropriate nitrogen-filling module is selected according to the volume of the reagent container for gas replacement. By setting multiple nitrogen-filling modules, the gas replacement effect is ensured, and the gas outlet settings, including setting multiple gas outlets and diffusion chambers, are optimized to optimize the gas replacement process.
The residual oxygen content of reagent containers of different volumes has been made up to meet the standards and achieve consistency. By optimizing the design of the nitrogen filling module, the gas replacement effect inside the reagent container is ensured, and the loss of reagent content and consistency differences are reduced.
Smart Images
Figure CN223605851U_ABST
Abstract
Description
TECHNICAL FIELD
[0001] The utility model relates to medicine filling equipment technical field, more specifically, relate to a nitrogen filling device, in addition, the utility model relates to a product production assembly line comprising the nitrogen filling device. BACKGROUND
[0002] The medicine filling adopts the assembly line production, and in the production process, the consistency evaluation residual oxygen content of the sterile preparation is less than 2%, so it is necessary to arrange the nitrogen filling device in the assembly line to replace the air in the medicine container, thereby reducing the residual oxygen content in the product, and in the prior art, as shown in the figure, only a group of nitrogen filling device of fixed length is arranged in the assembly line, and the feeding speed of the assembly line is fixed, but the containers of different medicines are not equal, so the effective nitrogen filling time of different medicine containers in the nitrogen filling device is the same, and the volume of the replaced gas is close, which causes that the residual oxygen content of different volume medicine containers does not reach the standard and the consistency is poor. Figure 1
[0003] If the gas flow rate in the nitrogen filling device is adjusted to change the gas displacement amount in the medicine container in the same time, the powdery medicine in the medicine container will float and overflow due to the large gas flow rate, thereby reducing the content of the medicine and deteriorating the consistency.
[0004] In summary, how to solve the problem that the internal residual oxygen content of different medicine containers does not reach the standard and the consistency is poor during production is a problem to be solved by the technical personnel in the field. UTILITY MODEL CONTENT
[0005] Therefore, the utility model aims at providing a nitrogen filling device, which is combined with at least two groups of nitrogen filling modules with different effective lengths to meet the displacement demand of the gas in the product container of different volume, thereby ensuring that the residual oxygen content and consistency in the product reach the standard.
[0006] Another object of the utility model is to provide a product production assembly line comprising the above-mentioned nitrogen filling device, which has the same technical scheme and can solve the same technical problem.
[0007] In order to achieve the above object, the utility model provides the following technical scheme:
[0008] A nitrogen filling device is arranged on the conveying belt of the product production assembly line to replace the gas in the product container, comprising a plurality of groups of nitrogen filling modules, the nitrogen filling module comprises a closed gas cavity, the gas cavity is provided with a gas inlet and a gas outlet, and the gas inlet is communicated with the gas source main line;
[0009] At least two groups of the nitrogen filling modules are arranged along the feeding direction of the conveying belt, and the effective working lengths of the two groups of nitrogen filling modules are different.
[0010] The gas outlet hole of the nitrogen filling module is arranged along the feeding direction of the conveying belt, and the opening direction of the gas outlet hole is arranged opposite to the opening direction of the product container, so that the gas flow in the gas cavity can be sprayed into the product container through the gas outlet hole.
[0011] Preferably, the nitrogen filling module further comprises a top-closed diffusion cavity for the product container to pass through from the inside, and the gas outlet hole is arranged at the top of the diffusion cavity.
[0012] Preferably, vertical guard plates are arranged on both sides of the diffusion cavity along the feeding direction of the gas container, for delaying the diffusion speed of the gas in the diffusion cavity.
[0013] Preferably, a plurality of groups of gas outlet holes with different diameters are arranged in the same nitrogen filling module, the gas outlet holes with the smallest diameter are arranged at equal intervals, and a fixed number of gas outlet holes with other diameters are arranged between the two adjacent groups of gas outlet holes with the smallest diameter.
[0014] Preferably, the spacing between the two adjacent groups of gas outlet holes with the smallest diameter is equal to the spacing of the product containers in the conveying belt.
[0015] Preferably, at least one group of the nitrogen filling modules is in an arc-shaped structure, arranged around the compression disc in the conveying belt.
[0016] The gas outlet hole is in a strip-shaped structure arranged along the feeding direction of the product container, the center line of the gas outlet hole and the center line of the opening of the product container in the conveying belt form an angle, and the opening of the product container is within the exhaust coverage range of the gas outlet hole.
[0017] Preferably, the gas inlets of all the nitrogen filling modules are connected in parallel with the gas source main line, and a flow controller is connected in series in the gas source main line.
[0018] Preferably, at least two levels of sterilization filters are connected in series in the gas source main line, for sterilization filtering of the gas flow in the gas source main line.
[0019] A product production line comprising the nitrogen filling device.
[0020] Compared with the prior art, the nitrogen filling device has at least the following beneficial effects:
[0021] 1. By arranging at least two groups of nitrogen filling modules with different effective lengths, and selecting appropriate effective length of the nitrogen filling module according to the volume of the product container, or using a plurality of groups of nitrogen filling modules with different effective lengths in combination, the residual oxygen content and consistency of the product can be ensured to meet the standard.
[0022] 2. The outlet holes in at least two groups of nitrogen charging modules are arranged opposite to the opening direction of the product container, so that the gas in the gas cavity can be directly injected into the product container through the outlet holes, thereby rapidly replacing the original gas in the product container, and reducing the residual oxygen content in the product container.
[0023] The product production line provided by the utility model has the same beneficial effects as the nitrogen charging device. BRIEF DESCRIPTION OF DRAWINGS
[0024] In order to more clearly illustrate the technical scheme in the embodiments of the utility model or the prior art, the drawings needed to be used in the embodiment or the prior art description will be briefly introduced below, and obviously, the drawings in the following description are only the embodiments of the utility model, and for those skilled in the art, other drawings can be obtained according to the provided drawings without creative labor.
[0025] Figure 1 It is the design scheme schematic diagram in the prior art;
[0026] Figure 2 It is the structure schematic diagram of the specific nitrogen charging device provided by the utility model;
[0027] Figure 3 It is the transverse section schematic diagram of the specific nitrogen charging module provided by the utility model;
[0028] Figure 4 It is the longitudinal section schematic diagram of the specific nitrogen charging module provided by the utility model;
[0029] Figure 5 It is the transverse section schematic diagram of the specific nitrogen charging module of the arc structure provided by the utility model;
[0030] Figure 6 It is the plan view of the specific nitrogen charging module of the arc structure provided by the utility model.
[0031] In the drawings:
[0032] 1. First nitrogen charging module;11. Gas cavity;12. Diffusion cavity;13. First outlet hole;14. Guard plate;15. First gas inlet;
[0033] 2. Second nitrogen charging module;
[0034] 3. Third nitrogen charging module;31. Second outlet hole;32. Second gas inlet;
[0035] 4. Flow controller;5. Sterilization filter;6. Plug rotary disc. DETAILED DESCRIPTION
[0036] The technical solutions in the embodiments of the utility model will be clearly and completely described below with reference to the drawings in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, rather than all the embodiments. Based on the embodiments of the utility model, all other embodiments obtained by those skilled in the art without creative labor fall within the scope of the utility model.
[0037] The core of the utility model provides a kind of nitrogen filling device, by at least two groups of nitrogen filling module with different effective length combination use, meet the replacement demand of different volume product container gas, to ensure that product residual oxygen content and consistency meet standard.
[0038] Another core of the utility model provides a kind of product production line including the above-mentioned nitrogen filling device, with identical technical solutions, can solve identical technical problems.
[0039] Please refer to Figures 2-6 A kind of nitrogen filling device, for the transmission belt of product production line, to replace the gas in product container, including several groups of nitrogen filling module, nitrogen filling module includes closed gas cavity 11, gas cavity 11 is provided with gas inlet and gas hole, gas inlet is communicated with gas source main road;
[0040] At least two groups of nitrogen filling module are arranged along the feeding direction of transmission belt, and the effective working length of two groups of nitrogen filling module is different;
[0041] The gas hole of nitrogen filling module is arranged along the feeding direction of transmission belt, and the opening direction of gas hole is oppositely arranged with the opening direction of product container, so that the airflow in gas cavity 11 can be injected into product container through gas hole;
[0042] As Figure 2 As shown in the figure, at least two groups of nitrogen filling module are arranged on the transmission belt, which are first nitrogen filling module 1 and second nitrogen filling module 2, the effective working length of first nitrogen filling module 1 is greater than that of second nitrogen filling module 2, that is, the time of product container staying and gas replacement in first nitrogen filling module 1 is greater than that in second nitrogen filling module 2;
[0043] Therefore, when small-volume product containers are filled, only second nitrogen filling module 2 needs to work, and gas replacement can meet the requirement of final residual oxygen content of product; when large-volume product containers are filled, only first nitrogen filling module 1 needs to work, and gas replacement can meet the requirement of final residual oxygen content of product; or when larger-volume product containers are filled, first nitrogen filling module 1 and second nitrogen filling module 2 are combined for use, and gas replacement is carried out simultaneously, which effectively prolongs the gas replacement time of product container, and further ensures that the gas in product container is completely replaced, thereby reducing the final residual oxygen content of product.
[0044] As shown in Figure 3 and Figure 4 , the first gas inlet 15 of the gas cavity 11 of the nitrogen filling module is communicated with the gas source main line, so that the nitrogen can quickly fill the gas cavity 11, and then be discharged from the first gas outlet hole 13, and the first gas outlet hole 13 is arranged opposite to the product container opening on the conveying belt, so that the nitrogen sprayed from the first gas outlet hole 13 can directly enter the product container to displace the original gas in the product container. In actual operation, the gas flow rate in the gas source main line needs to be kept constant, that is, the gas flow rate of the first gas inlet 15 needs to be kept constant, the exhaust gas flow rate of the first gas outlet hole 13 needs to be kept constant, and the gas flow rate of the first gas outlet hole 13 should be kept stable within a set range, so as to ensure that the nitrogen gas flow can be sprayed to the bottom of the product container and will not cause the powder product in the product container to float and overflow.
[0045] In some embodiments, the nitrogen filling module further comprises a top-closed diffusion cavity 12 for the product container to pass through from the inside thereof, and the gas outlet hole is arranged at the top of the diffusion cavity 12.
[0046] As shown in Figure 3 and Figure 4 , the first nitrogen filling module 1 and the second nitrogen filling module 2 further comprise a diffusion cavity 12, and the first gas outlet hole 13 is arranged at the top of the diffusion cavity 12, that is, the nitrogen gas flow is sprayed downward from the top, when the product container passes through the position directly opposite to the first gas outlet hole 13, the nitrogen gas flow can directly flow into the product container and displace the air in the product container, and the excess nitrogen can be simultaneously overflowed with the excess air in the product container. Since the density of nitrogen is less than that of air, the nitrogen floats up and the air sinks down. At this time, the excess nitrogen can be gathered in the diffusion cavity 12, and the air diffuses downward. When the concentration of nitrogen in the diffusion cavity 12 is relatively large, the upper layer of nitrogen can wrap the opening of the product container, effectively preventing the external air from entering the product container again.
[0047] In some embodiments, vertical guard plates 14 are arranged on both sides of the diffusion cavity 12 along the gas container feeding direction, for delaying the diffusion speed of the gas in the diffusion cavity 12.
[0048] As shown in Figure 3 , by arranging the vertical guard plates 14 on both sides of the diffusion cavity 12, more nitrogen can be stored in the diffusion cavity 12, so that more nitrogen can be gathered at the opening position of the product container, and by using the density difference between nitrogen and air, the air in the diffusion cavity 12 is discharged downward to be far away from the opening of the product container, further preventing the external air from entering through the opening position of the product container.
[0049] In some embodiments, a plurality of groups of gas outlets with different diameters are arranged in the same nitrogen filling module, the smallest diameter gas outlets are arranged at equal intervals, and a fixed number of gas outlets with other diameters are arranged between any two adjacent groups of smallest diameter gas outlets;
[0050] As shown in the drawings, Figure 4 A plurality of groups of first gas outlets 13 with different diameters are arranged along the feeding direction of the conveying belt at the top of the diffusion chamber 12. According to the law of fluid mechanics, the gas flow rate at the small-diameter first gas outlets 13 is greater than that at the large-diameter first gas outlets 13, and the gas flow at the small-diameter first gas outlets 13 has a longer jet distance, which can make the nitrogen gas flow quickly reach the bottom of the product container and quickly displace the air in the product container. At the same time, the nitrogen gas flow rate at the large-diameter first gas outlets 13 is slower, and the jet distance is shorter, mainly diffusing in the long layer of the diffusion chamber 12 to wrap the opening position of the product container and isolate the external air from entering. The different diameter first gas outlets 13 work together to quickly displace the air in the product container and effectively prevent external air from re-entering the product container.
[0051] In some embodiments, the spacing between any two adjacent groups of smallest diameter gas outlets is equal to the spacing of the product containers in the conveying belt;
[0052] As shown in the drawings, Figure 4 When arranging the first gas outlets 13, the spacing of the smallest diameter first gas outlets 13 is consistent with the spacing of the product containers on the conveying belt, so that the displaced air has the same overflow speed and direction and does not interfere with each other, thereby avoiding the effect of air displacement in adjacent product containers.
[0053] In some embodiments, at least one nitrogen filling module is in an arc shape for surrounding the pressing disc 6 in the conveying belt;
[0054] The gas outlet is a strip-shaped structure arranged along the feeding direction of the product container. The center line of the gas outlet and the center line of the opening of the product container in the conveying belt form an angle, and the opening of the product container is within the exhaust coverage range of the gas outlet;
[0055] As shown in the drawings, Figure 2 , Figure 5 and Figure 6 After the product container is completed gas displacement, it needs to be sealed, which mainly depends on the pressure applied by the top of the pressing disc 6. Therefore, the third nitrogen filling module 3 with an arc shape is more consistent with the movement trajectory of the product container in the pressing disc 6;
[0056] The second gas inlet 32 of the third nitrogen filling module 3 is also communicated with the main gas source line, and a strip-shaped second gas outlet hole 31 is arranged at the side of the third nitrogen filling module 3, nitrogen gas is directly sprayed and diffused at the opening of the product container, the gas in the product container is continuously isolated from the external gas, and the external gas is prevented from entering the product container, and in order to avoid the interference of the third nitrogen filling module 3 on the moving part in the plug-in rotating disc 6, the third nitrogen filling module 3 is placed at the side of the plug-in rotating disc 6, and the center line of the second gas outlet hole 31 and the center line of the product container form an angle, as shown in Figure 5 The center line of the second gas outlet hole 31 is perpendicular to the center line of the product container, and the opening of the product container is in the exhaust coverage range of the second gas outlet hole 31.
[0057] In some embodiments, the gas inlets of all the nitrogen filling modules are communicated with the main gas source line in parallel, and the flow controller 4 is connected in series in the main gas source line;
[0058] As shown in Figure 2 The first nitrogen filling module 1, the second nitrogen filling module 2 and the third nitrogen filling module 3 are connected with the main gas source line in parallel, that is, the gas flow entering the three is the same, that is, the gas flow in the main gas source line is constant speed, which can ensure that the gas flow in the three is constant speed, and then the flow controller 4 is added in the main gas source line, which can adjust the flow rate while ensuring the constant speed of the gas flow in the main gas source line, and further meet the operation requirements of air replacement in the product container.
[0059] In some embodiments, at least two levels of bacteria removal filters 5 are connected in series in the main gas source line, for bacteria removal filtering of the gas flow in the main gas source line;
[0060] As shown in Figure 2 With the increase of the number of nitrogen filling modules, the overall nitrogen consumption increases synchronously, and the multi-stage bacteria removal filter 5 is added in the main gas source line to ensure the cleanliness of the nitrogen gas and prevent the bacteria from entering the product along with the nitrogen gas.
[0061] In addition to the nitrogen filling device disclosed in the above embodiments, the utility model also provides a product production line comprising the above-mentioned nitrogen filling device, and the structures of other parts of the product production line refer to the prior art, which will not be described herein.
[0062] The embodiments in the specification are described in a progressive manner, and each embodiment focuses on the difference from other embodiments, and the same or similar parts of each embodiment can be referred to each other.
[0063] The nitrogen filling device and the product production line provided by the utility model are introduced in detail. The principle and implementation mode of the utility model are described by applying specific examples. The above description of the examples is only used for helping to understand the method and core idea of the utility model. It should be pointed out that the ordinary skilled in the art can make some improvements and modifications to the utility model without departing from the principle of the utility model, and these improvements and modifications also fall within the protection scope of the utility model claim.
Claims
1. A nitrogen-filling device for use on a conveyor belt of a product production line to displace gas inside product containers, characterized in that, It includes several nitrogen filling modules, each nitrogen filling module including a closed gas chamber (11), the gas chamber (11) being provided with an air inlet and an air outlet, the air inlet being connected to the main gas source line; At least two sets of the nitrogen filling modules are arranged along the feed direction of the conveyor belt, and the effective working lengths of the two sets of nitrogen filling modules are different; The air outlet of the nitrogen filling module is arranged along the feeding direction of the conveyor belt, and the opening direction of the air outlet is opposite to the opening direction of the product container, so that the airflow in the gas chamber (11) can be injected into the product container through the air outlet.
2. The nitrogen charging device according to claim 1, characterized in that, The nitrogen filling module also includes a top-closed diffusion cavity (12) for the product container to pass through from its interior, and the vent is located at the top of the diffusion cavity (12).
3. The nitrogen charging device according to claim 2, characterized in that, The diffusion cavity (12) is provided with vertically arranged protective plates (14) on both sides along the gas container feeding direction to slow down the diffusion rate of the gas in the diffusion cavity (12).
4. The nitrogen charging device according to claim 1, characterized in that, The same nitrogen filling module is provided with several sets of air outlets of different diameters. The air outlets of the smallest diameter are arranged at equal intervals, and a fixed number of air outlets of other diameters are provided between two adjacent sets of air outlets of the smallest diameter.
5. The nitrogen charging device according to claim 4, characterized in that, The spacing between two adjacent sets of the smallest diameter air outlets is equal to the spacing between the product containers within the conveyor belt.
6. The nitrogen charging device according to claim 1, characterized in that, At least one set of the nitrogen filling modules is an arc-shaped structure, used to surround the pressure plug turntable (6) inside the conveyor belt; The vent is a strip-shaped structure arranged along the feeding direction of the product container. The centerline of the vent is at an angle to the centerline of the opening of the product container in the conveyor belt, and the opening of the product container is within the exhaust coverage area of the vent.
7. The nitrogen charging device according to claim 1, characterized in that, All the nitrogen filling modules are connected in parallel to the main gas source circuit, and a flow controller (4) is connected in series in the main gas source circuit.
8. The nitrogen filling device according to any one of claims 1-7, characterized in that, At least two stages of sterilization filters (5) are connected in series in the main gas source circuit for sterilization and filtration of the airflow in the main gas source circuit.
9. A product production line, characterized in that, Includes the nitrogen filling device according to any one of claims 1-8.