Simple handheld exhaled air sampling device

Abstract

The utility model provides a handheld exhaled air simple sampling device which comprises a blowing nozzle, a blowing rod, a sampling head fixing frame, a handheld frame, a heat tracing pipe, a sampling pipe, a fixing rod, an ion mobility spectrometry, a sampling air pump and a six-way valve, the blowing nozzle is connected to one end of the blowing rod and communicated with the interior of the blowing rod, the other end of the blowing rod is emptied, the blowing rod is placed on the handheld frame, and the sampling head fixing frame is arranged on the handheld frame. The handheld holding frame is placed on the sampling head fixing frame, the sampling head fixing frame is connected with the fixing rod, the heat tracing pipe is installed on the handheld holding frame, the sampling pipe is inserted into the heat tracing pipe, one end of the sampling pipe is communicated with the interior of the blowing rod, the other end of the sampling pipe is connected with the six-way valve, the six-way valve is connected with the quantitative ring, and the sampling air pump is connected with the quantitative ring through the six-way valve. The six-way valve is connected with carrier gas, and the ion mobility spectrometry is connected with the six-way valve. The device disclosed by the utility model can collect exhaled air on line, can effectively reduce adsorption and residue of samples under the action of the heat tracing pipe, has the characteristics of small sample residue, simplicity in operation, low cost and the like, and is particularly suitable for quick detection requirements.

Description

TECHNICAL FIELD

[0001] The utility model relates to a gas sampling technical field especially relates to a handheld exhaled air simple sampling device. BACKGROUND

[0002] It is increasingly recognized that measurement of exhaled air media is a new method for monitoring different aspects of disease, such as: NO is related to asthma, chronic obstructive pulmonary disease and interstitial lung disease. Therefore, exhaled air analysis can be carried out by measuring endogenous respiratory metabolites or respiratory compounds. Exhaled air detection not only analyzes the equipment, but also the exhaled air sampling device and method.

[0003] The patent file with publication number CN118050411A discloses a human exhaled air collection and detection device. The adsorbent material is placed in the exhaled air sampling tube. Under the action of the sampling pump or the human exhalation, the compounds in the exhaled air are enriched by the adsorbent material, and the collection is completed after a period of time. Then the adsorbent material is heated to release the VOCs in the adsorbent material for detection by the detection instrument, achieving the purpose of collection and detection. The device cannot reflect the change of the concentration of compounds in the exhaled air in real time.

[0004] The patent file with publication number CN117982125A discloses a human exhaled air real-time online sampling device. Under the action of the sampling pump or the human exhalation, the exhaled air enters the sampling device, and the flow direction is perpendicular to the sample inlet direction of the detection instrument. When the exhalation ends, the human exhaled air has strong adsorption characteristics, and the entire sampling device is heated uniformly. The purge hole opposite to the sample inlet is introduced to clean air to fully purge the sample inlet to achieve the purpose of self-cleaning. This method is suitable for real-time tracking of exhaled air, but cannot realize quantitative sampling of the compound concentration in the exhaled air.

[0005] The patent file with publication number CN117462108A discloses an exhaled air sampling method for eliminating the influence of humidity. The two-end opening sampling blow pipe is provided with a branch connected with the blow pipe as a blow pipe bypass. The other end of the blow pipe bypass is connected with the sample inlet of the ion mobility spectrum. An online dilution interface connected with the dilution gas source is arranged on the blow pipe bypass. The dilution gas is used to reduce the humidity of the exhaled air, but the dilution gas in the bypass can reduce the concentration of exhaled air compounds, which is not conducive to high-sensitivity detection.

[0006] There are two ways of collecting exhaled breath, offline and online. Online sampling refers to direct measurement of the exhaled breath of the testee, and real-time display of the breathing curve analysis results, while offline testing refers to collecting exhaled breath into a suitable container for delayed analysis. Compared with online technology, offline collection has the following advantages: (1) it can collect exhaled breath at a location far from the analyzer (such as a hospital room, clinic, workplace, school, and remote laboratory); (2) it is not affected by the response time of the analyzer; (3) the utilization rate of the analyzer is higher, and multiple patients' gases can be collected in sequence, reducing the analysis time for each patient. Some compounds have very similar measurement values obtained from offline collection and online measurement. However, the main problems of offline methods are: (1) there is a possibility of non-respiratory tract gas contamination; (2) sample storage introduces errors; (3) the ability to provide real-time feedback and measurement results is reduced. Online sampling method refers to direct exhalation, and then continuous sampling by an analyzer (such as ion mobility spectrometry), which displays the compound concentration curve and time in real time, with the characteristics of fast response time and less sample change. A dedicated multifunctional exhaled breath online sampler has a complex design and a cumbersome operation process, which is not conducive to rapid detection application scenarios. Therefore, a handheld exhaled breath simple sampling device is designed, which has the characteristics of fast sampling speed, small sample residue, accurate quantification, simple operation, and is especially suitable for rapid detection requirements, such as large-scale exhaled breath disease screening. Utility model content

[0007] According to the above technical problems, a handheld exhaled breath simple sampling device is provided. The utility model solves the problems of rapid collection of exhaled breath, sample residue, and quantitative analysis, realizes low loss, fast recovery, simple and efficient sampling, and accurate quantification. The technical means adopted by the utility model are as follows:

[0008] A handheld exhaled breath simple sampling device, comprising: a blow nozzle, a blow rod, a sampling head fixing frame, a handheld handle, a heat tracing pipe, a sampling pipe, a fixing rod, an ion mobility spectrometer, a sampling gas pump, and a six-way valve, the blow nozzle is connected to one end of the blow rod and communicates with the inside of the blow rod, the other end of the blow rod is empty, the blow rod is placed on the handheld handle, the handheld handle is placed on the sampling head fixing frame, the sampling head fixing frame is connected with the fixing rod, the heat tracing pipe is installed on the handheld handle, the sampling pipe is inserted into the heat tracing pipe, one end of the sampling pipe communicates with the inside of the blow rod, and the other end is connected with the six-way valve, the six-way valve is connected with a quantitative ring, the sampling gas pump is connected with the quantitative ring through the six-way valve, the six-way valve is connected with a carrier gas, and the ion mobility spectrometer is connected with the six-way valve.

[0009] Further, a boss is arranged above the handheld handle, a semicircular groove is formed in the middle of the boss, and the blow rod is movably arranged on the semicircular groove.

[0010] Further, cylindrical handles for holding are arranged on both sides of the boss.

[0011] Further, the sampling head fixing frame is a U-shaped structure, the top four corners of the U-shaped structure are provided with bosses, and the center tail is provided with a mounting hole for mounting a fixing rod.

[0012] Further, the middle part of the handheld holding frame is provided with a through hole, the heat tracing pipe is mounted in the through hole and penetrates out below the through hole, and the heat tracing pipe is a heatable hose.

[0013] Further, the blowing rod is a hollow cylinder, and a sampling port is formed in the middle of the blowing rod, and one end of the sampling pipe is inserted into the sampling port.

[0014] Further, the ion mobility spectrum is provided with a sample inlet, a drift gas inlet and a gas outlet, the sample inlet is connected with a six-way valve, and the drift gas inlet is connected with drift gas.

[0015] Further, the six-way valve is in a constant temperature state and has six ports, one of the left two ports is connected with the sampling pipe, the other port is connected with a sampling air pump, the middle two ports are connected with a quantitative ring, one of the right two ports is connected with carrier gas, and the other port is connected with the sample inlet of the ion mobility spectrum.

[0016] Further, the blowing nozzle is a disposable blowing nozzle or a mask with a filter core.

[0017] Further, the sampling pipe is a capillary tube, a PEEK tube or a tetrafluoro tube.

[0018] Compared with the prior art, the utility model has the following advantages:

[0019] 1. The handheld exhaled gas simple sampling device can collect part of the gas in the exhaled gas online, the heat tracing pipe and the six-way valve can effectively reduce the adsorption and residue of the sample, and the quantitative ring can realize quantitative sampling detection of the exhaled gas.

[0020] 2. The handheld exhaled gas simple sampling device provided by the utility model is provided with a heat tracing pipe, which can realize heat preservation of the sampling pipe.

[0021] 3. The handheld exhaled gas simple sampling device provided by the utility model is provided with a half-circular groove on the middle of the handheld holding frame, and the two sides of the boss are provided with a cylindrical handle for holding, so that the collector can hold conveniently.

[0022] Based on the above reasons, the utility model can be widely popularized in the field of gas sampling. BRIEF DESCRIPTION OF DRAWINGS

[0023] In order to more clearly illustrate the technical scheme in the embodiments of the utility model or prior art, the following will briefly introduce the drawings needed to be used in the embodiment or prior art description, obviously, the drawings in the following description are some embodiments of the utility model, and for those skilled in the art, other drawings can also be obtained without creative labor under the premise of the drawings.

[0024] Fig. 1 It is a cross-sectional structure schematic view of the utility model simple sampling device of handheld exhaled air.

[0025] Fig. 2 It is a front view of the sampling head fixing frame of the utility model.

[0026] Fig. 3 It is a front view of the handheld holding frame of the utility model.

[0027] In the drawing: 1, blow nozzle;2, blow rod;3, sampling head fixing frame;4, handheld holding frame;5, heat tracing pipe;6, sampling pipe;7, fixed rod;8, sample inlet;9, air outlet;10, gas outlet;11, ion mobility spectrum;12, sampling air pump;13, six-way valve;14, carrier gas;15, quantitative ring. DETAILED DESCRIPTION

[0028] In order to make the purpose, technical scheme and advantage of the embodiments of the utility model more clear, the following will combine the drawings in the embodiments of the utility model, and the technical scheme in the embodiments of the utility model is clearly and completely described, obviously, the described embodiments are a part of the embodiments of the utility model, rather than all the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by those skilled in the art without creative labor are within the protection scope of the utility model.

[0029] As Figs. 1-3 The utility model provides a kind of simple sampling device of handheld exhaled air applied to life health field, including blow nozzle 1, blow rod 2, sampling head fixing frame 3, handheld holding frame 4, heat tracing pipe 5, sampling pipe 6, fixed rod 7, ion mobility spectrum 11, sampling air pump 12, six-way valve 13 and quantitative ring 15, which can be collected in line exhaled air, under the action of heat tracing pipe, can effectively reduce the adsorption and residue of sample, with small sample residue, simple operation, low cost etc., especially suitable for fast detection demand.

[0030] The blow rod 2 is hollow cylindrical with a sampling port in the middle. One end of the blow rod 2 is connected to the blow nozzle 1, and the other end is empty, with the blow nozzle 1 communicating with the inside of the blow rod 2. The middle of the hand-held holder 4 has a semicircular groove, and the two sides of the semicircular groove are provided with a cylindrical handle for holding, which is convenient for the collector to hold. The blow rod 2 is movably placed in the semicircular groove of the hand-held holder 4, which is convenient for the collector to replace the blow nozzle 1 and the blow rod 2. The sampling head fixing frame 3 is a U-shaped structure, and the four corners of the upper surface are provided with a boss, and the center tail is provided with a mounting hole for mounting the fixing rod 7. The hand-held holder 4 can be placed in the sampling head fixing frame 3 to realize the placement of the sampling device.

[0031] The middle of the hand-held holder 4 is provided with a through hole, and the heat tracing pipe 5 is installed in the through hole and penetrates out below the through hole. The heat tracing pipe 5 is a heatable hose with a sampling pipe 6 inserted inside, which realizes the heat preservation of the sampling pipe 6. One end of the sampling pipe 6 is inserted into the small hole (sampling port) in the middle of the blow rod 2, and the other end is connected to one port of the six-way valve 13.

[0032] One of the two ports on the left side of the six-way valve 13 is connected to the outlet of the sampling pipe 6, and the other port is connected to the sampling gas pump 12. The middle two ports of the six-way valve 13 are connected to the constant volume ring 15, and one of the two ports on the right side of the six-way valve 13 is connected to the carrier gas 14, and the other port is connected to the sample inlet 8 of the ion mobility spectrometer 11.

[0033] Preferably, the blow nozzle 1 can be a disposable blow nozzle or a mask with a filter core.

[0034] Preferably, the sampling pipe 6 can be a capillary tube, a PEEK tube, a Teflon tube, etc.

[0035] Preferably, the six-way valve 13 is in a constant temperature state, which reduces sample residue, and the volume of the constant volume ring 15 can be adjusted according to requirements.

[0036] Preferably, the ion mobility spectrometer 11 includes a sample inlet 8, a drift gas outlet 9, and a gas outlet 10. The drift gas outlet 9 has drift gas, and the sample inlet 8 has sample gas entering.

[0037] During sampling: the six-way valve 13 realizes the communication of the sampling pipe 6 in the heat tracing pipe 5, the constant volume ring 15, and the sampling gas pump 12, and the ion mobility spectrometer 11 performs cleaning work under the sweeping of the carrier gas. The collector holds the hand-held holder 4 with both hands, puts the mouth on the blow nozzle 1 to exhale, at this time the sampling pipe 6 collects part of the gas in the exhaled gas, which enters the constant volume ring 15 through the high-temperature heat tracing pipe 5 under the action of the sampling gas pump 12. During sampling: the six-way valve 13 realizes the communication of the sampling pipe 6 in the heat tracing pipe 5 and the sampling gas pump 12, and the carrier gas 14, the constant volume ring 15 and the ion mobility spectrometer 11 are communicated, and the sample in the constant volume ring 15 enters the ion mobility spectrometer 11 for analysis and detection under the sweeping of the carrier gas 14.

[0038] Finally, it should be noted that: the above embodiments are used to illustrate the technical solutions of the present application, but not limited to them; although the present application has been described in detail with reference to the foregoing embodiments, those skilled in the art should understand that: it can still modify the technical solutions recorded in the foregoing embodiments, or make equivalent replacement to part or all of the technical features; and these modifications or replacements do not make the essence of the corresponding technical solutions deviate from the scope of the technical solutions of the embodiments of the present application.

Claims

1. A hand-held breath simple sampling device, characterized in that, It comprises a blowing nozzle (1), a blowing rod (2), a sampling head fixing frame (3), a handheld holder (4), a heat tracing pipe (5), a sampling pipe (6), a fixing rod (7), an ion mobility spectrometer (11), a sampling air pump (12) and a six-way valve (13), the blowing nozzle (1) is connected at one end of the blowing rod (2) and communicates with the inside of the blowing rod (2), the other end of the blowing rod (2) is empty, the blowing rod (2) is placed on the handheld holder (4), the handheld holder (4) is placed on the sampling head fixing frame (3), the sampling head fixing frame (3) is connected with the fixing rod (7), the heat tracing pipe (5) is installed on the handheld holder (4), the sampling pipe (6) is inserted into the heat tracing pipe (5), one end of the sampling pipe (6) communicates with the inside of the blowing rod (2), the other end is connected with the six-way valve (13), the six-way valve (13) is connected with a dosing ring (15), the sampling air pump (12) is connected with the dosing ring (15) through the six-way valve (13), the six-way valve (13) is connected with a carrier gas (14), the ion mobility spectrometer (11) is connected with the six-way valve (13). The upper part of the handheld holder (4) is provided with a boss, a semicircular groove is formed in the middle part of the boss, and the blowing rod (2) is movably placed in the semicircular groove.

2. The hand-held breath gas simple sampling device according to claim 1, characterized in that, Cylindrical handles are arranged on both sides of the boss for hand holding.

3. The hand-held breath gas simple sampling device according to claim 2, wherein, The sampling head fixing frame (3) is in a U-shaped structure, bosses are arranged at the top four corners of the U-shaped structure, and a mounting hole for mounting the fixing rod (7) is arranged at the center tail part.

4. The hand-held breath gas simple sampling device according to claim 1, wherein, A through hole is arranged in the middle part of the handheld holder (4), the heat tracing pipe (5) is installed in the through hole and penetrates out of the lower part of the through hole, and the heat tracing pipe (5) is a heatable flexible pipe.

5. The hand-held breath gas simple sampling device according to claim 1, wherein, The blowing rod (2) is in a hollow cylindrical shape, a sampling port is formed in the middle part of the blowing rod (2), and one end of the sampling pipe (6) is inserted into the sampling port.

6. The hand-held breath gas simple sampling device according to claim 1, wherein, An injection port (8), a drift gas port (9) and an outlet port (10) are arranged on the ion mobility spectrometer (11), the injection port (8) is connected with the six-way valve (13), and the drift gas port (9) is connected with a drift gas.

7. The hand-held breath gas simple sampling device according to claim 1, wherein, The six-way valve (13) is in a constant temperature state and has six ports, one port of the left two ports is connected with the sampling pipe (6), the other port is connected with the sampling air pump (12), the middle two ports are connected with the dosing ring (15), one port of the right two ports is connected with the carrier gas (14), and the other port is connected with the injection port (8) of the ion mobility spectrometer (11).

8. The hand-held breath gas simple sampling device according to claim 1, wherein, The blowing nozzle (1) is a disposable blowing nozzle or a mask with a filter core.

9. The hand-held breath gas simple sampling device according to claim 1, wherein, The sampling pipe (6) is a capillary tube, a PEEK tube or a tetrafluoro tube.

10. The hand-held breath gas simple sampling device according to claim 1, wherein, ​

Images