Biological targeting thermal therapy device for tumor treatment

By designing a bio-targeted hyperthermia device, a moving mechanism using a support plate and a sliding groove structure is used to achieve precise microwave hyperthermia of tumor sites, solving the problem of damage to normal tissues caused by existing treatment methods and improving the safety and precision of treatment.

CN223668165UActive Publication Date: 2025-12-16QINGDAO YONGJIANLONG BIOTECHNOLOGY CO LTD
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Patent Information

Application Number
CN202422947886.2
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-12-02
Publication Date
2025-12-16
Estimated Expiration
2034-12-02

AI Technical Summary

Technical Problem

Existing cancer treatments such as chemotherapy and radiotherapy can easily damage normal tissues, lack precision, and lead to significant side effects.

Method used

A biological targeted hyperthermia device was designed, which utilizes a support plate and a sliding groove structure, combined with a microwave emitting probe, to achieve precise hyperthermia of the tumor site through a moving mechanism and a stopping mechanism, thereby reducing damage to normal cells.

Benefits of technology

This improves the precision of thermotherapy, reduces accidental damage to normal cells in the patient's body, and ensures the patient's safety.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model discloses a biological targeting thermotherapy device for tumor treatment, which relates to the technical field of medical instruments and devices and comprises a supporting plate, first sliding grooves are arranged at two ends of the top of the supporting plate along the length direction, a same first fixing frame and a same second fixing frame are slidably connected in the two first sliding grooves, and the first fixing frame and the second fixing frame are identical in structure. Tooth grooves are formed in the side walls, close to each other, of the first fixing frame and the second fixing frame. After a patient lies on the supporting plate, the sliding table in the first sliding groove is driven to drive the whole fixing frame to move to the lesion position of the patient, then the shifting piece is pressed to drive the moving mechanism to slide in the fixing frame, and after the shifting piece is loosened, the stopping mechanism can prevent the moving mechanism from sliding and falling; meanwhile, the angle of the microwave emission probe can be adjusted through cooperation of the fixing plate and the damping rotating shaft, the microwave emission probe can be better aligned to the diseased region of the patient, the thermal therapy precision is improved, accidental injuries to normal cells in the body of the patient are reduced, and it is guaranteed that the patient is prevented from secondary injuries.
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Description

TECHNICAL FIELD

[0001] The utility model relates to medical instrument device technical field, concretely is biological targeting thermotherapy device for tumor treatment. BACKGROUND

[0002] Tumor refers to abnormal cell growth in a certain part of the body, these cells lose normal control mechanism in the growth process, leading to unlimited proliferation, forming a mass or occupying lesion, the formation of tumor is a complex process of multiple factors, multiple steps, involves the interaction of genetic, environment, immunity, spirit, endocrine and various factors, and tumor is divided into benign tumor and malignant tumor according to diffusion capacity, lesion location and the influence of internal organs or external skin caused by characteristics etc.

[0003] At present, the treatment method of tumor in medicine is generally surgical incision, radiotherapy, chemotherapy and the like according to tumor location and size, and because tumors are mostly located in the body, so the common treatment means is chemotherapy and radiotherapy, chemotherapy is a treatment method for stopping the proliferation, infiltration and metastasis of cancer cells by using chemical drugs until killing cancer cells, and radiotherapy is a method for killing tumor cells by using radioactive isotopes.

[0004] It can be seen that whether radiotherapy or chemotherapy, normal tissue cells of human body will also be damaged when killing tumor tissue, such as in current radiotherapy, the specificity of drug delivery is not very accurate, and normal tissue near tumor tissue will also be killed, and chemotherapy will kill cells of immune system and white blood cells, platelets and the like in blood of patients, causing damage to the body of patients, and the side effect is obvious.

[0005] Therefore, the present application is proposed. UTILITY MODEL CONTENT

[0006] The utility model is to provide biological targeting thermotherapy device for tumor treatment to solve the problems in the above background.

[0007] To solve the above technical problems, the utility model provides a biological targeting thermotherapy device for tumor treatment, including support plate, both ends of support plate top along length direction are equipped with sliding groove one, two sliding groove one all are slidably connected with same fixed frame one and fixed frame two, fixed frame one and fixed frame two structure are same, fixed frame one and fixed frame two mutually close one side wall all are equipped with tooth slot, fixed frame one and fixed frame two mutually close one side wall all are slidably connected with same mobile mechanism of one, mobile mechanism includes two symmetrical mobile parts of setting, two mobile parts mutually close one side are equipped with same microwave emission probe, mobile part inside is equipped with stop mechanism, stop mechanism includes respectively rotationally connected drive gear on two parallel outer walls of mobile part, two drive gears are meshedly connected in two tooth slots, two drive gears mutually close one side wall center all are fixedly connected with same pivot one, pivot one outer arc wall is fixedly connected with two ratchets, two ratchets are meshedly connected with pawl on the side away from the center of support plate, the end of pawl away from ratchet is fixedly connected with horizontal pawl, two pawls mutually close one side wall is fixedly connected with pivot two, the end of pawl away from pivot two is rotationally connected on the inner wall of mobile part,

[0008] The teeth of the ratchets in the two mobile parts are oppositely arranged, one end of the outer arc wall of one of the pawls away from the pivot two is fixedly connected with a limit gear, one end of the limit gear away from the ratchet is meshedly connected with a vertical rack plate, a push piece is installed on the side wall of the rack plate away from the limit gear, and the push piece penetrates through the side wall of the mobile part.

[0009] Further, the mobile part is a hollow structure, the drive gear is located outside the mobile part, and the remaining components of the stop mechanism are located inside the mobile part. A sliding groove two is formed in the side wall of the mobile part away from the support plate, the push piece penetrates through the side wall of the mobile part away from the support plate and is slidably connected in the sliding groove two, a spring telescopic rod one is fixedly connected to the push piece at one end away from the inner wall of the sliding groove two, and the other end of the spring telescopic rod one is fixedly connected to the rack plate.

[0010] Further, a vertical sliding groove three is formed in the middle of the side wall of the push piece close to the rack plate, a limit block is fixedly connected to the rack plate at one end away from the microwave emission probe, the limit block is slidably connected in the sliding groove three, a spring telescopic rod two is fixedly connected to the inner wall of the sliding groove three at one end away from the limit block, and the other end of the spring telescopic rod two is fixedly connected to the limit block.

[0011] Further, the two moving parts are symmetrically arranged at the center of the side close to each other, and the side close to each other of the two moving parts is concave, and the two moving parts are fixedly connected with the fixed plates of the same structure at the end close to each other, and the side wall of the fixed plate is provided with a transversely penetrating channel one, and the two fixed plates on the same side are staggered and the channels one penetrate each other, and the channel one on the two fixed plates on the same side is rotatably connected with the same damping shaft.

[0012] Further, the side wall close to each other of the two damping shafts is fixedly connected with the same shaft sleeve, the longitudinal section of the shaft sleeve is annular structure, the inside of the shaft sleeve is fixedly connected with the microwave emission probe, and the end of the microwave emission probe away from the support plate is fixedly connected with the handle.

[0013] Further, the middle part of the fixed frame one is semicircular and the arc opening is arranged towards the support plate, the fixed frame two is the same structure as the fixed frame one and is arranged in parallel, and the length direction of the sliding groove one is consistent with the length direction of the support plate.

[0014] Further, the electric guide rail is laid in the sliding groove one, the sliding block is slidably connected on the electric guide rail, the bottom of the fixed frame one is fixedly connected with the two sliding blocks respectively, and the bottom of the fixed frame two is fixedly connected with the two sliding blocks respectively.

[0015] Further, the two sliding grooves on the moving parts are located on the same side, and the shaft one is rotatably connected with the moving part.

[0016] Compared with the prior art, the beneficial effects of the utility model are:

[0017] After the patient lies on the support plate, the sliding table in the sliding groove one drives the fixed frame to move to the lesion of the patient, then the moving mechanism is driven to slide in the fixed frame by pressing the pressing piece, and when the pressing piece is released, the stopping mechanism can prevent the moving mechanism from sliding down, and the cooperation of the fixed plate and the damping shaft can adjust the angle of the microwave emission probe, so that the lesion part of the patient can be better aligned, the precision of the heat treatment is improved, the normal cells in the patient's body are less damaged, and the patient is protected from secondary damage. BRIEF DESCRIPTION OF DRAWINGS

[0018] Figure 1 It is an external structure diagram of the moving mechanism in the biological targeting heat treatment device for tumor treatment.

[0019] Figure 2 It is an overall structure diagram of the biological targeting heat treatment device for tumor treatment.

[0020] Figure 3 It is an internal structure diagram of the moving mechanism in the biological targeting heat treatment device for tumor treatment.

[0021] Figure 4 The structure diagram of the dial piece in the biological targeting hyperthermia device for tumor treatment.

[0022] In the figure:

[0023] 10, support plate; 11, fixed frame one; 12, fixed frame two;

[0024] 20, microwave emission probe; 21, handle; 22, fixed plate; 23, damping rotating shaft; 24, shaft sleeve; 25, moving part;

[0025] 30, stop mechanism; 31, driving gear; 32, ratchet wheel; 33, pawl; 34, dial piece; 35, rack plate; 36, limiting gear; 37, spring telescopic rod one;

[0026] 40, limiting block; 41, spring telescopic rod two. DETAILED DESCRIPTION

[0027] The technical solutions in the embodiments of the present application will be clearly and completely described below with reference to the drawings in the embodiments of the present application. Obviously, the described embodiments are only part of the embodiments of the present application, rather than all the embodiments. Based on the embodiments in the present application, all the other embodiments obtained by those skilled in the art without creative labor fall within the scope of protection of the present application.

[0028] Please refer to Figures 1-4 The present application provides a technical solution: a support plate 10 is provided with a sliding groove one at each end along the length direction on the top, and a same fixed frame one 11 and a fixed frame two 12 are slidably connected in the two sliding grooves one, the fixed frame one 11 and the fixed frame two 12 are the same in structure, a tooth groove is arranged on the side wall of the fixed frame one 11 and the fixed frame two 12 which are close to each other, and a same moving mechanism is slidably connected on the side wall of the fixed frame one 11 and the fixed frame two 12 which are close to each other, the moving mechanism comprises two symmetrically arranged moving parts 25, a same microwave emission probe 20 is arranged on the side of the two moving parts 25 which are close to each other, a stop mechanism 30 is arranged in the moving part 25, the stop mechanism 30 comprises driving gears 31 which are rotatably connected to the two parallel outer walls of the moving part 25, the two driving gears 31 are respectively meshingly connected in the two tooth grooves, a same rotating shaft one is fixedly connected at the center of the side wall of the two driving gears 31 which are close to each other, two ratchet wheels 32 are fixedly connected on the outer arc wall of the rotating shaft one, pawls 33 are meshingly connected on the side of the two ratchet wheels 32 which are away from the center of the support plate 10, the pawls 33 are fixedly connected at the end which is away from the ratchet wheel 32, a rotating shaft two is fixedly connected on the side wall of the two pawls 33 which are close to each other, and the end of the pawl 33 which is away from the rotating shaft two is rotatably connected to the inner wall of the moving part 25.

[0029] The teeth of the ratchets 32 in the two moving parts 25 are oppositely arranged, one pawl 33 is fixedly connected with a limiting gear 36 at the outer arc wall far from the second end of the rotating shaft, the limiting gear 36 is meshingly connected with a vertical rack plate 35 far from the ratchet 32, the rack plate 35 is installed with a push piece 34 on the side wall far from the limiting gear 36, and the push piece 34 penetrates through the side wall of the moving part 25;

[0030] The first sliding groove is internally arranged with an electric guide rail, the electric guide rail is slidably connected with sliding blocks, the bottom of the first fixed frame 11 is fixedly connected with the two sliding blocks respectively, the bottom of the second fixed frame 12 is fixedly connected with the two sliding blocks respectively, the second sliding grooves on the two moving parts 25 are located at the same side, and the first rotating shaft is rotatably connected with the moving part 25.

[0031] It should be noted that the support plate 10 provides support for the patient, which can be a bed or a surgical table for biological target hyperthermia in actual application, and the support plate 10 is installed with a support structure at the bottom of four corners to support the support plate 10 and the whole device, and the support plate 10 is provided with a driving source and a control terminal (not shown in the figure) inside the bottom or the support structure or on one side of the support plate 10 to drive the microwave emission probe 20;

[0032] The moving mechanism is a mechanism for driving the microwave emission probe 20 to move in the tooth groove where the first fixed frame 11 and the second fixed frame 12 are close to each other, and the stop mechanism 30 arranged in the two moving parts 25 is used to limit the moving mechanism after moving, and prevent the moving mechanism from being touched or falling by mistake;

[0033] When the push piece 34 on one side is pressed, the push piece 34 will drive the stop mechanism 30 in the moving part 25 to release the restriction of the pawl 33 on the ratchet 32, so that the moving mechanism can move in this direction, and the ratchet 32 and the pawl 33 in the moving part 25 on the other side are in an unlocked state, that is, the pawl 33 will not block or affect the rotation of the ratchet 32.

[0034] Please refer to Figures 1-4 The utility model provides a technical scheme: the moving part 25 is of hollow structure, the driving gear 31 is located outside the moving part 25, and the stop mechanism 30 is arranged with the rest of the components in the moving part 25, wherein the moving part 25 is provided with a second sliding groove on the side wall far from the support plate 10, the push piece 34 penetrates through the side wall of the moving part 25 far from the support plate 10 and is slidably connected in the second sliding groove, a spring telescopic rod one 37 is fixedly connected on the inner side wall close to the microwave emission probe 20 of the second sliding groove, and one end of the spring telescopic rod one 37 far from the inner wall of the second sliding groove is fixedly connected on the push piece 34.

[0035] Need to explain: the sliding groove two through moving part 25 is set, the length of the tab 34 at the outside of the moving part 25 is greater than the length of the tab 34 inside the moving part 25 and the end of the tab 34 away from the inside of the moving part 25 is provided with a counterweight, so that the center of gravity of the tab 34 can be stabilized on the axis of the spring telescopic rod one 37.

[0036] Please refer to Figures 1-4 The utility model provides a technical scheme: the tab 34 is equipped with vertical sliding groove three in the middle of one side wall close to the rack plate 35, the rack plate 35 is fixedly connected with limit block 40 on one side wall close to the tab 34 away from the microwave emission probe 20, the limit block 40 is slidably connected in the sliding groove three, the limit block 40 is fixedly connected with spring telescopic rod two 41 on one side wall close to the microwave emission probe 20, and the end of the spring telescopic rod two 41 away from the limit block 40 is fixedly connected on the inner wall of the sliding groove three.

[0037] Need to explain: the cross section of limit block 40 is trapezoidal, and the cross section of sliding groove three is trapezoidal, which is matched with the trapezoidal cross section of limit block 40, when the moving mechanism moves, the tab 34 in the pressing direction can move towards the direction, and when the ratchet wheel 32 on the other side rotates, the teeth of the ratchet wheel 32 will push the pawl 33 away, and then the limit gear 36 is rotated and fed back to the rack plate 35;

[0038] If the limit block 40 and the spring telescopic rod two 41 are lost, first, when the moving mechanism moves, the limit gear 36 will act on the rack plate 35 and then on the tab 34, so a greater force is needed to move the moving mechanism, second, when the limit gear 36 acts on the rack plate 35, the tab 34 will be deflected towards the limit gear 36 with the connection between the tab 34 and the spring telescopic rod one 37 as the center, and after a long time, the connection between the tab 34 and the spring telescopic rod one 37 will be damaged due to excessive force, and then the tab 34 will be damaged;

[0039] Therefore, the limit block 40 and the spring telescopic rod two 41 can absorb the effect of the reaction force generated by the limit gear 36 on the rack plate 35 when the moving mechanism moves away from the moving direction, so as to protect the tab 34, and because the end of the rack plate 35 is engaged with the limit gear 36 at this time, the spring telescopic rod two 41 is compressed when the limit gear 36 continues to rotate, and when the spring telescopic rod two 41 is compressed to a certain extent, the rack plate 35 is no longer engaged with the limit gear 36, and at this time, the rack plate 35 is reset under the action of the spring telescopic rod two 41.

[0040] Please refer to Figures 1-4The utility model provides a technical scheme: two mobile parts 25 about two mutually close one side center place symmetry arrangement, two mobile parts 25 mutually close one side all are concave, two mobile parts 25 mutually close one end all fixedly connected with the fixed plate 22 of same structure, the lateral wall of fixed plate 22 is equipped with the channel one of horizontal through -going, the fixed plate 22 of same side is staggered and arranged and the channel one is mutually through, the channel one of the fixed plate 22 of same side is rotated and is connected with the same damping shaft 23 in,

[0041] Two damping shafts 23 mutually close one lateral wall fixedly connected with same shaft sleeve 24, the shaft sleeve 24 longitudinal section is annular structure, the microwave emission probe 20 is fixedly connected in the shaft sleeve 24 interior, the microwave emission probe 20 is fixedly connected with handle 21 away from support plate 10 one end, the fixed frame one 11 middle part is semicircular and sets up with the arc mouth to support plate 10, and fixed frame two 12 and fixed frame one 11 structure are same and mutually parallel arrangement, and the length direction of sliding slot one is consistent with the length direction of support plate 10.

[0042] Need to explain is: fixed plate 22 makes that two mobile parts 25 between can adaptively mutually rotate, when moving mechanism moves to the arc segment of fixed frame one 11 and fixed frame two 12, two mobile parts 25 between can adaptively rotate to make drive gear 31 can better with the gear teeth in the gear groove meshing,

[0043] Damping shaft 23 can make shaft sleeve 24 rotate in the recess of mobile part 25 mutually close a certain angle to better adapt to different treatment needs.

[0044] Working principle:

[0045] Through the injection of heat -sensing material combined with tumor tissue antibody in patient's body, utilize the specific recognition ability of antibody, heat -sensing material is accurately guided to tumor tissue, and the microwave emission probe 20 is exported under the instruction of control device wavelength and frequency microwave radiation, and heat -sensing material generates heat in microwave radiation field, and then kill tumor;

[0046] When adjusting microwave emission probe 20, press the dial piece 34 of corresponding position, can drive moving mechanism to move in the gear groove towards the side of pressed dial piece 34, release dial piece 34 prevents moving mechanism from sliding and falling under the action of stop mechanism 30 to cause safety accident, and simultaneously operating personnel can hold handle 21 to manually adjust microwave emission probe 20 output port orientation to better adapt to treatment needs.

Claims

1. A biological targeted hyperthermia device for tumor treatment, comprising a support plate (10), wherein both ends of the top of the support plate (10) along the length direction are provided with a first groove, and the same first fixing frame (11) and second fixing frame (12) are slidably connected in both first grooves, the first fixing frame (11) and the second fixing frame (12) have the same structure, and the side walls of the first fixing frame (11) and the second fixing frame (12) that are close to each other are provided with toothed grooves, characterized in that: One of the side walls of the fixed frame one (11) and the fixed frame two (12) is slidably connected with the same moving mechanism, the moving mechanism comprises two symmetrically arranged moving parts (25), one side of the two moving parts (25) is provided with the same microwave emission probe (20), the inside of the moving part (25) is provided with a stop mechanism (30), the stop mechanism (30) comprises a drive gear (31) rotatably connected to the two parallel outer walls of the moving part (25), the two drive gears (31) are respectively meshed and connected in the two tooth grooves, the center of the side wall of the two drive gears (31) is fixedly connected with the same shaft one, the outer arc wall of the shaft one is fixedly connected with two ratchets (32), the side of the two ratchets (32) away from the center of the support plate (10) is meshed and connected with a pawl (33), one end of the pawl (33) away from the ratchet (32) is fixedly connected with a horizontal pawl (33), the side wall of the two pawls (33) close to each other is fixedly connected with a shaft two, one end of the pawl (33) away from the shaft two is rotatably connected to the inner wall of the moving part (25); The teeth of the ratchets (32) in the two moving parts (25) are oppositely arranged, one end of the outer arc wall of one of the pawls (33) away from the shaft two is fixedly connected with a limiting gear (36), one end of the limiting gear (36) away from the ratchet (32) is meshed and connected with a vertical rack plate (35), the side wall of the rack plate (35) away from the limiting gear (36) is installed with a push piece (34), the push piece (34) penetrates through the side wall of the moving part (25).

2. The biotargeted hyperthermia device for tumor therapy according to claim 1, characterized in that: The moving part (25) is a hollow structure, the drive gear (31) is located outside the moving part (25), and the remaining parts of the stop mechanism (30) are located inside the moving part (25), wherein a sliding groove two is formed in the side wall of the moving part (25) away from the support plate (10), the push piece (34) penetrates through the side wall of the moving part (25) away from the support plate (10) and is slidably connected in the sliding groove two, a spring telescopic rod one (37) is fixedly connected to the inner side wall of the sliding groove two close to the microwave emission probe (20), and one end of the spring telescopic rod one (37) away from the inner wall of the sliding groove two is fixedly connected to the push piece (34).

3. The biotargeted hyperthermia device for tumor therapy according to claim 1, wherein: A vertical sliding groove three is arranged in the middle of the side wall of the push piece (34) close to the rack plate (35), a limiting block (40) is fixedly connected to the side wall of the rack plate (35) away from the microwave emission probe (20), the limiting block (40) is slidably connected in the sliding groove three, a spring telescopic rod two (41) is fixedly connected to the side wall of the limiting block (40) close to the microwave emission probe (20), and one end of the spring telescopic rod two (41) away from the limiting block (40) is fixedly connected to the inner wall of the sliding groove three.

4. The biotargeted hyperthermia device for tumor therapy according to claim 1, wherein: Two moving parts (25) are symmetrically arranged at the center of the side close to each other, the side close to each other of two moving parts (25) is concave, the side close to each other of two moving parts (25) is fixedly connected with the same fixed plate (22), the side wall of fixed plate (22) is provided with a transversely penetrating channel one, two fixed plates (22) on the same side are staggered and the channels one are penetrated with each other, the same damping shaft (23) is rotatably connected in the channel one on the same side of two fixed plates (22).

5. The biologically targeted hyperthermia treatment device for tumor treatment as claimed in claim 4, wherein: the magnetic field generator is a permanent magnet; and the magnetic field generator is arranged to be moved in a circular motion by a magnetic field generator moving device. The side wall close to each other of two damping shafts (23) is fixedly connected with the same shaft sleeve (24), the longitudinal section of shaft sleeve (24) is annular structure, the microwave emission probe (20) is fixedly connected in the inside of shaft sleeve (24), the handle (21) is fixedly connected to the end of microwave emission probe (20) away from the supporting plate (10).

6. The biotargeted hyperthermia device for tumor therapy according to claim 1, wherein: The middle part of the fixed frame one (11) is semicircular and the arc opening is arranged towards the supporting plate (10), the fixed frame two (12) is the same structure as the fixed frame one (11) and is arranged parallel to each other, the length direction of the sliding groove one is consistent with the length direction of the supporting plate (10).

7. The biotargeted hyperthermia device for tumor therapy according to claim 1, wherein: the biotargeted hyperthermia device is a magnetic nanoparticle. The electric guide rail is laid in the sliding groove one, the sliding block is slidably connected on the electric guide rail, the bottom of the fixed frame one (11) is fixedly connected with two sliding blocks respectively, the bottom of the fixed frame two (12) is fixedly connected with two sliding blocks respectively.

8. The biotargeted hyperthermia device for tumor therapy according to claim 1, wherein: The sliding grooves two on two moving parts (25) are located on the same side, and the rotating shaft one is rotatably connected with the moving part (25).