Tear drop type ampoule tube strain cryopreservation box
By designing a teardrop-shaped ampoule cryopreservation box with a support structure and temperature monitoring, the problems of ampoules being easily broken and accidentally touched were solved, maintaining the biological activity of the seeds and ensuring operational safety, and achieving stable temperature control and efficient transfer.
Patent Information
- Application Number
- CN202422911663.0
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-11-27
- Publication Date
- 2025-12-26
- Estimated Expiration
- 2034-11-27
AI Technical Summary
The opening of existing teardrop-shaped ampoules is spiky after being melted and sealed at high temperatures, which can easily cut hands and break. The slender teardrop-shaped ampoules lack good stress points, making it easy to accidentally touch the seeds during transfer, affecting biological activity. Similar problems exist when sampling and observing.
A teardrop-shaped ampoule cryopreservation box for bacterial cultures was designed, comprising a base, a support structure, and a top cover. The support structure includes a circular hole and a support column. The support column extends obliquely and matches the arc-shaped structure on the inner side of the top cover to form an installation gap, supporting and limiting the position of the ampoule. Combined with cooling materials and temperature sensor monitoring, it ensures that the ampoule does not tip over during transportation.
It effectively supports and limits the ampoule tube, preventing accidental contact and overturning, maintaining the biological activity of the seeds, ensuring a stable temperature environment, and improving operational safety and sample quantity.
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Figure CN223723105U_ABST
Abstract
Description
TECHNICAL FIELD
[0001] The utility model belongs to the technical field of microorganism freeze-drying preservation, especially relates to a tear drop type ampoule strain cryopreservation box. BACKGROUND
[0002] In the field of biological medicine, the advantages of maintaining the initial biological properties by using strain freeze-drying, the freeze-drying of tear drop type ampoule as a carrier is an important link affecting the quality of microorganisms.
[0003] At present, the opening of the existing tear drop type ampoule is often in the form of a sharp structure after high-temperature fusion sealing. On the one hand, the sharp end is not only easy to scratch the hand, but also easy to break and expose the biological sample. On the other hand, the thin and long tear drop type ampoule lacks a good stress point for stacking, and each time the microorganism seed is transferred or used, it is likely to accidentally touch the water drop type bottom. The high-temperature difference may change the biological activity of the seed and affect its quality. At the same time, the above-mentioned problems also exist when the sample is observed and the cryopreserved sample is taken, which affects research and production. UTILITY MODEL CONTENT
[0004] The utility model aims at overcoming the defects of the prior art and provides a tear drop type ampoule strain cryopreservation box which can effectively support the thin and long tear drop type ampoule, avoid accidentally touching the tear drop of the ampoule and cool it at the same time. The mounting gap formed by the first arc-shaped structure on the support column and the second arc-shaped structure on the inner side of the top cover can limit the ampoule during transportation and avoid the ampoule from being overturned and dumped, thereby affecting the biological activity of the seed.
[0005] The utility model is realized by the following technical scheme:
[0006] A tear drop type ampoule strain cryopreservation box, comprising a base and a plurality of support structures arranged on the base, wherein the support structure comprises a circular hole opened on the surface of the base and a support column arranged on the surface of the base, the circular hole and the support column are used for fixing the ampoule, and a cooling material corresponding to the position of the circular hole is further arranged in the base to enable the tear drop of the ampoule to contact the cooling material, and a box body and a top cover are sequentially arranged on the base.
[0007] The diameter of the circular hole is smaller than the diameter of the tear drop of the ampoule, the support column is located on the right side of the circular hole and extends in the direction close to the circular hole, the top of the support column has a first arc-shaped structure in contact with the body of the ampoule, the inner side of the top cover further has a second arc-shaped structure matched with the first arc-shaped structure, the mounting gap is formed between the first arc-shaped structure and the second arc-shaped structure, the body of the ampoule is arranged in the mounting gap, and the maximum size of the mounting gap is smaller than the diameter of the tear drop of the ampoule.
[0008] In one embodiment, the surface of the base is further provided with a plurality of temperature probe points, and a recess for mounting a digital temperature sensor is formed in the side wall of the box body, and the digital temperature sensor is electrically connected with the temperature probe points.
[0009] By the embodiment, the average temperature in the box body is monitored in real time by the plurality of temperature probe points, so that the seeds in the ampoule are in a suitable temperature environment, and the biological activity of the seeds is avoided from being affected.
[0010] In one embodiment, the cooling material is a plurality of ice bags arranged in the base, and a window is formed in one side of the base for taking and placing the ice bags.
[0011] By the embodiment, the ice bags in the base are conveniently replaced, so that the heat preservation effect on the ampoule is maintained.
[0012] In one embodiment, a mounting recess is formed in the outer side wall of the box body, the digital temperature sensor is arranged in the mounting recess, and the inner side wall of the box body is covered with a first heat preservation layer.
[0013] In one embodiment, the inner wall of the base is circumferentially covered with a second heat preservation layer.
[0014] In one embodiment, the first heat preservation layer and the second heat preservation layer are both made of a high molecular adsorption resin material.
[0015] In one embodiment, the outer side of the top cover is provided with a box buckle, and the top of the box body is provided with a buckle card corresponding to the box buckle.
[0016] In one embodiment, the circular holes and the support columns in the support structure are transversely staggered on the base.
[0017] In one embodiment, the height of the support column is 2-3 cm.
[0018] In one embodiment, the inclination angle of the support column is 30-40°.
[0019] The utility model discloses the beneficial effect lies in:
[0020] (1) the circular hole in the base can effectively support the long teardrop-shaped ampoule, avoid touching the teardrop-shaped ampoule, and the cooling material corresponding to the position of the circular hole cools the teardrop-shaped ampoule, maintains the biological activity of the seeds in it, and the first arc structure on the support column and the second arc structure in the inner side of the top cover are matched with each other, and the mounting gap formed can limit the ampoule during the transportation, so that the biological activity of the seeds is avoided from being affected.
[0021] (2) The design that the support column extends obliquely is beneficial to the operation personnel to take and store, and the transverse staggered arrangement of the plurality of support columns on the base is beneficial to improve the number of samples that can be placed. BRIEF DESCRIPTION OF DRAWINGS
[0022] The utility model will be described in further detail below based on the embodiments and with reference to the drawings.
[0023] Among them:
[0024] Figure 1 The structure schematic diagram of the utility model is shown;
[0025] Figure 2 The schematic diagram when one support structure of the utility model operates is shown;
[0026] In the drawings, the same components use the same reference numerals. The drawings are not in accordance with the actual scale.
[0027] Reference numerals:
[0028] 1 - buckle, 2 - box buckle, 3 - top cover, 4 - round hole, 5 - ampoule tube, 6 - support column, 7 - window pane, 8 - base, 9 - second arc structure, 10 - digital display temperature sensor, 11 - thermometer probe, 12 - box body, 601 - first arc structure. DETAILED DESCRIPTION
[0029] The utility model will be described in further detail below based on the embodiments and with reference to the drawings.
[0030] The utility model provides a tear drop type ampoule tube strain freezing box, as shown in Figure 1 The utility model provides a tear drop type ampoule tube strain freezing box, as shown in
[0031] Among them, the diameter of round hole 4 is less than the diameter of tear drop of ampoule tube 5, support column 6 is located at the right side of round hole 4, and it extends obliquely towards the direction close to round hole 4, the top of support column 6 has the first arc structure 601 that the tube body of ampoule tube 5 contacts, the inner side of top cover 3 is further provided with the second arc structure 9 that mutually coincides with first arc structure 601, and the installation gap is formed between first arc structure 601 and second arc structure 9, the tube body of ampoule tube 5 is arranged in installation gap, and the maximum size of installation gap is less than the diameter of tear drop of ampoule tube 5;
[0032] Need to explain is, asFigure 1 and Figure 2 As shown in the figure, the teardrop of ampoule 5 is arranged at the circular hole 4 opened on the upper surface of the base 8, the cooling material in the base 8 cools the ampoule 5, and the support column 6 arranged on the right side of the circular hole 4 supports the tube body of the ampoule 5, the first arc-shaped structure 601 on the support column 6 matches the second arc-shaped structure 9 hanging inside the top cover 3, that is, when the top cover 3 is buckled with the box body 12, the second arc-shaped structure 9 matches the first arc-shaped structure 601 of the support column 6, under the action of gravity, the two matched half-arc-shaped structures form a closed mounting gap, the tube body of the ampoule 5 is located in the mounting gap, and the maximum size of the mounting gap is smaller than the diameter of the teardrop of the ampoule 5, and there is a small distance between the two matched half-arc-shaped structures and the teardrop of the ampoule 5, which is used for buffering, so that even if shaking occurs during transportation, the situation of overturning and pouring can be avoided;
[0033] In one embodiment, as shown in the figure, Figure 1 The surface of the base 8 is also provided with a plurality of point-shaped distributed thermometer probes 11, and the side wall of the box body 12 is provided with a recess for mounting the digital temperature sensor 10, the digital temperature sensor 10 is electrically connected with the thermometer probe 11, and the thermometer probe 11 can be connected with the digital temperature sensor 10 through the hidden wire close to the support column, that is, the plurality of point-shaped distributed thermometer probes 11 are used to monitor the average temperature in the box body 12 in real time, so that the seeds in the ampoule 5 are in a suitable temperature environment, and the biological activity is not affected;
[0034] In one embodiment, the cooling material is a plurality of ice bags arranged in the base 8, and one side of the base 8 is provided with a window 7 for taking and placing the ice bags, that is, the window 7 is arranged on one side of the base 8, and the window 7 is mounted on the base 8 by means of the embedded buckle, so that the ice bags in the base 8 can be replaced to maintain the heat preservation effect of the ampoule 5;
[0035] In one embodiment, the outer side wall of the box body 12 is provided with a mounting recess, the digital temperature sensor 10 is arranged in the mounting recess, the inner side wall of the box body 12 is covered with a first heat preservation layer, and the inner wall of the base 8 is covered with a second heat preservation layer along the circumference thereof;
[0036] Specifically, the first heat preservation layer and the second heat preservation layer are both made of high molecular adsorption resin material, which can absorb the water generated in the box body to reduce the temperature in the box body;
[0037] In one embodiment, as shown in the figure, Figure 1 The outer side of the top cover 3 is provided with a box buckle 2, and the top of the box body 12 is provided with a buckle 1 corresponding to the box buckle 2, that is, the top cover 3 and the box body 12 are fixed by means of the mutually matched box buckle 2 and buckle 1;
[0038] In one embodiment, the round holes 4 and the support columns 6 in the support structure are arranged transversely and staggeredly on the base 8;
[0039] Specifically, the height of the support column 6 is 2-3 cm, and the inclination angle of the support column 6 is 30-40°;
[0040] It should be noted that, as shown in Figure 1 and Figure 2 , the round holes 4 and the support columns 6 in the support structure are arranged transversely and staggeredly on the base 8, so that as many ampoules 5 as possible can be placed in the box body 12, and the parameters of the support column 6 are designed to facilitate the experimental operation technicians to take and store the ampoules 5;
[0041] In one embodiment, before use, the window 7 on the side wall of the base 8 is opened, a plurality of pre-cooling ice bags are placed in the base 8, and then the closure is buckled. Open the top cover 3, vertically stretch the top cover 3, and the second arc-shaped structure 9 connected thereto is also separated, hold the sealed ampoule 5 by hand, place the tube part of the ampoule 5 on the first arc-shaped structure 601 of the support column 6, and at the same time make the tear drop ball part of the ampoule 5 accurately fall into the round hole 4 and directly contact the lower ice bag. After the ampoules 5 are placed in the support columns 6 in the entire box body 12 in turn, the box body 12 and the top cover 3 are buckled, at this time the second arc-shaped structure 9 accurately matches the first arc-shaped structure 601 of the support column 6, and the ampoule 5 is limited and protected, and finally the switch of the digital temperature sensor 10 is opened. Rely on the temperature probe 11 distributed in dots in the box body 12 to monitor the temperature throughout the process.
[0042] In the description of the present application, it should be understood that the terms "upper", "lower", "bottom", "top", "front", "back", "inner", "outer", "left", "right" and the like indicate the orientation or positional relationship based on the orientation or positional relationship shown in the drawings, and are only for the convenience of describing the present application and simplifying the description, and do not indicate or imply that the devices or elements referred to must have a particular orientation, be constructed and operated in a particular orientation, therefore it cannot be understood as a limitation of the present application.
[0043] Although the present application is described herein with reference to specific embodiments, it should be understood that these embodiments are only examples of the principles and applications of the present application. Therefore, it should be understood that many modifications can be made to the exemplary embodiments, and other arrangements can be designed, as long as they do not deviate from the spirit and scope of the present application defined in the appended claims. It should be understood that different dependent claims and features described herein can be combined in ways different from the original claims. It should also be understood that the features described in conjunction with a single embodiment can be used in other described embodiments.
Claims
1. A droplet-shaped ampoule vial cryobox, characterized by, The base and a plurality of support structures arranged on the base, the support structure comprises a round hole opened on the surface of the base and a support column arranged on the surface of the base, the round hole and the support column are used for fixing ampoule, the base is further provided with cooling material corresponding to the position of the round hole, so that the tear drop of the ampoule contacts with the cooling material, the base is sequentially provided with a box body and a top cover; The diameter of the round hole is smaller than the diameter of the tear drop of the ampoule, the support column is located on the right side of the round hole and extends in the direction of approaching the round hole, the top of the support column has a first arc-shaped structure which contacts with the tube body of the ampoule, the inner side of the top cover is further provided with a second arc-shaped structure which is matched with the first arc-shaped structure, the first arc-shaped structure and the second arc-shaped structure form an installation gap, the tube body of the ampoule is arranged in the installation gap, and the maximum size of the installation gap is smaller than the diameter of the tear drop of the ampoule.
2. A droplet-shaped ampoule vial cryobox according to claim 1, characterized in that, The surface of the base is further provided with a plurality of point-shaped distributed thermometer probes, the box body is provided with a digital temperature sensor, and the digital temperature sensor is electrically connected with the thermometer probe.
3. A droplet-shaped ampoule vial cryobox according to claim 1, wherein, The cooling material is a plurality of ice bags arranged in the base, and one side of the base is provided with a window for taking and placing the ice bag.
4. A droplet-shaped ampoule vial cryobox according to claim 2, wherein, The outer side wall of the box body is provided with a mounting groove, the digital temperature sensor is arranged in the mounting groove, and the inner side wall of the box body is covered with a first heat preservation layer.
5. A droplet-shaped ampoule vial cryobox according to claim 4, characterized in that, The inner wall of the base is covered with a second heat preservation layer along the circumference thereof.
6. A droplet-shaped ampoule vial cryobox according to claim 5, characterized in that, The first heat preservation layer and the second heat preservation layer are both made of high molecular adsorption resin material.
7. A droplet-shaped ampoule vial cryobox according to claim 1, wherein, The outer side of the top cover is provided with a box buckle, and the top of the box body is provided with a buckle card corresponding to the box buckle.
8. The droplet-shaped ampoule vial cryobox according to claim 1, wherein, The round hole and the support column in the support structure are transversely staggered on the base.
9. The droplet-shaped ampoule vial cryobox according to claim 1, wherein, The height of the support column is 2-3cm.
10. A droplet-shaped ampoule vial cryobox according to claim 1 or 9, characterized in that, The inclination angle of the support column is 30-40°.