Enzyme immunoassay test lotion preparation device
By designing an enzyme immunoassay washing solution preparation device, which uses a liquid pump and flow meter to automatically control the preparation of enzyme immunoassay washing solution, the problem of tedious and time-consuming manual preparation is solved, and efficient and low-cost washing solution preparation is achieved.
Patent Information
- Application Number
- CN202520532441.X
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2025-03-25
- Publication Date
- 2025-12-30
- Estimated Expiration
- 2035-03-25
AI Technical Summary
In existing technologies, the preparation process of enzyme immunoassay plate washing solution is cumbersome, time-consuming, and prone to errors, resulting in low work efficiency.
Design an enzyme immunoassay washing solution preparation device, including a frame, washing solution preparation tank, concentrate tank and distilled water tank. The preparation is automated by liquid pump and flow meter. The preparation ratio is controlled by control module. The solution can be stirred and mixed by air pump during the preparation process.
It automates the preparation of washing solutions, reduces manual workload, improves work efficiency, and reduces errors. It is simple in structure and low in cost.
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Figure CN223732667U_ABST
Abstract
Description
TECHNICAL FIELD
[0001] The utility model relates to liquid mixing and preparing device, especially to an enzyme-free experiment washing liquid preparing device. BACKGROUND
[0002] When the hospital or blood station adopts enzyme-free experiment to detect blood-borne infectious diseases (such as hepatitis B, hepatitis C, AIDS, syphilis, etc.) of blood samples, there will be a plate washing link in the experiment process, and a large amount of plate washing liquid is needed for plate washing. The plate washing liquid provided by the reagent box is concentrated washing liquid, and the concentrated liquid of different reagent manufacturers has different specifications such as 25ml, 30ml or 50ml, which needs to be prepared according to the proportion of 1:19 of concentrated liquid and distilled water when used. The staff generally prepares it manually by using measuring cylinders and beakers, first pours a certain amount of concentrated washing liquid into a washing liquid preparation barrel, and then pours the corresponding amount of distilled water into the washing liquid preparation barrel according to the proportion. During the preparation process, the amount of concentrated washing liquid poured in needs to be recorded, and then the amount of distilled water needed is calculated, and then the distilled water is repeatedly measured by using the measuring cylinder and beaker until the required volume of liquid is obtained. According to the different detection workload, the required plate washing liquid for the experiment may be several liters to several tens of liters, which leads to large workload, long time consumption, low efficiency and easy calculation or measurement error of manual preparation of plate washing liquid. Therefore, an automatic enzyme-free experiment washing liquid preparation device is needed to improve the efficiency of washing liquid preparation, reduce the workload of people and further improve the overall work efficiency. SUMMARY
[0003] The technical problem to be solved by the utility model is to provide an enzyme-free experiment washing liquid preparation device capable of automatically preparing washing liquid.
[0004] To solve the above problems, the technical scheme adopted by the utility model is:
[0005] An enzyme-free experiment washing liquid preparation device, the key technology of which lies in that it comprises a rack, one washing liquid preparation barrel and one or more concentrated liquid barrels arranged on the rack, and a distilled water barrel, the two ends of a concentrated liquid pipeline are connected with the concentrated liquid barrel and the washing liquid preparation barrel respectively, a liquid pump and a flow meter are arranged on the concentrated liquid pipeline, the two ends of a distilled water pipeline are connected with the distilled water barrel and the washing liquid preparation barrel respectively, a liquid pump and a flow meter are arranged on the distilled water pipeline, a liquid outlet head is arranged on the rack, and the liquid outlet head is connected with the washing liquid preparation barrel through a liquid outlet pipeline.
[0006] As an embodiment of the utility model, it further comprises an air pump, and the exhaust end of the air pump is connected with the washing liquid preparation barrel through an air blowing pipeline.
[0007] As an embodiment of the utility model, the rack is a rectangular frame structure, a support plate is arranged in the middle of the rectangular frame structure, the washing liquid preparation barrel is arranged on the support plate, and the concentrated liquid barrels are arranged on the bottom plate.
[0008] As an embodiment of the utility model, the distilled water barrel is placed outside the rack, and the distilled water pipeline is connected with the distilled water barrel through an external connecting pipe.
[0009] As an embodiment of the utility model, the liquid pump four and the flow meter four are arranged on the liquid outlet pipeline.
[0010] As an embodiment of the utility model, the two concentrated liquid barrels include a concentrated liquid barrel one and a concentrated liquid barrel two, the liquid pump one and the flow meter one are arranged on the concentrated liquid pipeline connected with the concentrated liquid barrel one and the concentrated liquid barrel two, and the liquid pump two and the flow meter two are arranged on the concentrated liquid pipeline connected with the concentrated liquid barrel two and the concentrated liquid barrel one.
[0011] As an embodiment of the utility model, the inside of the washing liquid preparation barrel, the concentrated liquid barrel and the distilled water barrel is provided with a hose extending to the bottom of the barrel and connected with the corresponding pipeline.
[0012] As an embodiment of the utility model, the washing liquid preparation barrel, the concentrated liquid barrel and the distilled water barrel are all provided with a barrel cover, and the pipeline extends into the barrel through the through hole arranged on the barrel cover.
[0013] The above technical scheme has the following beneficial effects:
[0014] The enzyme-free experiment washing liquid preparation device has the advantages of simple and practical overall structure, low manufacturing cost and maintenance cost. The medical staff only needs to fill the small-size concentrated liquid into the concentrated liquid barrel, the liquid pump can pour the concentrated liquid and distilled water into the washing liquid preparation barrel according to the preset proportion, realizes automatic liquid preparation operation, since the concentrated liquid barrel can add multiple bottles of concentrated liquid at a time, the distilled water barrel and the washing liquid preparation barrel can also be set to have a large capacity, so that a large amount of washing liquid can be prepared at a time according to the needs, or the washing liquid can be prepared multiple times in small amounts, and the workload of the person is greatly reduced. BRIEF DESCRIPTION OF DRAWINGS
[0015] Figure 1 is a structure schematic view of an embodiment 1 of the utility model.
[0016] Figure 2 is a structure schematic view of an embodiment 2 of the utility model.
[0017] Figure 3 is a structure schematic view of a hose arranged in the concentrated liquid barrel.
[0018] Wherein: 1 rack, 1-1 bottom plate, 1-2 side plate, 2 support plate, 3 concentrated liquid barrel one, 4 concentrated liquid barrel two, 5 washing liquid preparation barrel, 6 distilled water barrel, 7 liquid pump one, 8 liquid pump two, 9 flow meter one, 10 flow meter two, 11 air pump, 12 liquid pump three, 13 flow meter three, 14 liquid pump four, 15 flow meter four, 16 liquid outlet head, 17 connecting pipe. DETAILED DESCRIPTION
[0019] In order to make the purpose, technical scheme and advantages of the utility model more clear, the utility model will be described clearly and completely below in combination with specific embodiments.
[0020] As Figure 1 shown in a kind of enzyme-free experiment washing liquid preparation device, it includes rack 1, be set on rack 1 one washing liquid preparation barrel 5 and more than one concentrated liquid barrel, and a distilled water barrel 6, concentrated liquid pipeline both ends are connected the concentrated liquid barrel and washing liquid preparation barrel 5 5, concentrated liquid pipeline is provided with liquid pump and flow meter, distilled water pipeline both ends are connected distilled water barrel 6 and washing liquid preparation barrel 5, and distilled water pipeline is provided with liquid pump three 12 and flow meter three 13, the rack 1 is provided with liquid outlet head 16, the liquid outlet head 16 is connected with washing liquid preparation barrel 5 by liquid outlet pipeline. Wherein liquid outlet pipeline connects the bottom position of washing liquid preparation barrel 5, and liquid outlet head 16 is at the bottom position of washing liquid preparation barrel 5 or below its bottom surface position, so that the washing liquid prepared in washing liquid preparation barrel 5 can flow out by liquid outlet head 16 under the action of gravity. Liquid outlet head 16 can be provided with liquid outlet switch. Dosage cup or scale quantitative container is taken washing liquid by liquid outlet head 16.
[0021] The embodiment also includes air pump 11, the exhaust end of the air pump 11 is connected with the washing liquid preparation barrel 5 by air blowing pipeline, for carrying out air blowing to washing liquid preparation barrel 5, reaches the purpose of stirring and mixing. Air pump is used to carry out air blowing stirring to washing liquid preparation barrel, can reach the purpose of mixing, while the overall structure is simple, is convenient for maintenance. As equivalent alternative form, mechanical stirring using reduction motor to drive stirring paddle can also be used;Manual stirring can also be used, and stirring port is opened in the middle of washing liquid preparation barrel 5, and manual stirring is carried out by stirring rod from stirring port.
[0022] Referring to Figure 1 and Figure 2As shown, the concentrate barrels are two, namely concentrate barrel one 3 and concentrate barrel two 4, liquid pump one 7 and flow meter one 9 are arranged on the concentrate pipeline connected with the concentrate barrel one 3 and the concentrate pipeline connected with the concentrate barrel two 4 and the washing liquid preparation barrel 5, liquid pump two 8 and flow meter two 10 are arranged on the concentrate pipeline connected with the concentrate barrel two 4 and the washing liquid preparation barrel 5. The two concentrate barrels can be designed as the same specification or different specifications, and the capacity is preferably about 1000ml. In use, the concentrate barrel one 3 and the concentrate barrel two 4 can be respectively put into different concentrates for preparing different washing liquids.
[0023] The distilled water barrel 6 is placed outside the rack 1, and the distilled water pipeline is connected with the distilled water barrel 6 through the external connecting pipe 17. The capacity of the distilled water barrel 6 is preferably about 20L, and the capacity of the washing liquid preparation barrel 5 is preferably 10-20L. Placing the distilled water barrel 6 outside the rack 1 reduces the burden of the rack 1, reduces the requirements for the structural strength and accommodation space of the rack 1, and reduces the overall volume, which is more flexible and convenient. At the same time, since the equipment has a large amount of distilled water, placing the distilled water barrel 6 outside the rack 1 also facilitates the replacement or water taking of the distilled water barrel 6.
[0024] In this embodiment, the rack 1 is a rectangular frame structure, including a bottom plate 1-1 at the bottom and side plates 1-2 fixed on both sides of the bottom plate 1-1, and a support plate 2 is fixedly arranged at the middle of the two side plates 1-2, the washing liquid preparation barrel 5 is arranged on the support plate 2, and the concentrate barrel is arranged on the bottom plate 1-1. As a further improvement, a back plate can be arranged at the back of the rack 1, a top plate is arranged at the top, and a box door that can be opened is arranged at the front, so that the rack 1 forms a closed box structure.
[0025] The washing liquid preparation barrel 5, the concentrate barrel and the distilled water barrel 6 are all arranged with hoses extending into the bottom and connected with the corresponding pipelines (see Figure 3 ). The washing liquid preparation barrel 5, the concentrate barrel and the distilled water barrel 6 are all arranged with barrel covers, and the pipelines extend into the barrels through the through holes (not shown in the figure) arranged on the barrel covers. In this way, the washing liquid preparation barrel 5, the concentrate barrel and the distilled water barrel 6 can be taken out for liquid adding, water adding, cleaning, replacement and other operations.
[0026] As a preferred embodiment, as shown in Figure 2 The liquid pump four 14 and the flow meter four 15 are arranged on the liquid outlet pipeline, and the liquid outlet pipeline extends into the washing liquid preparation barrel 5 through the through hole of the barrel cover at the top of the washing liquid preparation barrel 5. The liquid pump four 14 delivers the prepared washing liquid to the liquid outlet head 16, and the washing liquid is output from the liquid outlet head 16.
[0027] In the above embodiments, each of the liquid pumps, flow meters, and air pumps 11 is connected to the control module, and each liquid pump, flow meter, and air pump 11 is connected to a built-in or external power supply. The control module sets the ratio and volume of the washing solution preparation. For example, for washing solution one, the ratio of concentrated liquid to distilled water is set to 1:19, and the volume of one preparation is selectable from 1 to 10L. After selecting the volume of the washing solution, the control module controls liquid pump one 7 and liquid pump three 12 to work simultaneously, drawing concentrated liquid and distilled water from concentrated liquid tank one 3 and distilled water tank six, respectively. Flow meters one 9 and three 13 monitor the volume of the drawn concentrated liquid and distilled water, respectively. When the drawn volume reaches the preset value, the control module controls the corresponding liquid pump to stop working. During the preparation process, the control module controls the air pump 11 to work synchronously, blowing air into the preparation tank to achieve the effect of stirring and mixing. Similarly, when it is necessary to prepare washing solution two, liquid pump two 8 and flow meter two 10 work to prepare washing solution two using the concentrate in concentrate tank two 4 and distilled water.
[0028] Before preparing different cleaning solutions, a certain amount of distilled water can be added to the cleaning solution preparation tank 5, aerated and stirred, and then the distilled water in the cleaning solution preparation tank 5 can be discharged through the outlet 16 to complete the cleaning of the cleaning solution preparation tank 5 and the outlet pipe. Alternatively, the cleaning solution preparation tank 5 can be removed, a certain amount of distilled water can be added for cleaning, and then it can be used again.
[0029] In the above embodiments, the liquid pump can be a peristaltic pump (such as the T100-1B small flow OEM peristaltic pump) or a diaphragm pump (such as the KNF FEM 1.02 series diaphragm pump), the flow meter can be an electromagnetic flow meter (Microflow type), and the control module can be a multi-channel RS485 controller (such as the Lange T100-SC series controller).
[0030] Although the present invention has been described in detail with reference to the foregoing embodiments, those skilled in the art can still modify the technical solutions described in the foregoing embodiments or make equivalent substitutions for some of the technical features; and these modifications or substitutions do not cause the essence of the corresponding technical solutions to deviate from the spirit and scope of the technical solutions of the embodiments of the present invention.
Claims
1. An enzyme immunoassay wash solution dispensing device characterized by: It includes a rack (1), a washing liquid preparation barrel (5) and more than one concentrated liquid barrel arranged on the rack (1), and a distilled water barrel (6), the concentrated liquid pipeline is connected with the concentrated liquid barrel and the washing liquid preparation barrel (5) at both ends respectively, liquid pumps and flow meters are arranged on the concentrated liquid pipeline, the distilled water pipeline is connected with the distilled water barrel (6) and the washing liquid preparation barrel (5) at both ends respectively, liquid pumps and flow meters are arranged on the distilled water pipeline, the rack (1) is provided with a liquid outlet head (16), the liquid outlet head (16) is connected with the washing liquid preparation barrel (5) through a liquid outlet pipeline; the liquid pumps and the flow meters are connected with a control module.
2. An enzyme immunoassay wash solution preparation device according to claim 1, wherein: It also includes an air pump (11), the exhaust end of the air pump (11) is connected with the washing liquid preparation barrel (5) through an air blowing pipeline.
3. The enzyme immunoassay wash solution dispensing device of claim 1, wherein: The rack (1) is a rectangular frame structure, a support plate (2) is arranged in the middle, the washing liquid preparation barrel (5) is arranged on the support plate (2), and the concentrated liquid barrel is arranged on the bottom plate (1-1).
4. The enzyme immunoassay wash solution dispensing device of claim 1, wherein: The distilled water barrel (6) is arranged outside the rack (1), and the distilled water pipeline is connected with the distilled water barrel (6) through an external connecting pipe (17).
5. The enzyme immunoassay wash solution dispensing device of claim 1, wherein: Liquid pump four (14) and flow meter four (15) are arranged on the liquid outlet pipeline.
6. The enzyme immunoassay wash solution dispensing device of claim 1, wherein: The concentrated liquid barrel is two, including concentrated liquid barrel one (3) and concentrated liquid barrel two (4), liquid pump one (7) and flow meter one (9) are arranged on the concentrated liquid pipeline connected with the washing liquid preparation barrel (5) of the concentrated liquid barrel one (3), liquid pump two (8) and flow meter two (10) are arranged on the concentrated liquid pipeline connected with the washing liquid preparation barrel (5) of the concentrated liquid barrel two (4).
7. The enzyme immunoassay wash solution dispensing device of claim 1, wherein: The washing liquid preparation barrel (5), the concentrated liquid barrel and the distilled water barrel (6) are all provided with hoses extending into the bottom and connected with the corresponding pipelines.
8. The enzyme immunoassay wash solution dispensing device of claim 1, wherein: The washing liquid preparation barrel (5), the concentrated liquid barrel and the distilled water barrel (6) are all provided with barrel covers, and the pipelines extend into the barrels through the through holes arranged on the barrel covers.