Host cell protein detection kit

Abstract

The utility model provides a host cell protein detection kit, which relates to the technical field of cell protein detection and comprises a kit body and a kit cover arranged on the kit body. According to the test tube box, firstly, test tubes filled with samples to be tested are placed in the test tube placing grooves, the elastic pieces and the rubber plates on the fixing blocks can fix the test tubes to prevent the test tubes from moving or inclining in the subsequent operation process, and when the test tubes need to be taken out or replaced, the test tubes can be conveniently taken out or replaced. The test tubes can be taken out only by slightly shifting the elastic sheets to separate the rubber plates from the test tubes, and when the box body is subjected to external impact, the impact force is absorbed through the cooperation of the buffer damping and the telescopic springs, so that the safety of the test tubes is ensured; the fixing assembly and the buffering assembly can be fixed in the box body or taken out of the box body, and therefore the effect that the test tubes can be buffered and stably fixed in the box body is achieved.

Description

TECHNICAL FIELD

[0001] The utility model relates to cell protein detection technical field especially relates to a host cell protein detection kit. BACKGROUND

[0002] The host cell protein detection kit is mainly used for detecting the pollution of recombinant protein in the host cell expression process, and the kit can recognize the host cell derived protein through specific antibody, help screening and confirming the purity of recombinant protein, ensure product quality, and effectively prevent the interference of host cell protein on downstream application (such as drug development, vaccine production, etc.).

[0003] However, in actual use, there are still the following deficiencies, for example: the existing host cell protein detection kit cannot realize buffering and stable fixation of test tubes in the box body, and the test tubes may be broken due to vibration, collision and other reasons during transportation or operation. This not only leads to sample loss, but also may cause harm to laboratory personnel, if the test tubes are not stably fixed, the sample may leak to other parts of the reagent box, leading to cross contamination, affecting the accuracy of the detection result, and unstable test tube fixation may lead to inconsistent operation conditions of each experiment, thereby affecting the repeatability and reliability of the experimental results.

[0004] Therefore, the utility model provides a host cell protein detection kit to solve the above problems. UTILITY MODEL CONTENT

[0005] The utility model aims at solving the shortcomings in the prior art and provides a host cell protein detection kit.

[0006] In order to realize the above-mentioned purpose, the utility model adopts the following technical scheme: a host cell protein detection kit, comprising:

[0007] The box body and the box cover arranged on the box body;

[0008] The fixing assembly is arranged in the box body and close to one side of the top, the fixing assembly comprises a supporting block arranged in the box body and close to one side of the top, a test tube placing groove is formed in the supporting block, a fixing block is fixedly connected to one side of the top of the supporting block close to the test tube placing groove, a spring sheet is fixedly connected to the fixing block, and a rubber plate is fixedly connected to one side of the spring sheet close to the test tube placing groove;

[0009] A buffering assembly is arranged on one side of the bottom of the support block, and the buffering assembly comprises a bottom plate arranged on the bottom of the box body, a first support plate rotatably connected to the bottom plate, a buffering damper fixedly connected to the first support plate, a second support plate fixedly connected to one end of the buffering damper away from the first support plate, an extension spring arranged on the buffering damper, and a clamping plate fixedly connected to the bottom plate.

[0010] As a preferred embodiment, the box cover is rotatably connected to one side of the box body.

[0011] The beneficial effect of the above further scheme is that when the box needs to be opened, the box cover can be turned over to expose the space in the box body, and when the box needs to be closed, the box cover can be turned back to its original position to cover the box body and protect the test tubes inside.

[0012] As a preferred embodiment, the second support plate is rotatably connected to the bottom of the support block, one end of the extension spring is fixedly connected to the first support plate, and the other end of the extension spring is fixedly connected to the second support plate.

[0013] The beneficial effect of the above further scheme is that the second support plate is rotatably connected to the bottom of the support block, so that the buffering assembly as a whole can be connected to the support block, one end of the extension spring is fixedly connected to the first support plate, and the other end of the extension spring is fixedly connected to the second support plate, so that the extension spring can provide a buffering effect on the support block and the test tubes arranged on the support block through the cooperation of the buffering damper and the extension spring.

[0014] As a preferred embodiment, a limiting groove is arranged on one side of the support block close to the clamping plate, the clamping plate is slidingly connected in the limiting groove, and the clamping plate is arranged in the clamping groove.

[0015] The beneficial effect of the above further scheme is that the limiting groove is arranged on one side of the support block close to the clamping plate, and the clamping plate is slidingly connected in the limiting groove, so that the limiting groove can limit the clamping plate, and the clamping plate is arranged in the clamping groove, so that the fixing assembly and the buffering assembly as a whole can be fixed inside the box body.

[0016] As a preferred embodiment, a heating assembly is arranged on the box cover, the heating assembly comprises a hot air blower mounted on one side of the box cover, and an air inlet is arranged on one side of the box cover close to the hot air blower.

[0017] The beneficial effect of the above further scheme is that the heating assembly generates hot air through the hot air blower, which enters from the air inlet of the box cover and enters the box body through the ventilation holes on the support block.

[0018] As a preferred implementation, the support block is provided with a ventilation hole, and the box body is provided with an air outlet on one side.

[0019] The beneficial effect of the further scheme is that the interior is heated, the heated gas is discharged from the air outlet of the box body, forming a circulation, and ensuring that the temperature in the reagent box is uniform and stable.

[0020] As a preferred implementation, the box body is rotatably connected with a clamping block on one side, and the box cover is fixedly connected with a clamping seat on the side close to the clamping block.

[0021] The beneficial effect of the further scheme is that when the box cover is closed, the clamping block cooperates with the clamping seat to lock the box cover on the box body by rotation, ensuring that the reagent box will not be accidentally opened during transportation or use.

[0022] Compared with the prior art, the reagent box has the advantages and positive effects that:

[0023] In the reagent box, first, the sample to be measured is placed in the test tube, and then the test tube is placed in the test tube placing groove on the support block. At this time, the spring sheet and the rubber plate on the fixing block will fix the test tube to prevent it from moving or tilting during subsequent operations. When the test tube needs to be taken out or replaced, the spring sheet is only slightly poked to separate the rubber plate from the test tube, so that the test tube can be easily taken out or a new test tube can be easily placed. At the same time, in order to protect the test tube from being damaged during transportation or use, the buffer assembly plays a key role. When the box body is subjected to external impact, the impact force is absorbed through the cooperation of the buffer damping and the extension spring, ensuring the safety of the test tube. The clamping plate is inserted into or pulled out of the clamping groove on the box body, so that the fixing assembly and the buffer assembly can be fixed in or taken out of the box body, thereby realizing the buffering and stable fixing of the test tube in the box body. BRIEF DESCRIPTION OF DRAWINGS

[0024] Figure 1 It is a structural schematic view of the reagent box for detecting host cell proteins according to the present application;

[0025] Figure 2 It is a structural schematic view of the fixing assembly and the buffer assembly of the reagent box for detecting host cell proteins according to the present application;

[0026] Figure 3 It is a structural schematic view of the fixing assembly of the reagent box for detecting host cell proteins according to the present application;

[0027] Figure 4 It is a structural schematic view of the buffer assembly of the reagent box for detecting host cell proteins according to the present application.

[0028] REFERENCE SIGNS:

[0029] 1. Box body; 2. Box lid;

[0030] 3. Fixing component; 31. Support block; 32. Test tube placement slot; 33. Fixing block; 34. Spring; 35. Rubber plate;

[0031] 4. Buffer assembly; 41. Base plate; 42. First support plate; 43. Buffer damping; 44. Second support plate; 45. Telescopic spring; 46. Locking plate; 47. Limiting groove; 48. Locking slot;

[0032] 5. Heating components; 51. Hot air blower; 52. Air inlet; 53. Ventilation hole; 54. Air outlet;

[0033] 6. Card block; 7. Card slot. Detailed Implementation

[0034] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0035] like Figures 1-4 As shown, this embodiment provides a technical solution: a host cell protein detection kit, comprising:

[0036] Box body 1 and box lid 2 provided on box body 1;

[0037] Fixing component 3 is placed inside the box 1 near the top. Fixing component 3 includes a support block 31 located inside the box 1 near the top. The support block 31 has a test tube placement slot 32. A fixing block 33 is fixedly connected to the top of the support block 31 near the test tube placement slot 32. A spring piece 34 is fixedly connected to the fixing block 33. A rubber plate 35 is fixedly connected to the spring piece 34 near the test tube placement slot 32.

[0038] The buffer assembly 4 is arranged on one side of the bottom of the support block 31, and the buffer assembly 4 comprises a bottom plate 41 arranged at the bottom of the box body 1, a first support plate 42 rotatably connected to the bottom plate 41, a buffer damping 43 fixedly connected to the first support plate 42, a second support plate 44 fixedly connected to one end of the buffer damping 43 away from the first support plate 42, an extension spring 45 arranged on the buffer damping 43, a clamping plate 46 fixedly connected to the bottom plate 41, and a clamping groove 48 formed on one side of the box body 1 close to the clamping plate 46. First, the sample to be tested is placed in the test tube, and then the test tube is placed in the test tube placing groove 32 on the support block 31. At this time, the spring sheet 34 and the rubber plate 35 on the fixed block 33 will fix the test tube to prevent it from moving or tilting during subsequent operations. When the test tube needs to be taken out or replaced, the spring sheet 34 is only slightly poked to separate the rubber plate 35 from the test tube, so that the new test tube can be easily taken out or placed. At the same time, in order to protect the test tube from being damaged during transportation or use, the buffer assembly 4 plays a key role. When the box body 1 is subjected to external impact, the impact force is absorbed by the buffer damping 43 and the extension spring 45, ensuring the safety of the test tube. By inserting or pulling out the clamping plate 46 from the clamping groove 48 on the box body 1, the fixing assembly 3 and the buffer assembly 4 can be fixed in the box body 1 or taken out from the box body 1, so that the test tube in the box body 1 can be buffered and stably fixed.

[0039] In the above scheme, the reagent kit cannot meet the problem of uniform and stable temperature in the reagent kit during transportation, such as Figure 1 As shown in the figure, the box cover 2 is rotatably connected to one side of the box body 1. Since the box cover 2 is rotatably connected to one side of the box body 1, when the box needs to be opened, the box cover 2 can be turned over to expose the space in the box body 1. When the box needs to be closed, the box cover 2 can be turned back to the original position to cover the box body 1 and protect the internal test tube.

[0040] As shown in the figure, Figures 1-2 and Figure 4As shown, the second support plate 44 is rotatably connected to the bottom of the support block 31, one end of the telescopic spring 45 is fixedly connected to the first support plate 42, and the other end of the telescopic spring 45 is fixedly connected to the second support plate 44. Since the second support plate 44 is rotatably connected to the bottom of the support block 31, the buffer assembly 4 as a whole can be connected to the support block 31. Since one end of the telescopic spring 45 is fixedly connected to the first support plate 42, and the other end of the telescopic spring 45 is fixedly connected to the second support plate 44, the telescopic spring 45 can provide a buffering effect on the support block 31 and the test tube arranged on the support block 31 through the cooperation of the buffer damping 43 and the telescopic spring 45. The side of the support block 31 close to the clamping plate 46 is provided with a limiting groove 47, and the clamping plate 46 is slidably connected in the limiting groove 47. The clamping plate 46 is arranged in the clamping groove 48. Since the side of the support block 31 close to the clamping plate 46 is provided with the limiting groove 47, and the clamping plate 46 is slidably connected in the limiting groove 47, the limiting groove 47 can limit the clamping plate 46. Since the clamping plate 46 is arranged in the clamping groove 48, the fixing assembly 3 and the buffer assembly 4 as a whole can be fixed in the box body 1;

[0041] As shown in Figures 1-4 The box cover 2 is provided with a heating assembly 5. The heating assembly 5 includes a hot air machine 51 mounted on one side of the box cover 2. The side of the box cover 2 close to the hot air machine 51 is provided with an air inlet 52. The heating assembly 5 generates hot air through the hot air machine 51, which enters from the air inlet 52 of the box cover 2. The hot air enters the box body 1 through the ventilation holes 53 on the support block 31. The ventilation holes 53 are arranged on the support block 31. The side of the box body 1 is provided with an air outlet 54 to heat the inside. The heated gas is discharged from the air outlet 54 of the box body 1 to form a circulation, ensuring that the temperature in the reagent box is uniform and stable.

[0042] As shown in Figure 1 The side of the box body 1 is rotatably connected with a clamping block 6. The side of the box cover 2 close to the clamping block 6 is fixedly connected with a clamping seat 7. When the box cover 2 is closed, the clamping block 6 cooperates with the clamping seat 7 to lock the box cover 2 on the box body 1 by rotating, ensuring that the reagent box will not be accidentally opened during transportation or use.

[0043] Working principle:

[0044] As shown in Figures 1-4As shown, first, the sample to be tested is placed in the test tube, and then the test tube is placed in the test tube placing groove 32 on the support block 31, at this time, the elastic sheet 34 and the rubber plate 35 on the fixing block 33 will fix the test tube, prevent it from moving or tilting during subsequent operation, when it is necessary to take out or replace the test tube, just flick the elastic sheet 34, make the rubber plate 35 separate from the test tube, and then easily take out or put in a new test tube, at the same time, in order to protect the test tube from being damaged during transportation or use, the buffer assembly 4 plays a key role, when the box body 1 is impacted by the outside, the impact force is absorbed by the buffer damping 43 and the cooperation of the extension spring 45, to ensure the safety of the test tube, the clamping plate 46 is inserted or pulled out of the clamping groove 48 on the box body 1, so that the fixing assembly 3 and the buffer assembly 4 can be fixed in the box body 1 or taken out from the box body 1, the heating assembly 5 generates hot air through the air heater 51, enters from the air inlet 52 of the box cover 2, the hot air enters the box body 1 through the ventilation hole 53 on the support block 31, heats the inside, and the heated gas is discharged from the air outlet 54 of the box body 1, forms a cycle, ensures that the temperature in the reagent box is uniform and stable, when the box cover 2 is closed, the clamping block 6 cooperates with the clamping seat 7, locks the box cover 2 on the box body 1 by rotating, ensures that the reagent box will not be opened accidentally during transportation or use.

[0045] The above is only a preferred embodiment of the present application, and is not intended to limit the present application in other forms. Any skilled person in the art can modify or change the above disclosed technical content to equivalent embodiments applied to other fields, but any simple modification, equivalent change and modification of the above embodiments without departing from the technical scheme of the present application, according to the technical essence of the present application, still belongs to the protection scope of the present application.

Claims

1. A host cell protein detection kit, characterized in that, The utility model relates to a box body (1) and the box cover (2) set up on the box body (1) are included. Fixing assembly (3) is placed in the box body (1) near the top one side, and the fixing assembly (3) includes the support block (31) set up in the box body (1) near the top one side, the test tube placement groove (32) is seted up on the support block (31), the fixed block (33) is fixedly connected with the support block (31) near the test tube placement groove (32) one side on the top, the fixed block (33) is fixedly connected with the spring sheet (34), the rubber plate (35) is fixedly connected with the spring sheet (34) near the test tube placement groove (32) one side on the top. Buffering assembly (4) is placed in the support block (31) bottom one side, and the buffering assembly (4) includes the bottom plate (41) set up in the box body (1) bottom, the first support plate (42) is rotatably connected with the bottom plate (41), the buffering damping (43) is fixedly connected with the first support plate (42), the second support plate (44) is fixedly connected with the buffering damping (43) away from the first support plate (42) one end, the telescopic spring (45) is seted up on the buffering damping (43), the clamping plate (46) is fixedly connected with the bottom plate (41), the clamping groove (48) is seted up in the box body (1) near the clamping plate (46) one side. The box cover (2) is rotatably connected on one side of the box body (1).

2. A host cell protein detection kit according to claim 1, characterized in that: The second support plate (44) is rotatably connected on the bottom of the support block (31), one end of the telescopic spring (45) is fixedly connected on the first support plate (42), the other end of the telescopic spring (45) is fixedly connected on the second support plate (44).

3. A host cell protein detection kit according to claim 1, characterized in that: The limiting groove (47) is seted up on the support block (31) near the clamping plate (46) one side, the clamping plate (46) is slidably connected in the limiting groove (47), and the clamping plate (46) is seted up in the clamping groove (48).

4. The host cell protein detection kit according to claim 1, characterized in that: The heating assembly (5) is seted up on the box cover (2), and the heating assembly (5) includes the air heater (51) installed on one side of the box cover (2), and the air inlet (52) is seted up on one side of the box cover (2) near the air heater (51).

5. The host cell protein detection kit according to claim 1, characterized in that: Ventilation holes (53) are seted up on the support block (31), and the air outlet (54) is seted up on one side of the box body (1).

6. The host cell protein detection kit according to claim 1, characterized in that: The clamping block (6) is rotatably connected on one side of the box body (1), and the clamping seat (7) is fixedly connected on one side of the box cover (2) near the clamping block (6).

7. The host cell protein detection kit according to claim 1, characterized in that: ​

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