Medicine production friability tester

Abstract

The utility model relates to the technical field of medicine, and discloses a medicine production friability inspection tester which comprises a first installation box and a second installation box, the first installation box is arranged at the end of the second installation box, a first installation cavity is formed in the first installation box, and a second installation cavity is formed in the second installation box. A moving mechanism is arranged in the first mounting cavity, through the arrangement of the moving mechanism, medicine is placed in the second mounting cavity, a servo motor is started, the servo motor drives a rotating shaft and a rotating disc on the outer side of the rotating shaft to rotate, a fixing column and a sliding groove are clamped in a sliding mode, a rotating block is driven to swing, and first teeth and second teeth are in meshing transmission; the servo motor drives the moving column to reciprocate and drives the extruding plate to extrude medicines, the extruding force of the extruding plate to the medicines is controlled by controlling the rotating speed of the servo motor, the servo motor has high-precision speed and position control capacity, fine adjustment can be achieved, and it is guaranteed that the extruding force of each time is consistent.

Description

Technical Field

[0001] This utility model relates to the field of pharmaceutical technology, specifically a friability testing instrument for pharmaceutical production. Background Technology

[0002] Pharmaceutical manufacturing is a complex and meticulous process involving multiple stages, from research and development, raw material procurement, manufacturing, quality control to final product release. Ensuring the safety, efficacy, and consistency of drug quality is paramount throughout this process. Below is a brief overview of the pharmaceutical manufacturing process. First, pharmaceutical research and development forms the foundation of pharmaceutical manufacturing. This includes the discovery of new drugs, preclinical studies, and clinical trials. Researchers explore new compounds, test their biological activities, and validate their safety and efficacy through rigorous clinical trials. Once a drug is approved and enters the manufacturing phase, manufacturers need to procure high-quality raw materials. These raw materials include active pharmaceutical ingredients and excipients, which must meet stringent regulatory standards and quality requirements. Next is the manufacturing process, which typically takes place in a highly controlled environment. Manufacturing steps may include mixing, tableting, capsule filling, and formulation of liquid dosage forms, depending on the type of drug. Quality control is an integral part of pharmaceutical manufacturing. Rigorous quality checks are conducted at each stage of production, including testing of raw materials, intermediate products, and final products. These tests ensure that the product meets predetermined quality standards and is free of impurities or contaminants. Packaging is also a crucial aspect of pharmaceutical manufacturing. Pharmaceuticals need to be properly packaged to protect their stability and provide necessary instructions for use and safety information. Packaging materials must be sterile and suitable for the storage conditions of the medicine. Finally, after final quality inspection, the finished drug is distributed to medical institutions, pharmacies, or other distribution channels, ultimately reaching patients. The entire pharmaceutical manufacturing process is subject to strict supervision by drug regulatory agencies in various countries, such as the FDA in the United States and the EMA in the European Union, to ensure public health and safety.

[0003] Currently, without hardness testing, breakage or wear during storage or transportation of drugs may lead to increased exposure of drug components, thereby affecting the stability and safety of the drugs. Therefore, this does not meet the existing needs. To address this, we propose a pharmaceutical manufacturing friability testing instrument. Utility Model Content

[0004] This invention provides a pharmaceutical manufacturing friability testing instrument, which has the beneficial effect of ensuring consistent extrusion force each time. It solves the problem mentioned in the background art that if the drug does not have hardness testing, breakage or wear during storage or transportation may lead to increased exposure of drug components, thereby affecting the stability and safety of the drug.

[0005] This utility model provides the following technical solution: a pharmaceutical manufacturing friability tester, comprising a first mounting box and a second mounting box, the first mounting box being disposed at the end of the second mounting box, the first mounting box having a first mounting cavity inside, the second mounting box having a second mounting cavity inside, and a moving mechanism being disposed inside the first mounting cavity.

[0006] As an optional solution for the pharmaceutical production friability testing instrument described in this utility model, a compression plate is provided inside the second mounting cavity, and the moving mechanism is used in conjunction with the compression plate.

[0007] As an optional solution for the pharmaceutical production friability testing instrument described in this utility model, a servo motor is connected to the side of the first mounting box, and the output shaft of the servo motor passes through the side of the first mounting box.

[0008] As an optional solution for the pharmaceutical production friability testing instrument described in this utility model, wherein: a rotating shaft is connected to the inner wall of the first mounting cavity, a turntable is sleeved on the outer side of the rotating shaft, and the output shaft of the servo motor is keyed to the rotating shaft.

[0009] As an optional solution for a pharmaceutical production friability testing instrument according to this utility model, the moving mechanism includes a locking plate and a moving column, and the locking plate and the moving column are disposed inside the first mounting cavity.

[0010] As an optional solution for the pharmaceutical production friability tester described in this utility model, the side of the locking plate is provided with a sliding groove, and the side of the rotating disk is connected to a fixed column, the fixed column and the sliding groove are slidably engaged.

[0011] As an optional solution for the pharmaceutical production friability tester of this utility model, wherein: a rotating block is connected to the end of the locking plate, a plurality of first teeth are connected to the side of the rotating block, a retaining ring is connected to the inner wall of the first mounting cavity, the moving column is inserted into the inside of the retaining ring, a second tooth is connected to the side of the moving column, the first teeth and the second teeth mesh and drive each other, and the moving column is connected to the side of the extrusion plate.

[0012] As an optional solution for the pharmaceutical production friability tester described in this utility model, a piston block is connected to the side of the extrusion plate, and a piston groove is provided on the inner wall of the second mounting cavity, wherein the piston block and the piston groove are slidably engaged.

[0013] This utility model has the following beneficial effects:

[0014] 1. This pharmaceutical friability testing instrument, through the setting of a moving mechanism, places the medicine inside the second mounting cavity. The servo motor is activated, driving the rotating shaft and the turntable outside the shaft to rotate. The fixed column slides and engages with the slide groove, causing the rotating block to swing. The first and second teeth mesh and drive the moving column to reciprocate, causing the extrusion plate to extrude the medicine. The extrusion force of the extrusion plate is controlled by controlling the speed of the servo motor. The servo motor has high-precision speed and position control capabilities, enabling fine adjustments to ensure consistent extrusion force each time. This solves the problem that if the medicine does not have hardness testing, breakage or wear during storage or transportation may lead to increased exposure of drug components, thus affecting the stability and safety of the drug.

[0015] 2. This pharmaceutical friability testing instrument utilizes a piston block design. The piston block engages with the piston groove, ensuring stable movement of the extrusion plate as it compresses the drug. This prevents inaccurate drug testing due to unstable movement. The interaction between the piston block and the piston groove precisely controls the movement path of the extrusion plate, ensuring stable vertical movement. This stable movement avoids uneven compression force caused by plate misalignment or vibration, thereby improving the compression effect and testing accuracy. Attached Figure Description

[0016] Figure 1 This is a three-dimensional structural diagram of the present invention.

[0017] Figure 2 This is a schematic diagram of the moving mechanism structure of this utility model.

[0018] Figure 3 This is a cross-sectional structural diagram of the present invention.

[0019] Figure 4 This is a schematic diagram of the piston groove structure of this utility model.

[0020] In the diagram: 110, First mounting box; 111, First mounting cavity; 112, Servo motor; 113, Rotating shaft; 114, Turntable; 120, Second mounting box; 121, Second mounting cavity; 122, Extrusion plate; 140, Moving mechanism; 141, Clamping plate; 142, Moving column; 143, Slide groove; 144, Fixed column; 145, Rotating block; 150, First tooth; 151, Snap ring; 152, Second tooth; 153, Piston block; 154, Piston groove. Detailed Implementation

[0021] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0022] Example 1: This example aims to address the issue that if a drug lacks hardness testing, breakage or abrasion during storage or transportation may lead to increased exposure of drug components, thereby affecting the drug's stability and safety. Please refer to [link to example]. Figure 1-4 A pharmaceutical manufacturing friability testing instrument includes a first mounting box 110 and a second mounting box 120. The first mounting box 110 is located at the end of the second mounting box 120. The first mounting box 110 has a first mounting cavity 111 inside, and the second mounting box 120 has a second mounting cavity 121 inside. A moving mechanism 140 is provided inside the first mounting cavity 111.

[0023] A pressing plate 122 is disposed inside the second mounting cavity 121, and the moving mechanism 140 cooperates with the pressing plate 122. A servo motor 112 is connected to the side of the first mounting box 110, and the output shaft of the servo motor 112 passes through the side of the first mounting box 110. A rotating shaft 113 is connected to the inner wall of the first mounting cavity 111, and a turntable 114 is sleeved on the outer side of the rotating shaft 113. The output shaft of the servo motor 112 is keyed to the rotating shaft 113. The moving mechanism 140 includes a locking plate 141 and a moving column 142, which are disposed inside the first mounting cavity 111.

[0024] The locking plate 141 has a sliding groove 143 on its side, and a fixed post 144 is connected to the side of the rotating disk. The fixed post 144 and the sliding groove 143 are slidably engaged. A rotating block 145 is connected to the end of the locking plate 141. Several first teeth 150 are connected to the side of the rotating block 145. A retaining ring 151 is connected to the inner wall of the first mounting cavity 111. A moving post 142 is inserted into the inside of the retaining ring 151. A second tooth 152 is connected to the side of the moving post 142. The first teeth 150 and the second teeth 152 mesh and drive each other. The moving post 142 is connected to the side of the extrusion plate 122.

[0025] In this embodiment: the medicine is placed inside the second mounting cavity 121 by setting the moving mechanism 140. The servo motor 112 is started, and the servo motor 112 drives the rotating shaft 113 and the turntable 114 outside the rotating shaft 113 to rotate. The fixed column 144 slides and engages with the slide groove 143, causing the rotating block 145 to swing. The first tooth 150 and the second tooth 152 mesh and drive the moving column 142 to reciprocate, causing the extrusion plate 122 to extrude the medicine. The extrusion force of the extrusion plate 122 on the medicine is controlled by controlling the rotation speed of the servo motor 112. The servo motor 112 has high-precision speed and position control capabilities, which can achieve fine adjustment and ensure that the extrusion force is consistent each time. This solves the problem that if the medicine is not tested for hardness, it may break or wear during storage or transportation, which may lead to increased exposure of drug components and thus affect the stability and safety of the medicine.

[0026] Example 2 aims to address the problem of unstable extrusion. This example is an improvement upon Example 1. For details, please refer to [link / reference]. Figure 1-4 A piston block 153 is connected to the side of the extrusion plate 122, and a piston groove 154 is provided on the inner wall of the second mounting cavity 121. The piston block 153 and the piston groove 154 are slidably engaged.

[0027] In this embodiment, the piston block 153 is configured to cooperate with the piston groove 154. While the extrusion plate 122 extrudes the drug, the piston block 153 and piston groove 154 slide and engage, ensuring stable movement of the extrusion plate 122. This prevents inaccurate drug detection due to unstable movement. The cooperation between the piston block 153 and piston groove 154 precisely controls the movement path of the extrusion plate 122, ensuring stable vertical movement. This stable movement avoids uneven extrusion force caused by offset or vibration of the extrusion plate 122, thereby improving the extrusion effect and detection accuracy of the drug.

[0028] It should be noted that, in this document, relational terms such as "first" and "second" are used only to distinguish one entity or operation from another, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Furthermore, the terms "comprising," "including," or any other variations thereof are intended to cover non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements includes not only those elements but also other elements not expressly listed, or elements inherent to such process, method, article, or apparatus.

[0029] The above description is only a preferred embodiment of the present utility model. It should be noted that for those skilled in the art, several improvements and modifications can be made without departing from the technical principles of the present utility model, and these improvements and modifications should also be considered within the protection scope of the present utility model.

Claims

1. A pharmaceutical production friability tester comprising a first mounting box (110) and a second mounting box (120), the first mounting box (110) being disposed at an end of the second mounting box (120), characterized in that: The first installation box (110) is internally provided with a first installation cavity (111), the second installation box (120) is internally provided with a second installation cavity (121), and the first installation cavity (111) is internally provided with a moving mechanism (140).

2. A pharmaceutical production friability tester according to claim 1, wherein: The second installation cavity (121) is internally provided with an extrusion plate (122), and the moving mechanism (140) is used in cooperation with the extrusion plate (122).

3. A pharmaceutical production friability tester according to claim 2, wherein: The first installation box (110) is connected with a servo motor (112) on the side, and the output shaft of the servo motor (112) penetrates the side of the first installation box (110).

4. A pharmaceutical production friability tester according to claim 3, wherein: The first installation cavity (111) is connected with a rotating shaft (113) on the inner wall, the rotating shaft (113) is externally sleeved with a rotating disc (114), and the output shaft of the servo motor (112) is connected with the rotating shaft (113) in a key connection mode.

5. A pharmaceutical production friability tester according to claim 4, wherein: The moving mechanism (140) comprises a clamping plate (141) and a moving column (142), and the clamping plate (141) and the moving column (142) are arranged in the first installation cavity (111).

6. A pharmaceutical production friability tester according to claim 5, wherein: The clamping plate (141) is connected with a rotating block (145) at the end, a plurality of first teeth (150) are connected on the side of the rotating block (145), a clamping ring (151) is connected on the inner wall of the first installation cavity (111), the moving column (142) is inserted into the clamping ring (151), a second tooth (152) is connected on the side of the moving column (142), the first tooth (150) is in meshing transmission with the second tooth (152), and the moving column (142) is connected on the side of the extrusion plate (122).

7. A pharmaceutical production friability tester according to claim 5, wherein: The extrusion plate (122) is connected with a piston block (153) on the side, the second installation cavity (121) is internally provided with a piston groove (154), and the piston block (153) is in sliding clamping connection with the piston groove (154).

8. A pharmaceutical production friability tester according to claim 7, wherein: ​

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