Elastic heating device

Abstract

The utility model relates to the technical field of molecular biology, in particular to an elastic heating device. The utility model provides an elastic heating device which enables PCR consumables to be tightly attached to a heating plate when a PCR instrument is used for an experiment, improves the heating effect of the PCR consumables and ensures the accuracy of an experiment result. An elastic heating device comprises a heating cover, a fixing frame, guide columns and the like, the fixing frame is connected to the top in the heating cover, and the left guide column and the right guide column are slidably connected to the front portion and the rear portion of the fixing frame. According to the utility model, the heating block and the PCR consumables can be extruded while the heating plate is closed, so that the spring is contracted, and the heating block is tightly pressed on the PCR consumables under the counter-acting force of the spring, so that the effects that the PCR consumables can be tightly attached to the heating plate, the heating effect of the PCR consumables is improved and the accuracy of experimental results is ensured when a PCR instrument is used for an experiment are achieved.

Description

Technical Field

[0001] This invention relates to the field of molecular biology technology, and in particular to an elastic heating device. Background Technology

[0002] In the PCR reaction, the DNA double strand separates into single strands in the denaturation step, then the primers bind to the target region of the DNA template in the annealing step, and finally the DNA polymerase extends the primers by adding new nucleotides in the extension step, synthesizing new DNA strands. The PCR experiment is usually equipped with a heating device to control the temperature.

[0003] The heating devices for consumables in existing PCR experiments (e.g., CN119177164A) are usually located on the top cover of the PCR instrument. After the PCR consumables are placed inside the cavity of the PCR instrument, the heating device comes into contact with the PCR consumables by closing the top cover of the PCR instrument, and heats the DNA sample inside the PCR consumables. However, because the heating devices on existing PCR instruments have a fixed structure, the heating device cannot fit tightly against the PCR consumables, which may result in poor heating effect or sample evaporation, affecting the accuracy of experimental results and causing inconvenience.

[0004] Therefore, a flexible heating device has been developed that allows PCR consumables to adhere tightly to the heating plate during PCR experiments, thereby improving the heating effect of the PCR consumables and ensuring the accuracy of experimental results. Utility Model Content

[0005] To overcome the shortcomings of existing PCR instruments where the heating device is a fixed structure, which prevents the heating device from fitting tightly to the PCR consumables, potentially leading to poor heating or sample evaporation and affecting the accuracy of experimental results, this invention provides a flexible heating device that allows the PCR consumables to fit tightly against the heating plate during PCR experiments, improving the heating effect of the PCR consumables and ensuring the accuracy of experimental results.

[0006] The technical solution of this utility model is as follows:

[0007] An elastic heating device includes a heating cover, a fixing frame, guide posts, a heating block, retaining rings, springs, a heating film, and an annealing assembly. The fixing frame is connected to the top of the heating cover. Two guide posts are slidably connected to the front and rear of the fixing frame. A heating block is connected between the lower sides of the guide posts. Springs are connected between the guide posts and the fixing frame. Two retaining rings are connected to the front and rear of the upper side of the fixing frame. The retaining rings are in contact with the adjacent guide posts. A heating film is connected to the upper side of the heating block. The guide posts pass through the heating film. An annealing assembly capable of uniformly annealing PCR consumables is provided inside the heating cover.

[0008] In one embodiment, the device further includes a switch and a blocking rod. The switch is connected to the upper side of the middle portion of the heating film, and the blocking rod is connected to the middle portion of the fixing frame. The blocking rod is in a pressing fit with the switch.

[0009] In one embodiment, the annealing assembly includes an oil tank, an oil pump, hoses, and a cooling pipe. The oil tank is connected to the right side of the heating cover, the oil pump is connected to the front left side of the oil tank, hoses are connected to the left sides of both the front and rear sides of the oil tank, the front hose is connected to the oil pump, and the cooling pipe is connected inside the heating block. The hoses are connected to the cooling pipe.

[0010] In one embodiment, a heat dissipation fin is also included, with the heat dissipation fin connected to the right side of the oil tank.

[0011] In one embodiment, the heating cover is further provided with a mounting plate and a fan, with the mounting plate connected to the right side of the heating cover and the fan rotatably connected to the right side of the middle of the mounting plate.

[0012] In one embodiment, an air inlet is provided on the mounting plate.

[0013] Beneficial effects: 1. When the device is closed, the heating block and PCR consumables are squeezed together, causing the spring to contract. Under the reaction force of the spring, the heating block is pressed tightly onto the PCR consumables. This achieves the effect of keeping the PCR consumables in close contact with the heating plate when conducting experiments with the PCR instrument, improving the heating effect of the PCR consumables and ensuring the accuracy of experimental results.

[0014] 2. This utility model activates an oil pump, which draws cooling oil from inside the oil tank into the cooling pipe for circulation, cooling the heating block. Then, the fan on the mounting plate is activated to cool the heat sink fins, improving the cooling efficiency of PCR consumables. This allows for uniform cooling of PCR consumables, improving the efficiency and accuracy of PCR experiments. Attached Figure Description

[0015] Figure 1 This is a three-dimensional structural diagram of the present invention.

[0016] Figure 2 This is a cross-sectional view of the structure of this utility model.

[0017] Figure 3 This is a three-dimensional structural diagram of the fixing frame and guide column components of this utility model.

[0018] Figure 4 This is a three-dimensional structural diagram of the switch and stop bar components of this utility model.

[0019] Figure 5 This is a three-dimensional structural diagram of the oil tank and oil pump components of this utility model.

[0020] Figure 6 This is a three-dimensional structural diagram of the hose and cooling pipe components of this utility model.

[0021] The markings in the diagram are explained as follows:

[0022] 1- Heating cover;

[0023] 2-Fixed bracket;

[0024] 3-Guide pillars;

[0025] 4-Heating block;

[0026] 5-Snap ring;

[0027] 6-Spring;

[0028] 7-Heating film;

[0029] 8-Switch;

[0030] 9-Blocking bar;

[0031] 10-Fuel tank;

[0032] 11-Oil pump;

[0033] 12-Hose;

[0034] 13-Cooling pipe;

[0035] 14-Heat dissipation fins;

[0036] 15-Mounting plate;

[0037] 16- Fan. Detailed Implementation

[0038] The present invention will be further described below with reference to the embodiments shown in the accompanying drawings.

[0039] A flexible heating device, such as Figures 1-6As shown, the device includes a heating cover 1, a fixing frame 2, guide posts 3, a heating block 4, retaining rings 5, springs 6, a heating film 7, a switch 8, a blocking rod 9, an oil tank 10, an oil pump 11, a hose 12, a cooling pipe 13, heat dissipation fins 14, a mounting plate 15, and a fan 16. The fixing frame 2 is connected to the top of the heating cover 1. Two guide posts 3 are slidably connected to the front and rear of the fixing frame 2. A heating block 4 is connected between the lower sides of the guide posts 3. Springs 6 connect each guide post 3 to the fixing frame 2. Two retaining rings 5 ​​are connected to the front and rear of the upper side of the fixing frame 2, and each retaining ring 5 contacts and engages with the adjacent guide post 3. A heating film 7 is connected to the upper side of the heating block 4. Guide pillars 3 all pass through heating film 7. Switch 8 is connected to the upper middle part of heating film 7. Blocking rod 9 is connected to the middle of fixing bracket 2. Blocking rod 9 and switch 8 are pressed together. Oil tank 10 is connected to the right side of heating cover 1. Oil pump 11 is connected to the front left of oil tank 10. Hose 12 is connected to the left side of both front and rear parts of oil tank 10. Hose 12 at the front is connected to oil pump 11. Cooling pipe 13 is connected inside heating block 4. Hose 12 is connected to cooling pipe 13. Heat sink fins 14 are connected to the right side of oil tank 10. Mounting plate 15 is connected to the right side of heating cover 1. Fan 16 is rotatably connected to the right side of the middle of mounting plate 15. Air inlet is opened on mounting plate 15 for ventilation and heat dissipation.

[0040] When using this invention, firstly, the heating cover 1 is installed and fixed inside the upper cover of the PCR instrument. During the PCR experiment, the PCR consumables containing the experimental samples are placed inside the cavity of the PCR instrument. The upper cover of the PCR instrument is then rotated and closed. Simultaneously, the heating block 4 is compressed against the PCR consumables, causing the spring 6 to contract. Under the reaction force of the spring 6, the heating block 4 is pressed firmly against the PCR consumables. While the PCR instrument is pressing the consumables, the heating block 4 is also pushed upwards, causing the switch 8 to move upwards and contact the blocking rod 9. The blocking rod 9 then opens the switch 8, controlling the heating film 7 to heat up. This allows the heating block 4 to heat the PCR consumables evenly, thus achieving the desired effect. When conducting experiments using a PCR instrument, ensuring the PCR consumables are in close contact with the heating plate enhances the heating effect and ensures the accuracy of experimental results. Spring 6 limits the guide post 3. After heating, oil pump 11 can be activated to draw cooling oil from inside the oil tank 10 through hose 12 into the cooling pipe 13 for circulation, cooling the heating block 4 and thus annealing the PCR consumables. The cooling oil is cooled by heat sink 14, and the fan 16 on the mounting plate 15 further cools the heat sink 14, improving the cooling efficiency of the PCR consumables and ensuring uniform cooling, thereby improving the efficiency and accuracy of PCR experiments.

[0041] The embodiments of the present invention have been described in detail above with reference to the accompanying drawings. However, the present invention is not limited to the above embodiments. Within the scope of knowledge possessed by those skilled in the art, various changes can be made without departing from the spirit of the present invention.

Claims

1. A flexible heating device, characterized in that, include: Heating cover (1), fixing bracket (2), guide post (3), heating block (4), retaining ring (5), spring (6), heating film (7) and annealing assembly; The top of the heating cover (1) is connected to a fixed frame (2); the front and rear parts of the fixed frame (2) are slidably connected to two left and right guide pillars (3), and the guide pillars (3) are connected to the fixed frame (2) by springs (6); the front and rear parts of the upper side of the fixed frame (2) are connected to two left and right retaining rings (5), and the retaining rings (5) are in contact with the adjacent guide pillars (3); A heating block (4) is connected between the lower sides of the guide column (3), and a heating film (7) is connected to the upper side of the heating block (4); the guide column (3) passes through the heating film (7), and the heating cover (1) is equipped with an annealing component that can uniformly anneal PCR consumables.

2. The elastic heating device as described in claim 1, characterized in that: It also includes a switch (8) and a blocking rod (9). The switch (8) is connected to the upper side of the middle part of the heating film (7), and the blocking rod (9) is connected to the middle part of the fixing frame (2). The blocking rod (9) and the switch (8) are pressed together.

3. The elastic heating device as described in claim 1, characterized in that: The annealing assembly includes an oil tank (10), an oil pump (11), a hose (12), and a cooling pipe (13). The right side of the heating cover (1) is connected to the oil tank (10), the front left side of the oil tank (10) is connected to the oil pump (11), the left and right sides of the oil tank (10) are connected to the hose (12), the front hose (12) is connected to the oil pump (11), the inside of the heating block (4) is connected to the cooling pipe (13), and the hose (12) is connected to the cooling pipe (13).

4. The elastic heating device as described in claim 3, characterized in that: It also includes heat dissipation fins (14), and the right side of the oil tank (10) is connected to the heat dissipation fins (14).

5. The elastic heating device as described in claim 4, characterized in that: It also includes a mounting plate (15) and a fan (16). The mounting plate (15) is connected to the right side of the heating cover (1), and the fan (16) is rotatably connected to the right side of the middle part of the mounting plate (15).

6. The elastic heating device as described in claim 5, characterized in that: An air inlet is provided on the mounting plate (15).

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