Magnetic separation frame

Abstract

The utility model discloses a magnetic separation frame which comprises a magnetic plate, a pipe frame and a base, a rotating mechanism for driving the magnetic plate to rotate is arranged on the base, and the pipe frame is movably connected with the magnetic plate. In the magnetic bead separation process of the sample tube, the rotating mechanism is additionally arranged on the base, and the tube frame and the magnetic plate are designed to be of a detachable connection structure, so that the magnetic frame has the characteristics that the installation is simple, waste liquid is convenient to pour, and a large number of samples can be quickly treated.

Description

Technical Field

[0001] This utility model relates to a separation rack, and more particularly to a magnetic separation rack. Background Technology

[0002] Biomagnetic beads have demonstrated wide-ranging applications in various fields, including medical diagnostics, environmental monitoring, nucleic acid preparation, immunoassay, biotin capture, fluorescent labeling, protein purification, exosome isolation, and target identification. In these applications, magnetic separation technology serves as a key method, efficiently collecting biomagnetic beads through magnetic force. Specifically, samples containing magnetic particles are carefully placed on a magnetic separation rack, where the magnetic particles are firmly adsorbed by magnetic force, thus easily achieving precise separation from non-magnetic media. However, existing magnetic separation technologies present several problems when using multiple sample tubes for magnetic bead experiments. On the one hand, when using a single magnetic rack, the shaken sample tubes must be removed one by one from the sample tube rack and then placed on the magnetic rack for magnetic separation. During this process, waste liquid in the sample tubes must also be removed by aspirating each tube individually. This method is not only inefficient but also cumbersome, making it difficult to meet the needs of rapidly processing large numbers of samples. On the other hand, while modular magnetic racks simplify the operation to some extent, allowing the entire test tube rack to be directly mounted on the magnetic rack, thus eliminating the need for individual test tube installation, they still present numerous challenges. However, when it is necessary to pour out the waste liquid in the test tube, the operator needs to lift and tilt the entire magnetic rack. This operation not only poses a safety hazard and is prone to damaging the equipment, but is also extremely inconvenient in actual operation, seriously affecting work efficiency and the accuracy of experimental results. Utility Model Content

[0003] Purpose of the utility model: The purpose of this utility model is to provide a magnetic separation rack that is easy to install, convenient to pour out waste liquid, and can quickly process a large number of samples.

[0004] Technical solution: The magnetic separation frame of this utility model includes a magnetic plate, a tube frame and a base. The base is provided with a rotating mechanism that drives the magnetic plate to rotate. The tube frame is movably connected to the magnetic plate.

[0005] Preferably, the rotating mechanism consists of a rotating shaft and a rotating control component, with a magnetic plate fixed on the rotating shaft and the rotating control component used to control the rotation of the rotating shaft.

[0006] Preferably, the tube rack has a slot in the middle, through which the tube rack engages with the magnetic plate.

[0007] Preferably, the rotation control component is provided with a limiting component to limit the rotation range of the rotation shaft.

[0008] Preferably, the tube rack is provided with clamping pins on both sides, and the magnetic plate is provided with corresponding first slots on both sides. The clamping pins cooperate with the first slots to fix the tube rack and the magnetic plate in place.

[0009] Preferably, the tube rack has one or more tube holes and a locking device for fixing the sample tube inside the tube hole.

[0010] Preferably, the locking device consists of a pressure plate and a hand screw, the hand screw presses the pressure plate to adjust the size of the tube hole, and the inner wall of the tube hole has an elastic structure.

[0011] Beneficial effects: Compared with the prior art, the present invention has the following advantages: By adding a rotating mechanism to the base during the separation of magnetic beads in the sample tube, and designing the tube rack and magnetic plate as a detachable connection structure, the present invention makes the magnetic rack easy to install, convenient to pour out waste liquid, and able to quickly process a large number of samples. Attached Figure Description

[0012] Figure 1 This is a schematic diagram of the overall magnetic separation frame of this utility model.

[0013] Figure 2 This is a schematic diagram of the base of this utility model.

[0014] Figure 3 This is a schematic diagram of the rotation control component of this utility model.

[0015] Figure 4 This is a schematic diagram of the pipe rack structure of this utility model.

[0016] Figure 5 This is a schematic diagram of the magnetic plate structure of this utility model. Detailed Implementation

[0017] The technical solution of this utility model will be further described below with reference to the accompanying drawings.

[0018] like Figure 1-5As shown, a magnetic separation frame includes a magnetic plate 1, a tube rack 2, and a base 3. The base 3 is equipped with a rotating mechanism consisting of a rotating shaft 4 and a rotating control component 5. The magnetic plate 1 is fixedly mounted on the rotating shaft 4, which drives the magnetic plate 1 to rotate. The rotating control component 5 controls the rotation of the rotating shaft 4, thereby adjusting the rotation angle of the magnetic plate 1. Rotating the rotating control component 5 clockwise allows the rotating shaft 4 to rotate. When the magnetic plate 1 reaches the desired tilt angle, rotating the rotating control component 5 counterclockwise locks the rotating shaft 4, preventing further rotation. Simultaneously, the rotating control component 5 is equipped with a limiting component 12 to restrict the rotation range of the rotating shaft 4, thus achieving precise control of the rotation angle of the magnetic plate 1. This design can meet the specific requirements for the rotation angle of the magnetic plate 1 in different experiments or operations, improving the accuracy and stability of the experiments or operations. A slot 11 is provided in the middle of the tube rack 2, through which the tube rack 2 engages with the magnetic plate 1. The tube rack 2 has clamping pins 6 on both sides, which engage with the first slots 7 on both sides of the magnetic plate 1 to fix the tube rack 2 onto the magnetic plate 1. This design allows the tube rack 2 to be fixed or adjusted relative to the magnetic plate 1 as needed. Specifically, by pulling the clamping pins 6 outward, placing the tube rack 2 into the magnetic plate 1 until it reaches the slot 11, and then pressing the clamping pins 6 inward, the clamping pins 6 engage with the first slots 7 on the magnetic plate 1, preventing the sample tube rack 2 from falling off. The tube rack 2 has multiple tube holes 8, and the inner wall of the tube holes 8 has an elastic structure. This design can better accommodate sample tubes of different diameters, improving the flexibility and convenience of use. At the same time, the tube rack 2 is also equipped with a locking device for fixing the sample tubes in the tube holes 8. The locking device consists of a pressure plate 9 and a hand screw 10. The hand screw 10 presses the pressure plate 9 to adjust the size of the tube holes 8.

[0019] The working principle of the entire device is as follows: Place the sample tube into the tube hole 8 on the tube rack 2, and rotate the hand screw 10 to firmly fix the sample tube. The tube rack 2 with the sample tube is engaged with the magnetic plate 1 through the slot 11, and the clamping pin 6 is pressed inward to make the clamping pin 6 engage with the first slot 7 on the magnetic plate 1, thus preventing the sample tube rack 2 from falling off. Rotate the control component 5 clockwise, and the rotating shaft 4 will drive the magnetic plate 1 to rotate. When the magnetic plate 1 reaches the desired tilt angle, rotate the control component 5 counterclockwise, and the rotating shaft 4 will lock, stopping the rotation and allowing all the liquid in the sample tube to be poured out without manual emptying. After all the waste liquid is discharged, rotate the control component 5 clockwise again, and the rotating shaft 4 will drive the magnetic plate 1 to rotate, making the magnetic plate 1 and the tube holder 2 rotate to a vertical position. After reaching the desired tilt angle, rotate the control component 5 counterclockwise, and the rotating shaft 4 will lock, stopping the rotation. Pull out the clamping pin 6 to remove the tube holder 2 from the magnetic plate 1. Then, rotate the hand screw 10 in the opposite direction to remove the sample tube from the tube holder 2, completing the subsequent magnetic bead collection. Since the sample tube holder 2, magnetic plate 1, and base 3 can be combined, different sample tube holders 2 can be replaced according to the actual situation to meet the needs of sample tubes of different specifications, improving the versatility of the sample tubes.

Claims

1. A magnetic separation frame, comprising a magnetic plate (1), a tube rack (2), and a base (3), characterized in that: The base (3) is provided with a rotating mechanism that drives the magnetic plate (1) to rotate, and the tube frame (2) is movably connected to the magnetic plate (1).

2. The magnetic separator according to claim 1, characterized in that: The rotating mechanism consists of a rotating shaft (4) and a rotating control component (5). The magnetic plate (1) is fixed on the rotating shaft (4), and the rotating control component (5) is used to control the rotation of the rotating shaft (4).

3. The magnetic separator according to claim 1, characterized in that: The pipe rack (2) is provided with a slot (11) in the middle, and the pipe rack (2) is engaged with the magnetic plate (1) through the slot (11).

4. The magnetic separator according to claim 2, characterized in that: The rotation control component (5) is provided with a limiting component (12) to limit the rotation range of the rotation shaft (4).

5. The magnetic separator according to claim 1, characterized in that: The tube rack (2) is provided with clamping pins (6) on both sides, and the magnetic plate (1) is provided with corresponding first slots (7) on both sides. The clamping pins (6) and the first slots (7) cooperate to fix the tube rack (2) and the magnetic plate (1) in place.

6. The magnetic separator according to claim 1, characterized in that: The tube rack (2) has one or more tube holes (8) and a locking device for fixing the sample tube inside the tube hole (8).

7. The magnetic separator according to claim 6, characterized in that: The locking device consists of a pressure plate (9) and a hand screw (10). The hand screw (10) presses the pressure plate (9) to adjust the size of the tube hole (8). The inner wall of the tube hole (8) is an elastic structure.

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