Fusion protein preservation device

Abstract

The utility model discloses a fusion protein storage device, which belongs to the technical field of fusion protein storage devices, and is characterized by comprising a storage component, and a cooling component is slidably connected into the storage component; the cooling assembly comprises a drawing hole, an ice block storage box is slidably connected into the drawing hole, a top plate is slidably connected to the top of the ice block storage box, a mounting hole is formed in the top of the top plate, a conical block is clamped into the mounting hole, and a circular pipe communicates with the interior of the conical block. A sealing groove is formed in the front side of the drawing hole, a sealing block matched with the sealing groove for use is fixedly connected to the front side of the ice block storage box, and the problems that most existing fusion protein storage devices are of fixed structures, under some special conditions, protein needs to be transferred, most existing transfer is achieved through a simple sealed storage box, and operation is inconvenient can be solved. The long-time storage of the protein is inconvenient.

Description

Technical Field

[0001] This utility model relates to the technical field of fusion protein preservation devices, and in particular to a fusion protein preservation device. Background Technology

[0002] Fusion proteins are recombinant proteins formed by linking proteins encoded by two or more genes together using genetic engineering techniques. In the field of biopharmaceuticals, many therapeutic antibodies and cytokines are fusion proteins. For example, immune checkpoint inhibitors used to treat cancer are formed by fusing antibody fragments with specific proteins to enhance their targeting and efficacy.

[0003] To address the aforementioned issues, existing patents offer solutions. Most existing fusion protein preservation devices are fixed structures. In some special cases, protein transfer is required. Existing transfer devices are mostly simple sealed storage boxes, which are not convenient for long-term protein storage.

[0004] To address this, a device for preserving fusion proteins is proposed. Utility Model Content

[0005] The purpose of this invention is to provide a fusion protein preservation device that solves the problem that most existing fusion protein preservation devices have a fixed structure. In some special cases, it is necessary to transfer the protein, and most existing transfer devices are simple sealed storage boxes, which are not convenient for long-term protein storage.

[0006] To achieve the above objectives, the present invention provides the following technical solution: a fusion protein preservation device, comprising a storage component, wherein a cooling component is slidably connected inside the storage component;

[0007] The cooling assembly includes a pull-out hole, an ice storage box is slidably connected inside the pull-out hole, a top plate is slidably connected to the top of the ice storage box, a mounting hole is opened on the top of the top plate, a conical block is snapped into the mounting hole, a circular tube is connected inside the conical block, a sealing groove is opened on the front side of the pull-out hole, a sealing block that cooperates with the sealing groove is fixedly connected to the front side of the ice storage box, and an adjustment handle is fixedly connected to the front side of the sealing block.

[0008] Preferably, the storage component includes a box, a top cover is rotatably connected to the top of the box, a frame is fixedly connected inside the box, a storage box is snapped into the inside of the frame, a shelf is fixedly connected inside the storage box, and a protective cover is snapped into the top of the storage box.

[0009] Preferably, the storage component includes a box, a top cover is rotatably connected to the top of the box, a frame is fixedly connected inside the box, a storage box is snapped into the inside of the frame, a shelf is fixedly connected inside the storage box, and a protective cover is snapped into the top of the storage box.

[0010] Preferably, the top of the box body is provided with a slot, and the bottom of the top cover is fixedly connected with a card block that cooperates with the slot, and a soft pad is fixedly connected inside the card block.

[0011] Preferably, the storage box has snap-fit ​​slots on both the left and right sides, a protective sleeve on the surface of the storage box, and snap-fit ​​blocks that cooperate with the snap-fit ​​slots are fixedly connected to the left and right sides of the inner wall of the protective sleeve. Both the protective sleeve and the snap-fit ​​blocks are made of aluminum alloy.

[0012] Preferably, the bottom of the box is provided with a placement groove, and an anti-slip pad is engaged inside the placement groove. The anti-slip pad is made of silicone.

[0013] Preferably, the bottom of the box is provided with a placement groove, and an anti-slip pad is engaged inside the placement groove. The anti-slip pad is made of silicone.

[0014] Preferably, a fixing rod is fixedly connected to the front side of the box, and a limit block is rotatably connected to the surface of the fixing rod.

[0015] Compared with the prior art, the beneficial effects of this utility model are:

[0016] 1. In this application, the ice storage box in the cooling component is used to store ice, thereby reducing the internal temperature of the storage component and providing a low-temperature preservation environment for the fusion protein. This allows the cold air to diffuse more evenly into the storage component, ensuring that the fusion protein is in a stable low-temperature state and reducing the impact of temperature fluctuations on protein activity.

[0017] 2. This application effectively blocks the entry of external hot air, dust and moisture, maintains a low temperature and clean internal environment, reduces the impact of external factors on the fusion protein, and extends the storage time of the fusion protein. Attached Figure Description

[0018] Figure 1 This is an overall structural diagram of the fusion protein preservation device of this utility model;

[0019] Figure 2 This is a schematic diagram of the cooling component of this utility model;

[0020] Figure 3 This is a schematic diagram of the structure of the storage component of this utility model;

[0021] Figure 4This is a disassembled schematic diagram of the protective sleeve and storage box of this utility model;

[0022] Figure 5 This is a disassembled schematic diagram of the placement groove and anti-slip mat of this utility model.

[0023] In the diagram, 1. Storage component; 101. Box body; 102. Top cover; 103. Frame; 104. Storage box; 105. Display rack; 106. Protective cover; 107. Protective groove; 108. Protective block; 109. Card slot; 110. Card block; 111. Soft pad; 2. Cooling component; 201. Pull-out hole; 202. Ice storage box; 203. Top plate; 204. Mounting hole; 205. Conical block; 206. Circular tube; 207. Sealing groove; 208. Sealing block; 209. Adjustment handle; 3. Snap-fit ​​groove; 4. Protective sleeve; 5. Snap-fit ​​block; 6. Placement groove; 7. Anti-slip pad; 8. Groove; 9. Adjustment rack; 10. Anti-slip plate; 11. Fixing rod; 12. Limiting block. Detailed Implementation

[0024] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0025] Please see Figure 1-5 The present invention provides the following technical solution:

[0026] A fusion protein preservation device includes a storage component 1, and a cooling component 2 is slidably connected inside the storage component 1;

[0027] The cooling assembly 2 includes a pull-out hole 201, an ice storage box 202 is slidably connected inside the pull-out hole 201, a top plate 203 is slidably connected to the top of the ice storage box 202, a mounting hole 204 is provided on the top of the top plate 203, a conical block 205 is snapped into the mounting hole 204, a circular tube 206 is connected inside the conical block 205, a sealing groove 207 is provided on the front side of the pull-out hole 201, a sealing block 208 that cooperates with the sealing groove 207 is fixedly connected to the front side of the ice storage box 202, and an adjustment handle 209 is fixedly connected to the front side of the sealing block 208.

[0028] In this embodiment: A storage component 1 is provided to house test tubes containing mixed proteins. It works in conjunction with a cooling component 2 to maintain a constant temperature inside the storage component 1, ensuring the mixed proteins inside the test tubes are stored at a constant temperature. A pull-out hole 201, an ice storage box 202, a top plate 203, a mounting hole 204, a conical block 205, a circular tube 206, a sealing groove 207, and a sealing block 208 are provided, along with an adjustment handle 209. The pull-out hole 201 allows the ice storage box 202 to be connected to the storage component 1. The ice storage box 202 stores ice. The top plate 203 allows for ventilation of the top of the ice storage box 202. The ice storage box 202 is shielded by a mounting hole 204, which allows the conical block 205 to communicate with the top plate 203. The conical block 205 and the circular tube 206 allow the gas inside the ice storage box 202 to be supplied to the interior of the storage component 1. The shape of the conical block 202 and the circular tube 206 prevents the liquid from melting ice from splashing into the interior of the storage component 1. The sealing groove 207 and the sealing block 208 work together to improve the sealing at the connection between the ice storage box 202 and the pull hole 201. The handle 209 allows the user to manually pull the ice storage box 202 out of the pull hole 201.

[0029] Specifically, such as Figure 3 As shown, the storage component 1 includes a housing 101, a top cover 102 rotatably connected to the top of the housing 101, a frame 103 fixedly connected inside the housing 101, a storage box 104 snapped into the inside of the frame 103, a display rack 105 fixedly connected inside the storage box 104, and a protective cover 106 snapped into the top of the storage box 104.

[0030] Specifically, such as Figure 3 As shown, a protective groove 107 is provided on the top of the box 101, and a protective block 108 is fixedly connected to the bottom of the top cover 102. The protective block 108 is located inside the protective groove 107, and the side of the protective block 108 away from the top cover 102 is in contact with the inner wall of the protective groove 107.

[0031] Specifically, such as Figure 3 As shown, the top of the box 101 is provided with a slot 109, and the bottom of the top cover 102 is fixedly connected with a block 110 that works with the slot 109. A soft pad 111 is fixedly connected inside the block 110.

[0032] In this embodiment: by setting up a box 101, a top cover 102, a frame 103, a storage box 104, a display rack 105, and a protective cover 106, the box 101 and the top cover 102 can be used together to place the frame 103 and the storage box 104. The frame 103 can support the storage box 104. By setting the storage box 104 and the protective cover 106 to work together, a sealed space is formed. The display rack 105 can be used to place test tubes containing proteins. For storage, the protective groove 107 and protective block 108 can improve the sealing effect at the connection between the top cover 102 and the box body 101. The slot 109, the block 110 and the soft pad 111 can be spliced ​​with the slot 109 to improve the tightness of the connection between the top cover 102 and the box body 101. The soft pad 111 can contact the top of several protective covers 106 and limit the position of several protective covers 106.

[0033] Specifically, such as Figure 4 As shown, the storage box 104 has a snap-fit ​​groove 3 on both the left and right sides. The surface of the storage box 104 is provided with a protective sleeve 4. The left and right sides of the inner wall of the protective sleeve 4 are fixedly connected with snap-fit ​​blocks 5 that cooperate with the snap-fit ​​groove 3. The protective sleeve 4 and the snap-fit ​​blocks 5 are both made of aluminum alloy.

[0034] Specifically, such as Figure 5 As shown, a placement groove 6 is provided at the bottom of the box 101, and an anti-slip pad 7 is inserted inside the placement groove 6. The anti-slip pad 7 is made of silicone.

[0035] In this embodiment: by setting the snap-fit ​​groove 3, the protective sleeve 4 and the snap-fit ​​block 5, the snap-fit ​​block 5 can be spliced ​​with the snap-fit ​​groove 3, so that the protective sleeve 4 comes into contact with the surface of the storage box 104. During the contact process, the snap-fit ​​block 5 comes into contact with the inner wall of the snap-fit ​​groove 3. Then, after the contact is completed, the protective sleeve 4 comes into contact with the cold air inside the box 101, thereby facilitating the conduction of temperature. By setting the placement groove 6 and the anti-slip pad 7, the anti-slip pad 7 can be placed through the placement groove 6, and then the anti-slip pad 7 prevents the box 101 from shifting position.

[0036] Specifically, such as Figure 1 , Figure 2 As shown, a groove 8 is provided on the top of the top cover 102, and an adjustment frame 9 is rotatably connected inside the groove 8. An anti-slip plate 10 is fixedly connected to the front side of the adjustment frame 9.

[0037] Specifically, such as Figure 1 As shown, a fixing rod 11 is fixedly connected to the front side of the housing 101, and a limit block 12 is rotatably connected to the surface of the fixing rod 11.

[0038] In this embodiment: by setting the groove 8, the adjustment frame 9 and the anti-slip plate 10, the user can manually adjust the adjustment frame 9 so that the adjustment frame 9 is adjusted within the inner wall of the groove 8. Then, the user moves the structure. During the manual operation of the adjustment frame 9, the anti-slip plate 10 facilitates the user's operation of the adjustment frame 9. By setting the fixing rod 11 and the limiting block 12, the limiting block 12 can rotate on the surface of the fixing rod 11, and then the limiting block 12 limits the ice storage box 202 inside the pull hole 201.

[0039] Working principle: The user manually removes the top plate 203 from the top of the ice storage box 202, places ice cubes inside the ice storage box 202, and uses the ice cubes as a cooling source to provide a low-temperature environment for the preservation of the fusion protein. The ice storage box 202, filled with ice cubes, is inserted into the housing 101 through the pull-out hole 201, allowing it to connect with the housing 101. During connection, the sealing block 208 on the front of the ice storage box 202 tightly engages with the sealing groove 207 on the front of the pull-out hole 201 of the housing 101. This design effectively increases the temperature and humidity of the ice storage box. The airtight seal between the ice storage box 202 and the housing 101 prevents cold air leakage and ensures cooling effect. After the ice storage box 202 is installed, the cold air inside the ice storage box 202 will be slowly released and moved into the housing 101 through the conical block 205 that is engaged in the mounting hole 204 in the top plate 203 and the circular tube 206 that is connected to it. The design of the conical block 205 and the circular tube 206 can prevent the ice from melting into water and splashing into the housing 101 due to shaking. The inner part of the storage box 101 contacts the protective sleeve 4. Since the protective sleeve 4 is made of aluminum alloy, it has excellent thermal conductivity and can quickly conduct cold air, thereby lowering the temperature inside the storage box 104. This creates a low-temperature storage environment for the fusion protein placed on the shelf 105 of the storage box 104, achieving effective preservation of the fusion protein. All parts of the storage component 1 work together. The box 101 and the top cover 102 cooperate to protect and fix the frame 103 and the storage box 104. The frame 103 supports the storage box 104, facilitating storage. Box 104 and protective cover 106 work together to form a relatively sealed space, reducing the impact of external factors on the fusion protein. The rack 105 is used to orderly place test tubes containing the fusion protein for easy access and management. The protective groove 107 on the top of the box 101 and the protective block 108, slot 109 and locking block 110 on the bottom of the top cover 102 work together to further enhance the sealing of the device. The soft pad 111 inside the locking block 110 not only increases the sealing but also limits the position of several protective covers 106 to prevent them from shaking.

[0040] The above are merely preferred embodiments of the present utility model and are not intended to limit the present utility model. Any modifications, equivalent substitutions, and improvements made within the spirit and principles of the present utility model should be included within the protection scope of the present utility model.

Claims

1. A fusion protein preservation device, comprising a storage component (1), characterized in that: The storage component (1) is internally slidably connected to a cooling component (2); The cooling assembly (2) includes a pull-out hole (201), an ice storage box (202) is slidably connected inside the pull-out hole (201), a top plate (203) is slidably connected to the top of the ice storage box (202), an installation hole (204) is provided on the top of the top plate (203), a conical block (205) is snapped into the installation hole (204), a circular tube (206) is connected to the inside of the conical block (205), a sealing groove (207) is provided on the front side of the pull-out hole (201), a sealing block (208) that cooperates with the sealing groove (207) is fixedly connected to the front side of the ice storage box (202), and an adjustment handle (209) is fixedly connected to the front side of the sealing block (208).

2. The fusion protein preservation device according to claim 1, characterized in that: The storage component (1) includes a box (101), a top cover (102) is rotatably connected to the top of the box (101), a frame (103) is fixedly connected inside the box (101), a storage box (104) is snapped into the inside of the frame (103), a display rack (105) is fixedly connected inside the storage box (104), and a protective cover (106) is snapped into the top of the storage box (104).

3. The fusion protein preservation device according to claim 2, characterized in that: The top of the box (101) is provided with a protective groove (107), and the bottom of the top cover (102) is fixedly connected with a protective block (108). The protective block (108) is located inside the protective groove (107), and the side of the protective block (108) away from the top cover (102) is in contact with the inner wall of the protective groove (107).

4. The fusion protein preservation device according to claim 2, characterized in that: The top of the box (101) is provided with a slot (109), and the bottom of the top cover (102) is fixedly connected with a block (110) that works with the slot (109). A soft pad (111) is fixedly connected inside the block (110).

5. The fusion protein preservation device according to claim 2, characterized in that: The storage box (104) has a snap-fit ​​groove (3) on both the left and right sides. The surface of the storage box (104) is provided with a protective sleeve (4). The left and right sides of the inner wall of the protective sleeve (4) are fixedly connected with snap-fit ​​blocks (5) that cooperate with the snap-fit ​​groove (3). The protective sleeve (4) and the snap-fit ​​blocks (5) are both made of aluminum alloy.

6. The fusion protein preservation device according to claim 2, characterized in that: The bottom of the box (101) is provided with a placement groove (6), and an anti-slip pad (7) is inserted into the placement groove (6). The anti-slip pad (7) is made of silicone.

7. The fusion protein preservation device according to claim 2, characterized in that: The top of the top cover (102) has a groove (8), and an adjustment frame (9) is rotatably connected inside the groove (8). An anti-slip plate (10) is fixedly connected to the front side of the adjustment frame (9).

8. The fusion protein preservation device according to claim 2, characterized in that: A fixing rod (11) is fixedly connected to the front side of the box (101), and a limit block (12) is rotatably connected to the surface of the fixing rod (11).

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