Traditional Chinese medicine spray extraction equipment

Abstract

The utility model discloses traditional Chinese medicine spray extraction equipment which comprises an ultrasonic extraction tank, a membrane separation assembly and a vacuum concentrator which are sequentially connected, stirring blades with needle-shaped protrusions and long-strip-shaped holes are arranged in the ultrasonic extraction tank, and a heating jacket is wrapped on the outer wall of the ultrasonic extraction tank; the membrane separation assembly adopts a ceramic microfiltration membrane and a polyether sulfone ultrafiltration membrane which are connected in series; and the vacuum concentrator is provided with a nitrogen protection system and a three-stage gradient condensing device. Through the integrated design of ultrasonic-mechanical synergistic extraction, multi-stage membrane separation and inert atmosphere concentration, efficient extraction, fine purification and low-temperature rapid concentration of effective components of traditional Chinese medicines are realized, the extraction efficiency is higher, the oxidation loss rate of the effective components is lower, the solvent recovery rate is higher, and the cost is lower. The method is suitable for continuous and large-scale production of the heat-sensitive traditional Chinese medicine spray.

Description

TECHNICAL FIELD

[0001] The utility model relates to the field of traditional Chinese medicine preparation processing, concretely relates to a traditional Chinese medicine spray extraction equipment. BACKGROUND

[0002] Traditional Chinese medicine extraction methods such as decoction, soaking and reflux extraction have problems such as low extraction efficiency, long extraction time, easy damage of heat-sensitive components and discontinuous process. At the same time, in the preparation process of traditional Chinese medicine spray, it is difficult to realize efficient connection of extraction, separation and concentration processes, which leads to difficulty in guaranteeing product purity and uniformity. In addition, complicated equipment operation, high energy consumption and inaccurate temperature control also limit the application of traditional equipment. Therefore, there is an urgent need for a traditional Chinese medicine spray extraction equipment with compact structure, continuous process, simple operation and accurate temperature control and efficient extraction to meet the requirements of modern traditional Chinese medicine preparation for product quality and production efficiency. SUMMARY

[0003] The utility model aims at providing a traditional Chinese medicine spray extraction equipment, which realizes rapid and efficient extraction and separation of traditional Chinese medicine active ingredients through the organic combination of ultrasonic assisted extraction, membrane separation technology and vacuum concentration technology, reduces the loss of heat-sensitive components, and ensures product quality and uniformity.

[0004] The utility model discloses a traditional Chinese medicine spray extraction equipment, which comprises an ultrasonic extraction tank, a membrane separation assembly and a vacuum concentrator connected in sequence, a stirring assembly is rotatably arranged in the ultrasonic extraction tank, the stirring assembly comprises a driving motor arranged at the top of the ultrasonic extraction tank, a plurality of groups of stirring blades are arranged on the rotating shaft of the driving motor in a circumferential direction, and the membrane separation assembly comprises a ceramic microfiltration membrane and a polyether sulfone ultrafiltration membrane.

[0005] Preferably, a plurality of needle-shaped protrusions are arranged on the stirring blades, the needle-shaped protrusions are grouped, and a long hole is arranged between each group.

[0006] Preferably, the outer wall of the ultrasonic extraction tank is wrapped with a heating jacket.

[0007] Preferably, the vacuum concentrator comprises an evaporation chamber, the feed inlet at the top of the evaporation chamber is connected with the outlet of the membrane separation assembly, is provided with a flow control valve, and the bottom of the evaporation chamber is provided with a concentrated liquid outlet.

[0008] Preferably, the evaporation chamber is provided with a steam outlet, the steam outlet is connected with a condenser through a one-way valve, the condenser adopts a three-stage series connection of stainless steel corrugated pipes, the inlet temperature of cooling water is gradually reduced, and a collection tank is connected below the condenser.

[0009] Preferably, the evaporation chamber top is provided with an annular pipeline, and nitrogen gas nozzles are arranged on the inner circumferential surface of the annular pipeline; and a mass flow meter is arranged at the gas inlet of the annular pipeline.

[0010] Preferably, the membrane pore sizes of the ceramic microfiltration membrane and the polyethersulfone ultrafiltration membrane are 0.1-1 μm and 5-10 kDa respectively.

[0011] Preferably, the ultrasonic frequency of the ultrasonic extraction tank is 20-40 kHz, and the power density is 50-100 W / L.

[0012] Compared with the prior art, the present application has the following advantages and effects:

[0013] The present application adopts ultrasonic auxiliary extraction technology and a unique stirring blade structure design (needle-shaped protrusions and long holes are arranged on the blade), which significantly enhances the rupture of the cell wall of the traditional Chinese medicinal material and the release of the effective components, shortens the extraction time and improves the extraction efficiency; meanwhile, the ultrasonic extraction tank is wrapped with a heating jacket to ensure uniform temperature control, which further optimizes the extraction effect. The membrane separation assembly utilizes the cascade filtration of the ceramic microfiltration membrane and the polyethersulfone ultrafiltration membrane, effectively removes suspended particles and small impurities, and improves the purity of the extraction liquid, providing high-quality raw materials for subsequent concentration. The vacuum concentrator adopts an evaporation chamber provided with a flow control valve, a multi-stage series-connected stainless steel corrugated pipe condensing system and a U-shaped liquid seal pipe, which not only realizes efficient recovery and concentration of the solvent, but also forms a stable and uniform inert atmosphere through the configuration of the nitrogen gas nozzles in the top annular pipeline and the mass flow meter, effectively inhibits the oxidation reaction and maintains the activity of the effective components of traditional Chinese medicine. Overall, the present application has a compact equipment structure, continuous process and simple operation, can realize automatic control, significantly improves the production efficiency and product quality of traditional Chinese medicine sprays, reduces energy consumption, and has significant technical promotion and application value. BRIEF DESCRIPTION OF DRAWINGS

[0014] Figure 1 is a structural schematic view of a traditional Chinese medicine spray extraction equipment according to an embodiment of the present application.

[0015] Figure 2 is a structural schematic view of a stirring blade according to an embodiment of the present application.

[0016] Figure 3 is a structural schematic view of a membrane separation assembly according to an embodiment of the present application.

[0017] Figure 4 is a working schematic view of nitrogen filling according to an embodiment of the present application.

[0018] Figure 5 is a structural schematic view of an embodiment of the present application.

[0019] Figure No. Ultrasonic extraction tank 11, membrane separation assembly 12, vacuum concentrator 13, stirring assembly 14, drive motor 15, stirring blade 16, ceramic microfiltration membrane 17, polyether sulfone ultrafiltration membrane 18, needle-shaped protrusion 21, long hole 22, heating jacket 23, evaporation chamber 24, membrane separation assembly 25, flow control valve 26, concentrated liquid outlet 27, vapor outlet 31, one-way valve 32, condenser 33, stainless steel bellows 34, collection tank 35, annular pipe 36, nozzle 37, mass flow meter 38. DETAILED DESCRIPTION

[0020] The utility model will be further explained in detail below by combining with the drawings and through examples, the following examples are the explanation of the utility model and the utility model is not limited to the following examples.

[0021] Example:

[0022] Reference Figure 1 - Figure 5 In this embodiment, a traditional Chinese medicine spray extraction equipment is related, which is specifically used for the extraction, separation and concentration of effective components of traditional Chinese medicine, and specifically comprises: ultrasonic extraction tank 11, membrane separation assembly 12 and vacuum concentrator 13 connected in sequence, the ultrasonic extraction tank 11 is rotationally provided with a stirring assembly 14, the stirring assembly 14 includes a drive motor 15 arranged at the top of the ultrasonic extraction tank 11, a plurality of groups of stirring blades 16 are circumferentially arranged on the rotating shaft of the drive motor 15, and the membrane separation assembly 12 includes a ceramic microfiltration membrane 17 and a polyether sulfone ultrafiltration membrane 18.

[0023] Specifically, in this embodiment, the ultrasonic extraction tank 11 is used for extracting traditional Chinese medicinal materials, and the main components include ultrasonic extraction tank 11, membrane separation assembly 12 and vacuum concentrator 13 connected in sequence. The ultrasonic extraction tank 11 is made of high-temperature-resistant and corrosion-resistant materials, and a rotating stirring assembly 14 is arranged inside to ensure that the traditional Chinese medicinal materials and the extraction solvent are fully mixed. The stirring assembly 14 includes a drive motor 15 installed at the top of the extraction tank, and the motor drives a plurality of groups of uniformly arranged stirring blades 16 to rotate circumferentially through the rotating shaft, so that strong fluid disturbance is formed during the extraction process to stir, and at the same time, with the aid of ultrasonic waves, efficient extraction can be realized in a short time, and the extraction efficiency and uniformity are significantly improved.

[0024] During the extraction process, the ultrasonic waves with a frequency of 20-40 kHz and a power density of 50-100 W / L act on the extraction liquid, so that the ultrasonic energy is uniformly transmitted to the stirring system, further improving the contact efficiency between the material and the solvent. After the extraction is completed, the mixed solution containing the effective components of traditional Chinese medicine is transported to the membrane separation assembly 12 through the pipeline. The membrane separation assembly 12 includes a ceramic microfiltration membrane 17 and a polyether sulfone ultrafiltration membrane 18. The membrane pore size of the former is set in the range of 0.1-1 μm, which is used to intercept larger particles and suspended impurities. The latter adopts a molecular weight cutoff standard of 5-10 kDa to further remove small impurities, thereby finely filtering and preliminarily purifying the extraction liquid. This grading filtration method effectively improves the purity of the extraction liquid, providing high-quality raw material liquid for the subsequent vacuum concentration step.

[0025] Referring to Figure 2 The stirring blades 16 are uniformly provided with a plurality of needle-shaped protrusions 21, and the needle-shaped protrusions 21 are arranged in groups at equal intervals, and a long hole 22 is formed between each group of needle-shaped protrusions 21. In this embodiment, by the arrangement of the needle-shaped protrusions 21, a small local shear force can be formed during stirring, promoting the rupture of the cell wall of the traditional Chinese medicinal material, so that the effective components in the cells are more easily released. The long hole 22 helps the liquid to flow smoothly between the stirring blades 16, while reducing the resistance of the stirring blades 16 during stirring.

[0026] In this embodiment, the outer wall of the ultrasonic extraction tank 11 is wrapped with a heating jacket 23, and the extraction tank is uniformly heated by an external heat source (circulating hot water injection) to maintain the stability of the temperature during extraction, and the stirring of the stirring assembly 14 is further improved to improve the dissolution efficiency of the effective components in the medicinal material.

[0027] In this embodiment, the vacuum concentrator 13 includes an evaporation chamber 24, and the feed inlet at the top of the evaporation chamber 24 is connected to the outlet of the membrane separation assembly 12, equipped with a flow control valve 26, which can adjust the flow rate of the extraction liquid entering the evaporation chamber 24 in real time, ensuring that the material continuously and stably enters the evaporation chamber 24, so that the evaporation process is smooth and the concentration effect is uniform. The bottom of the evaporation chamber 24 is provided with a concentrated liquid outlet 27 for discharging the liquid after evaporation and concentration, providing high-concentration traditional Chinese medicine extraction liquid for subsequent spray preparation or product packaging, improving production efficiency and process automation level.

[0028] Referring to Figure 5The evaporation chamber 24 is provided with a vapor outlet 31, the vapor outlet 31 is connected with a condenser 33 through a one-way valve 32, the one-way valve 32 can effectively prevent the backflow of condensate or external medium. The condenser 33 adopts a three-stage series connection of stainless steel bellows 34, the inlet temperature of cooling water is gradually reduced (for example, the inlet temperature of cooling water of the first stage is 15℃, the inlet temperature of cooling water of the second stage is 10℃, and the inlet temperature of cooling water of the third stage is 5℃), so that the solvent vapor is gradually condensed, the efficiency is effectively improved compared with single-stage condensation, and the condenser 33 is connected with a collection tank 35 below, which is used for collecting the cooled solvent for recycling.

[0029] In the embodiment, in order to prevent the extract from reducing the active ingredients due to oxidation during the concentration process, the evaporation chamber 24 is provided with an annular pipeline 36 at the top, and the annular pipeline 36 is circumferentially provided with nitrogen gas nozzles 37. Nitrogen gas is uniformly sprayed into the evaporation chamber 24 through the nozzles 37 to form an inert atmosphere, which effectively prevents the occurrence of oxidation reaction. In addition, a mass flow meter 38 is arranged at the gas inlet of the annular pipeline 36, which is used for real-time monitoring and adjusting the flow of nitrogen gas, so as to ensure the stability of the atmosphere during the concentration process and further ensure the integrity of the effective components of traditional Chinese medicine and the product quality.

[0030] The above described in the specification of the present application is only an example of the present application. Those skilled in the art of the present application can make various modifications or supplements to the described specific embodiments or use similar ways to replace, as long as it does not deviate from the content of the specification of the present application or exceed the scope defined by the claims, which shall belong to the protection scope of the present application.

Claims

1. A traditional Chinese medicine spray extraction device, comprising an ultrasonic extraction tank, a membrane separation assembly and a vacuum concentrator connected in sequence, characterized in that, The ultrasonic extraction tank is provided with a stirring assembly rotating in the tank, the stirring assembly comprises a driving motor arranged on the top of the ultrasonic extraction tank, and a plurality of groups of stirring blades are arranged on the rotating shaft of the driving motor in a circumferential direction.

2. The traditional Chinese medicine spray extraction device according to claim 1, characterized in that: The stirring blades are arranged with a plurality of needle-shaped protrusions, the needle-shaped protrusions are arranged in groups, and a long hole is arranged between each group.

3. The traditional Chinese medicine spray extraction device according to claim 1, characterized in that: The outer wall of the ultrasonic extraction tank is wrapped with a heating jacket.

4. The traditional Chinese medicine spray extraction device according to claim 1, characterized in that: The vacuum concentrator comprises an evaporation chamber, the feed inlet at the top of the evaporation chamber is connected with the outlet of the membrane separation assembly, and a flow control valve is arranged, and the bottom of the evaporation chamber is provided with a concentrated liquid outlet.

5. The traditional Chinese medicine spray extraction device according to claim 4, characterized in that: The evaporation chamber is provided with a steam outlet, the steam outlet is connected with a condenser through a one-way valve, the condenser adopts a three-stage series connection of stainless steel corrugated pipes, the inlet temperature of cooling water is gradually reduced, and a collection tank is connected below the condenser.

6. The traditional Chinese medicine spray extraction device according to claim 4, characterized in that: The top of the evaporation chamber is provided with an annular pipeline, the annular pipeline is circumferentially provided with a nitrogen gas nozzle, and a mass flow meter is arranged at the gas inlet of the annular pipeline.

7. The traditional Chinese medicine spray extraction device according to claim 1, characterized in that: The membrane pore diameters of the ceramic microfiltration membrane and the polyether sulfone ultrafiltration membrane are 0.1-1 μm and 5-10 kDa respectively.

8. The traditional Chinese medicine spray extraction device according to claim 1, characterized in that: The ultrasonic frequency of the ultrasonic extraction tank is 20-40 kHz, and the power density is 50-100 W / L.

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