Mouse irradiation fixator and fixing device
By combining the frame with flexible fixation components, the problems of inconsistent anesthesia time and mismatched fixation in mouse irradiation experiments were solved, achieving efficient mouse fixation without anesthesia and improving experimental efficiency and the reliability of results.
Patent Information
- Application Number
- CN202423064452.4
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-12-12
- Publication Date
- 2026-02-10
- Estimated Expiration
- 2034-12-12
AI Technical Summary
In existing mouse irradiation experiments, individual differences lead to inconsistent anesthesia times, reducing experimental efficiency. Furthermore, the mismatch between the mouse fixation tube and the mouse's body size affects the reliability of the experimental results.
The design employs a combination of a frame and flexible fasteners. The frame secures the mouse with positioning devices, while the flexible fasteners restrict the mouse's movement. Combined with a removable rear panel and lead plate, the irradiation area and region can be adjusted.
It enables mouse fixation without anesthesia, improving experimental efficiency and quality, ensuring experimental consistency and flexibility, and is applicable to the fixation of mice of various sizes.
Smart Images

Figure CN223887009U_ABST
Abstract
Description
Technical Field
[0001] This utility model relates to the field of animal experimental auxiliary equipment technology, and in particular to a mouse irradiation fixator and fixation device. Background Technology
[0002] In the research of radiation medicine and radiation protection, mouse irradiation experiments are frequently required. Generally, for mice receiving the same irradiation dose, researchers anesthetize them and place them in the target area of the irradiator. However, due to individual differences among mice, the anesthesia time varies, significantly reducing experimental efficiency. Existing technology discloses a mouse experimental device, including an operating platform and a mouse fixation tube. The mouse fixation tube is fixed to the operating platform by a fixation device. This existing technology can fix mice in experiments such as tail vein injection and blood collection. However, because the size of experimental mice varies, the internal space of the mouse fixation tube may not perfectly match the mouse's body size. Smaller mice can move freely within the mouse fixation tube, affecting the reliability of the irradiation experiment results. Therefore, to address the above problems and technical needs, a new structure needs to be developed that can improve experimental efficiency while effectively fixing the mice. Summary of the Invention
[0003] The purpose of this invention is to provide a mouse irradiation fixation device and fixation apparatus, which has a simple structure and strong practicality. It can fix the mouse without anesthetizing it during irradiation experiments, thereby improving experimental efficiency and ensuring experimental quality.
[0004] To achieve the above objectives, the technical solution adopted by this utility model is as follows:
[0005] A mouse irradiation fixation device includes a base; a frame is provided on the base; a first through hole is provided on each side of the frame on the base; a positioning element is provided between the two first through holes on the lower surface of the base; and an opening is provided on the side wall of the frame.
[0006] In this invention, the enclosure is used to place the mouse and restrict its range of movement. In practical applications, flexible fasteners such as rubber bands can be used, which are inserted into the opening of the enclosure, with both ends passing through the first through holes on both sides, and then fixed to the positioning component. This works in conjunction with the enclosure to prevent the mouse from moving freely within the enclosure, thus securing the mouse.
[0007] Preferably, the enclosure includes a front baffle, a rear baffle, and two side baffles facing each other; the front baffle, rear baffle, and two side baffles together form the enclosure; the front baffle and side baffles are fixedly mounted on the base; the rear baffle is detachably mounted on the base. The detachable rear baffle facilitates the placement of mice.
[0008] Preferably, the rear baffle has a second through hole; the side baffle has an opening. More preferably, the diameter of the second through hole is 0.3~1.2cm; the width of the opening is 0.2~1.5cm. Even more preferably, the diameter of the second through hole is 0.5~0.8cm; the width of the opening is 0.2~1cm. In practical applications, the mouse's tail can be passed through the second through hole to further restrict its movement; the opening allows a flexible fixing member to bypass the mouse, preventing the mouse from moving freely within the enclosure and thus securing the mouse.
[0009] Preferably, the inner wall of the side baffle is provided with a longitudinal sliding groove; the rear baffle is located within the longitudinal sliding groove. The longitudinal sliding groove is used to fix the rear baffle, so that the rear baffle can be detachably installed on the base.
[0010] Preferably, the mouse irradiation restraint also includes a lead plate; the inner wall of the side baffle is provided with a transverse groove; the upper surface of the front baffle and / or the upper surface of the rear baffle is lower than the position height of the transverse groove; the lead plate is located within the transverse groove. The lead plate is used to shield the irradiation rays. According to the actual irradiation requirements, the lead plate is inserted into the transverse groove to adjust the irradiated part and area of the mouse. The size and specifications of the lead plate are not limited and can be designed as needed. The upper surface of the front baffle and / or the upper surface of the rear baffle is lower than the position height of the transverse groove to facilitate the insertion of the lead plate, while leaving a certain gap between the lead plate and the front baffle and / or the rear baffle to prevent the mouse from suffocating during irradiation.
[0011] Preferably, the diameter of the first through hole is 0.5~1.5cm; the positioning element is a hook. More preferably, the diameter of the first through hole is 0.8~1.2cm. The first through hole allows the flexible fixing element to pass through, so that the flexible fixing element can be fixed on the positioning element to achieve the fixation of the mouse; the shape and size of the hook are selected according to actual needs, as long as it can fix the flexible fixing element, without affecting the realization of the technical effect of this utility model.
[0012] Preferably, the number of frames is multiple. More preferably, the number of first through holes between every two adjacent frames is one. This invention can irradiate multiple mice simultaneously, improving experimental efficiency.
[0013] This utility model also discloses a mouse irradiation fixation device, including the aforementioned mouse irradiation fixator and a flexible fixation component. Preferably, the flexible fixation component is a rubber band. In practical applications, the flexible fixation component can also be other conventional flexible fixation components, such as elastic ropes, as long as they can hold the mouse in place; the flexible fixation component spans the frame, is secured in its opening, and its two ends pass through the first through holes on both sides of the frame, and are fixed to the positioning component.
[0014] Due to the application of the above technical solution, the beneficial effects of this utility model compared with the prior art are as follows: First, the irradiation experiment does not require anesthesia of mice. Through the cooperation of the frame and the flexible fixation component, the mice cannot move freely within the frame, thus improving the efficiency and quality of the experiment. Second, by setting the longitudinal sliding groove, the rear baffle can be detachably installed on the base, which facilitates the placement of the mice. By setting the transverse sliding groove for the insertion of the lead plate, the irradiated part and area of the mouse can be adjusted, which is highly flexible. Third, this utility model is simple to operate, highly practical, and suitable for fixing mice of various sizes. It can conduct irradiation experiments on multiple mice at the same time, ensuring the consistency of the experiment and improving the efficiency of the experiment. Attached Figure Description
[0015] Figure 1 This is a three-dimensional structural diagram of the mouse irradiation fixation device in Example 1.
[0016] Figure 2 This is a side view of the mouse irradiation fixation device of Example 1.
[0017] Figure 3 This is a schematic diagram of the lead plate structure.
[0018] Figure 4 This is a structural schematic diagram of the flexible fastener in Embodiment 4.
[0019] The components include: base 1, lead plate 2, frame 3, first through hole 4, positioning component 5, front baffle 301, rear baffle 302, side baffle 303, second through hole 3021, opening 3031, longitudinal slide groove 3032, and transverse slide groove 3033. Detailed Implementation
[0020] The present invention will be further described below with reference to the accompanying drawings and preferred embodiments. The specific components involved are prior art, and the connection and usage methods between the specific components are conventional techniques.
[0021] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention pertains; the terminology used herein is for the purpose of describing particular embodiments only and is not intended to limit the invention. For example, terms such as “length,” “width,” “upper,” “lower,” “vertical,” “horizontal,” “top,” “bottom,” “inner,” and “outer” indicate orientations or positions based on the orientations or positions shown in the accompanying drawings and are merely for ease of description and should not be construed as limiting the invention. Example 1
[0022] like Figures 1 to 3 As shown:
[0023] A mouse irradiation fixation device includes a base 1 and a lead plate 2; the base is provided with three frames 3; the frames are provided with first through holes 4 on both sides; and a positioning element 5 is provided between two first through holes on the lower surface of the base.
[0024] In this embodiment, there is one first through hole between every two adjacent frames.
[0025] In this embodiment, the diameter of the first through hole is 1 cm.
[0026] In this embodiment, the positioning element is a hook. In practical applications, the shape and size of the hook can be selected according to actual needs, as long as it can fix the flexible fixing element, without affecting the realization of the technical effect of this utility model.
[0027] In this embodiment, the enclosure includes a front baffle 301, a rear baffle 302 and two side baffles 303 that are opposite to each other; the front baffle, the rear baffle and the two side baffles together form the enclosure; the front baffle and the side baffles are fixedly mounted on the base; the rear baffle is detachably mounted on the base.
[0028] In this embodiment, the rear baffle is provided with a second through hole 3021 with a diameter of 0.6cm; the side baffle is provided with an opening 3031 with a width of 0.3cm.
[0029] In this embodiment, the inner wall of the side baffle is provided with a longitudinal groove 3032; the rear baffle is located in the longitudinal groove.
[0030] In this embodiment, the inner wall of the side baffle is provided with a transverse sliding groove 3033; the upper surface of the front baffle and the upper surface of the rear baffle are both lower than the position height of the transverse sliding groove; the lead plate is located in the transverse sliding groove. Example 2
[0031] Based on Embodiment 1, the difference in this embodiment is that the second through hole is omitted, while the rest are the same. Example 3
[0032] Based on Example 1, the difference in this example is that the lead plate and the transverse groove are omitted, while the rest are the same. Example 4
[0033] A mouse irradiation fixation device includes the mouse irradiation fixator of Embodiment 1 and a flexible fixation component. The flexible fixation component is a rubber band, and the structure of the flexible fixation component is described below. Figure 4 .
[0034] The specific method of using the mouse irradiation fixation device of this invention is as follows:
[0035] (1) Remove the back panel, place the mouse inside the enclosure, reset the back panel, and then pass the mouse's tail through the second through hole;
[0036] (2) Take a rubber band and insert it into the opening to hold the mouse in place. Pass both ends through the first through hole on both sides of the frame and fix them on the hook to complete the fixation of the mouse.
[0037] Furthermore, when local irradiation of mice is required, a suitable lead plate is inserted into the transverse groove.
[0038] The above description is only a preferred embodiment of the present utility model. It should be noted that for those skilled in the art, several modifications and improvements can be made without departing from the principle of the present utility model, and these should also be considered to fall within the protection scope of the present utility model.
Claims
1. A mouse irradiation fixator, characterized in that: It includes a base; a frame is provided on the base; a first through hole is provided on each side of the frame on the base; a positioning element is provided between the two first through holes on the lower surface of the base; and an opening is provided on the side wall of the frame.
2. The mouse irradiation fixator according to claim 1, characterized in that: The enclosure includes a front baffle, a rear baffle, and two side baffles that are opposite each other; the front baffle, the rear baffle, and the two side baffles together form the enclosure; the front baffle and the side baffles are fixedly mounted on the base; the rear baffle is detachably mounted on the base.
3. The mouse irradiation fixator according to claim 2, characterized in that: The rear baffle is provided with a second through hole; the side baffle is provided with an opening.
4. The mouse irradiation fixator according to claim 3, characterized in that: The diameter of the second through hole is 0.3~1.2cm; the width of the opening is 0.2~1.5cm.
5. The mouse irradiation fixator according to claim 2, characterized in that: The inner wall of the side baffle is provided with a longitudinal groove; the rear baffle is located within the longitudinal groove.
6. The mouse irradiation fixator according to claim 2, characterized in that: The mouse irradiation fixation device also includes a lead plate; the inner wall of the side baffle is provided with a transverse sliding groove; the upper surface of the front baffle and / or the upper surface of the rear baffle is lower than the position height of the transverse sliding groove; the lead plate is located in the transverse sliding groove.
7. The mouse irradiation fixator according to claim 1, characterized in that: The diameter of the first through hole is 0.5~1.5cm; the positioning element is a hook.
8. The mouse irradiation fixator according to claim 1, characterized in that: The number of the enclosures is multiple.
9. The mouse irradiation fixator according to claim 8, characterized in that: The number of first through holes between each pair of adjacent frames is 1.
10. A mouse irradiation fixation device, characterized in that: Includes the mouse irradiation fixator and flexible fixation element as described in claim 1.