Heparin calcium preparation reaction equipment

By designing an automated heparin calcium preparation reaction device, the problem of increased labor intensity due to manual transfer and sieving was solved, and automated filtration, sieving, and stirring were achieved, improving work efficiency and reducing costs.

CN223915397UActive Publication Date: 2026-02-17HUBEI YINUORUI BIOLOGICAL PHARMA
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Patent Information

Application Number
CN202520327681.6
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2025-02-27
Publication Date
2026-02-17
Estimated Expiration
2035-02-27

AI Technical Summary

Technical Problem

The preparation of heparin calcium requires manual transfer of incompletely dissolved raw materials or impurities for filtration and sieving, which increases the workload and cost for workers.

Method used

A reaction apparatus for preparing heparin calcium was designed, comprising a reaction vessel, a sieve box, and a stirring system. The apparatus utilizes a motor-driven lead screw to move the sieve plate for automatic filtration and sieving, and a motor-driven rotating rod to drive the stirring rod for automatic stirring, reducing manual operation.

Benefits of technology

It has automated the filtration, screening, and mixing processes, improving work efficiency and reducing the labor intensity and costs for staff.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model discloses heparin calcium preparation reaction equipment, which belongs to the technical field of heparin calcium preparation, and comprises a base, a reaction kettle is fixedly arranged on the base, a connecting pipe is fixedly arranged on the reaction kettle, the connecting pipe is arranged at the position of the reaction kettle close to the base, one end of the connecting pipe is fixedly provided with a screen box, and the other end of the connecting pipe is fixedly provided with a filter screen. A sliding groove is formed in the screen box, a sliding rod is fixedly installed in the sliding groove, a lead screw is installed in the sliding groove through a bearing, and a second motor is installed at the end, penetrating through the screen box, of the lead screw. According to the heparin calcium preparation reaction equipment, raw materials in the screen box are filtered and screened, in the filtering and screening work, the incompletely dissolved raw materials or impurities can remain on the screen plate, the dissolved raw materials can pass through the screen holes and then are discharged through the discharging pipe, and when excessive undissolved raw materials or impurities remain on the screen plate, the raw materials can be discharged through the discharging pipe. A worker can clean the sieve plate by opening the sealing door and does not need to manually transfer raw materials, so that the working efficiency is improved.
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Description

Technical Field

[0001] This invention belongs to the field of heparin calcium preparation technology, specifically a heparin calcium preparation reaction device. Background Technology

[0002] Heparin calcium is a calcium salt form of heparin. Heparin is a widely used anticoagulant drug. Heparin calcium is similar to heparin sodium in that it has anticoagulant effects. However, heparin calcium has a lower risk of local pain and bleeding during injection. In summary, heparin calcium is an anticoagulant drug mainly used to prevent and treat thrombotic diseases, and it is less painful when injected subcutaneously.

[0003] Currently, the preparation of heparin calcium requires the raw materials to be placed in a special reaction vessel for processing. After the reaction in the reaction vessel, the raw materials often need to be manually transferred to special equipment to filter and screen any incompletely dissolved raw materials or impurities. This process greatly increases the workload of the staff, and raw materials may also fall during the transfer process, thus increasing the operating costs. Utility Model Content

[0004] To overcome the above-mentioned defects, this utility model provides a heparin calcium preparation reaction device, which solves the problem that in the current preparation of heparin calcium, it is necessary to put the raw materials into a special reaction vessel for processing. After the reaction in the reaction vessel, the raw materials often need to be manually transferred to a special device to filter and screen the incompletely dissolved raw materials or impurities. This process greatly increases the workload of the workers, and the raw materials may also fall during the transfer process, thereby increasing the working cost.

[0005] To achieve the above objectives, this utility model provides the following technical solution: a heparin calcium preparation reaction device, comprising a base, a reaction vessel fixedly mounted on the base, a connecting pipe fixedly mounted on the reaction vessel, the connecting pipe being installed near the base of the reaction vessel, a sieve box fixedly mounted at one end of the connecting pipe, a sliding groove being provided inside the sieve box, a sliding rod being fixedly mounted inside the sliding groove, a lead screw being mounted inside the sliding groove via a bearing, a second motor being mounted at one end of the lead screw passing through the sieve box, a protective box being provided outside the second motor, the protective box being mounted on the sieve box, a sieve plate being mounted on the sliding rod and the lead screw, the sieve plate being installed in the sliding groove, a plurality of sieve holes being provided on the sieve plate, and a sealing door being fixedly mounted on the sieve box.

[0006] As a further embodiment of this utility model: a discharge pipe is connected to the screen box, and the discharge pipe is connected below the sealing door.

[0007] As a further embodiment of this utility model: the reaction vessel is provided with a feeding port, and a sealing plug is slidably installed inside the feeding port.

[0008] As a further embodiment of this utility model: a motor is installed on the reactor, and a rotating rod is connected to the output shaft of the motor.

[0009] As a further embodiment of this utility model: a plurality of stirring rods are fixedly installed on the rotating rod, and a sealing plate is provided on the reaction vessel.

[0010] As a further embodiment of this utility model: an electric valve is fixedly installed on the connecting pipe, and two door handles are fixedly installed on the sealing door.

[0011] Compared with the prior art, the beneficial effects of this utility model are as follows:

[0012] 1. This heparin calcium preparation reaction equipment, through the setting of a lead screw, a second motor, a sliding rod, and a sieve plate, allows the operator to operate the equipment. During operation, the operator opens the second motor installed inside the protective box. Since the output shaft of the second motor is connected to the lead screw, the operation of the second motor drives the lead screw to rotate. Because the sieve box has a sliding groove in which the sieve plate is slidably installed, the rotation of the lead screw causes the sieve plate to move within the sliding rod and the sliding groove, thereby filtering and screening the raw materials entering the sieve box. During the filtering and screening process, incompletely dissolved raw materials or impurities remain on the sieve plate, while dissolved raw materials pass through the sieve holes and are discharged through the discharge pipe. When too much undissolved raw material or impurities remain on the sieve plate, the operator can simply open the sealed door to clean the sieve plate, eliminating the need for manual material transfer and improving work efficiency.

[0013] 2. This heparin calcium preparation reaction equipment, through the setting of a sealing plug, motor one, feeding port, and stirring rods, allows the operator to remove the sealing plug during operation, pour the raw materials to be reacted into the reaction vessel through the feeding port, and then turn on motor one installed on the reaction vessel. The output shaft of motor one drives the rotating rod to rotate, and the rotation of the rotating rod drives several stirring rods installed on it to rotate synchronously, thereby fully stirring and mixing the raw materials in the reaction vessel without the need for manual stirring, saving time and labor. Attached Figure Description

[0014] Figure 1 This is a three-dimensional structural diagram of the present invention;

[0015] Figure 2 This is a schematic diagram of the structure of the base and connecting tube of this utility model;

[0016] Figure 3 This is a schematic diagram of the connection between the sieve box and the sieve plate of this utility model;

[0017] Figure 4 This is a schematic diagram of the structure of the motor and the slide bar of this utility model;

[0018] In the diagram: 1. Base; 2. Reactor; 3. Inlet; 4. Sealing plug; 5. Motor 1; 6. Sealing plate; 7. Connecting pipe; 8. Electric valve; 9. Screen box; 10. Sealing door; 11. Door handle; 12. Discharge pipe; 13. Rotating rod; 14. Stirring rod; 15. Slide groove; 16. Screen plate; 17. Screen hole; 18. Protective box; 19. Motor 2; 20. Lead screw; 21. Slide rod. Detailed Implementation

[0019] The technical solution of this patent will be further described in detail below with reference to specific embodiments.

[0020] like Figure 1-4 As shown, this utility model provides a technical solution: a heparin calcium preparation reaction device, including a base 1, a reaction vessel 2 fixedly installed on the base 1, a motor 5 installed on the reaction vessel 2, and a rotating rod 13 connected to the output shaft of the motor 5. Because the motor 5 is installed, the output shaft of the motor 5 can drive the rotating rod 13 and several stirring rods 14 fixedly installed on the rotating rod 13 to rotate, thereby fully reacting and mixing the raw materials in the reaction vessel 2, eliminating the need for manual stirring by the staff and reducing the workload of the staff.

[0021] Several stirring rods 14 are fixedly installed on the rotating rod 13, and a sealing plate 6 is provided on the reactor 2.

[0022] The reactor 2 is equipped with a feeding port 3, and a sealing plug 4 is slidably installed inside the feeding port 3. Because the sealing plug 4 is slidably installed, impurities or dust can be prevented from entering during the stirring process, thus preventing the raw materials from being contaminated and avoiding affecting the quality.

[0023] A connecting pipe 7 is fixedly installed on the reactor 2, and an electric valve 8 is fixedly installed on the connecting pipe 7. Two door handles 11 are fixedly installed on the sealing door 10. Because of the electric valve 8, the discharge rate of the raw materials can be freely controlled, which is convenient for the staff to adjust and collect, and improves the stability of the operation.

[0024] The connecting pipe 7 is installed in the reactor 2 near the base 1. A screen box 9 is fixedly installed at one end of the connecting pipe 7. A discharge pipe 12 is connected to the screen box 9 and is connected to the bottom of the sealing door 10.

[0025] The screen box 9 has a sliding groove 15, and a sliding rod 21 is fixedly installed in the sliding groove 15. A lead screw 20 is installed in the sliding groove 15 through a bearing. A motor 19 is installed at one end of the lead screw 20 that passes through the screen box 9. Because of the motor 19, the output shaft of the motor 19 can drive the lead screw 20 installed in the sliding groove 15 to rotate. The rotation of the lead screw 20 can drive the screen plate 16 installed on it to move in the sliding groove 15, thereby filtering and screening the raw materials entering the screen box 9. There is no need for the staff to manually transfer the raw materials, which improves the work efficiency.

[0026] The motor 2 19 is equipped with a protective box 18, which is installed on the screen box 9. The slide rod 21 and the lead screw 20 are equipped with a screen plate 16, which is installed in the slide groove 15. The screen plate 16 has several screen holes 17. A sealing door 10 is fixedly installed on the screen box 9. Because of the sealing door 10, when it is necessary to clean the screen plate 16, the staff can open the sealing door 10 through the door handle 11, which facilitates the subsequent cleaning of the screen plate 16 and prevents the screen plate 16 from becoming blocked.

[0027] The working principle of this utility model is as follows: When working, the operator opens the motor 2 19 installed in the protective box 18. Since the output shaft of the motor 2 19 is connected to the lead screw 20, the operation of the motor 2 19 will drive the lead screw 20 to rotate. Since the screen box 9 is provided with a sliding groove 15, and the screen plate 16 is slidably installed in the sliding groove 15, the rotation of the lead screw 20 will drive the screen plate 16 installed on it to move in the sliding rod 21 and the sliding groove 15, thereby filtering and screening the raw materials entering the screen box 9. During the filtering and screening process, the undissolved raw materials or impurities will remain on the screen plate 16, and the dissolved raw materials will pass through the screen holes 17 and then be discharged through the discharge pipe 12. When too much undissolved raw material or impurities remain on the screen plate 16, the operator can open the sealing door 10 to clean the screen plate 16.

[0028] During operation, the operator removes the sealing plug 4 and pours the raw materials to be reacted into the reactor 2 through the inlet 3. Then, the operator turns on the motor 5 installed on the reactor 2. The output shaft of the motor 5 drives the rotating rod 13 to rotate. The rotation of the rotating rod 13 drives several stirring rods 14 installed on it to rotate synchronously, thereby fully stirring and mixing the raw materials in the reactor 2.

[0029] In the description of this utility model, it should be noted that, unless otherwise explicitly specified and limited, the terms "installation," "connection," and "joining" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; and they can refer to the internal connection of two components. Those skilled in the art can understand the specific meaning of the above terms in this utility model based on the specific circumstances.

[0030] The preferred embodiments of this patent have been described in detail above. However, this patent is not limited to the above embodiments. Within the scope of knowledge possessed by those skilled in the art, various changes can be made without departing from the spirit of this patent.

Claims

1. A heparin calcium preparation reaction apparatus, comprising a base (1), characterized in that: A reaction vessel (2) is fixedly installed on the base (1). A connecting pipe (7) is fixedly installed on the reaction vessel (2). The connecting pipe (7) is installed on the reaction vessel (2) near the base (1). A sieve box (9) is fixedly installed at one end of the connecting pipe (7). A sliding groove (15) is provided in the sieve box (9). A sliding rod (21) is fixedly installed in the sliding groove (15). A lead screw (20) is installed in the sliding groove (15) through a bearing. A motor (19) is installed at one end of the lead screw (20) that passes through the screen box (9). A protective box (18) is provided outside the motor (19). The protective box (18) is installed on the screen box (9). A screen plate (16) is installed on the slide rod (21) and the lead screw (20). The screen plate (16) is installed in the slide groove (15). Several screen holes (17) are opened on the screen plate (16). A sealing door (10) is fixedly installed on the screen box (9).

2. The heparin calcium preparation reaction apparatus according to claim 1, characterized in that: The screen box (9) is connected to a discharge pipe (12), which is connected below the sealing door (10).

3. The heparin calcium preparation reaction apparatus according to claim 1, characterized in that: The reactor (2) is provided with a filling port (3), and a sealing plug (4) is slidably installed inside the filling port (3).

4. The heparin calcium preparation reaction apparatus according to claim 1, characterized in that: The reactor (2) is equipped with a motor (5), and a rotating rod (13) is connected to the output shaft of the motor (5).

5. The heparin calcium preparation reaction apparatus according to claim 4, characterized in that: Several stirring rods (14) are fixedly installed on the rotating rod (13), and a sealing plate (6) is provided on the reactor (2).

6. The heparin calcium preparation reaction apparatus according to claim 1, characterized in that: An electric valve (8) is fixedly installed on the connecting pipe (7), and two door handles (11) are fixedly installed on the sealing door (10).