Multi-channel closed type inorganic paper chromatographic analysis experimental device

Abstract

A multichannel closed chromatographic analysis experimental device on inorganic paper relates to a chromatographic analysis experimental device, a device main body comprises four groups of independent separation units, a sealing cover and a double-layer protection rubber plug are arranged at the top, and a manual pipette and an electric diversion system are connected at the bottom. Chromatographic paper is folded into a hexagonal column to be placed in the unit, and synchronous treatment of four samples is achieved in cooperation with a sealing structure. A long suction tube rubber head pressing type waste liquid recovery or electric circulating pump flow guide treatment is adopted to form a closed waste liquid collection system. Through actual measurement, the device reduces the volatilization amount of ammonia water by 87%, and the time consumption of a single experiment is reduced to 1 / 3 of that of a traditional method. The method can be widely applied to paper chromatography analysis experiments in the fields of chemistry, biology and the like, and is particularly suitable for teaching and scientific research scenes requiring batch sample processing.

Description

Technical Field

[0001] This utility model relates to a chromatographic analysis experimental device, and in particular to a multi-channel closed inorganic paper chromatographic analysis experimental device. Background Technology

[0002] Existing inorganic paper chromatography devices have three major technical drawbacks:

[0003] 1. Research Efficiency Issues: Traditional inorganic paper chromatography apparatuses can only process a single sample per experiment. This limitation significantly hinders the efficient conduct of research when faced with the need for large-scale sample analysis. Taking a teaching experiment on the component analysis of large-scale paper chromatography samples as an example, the sample-by-sample processing mode greatly extends the experimental cycle, severely slowing down the overall research process and making it difficult to meet the needs of large sample volumes.

[0004] 2. Reagent Waste and Safety Hazards: The original apparatus employed an open design, leading to the rapid and significant evaporation of mobile phase solvents (commonly concentrated hydrochloric acid, ammonia, acetone, etc.). On one hand, solvent evaporation directly results in unnecessary reagent waste, increasing experimental costs and causing less noticeable experimental phenomena. On the other hand, the irritating gases produced by evaporation permeate the experimental environment, posing a serious threat to the health of laboratory personnel exposed to this environment for extended periods. Prolonged exposure to such volatile gases significantly increases the risk of respiratory illnesses and other health problems for laboratory personnel.

[0005] 3. Complex Operating Procedures and Risk of Secondary Pollution: After the chromatographic development process, traditional apparatus requires manual opening of the lid to handle residual waste liquid. This process is not only cumbersome and time-consuming, but also, especially for waste liquid containing hazardous substances, improper handling can easily lead to secondary pollution, posing a potential threat to the experimental environment and even the surrounding ecosystem.

[0006] Traditional paper chromatography equipment suffers from problems such as low efficiency, serious pollution, and high operational risks. Summary of the Invention

[0007] The purpose of this invention is to provide a multi-channel closed inorganic paper chromatography analysis experimental device. This device has the ability to process four sets of samples simultaneously, and is equipped with a fully enclosed protection system and manual or automatic waste liquid collection function, thereby improving the safety, environmental protection and work efficiency of paper chromatography analysis.

[0008] The objective of this utility model is achieved through the following technical solution:

[0009] A multi-channel closed inorganic paper-based chromatography analysis experimental device includes a bottle cap and a bottle body. The bottle cap has two silicone holes on its left and right sides. The bottle cap consists of an inner protective layer and an outer protective layer. The inner layer is a transparent glass observation window, and the outer layer is an ABS engineering plastic protective cap with a silicone sealing ring. An integrated activated carbon filter is installed between the inner and outer layers. The bottle body is tightly connected to the bottle body via a screw cap. The bottle body contains four independent chromatographic cell units composed of glass partitions. Each partition has two rows of perforations at its lower edge. Four sets of samples are spread in parallel, ensuring uniform solvent diffusion and a uniform mobile phase solvent distribution. A suction tube is inserted through the silicone hole on the left side of the bottle cap, and a syringe is inserted through the silicone hole on the right side. In electric mode, the suction tube is connected to a guide tube, which in turn connects to an electric pump leading to a waste liquid tank.

[0010] The aforementioned multi-channel closed inorganic paper chromatography analysis experimental device, wherein the bottle experimental unit is separated by glass partitions and equipped with four independent chromatographic cell units composed of glass plates, and four groups of samples are developed in parallel.

[0011] The aforementioned multi-channel closed inorganic paper chromatography analysis experimental device comprises a chromatographic paper folded into a hexagonal column and placed in each partition unit, with the filter paper not in contact with the bottle body or partition; a suction tube is inserted into the silicone hole on the left side of the bottle cap, and a syringe is inserted into the silicone hole on the right side; in manual mode, the suction tube is connected to a guide tube, which is connected to an electric pump to the waste liquid tank.

[0012] The multi-channel closed inorganic paper chromatography experimental device has a syringe inlet on the right side of the silica gel hole and a pipette inlet on the left side.

[0013] The multi-channel closed inorganic paper chromatography analysis experimental device is described above, wherein an integrated activated carbon filter element is installed in the bottle cap interlayer.

[0014] The multi-channel closed inorganic paper chromatography analysis experimental device is provided with a silicone sealing ring on the outer layer of the protective cover.

[0015] The advantages and effects of this utility model are:

[0016] 1. This novel multi-channel closed-loop inorganic paper chromatography experimental apparatus offers significant advantages over traditional inorganic paper chromatography devices. In terms of research efficiency, this apparatus overcomes the limitation of traditional devices that can only process a single sample at a time. Its multi-channel design allows for the simultaneous processing of multiple samples in a single experiment. This drastically shortens the experimental cycle and accelerates the research process when facing large-scale sample analysis needs, greatly improving experimental teaching efficiency and effectively meeting the demands of modern chemical experiments for energy conservation, high efficiency, and environmental friendliness.

[0017] 2. Regarding reagent use and safety, this invention employs a closed-loop design, effectively preventing the large-scale evaporation of mobile phase solvents (such as concentrated hydrochloric acid, ammonia, acetone, etc.). On one hand, this reduces unnecessary reagent waste and lowers experimental costs; on the other hand, it eliminates the spread of irritating gases generated by evaporation in the experimental environment, removing threats to the health of experimental personnel and significantly reducing the risk of respiratory diseases and other health problems.

[0018] 3. Regarding the operational process, after the chromatographic development process is completed, there is no need for laboratory personnel to manually open the cap to handle residual waste liquid, simplifying the operation process and saving a significant amount of manpower and time costs. At the same time, it avoids secondary pollution problems that may be caused by improper operation during manual waste liquid handling, effectively protecting the experimental environment and the surrounding ecological environment. Attached Figure Description

[0019] Figure 1 This is a front view showing the layout and sealing structure of the four-unit assembly of this utility model;

[0020] Figure 2 A schematic diagram of the structure of the bottle cap designed for injecting reagents and sealing and collecting waste liquid according to this utility model;

[0021] Figure 3 This is a cross-sectional schematic diagram of the waste liquid recovery system of the straw and syringe connection structure of this utility model;

[0022] Figure 4 This is a top view of the bottle body illustrating the layout design of the chromatography filter paper column for this utility model.

[0023] In the diagram: 1. Silicone pore; 2. Bottle cap; 3. Glass bottle body; 4. Glass partition; 5. Liquid permeation hole of the partition; 6. Long needle syringe; 7. Suction tube; 8. Bottle cap interlayer; 9. Chromatography filter paper column; 10. Inner layer of protective cap; 11. Outer layer of protective cap. Detailed Implementation

[0024] The present invention will now be described in detail with reference to the embodiments shown in the accompanying drawings.

[0025] This device consists of three core modules:

[0026] 1. Four-unit experimental unit

[0027] Two separate glass partitions (100×150×2mm / piece) are used to form four independent chromatographic cell units that are vertically and equidistantly intersected. Each partition (50×150×2mm / piece) has two rows of holes at a height of 10mm from the lower edge, which enables the parallel development of four sets of samples, uniform distribution of mobile phase solvent, and ensures balanced solvent diffusion.

[0028] 2. Closed-loop protection system

[0029] The top is equipped with a double-sealed cover: the inner layer is a 5mm thick transparent glass observation window, and the outer layer is covered with an ABS engineering plastic protective cover with a silicone sealing ring and two silicone holes (Φ5mm). An integrated activated carbon filter is located between the inner and outer layers to effectively adsorb volatile substances such as acid mist and ammonia.

[0030] 3. Waste liquid recovery system

[0031] Automatic recycling: A long glass straw (Φ5×200mm) is directly connected to a central waste liquid bottle (500ml) via a liquid guide tube. Once deployed, the guide tube connects to the straw, and the solenoid valve is activated to automatically recycle the waste liquid through a negative pressure device.

[0032] Manual recycling: After unfolding, squeeze the rubber head at the top of the straw to draw the waste liquid into the straw. After pulling it out from the bottle cap, squeeze the waste liquid into the waste liquid bucket. Example 1

[0033] The multi-channel closed inorganic paper chromatography experimental device includes a cap 2 and a bottle body 3. The cap has two silicone holes 1 on its left and right sides. The cap consists of an inner and an outer layer; the inner layer is a 5mm thick transparent glass observation window, and the outer layer is an ABS engineering plastic protective cap 11 with a silicone sealing ring. It is tightly connected to the bottle body 3 via a screw cap. The bottle body 3 contains four independent chromatographic cell units composed of four glass partitions 4. Each partition has two rows of permeation holes 5 at a height of 10mm from its lower edge, allowing for parallel development of four sets of samples, uniform distribution of the mobile phase solvent, and balanced solvent diffusion. During the experiment, the chromatographic paper is folded into a hexagonal column and placed in each partition unit, ensuring that the filter paper does not contact the bottle body or partitions. A suction tube 7 is inserted into the silicone hole on the left side of the cap, and a syringe 6 is inserted into the silicone hole on the right side. The prepared developing solvent solution is injected into the bottom of the bottle, and the cap is then closed and sealed. The development process is monitored through the glass bottle body 3, and the four sets of samples are separated simultaneously. In manual mode, connect the suction tube 7 to the liquid guide tube and turn on the electric pump to remove the waste liquid into the waste liquid tank. Example 2

[0034] The multi-channel closed inorganic paper chromatography experimental device includes a cap 2 and a bottle body 3. The cap has two silicone holes 1 on its left and right sides. The cap consists of an inner and an outer layer; the inner layer is a 5mm thick transparent glass observation window, and the outer layer is an ABS engineering plastic protective cap 11 with a silicone sealing ring. It is tightly connected to the bottle body 3 via a screw cap. The bottle body 3 contains four independent chromatographic cell units composed of four glass partitions 4. Each partition has two rows of permeable holes 5 at a height of 10mm from its lower edge, allowing for parallel development of four sets of samples, uniform distribution of the mobile phase solvent, and balanced solvent diffusion. During the experiment, the chromatographic paper is folded into a hexagonal column and placed in each partition unit, ensuring that the filter paper does not contact the bottle body or partitions. A suction tube 7 is inserted into the silicone hole on the left side of the cap, and a syringe 6 is inserted into the silicone hole on the right side. The prepared developing solvent solution is injected into the bottom of the bottle, and the cap is then closed and sealed. The development process is monitored through the glass bottle body 3, and the four sets of samples are separated simultaneously. In electric mode, connect the suction tube 7 to the guide tube and turn on the electric pump to remove the waste liquid into the waste liquid container. In manual mode, connect the suction tube 7 to the rubber head, squeeze the rubber head to suck the waste liquid into the suction tube, and then pull it out and transfer it into the waste liquid container.

[0035] During the experiment, the chromatographic paper is folded into a hexagonal column and placed in each separator unit, ensuring that the filter paper does not contact the bottle body or separator. After injecting the mobile phase using a syringe, the sealing cap is closed. The separation process is monitored through the glass bottle, and the four groups of samples are separated simultaneously. If the waste liquid is removed manually after the experiment, the rubber tip on the top of the long pipette is pressed, drawing the waste liquid into the pipette. The pipette is then pulled out, and the waste liquid is squeezed into a waste container for recycling. If the waste liquid is removed electrically, the external end of the pipette is connected to a guide tube, which is then connected to a circulation pump. The pump's suction force collects the residual liquid through the guide tube into a collection bottle for unified treatment. Actual test data shows that ammonia evaporation is reduced by 87%, and the time required for a single experiment is reduced to one-third of that of traditional methods. The bottle cap of this device features a double-layer sealing structure: an inner layer of 5mm thick transparent glass observation window, and an outer layer of ABS engineering plastic protective cap with a silicone sealing ring. The cap and bottle body are tightly connected via a screw thread. An integrated activated carbon filter is integrated between the inner and outer layers to effectively adsorb volatile substances such as acid mist and ammonia. The bottle cap has two silicone holes (Φ5mm) for inserting the pipette and syringe needle, which are used separately. The pipette diameter is 5mm; the pointed end is inserted into the bottom of the bottle through the silicone hole on the left side of the cap, and the other end can be connected to a manual waste removal nozzle or an electrically operated waste removal tube. The syringe uses a capacity appropriate for the experimental requirements, with a 250mm long needle inserted vertically into the bottom of the bottle through the silicone hole on the right side of the cap, ensuring that all the developing solvent solution is injected into the bottom of the bottle. The four independent chromatographic cell units of this device have glass partitions (50×150×2mm / piece) placed vertically in the bottle. The partitions have two rows of holes 10mm above the bottom, allowing for parallel development of four samples, uniform distribution of the mobile phase solvent, and ensuring balanced solvent diffusion.

Claims

1. A multi-channel closed-loop inorganic paper-based chromatographic analysis experimental apparatus, characterized in that, The device includes a bottle cap (2) and a bottle body (3). The bottle cap has two silicone holes (1) on the left and right sides. The bottle cap is divided into an inner protective cap (10) and an outer protective cap (11). The inner layer is a transparent glass observation window, and the outer layer is an ABS engineering plastic protective cap with a silicone sealing ring. An integrated activated carbon filter (8) is provided between the inner and outer layers. The bottle cap is tightly connected to the bottle body (3) through a screw cap. The bottle body (3) is equipped with a glass partition (4) consisting of four glass plates forming an independent chromatographic cell unit. Each partition has two rows of liquid permeation holes (5) at a height above the lower edge. Four sets of samples are spread in parallel, and the solvent diffuses evenly. The mobile phase solvent is evenly distributed. A suction tube (7) is inserted into the silicone hole on the left side of the bottle cap, and a syringe (6) is inserted into the silicone hole on the right side. The suction tube in electric mode is connected to the liquid guide tube and connected to the electric pump to the waste liquid tank.

2. The multi-channel closed-loop inorganic paper-based chromatographic analysis experimental apparatus according to claim 1, characterized in that, The experimental unit of the bottle (3) is separated by glass partitions and equipped with an independent chromatographic cell unit glass partition (4) consisting of four glass plates, and four groups of samples are developed in parallel.

3. The multi-channel closed-loop inorganic paper-based chromatography experimental apparatus according to claim 1, characterized in that, The right side of the silicone hole (1) is the syringe inlet, and the left side is the suction tube inlet.

4. The multi-channel closed-loop inorganic paper-based chromatography experimental apparatus according to claim 1, characterized in that, The outer layer (11) of the protective cover is equipped with a silicone sealing ring.

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