Crystallization kettle for fermentation engineering

Abstract

The utility model discloses a crystallization kettle for fermentation engineering, which relates to the technical field of fermentation engineering and comprises a crystallization kettle body, the surface of the crystallization kettle body is wrapped with a heat insulation cover, the top of the crystallization kettle body is respectively provided with an observation window and a material port, the top of the crystallization kettle body is provided with a motor, and the output end of the motor is provided with a speed reducer. The speed reducer is fixedly installed at the top of the crystallization kettle body, the output end of the speed reducer is fixedly sleeved with a frame type stirrer, supporting legs are fixedly installed on the side face of the heat preservation cover, flow deflectors are arranged in the heat preservation cover, and heating wires are arranged in the heat preservation cover; the hot water cavity and the cold water cavity in the energy recovery device are made of stainless steel and are separated in a heat insulation manner, and the Peltier effect of the semiconductor chilling plate is combined, so that when the crystallization kettle is cooled, discharged high-temperature heat medium heat can be transferred to the heating surface to maintain the high temperature of the hot water cavity, and the refrigeration surface reduces the temperature of the cold water cavity to reserve cold energy; bidirectional energy utilization is achieved, and energy waste is reduced.

Description

TECHNICAL FIELD

[0001] The utility model relates to fermentation engineering technical field especially relates to a crystallization kettle for fermentation engineering. BACKGROUND

[0002] When producing fusidic acid by fermentation method, a crystallization kettle is usually needed in the subsequent separation and purification process. The fermentation broth contains a large amount of impurities and other metabolites, which need to be preliminarily separated by filtration, extraction and other methods to obtain a crude extract containing fusidic acid. The crystallization kettle can further process the crude extract through heating, stirring, cooling and other operations, so that fusidic acid is crystallized and separated from other impurities in a specific solvent system, thereby improving the purity of fusidic acid.

[0003] When fusidic acid is precipitated using a crystallization kettle, repeated heating and cooling are required, which will cause a large amount of energy waste if there is no good energy recovery and utilization measures. Moreover, a certain time is needed for each heating and cooling process to reach the target temperature, which may prolong the entire production cycle and reduce the production efficiency. Therefore, in view of the above phenomenon, a crystallization kettle for fermentation engineering is proposed to recover and utilize energy. SUMMARY

[0004] The utility model provides a crystallization kettle for fermentation engineering, which solves the technical problems in the background art.

[0005] To solve the above technical problems, the utility model provides a crystallization kettle for fermentation engineering, which comprises a crystallization kettle body, the surface of the crystallization kettle body is wrapped with a heat preservation cover, the top of the crystallization kettle body is respectively provided with an observation window and a material port, the top of the crystallization kettle body is provided with a motor, the output end of the motor is provided with a speed reducer, the speed reducer is fixedly installed on the top of the crystallization kettle body, a frame stirrer is fixedly sleeved on the output end of the speed reducer, the side surface of the heat preservation cover is fixedly installed with supporting legs, the inside of the heat preservation cover is provided with a flow guide vane, and the inside of the heat preservation cover is provided with a heating wire.

[0006] In some embodiments, the flow guide vane is spiral-shaped, and the heating wire is located between the flow guide vanes.

[0007] In some embodiments, the bottom of the heat preservation cover is provided with an inlet, the side surface of the heat preservation cover is provided with an outlet, and an energy recovery device and a water pump are connected in series between the inlet and the outlet.

[0008] In some embodiments, the energy recovery device comprises a hot water cavity and a cold water cavity, a semiconductor refrigeration sheet is arranged between the hot water cavity and the cold water cavity, the heating surface of the semiconductor refrigeration sheet is attached to the hot water cavity, and the refrigeration surface of the semiconductor refrigeration sheet is attached to the cold water cavity.

[0009] In some embodiments, the energy recovery device further comprises a first electromagnetic reversing valve and a second electromagnetic reversing valve, the first electromagnetic reversing valve is connected with one end of the liquid outlet, and the second electromagnetic reversing valve is connected with the other end of the liquid inlet.

[0010] In some embodiments, a thermometer is connected in series on the connecting pipeline of the energy recovery device and the liquid outlet.

[0011] Compared with the related art, the crystallization kettle for fermentation engineering has the following beneficial effects:

[0012] The crystallization kettle for fermentation engineering is characterized in that the spiral flow guide piece in the heat preservation cover is made of a metal sheet and closely adheres to the inner wall, and the heating wire is made of a high-resistance and high-temperature-resistant material such as nickel-chromium alloy and is arranged between the flow guide pieces.

[0013] The crystallization kettle for fermentation engineering is characterized in that the hot water cavity and the cold water cavity in the energy recovery device are made of stainless steel and are heat-insulated and separated, and the Peltier effect of the semiconductor refrigeration piece is combined to transfer the heat of the discharged high-temperature heat medium to the heating surface to maintain the high temperature of the hot water cavity and reduce the temperature of the cold water cavity to reserve cold energy when the crystallization kettle is cooled, thereby realizing bidirectional energy utilization and reducing energy waste.

[0014] The crystallization kettle for fermentation engineering is characterized in that the high-precision thermometer on the connecting pipeline of the energy recovery device and the liquid outlet monitors the temperature of the heat medium in real time, feeds back to the control system, and automatically controls the working state of the first electromagnetic reversing valve, the second electromagnetic reversing valve and the semiconductor refrigeration piece according to the preset threshold value. BRIEF DESCRIPTION OF DRAWINGS

[0015] Figure 1 It is a whole structure schematic view of the utility model;

[0016] Figure 2 It is a water circulation schematic view of the utility model.

[0017] Reference numerals in the drawing: 1, crystallization kettle body; 2, heat preservation cover; 3, observation window; 4, material port; 5, speed reducer; 6, motor; 7, frame stirrer; 8, supporting leg; 21, flow guide piece; 22, heating wire; 23, flow guide groove; 24, liquid inlet; 25, liquid outlet; 26, energy recovery device; 27, water pump; 28, thermometer; 261, hot water cavity; 262, cold water cavity; 263, semiconductor refrigeration piece; 264, first electromagnetic reversing valve; 265, second electromagnetic reversing valve. Detailed Implementation

[0018] Example 1

[0019] This embodiment provides a crystallization reactor for fermentation engineering, such as... Figure 1 As shown, the crystallization reactor used in this fermentation project mainly consists of a reactor body 1, an insulation cover 2, an observation window 3, a material inlet 4, a reducer 5, a motor 6, a frame-type agitator 7, and support legs 8. The reactor body 1 is made of stainless steel, which has good corrosion resistance. Its interior is used to hold the fermentation broth and other materials to be crystallized. The volume can be designed in different specifications according to actual production needs, such as the common 100L, 500L, and 1000L. The insulation cover 2 tightly wraps around the surface of the reactor body 1, providing insulation and reducing heat loss. Support legs 8 are fixedly installed on its sides by welding or other methods to support the entire crystallization reactor, ensuring its stable placement on the operating platform. The top of the insulation cover 2 is compatible with the top of the reactor body 1, without affecting the normal use of components such as the material inlet 4 and the observation window 3. The observation window 3 is located on the top of the crystallization vessel body 1 and is made of high-strength, high-temperature resistant, and corrosion-resistant quartz glass. It allows operators to observe the crystallization of the material inside the vessel in real time, including the growth morphology of the crystals and changes in the turbidity of the solution, providing a direct basis for process control.

[0020] The heat insulation cover 2 is equipped with guide vanes 21 and heating wires 22 inside. The guide vanes 21 are spiral-shaped and made of aluminum sheets, which are tightly attached to the inner wall of the heat insulation cover 2, forming a spiral guide groove 23 inside the heat insulation cover 2. The heating wires 22 are located between the guide vanes 21 and are made of materials with high resistance and high temperature resistance, such as nickel-chromium alloy. When energized, the heating wires 22 generate heat, which is evenly transferred along the surface of the reactor body 1 to the interior of the crystallization reactor body 1, ensuring uniform heating of the reactor body and avoiding local overheating or overcooling, thus providing a stable temperature environment for the crystallization process.

[0021] The insulation cover 2 has a liquid inlet 24 at the bottom and a liquid outlet 25 on the side. The liquid inlet 24 is used to introduce heat transfer media (such as hot water, hot oil, etc.), and the liquid outlet 25 is used to discharge the used media. In actual operation, a suitable heat transfer medium is selected according to the temperature required by the crystallization process. For example, when a higher temperature (80-150℃) is required, hot oil can be used. After the hot oil is heated to the set temperature by an external heating circulation system, it is injected into the insulation cover 2 through the liquid inlet 24, circulates along the guide plate 21, provides heat to the crystallizing kettle, and then is discharged from the liquid outlet 25, returning to the heating circulation system for reheating.

[0022] Example 2

[0023] Based on Example 1, such as Figure 2As shown, the energy recovery device 26 of the present embodiment includes a hot water cavity 261, a cold water cavity 262, a semiconductor refrigeration sheet 263, a first electromagnetic reversing valve 264, and a second electromagnetic reversing valve 265.

[0024] In the present embodiment, the hot water cavity 261 and the cold water cavity 262 are both made of stainless steel and have good heat insulation performance. The internal volume is designed according to the energy recovery requirement. Generally, the hot water cavity 261 is slightly larger than the cold water cavity 262 to accommodate the case where more hot medium is discharged from the heat preservation cover 2. The two cavities are separated by heat insulation material to ensure that heat is not transferred between them unless directional transfer is performed by the semiconductor refrigeration sheet 263.

[0025] The heating surface of the semiconductor refrigeration sheet 263 is attached to the hot water cavity 261, and the cooling surface is attached to the cold water cavity 262. When an electric current passes through, one side is heated and the other side is cooled using the Peltier effect of the semiconductor. During the cooling process of the crystallization kettle, the high-temperature hot medium discharged from the heat preservation cover 2 enters the hot water cavity 261, and the semiconductor refrigeration sheet 263 transfers heat to the heating surface, keeping the medium in the hot water cavity 261 at a high temperature. At the same time, the cooling surface lowers the temperature of the medium in the cold water cavity 262, reserving cold energy for possible subsequent cooling requirements.

[0026] The first electromagnetic reversing valve 264 and the second electromagnetic reversing valve 265: The first electromagnetic reversing valve 264 is connected to one end of the liquid outlet 25 and is used to control the flow direction of the hot medium after it is discharged from the heat preservation cover 2. According to system instructions, the hot medium can be directed to the hot water cavity 261 of the energy recovery device 26. The second electromagnetic reversing valve 265 is connected to the other end of the liquid inlet 24 and is used to control the source of the medium entering the heat preservation cover 2. The cold medium can be introduced from the cold water cavity 262 of the energy recovery device 26.

[0027] A thermometer 28 is connected in series on the connecting pipeline between the liquid outlet 25 and the energy recovery device 26: The thermometer 28 selects a high-precision thermocouple thermometer or thermistor thermometer to monitor the temperature of the hot medium discharged from the heat preservation cover 2 in real time and feed back the temperature signal to the control system. The control system automatically controls the working state of the first electromagnetic reversing valve 264, the second electromagnetic reversing valve 265, and the semiconductor refrigeration sheet 263 according to the temperature information to achieve efficient recovery and utilization of energy. For example, when the thermometer 268 detects that the temperature of the discharged hot medium is higher than the set energy recovery threshold (such as 50°C), the control system starts the energy recovery program, the first electromagnetic reversing valve 264 directs the hot medium into the hot water cavity 261 of the energy recovery device 26, and the semiconductor refrigeration sheet 263 is turned on to start heat transfer and cold energy storage. When the temperature of the hot medium is lower than the threshold, the water pump 27 does not work, and no energy recovery operation is performed. The heating wire 22 is used to heat the medium to warm the crystallization kettle body 1.

[0028] Through the above specific embodiments, the fermentation engineering crystallization kettle can ensure the smooth progress of the crystallization process while realizing efficient energy recovery and utilization, improving production efficiency, reducing production cost, and meeting the demand of the fermentation engineering field for crystallization equipment.

Claims

1. A fermentation engineering crystallization kettle comprising a crystallization kettle body, characterized in that: The surface of the crystallization kettle body is wrapped with a heat preservation cover, the top of the crystallization kettle body is respectively provided with an observation window and a material port, the top of the crystallization kettle body is provided with a motor, the output end of the motor is provided with a speed reducer, the speed reducer is fixedly installed on the top of the crystallization kettle body, the output end of the speed reducer is fixedly sleeved with a frame type stirrer, the side surface of the heat preservation cover is fixedly installed with supporting legs, the inside of the heat preservation cover is provided with flow guiding fins, and the inside of the heat preservation cover is provided with heating wires; the flow guiding fins are spiral-shaped, and the heating wires are located between the flow guiding fins; the bottom of the heat preservation cover is provided with a liquid inlet, the side surface of the heat preservation cover is provided with a liquid outlet, and the liquid inlet and the liquid outlet are connected in series with an energy recovery device and a water pump; the energy recovery device comprises a hot water cavity and a cold water cavity, a semiconductor refrigerating fin is arranged between the hot water cavity and the cold water cavity, the heating surface of the semiconductor refrigerating fin is attached to the hot water cavity, and the refrigerating surface of the semiconductor refrigerating fin is attached to the cold water cavity.

2. The crystallization kettle for fermentation engineering according to claim 1, characterized in that, The energy recovery device further comprises a first electromagnetic reversing valve and a second electromagnetic reversing valve, one end of the liquid outlet is connected with the first electromagnetic reversing valve, and the other end of the liquid inlet is connected with the second electromagnetic reversing valve.

3. The crystallization kettle for fermentation engineering according to claim 2, characterized in that, A thermometer is connected in series on the connecting pipeline of the liquid outlet and the energy recovery device.

Images