Large-volume water sample automatic loading solid-phase extraction device

Abstract

The utility model relates to the technical field of solid-phase extraction devices, in particular to a large-volume water sample automatic loading solid-phase extraction device which comprises a solid-phase extraction device main body, a solid-phase extraction column is arranged on the solid-phase extraction device main body, and a bottle with a cover for containing a large-volume water sample is arranged on the solid-phase extraction device main body. A bottle with a cap is arranged in the solid-phase extraction device main body, a disposable infusion apparatus is hermetically inserted into a bottle cap of the bottle with the cap, an infusion hose is arranged on the disposable infusion apparatus, a drip chamber, a particle filter, a flow regulator and an injection needle are sequentially mounted on the infusion hose from top to bottom, and a supporting base is arranged at the bottom of the solid-phase extraction device main body. The large-volume water sample automatic loading solid-phase extraction device can effectively reduce the manpower and material resource cost, the large-volume water sample is automatically loaded, the flow rate is controllable, pollution is avoided by disposable appliances, the volume of the water sample can be increased by serially connecting bottles, the detection efficiency is improved, and meanwhile, the blockage risk of the solid-phase extraction column is reduced by filtering particles.

Description

Technical Field

[0001] This utility model relates to the technical field of solid phase extraction devices, specifically an automatic solid phase extraction device for loading large volume water samples. Background Technology

[0002] When processing large volumes of water samples, especially in fields such as environmental monitoring, drinking water testing, or food safety, it is necessary to extract and concentrate trace amounts of target compounds from large volumes of water. Because the concentration of analytes in large volumes of water samples is low, solid-phase extraction is commonly used for enrichment, separation, and purification.

[0003] Existing solid-phase extraction (SPE) devices, such as the one disclosed in CN114558349A, allow for convenient control of the extract flow rate, improving detection accuracy. Furthermore, this SPE device reduces floor space, increases the amount of sample processed per unit time, and lowers detection costs. However, conventional SPE uses manual sample loading, which is time-consuming and labor-intensive. The SPE column is also prone to clogging, resulting in significant resource consumption. Fully automated SPE equipment, on the other hand, is more economically costly. Utility Model Content

[0004] The purpose of this invention is to provide an automatic solid-phase extraction device for large-volume water samples, in order to solve the problems mentioned in the background art, such as the need for manual sample loading in current solid-phase extraction devices on the market, which is time-consuming, labor-intensive, and prone to column clogging, resulting in high consumption of manpower and resources; and the high economic cost of using fully automatic solid-phase extraction equipment.

[0005] To achieve the above objectives, this utility model provides the following technical solution: an automatic solid-phase extraction device for large-volume water samples, comprising a solid-phase extraction device body, a solid-phase extraction column on the solid-phase extraction device body, a capped bottle for holding large-volume water samples on the solid-phase extraction device body, and a disposable infusion set sealed and inserted into the cap of the capped bottle, the disposable infusion set being provided with an infusion tubing, and a drip chamber, a particle filter, a flow regulator, and an injection needle being installed sequentially from top to bottom on the infusion tubing, a support base at the bottom of the solid-phase extraction device body, and limit rods evenly spaced at the upper end of the support base, with a waste liquid collection basin engaged between the limit rods, a solid-phase extraction column positioning plate placed above the waste liquid collection basin, and the solid-phase extraction column being inserted into the solid-phase extraction column positioning plate, a rubber stopper being tightly inserted into the upper end of the solid-phase extraction column, and the injection needle penetrating through the rubber stopper.

[0006] Preferably, the solid phase extraction device has a movable rod and a positioning rod that are movably connected and engaged with each other, and the positioning rod is welded to the support base. The bottom of the support base is also fixed with casters at even intervals by bolts.

[0007] Preferably, the movable rod is fitted with a first adjusting seat and a second adjusting seat, and the sides of the first adjusting seat and the second adjusting seat are fastened to the movable rod by through bolts.

[0008] Preferably, after the first adjusting seat is inserted into the side, the bolt is tightened into the positioning frame, and the positioning frame has an integrally bent ring forming a circular structure.

[0009] Preferably, the collar is fitted with positioning rings at even intervals, and the side of the positioning ring is fixed with fasteners forming an obtuse angle structure by screws, and the fasteners are in contact with the capped bottle respectively.

[0010] Preferably, a positioning plate is fixed to the side of the second adjustment seat by welding, and the particulate filter is engaged through the positioning plate.

[0011] Compared with existing technologies, the beneficial effects of this utility model are: the automatic solid-phase extraction device for large-volume water samples can effectively reduce labor and material costs, automatically load large-volume water samples, control the flow rate, use disposable equipment to avoid contamination, and connect bottles in series to increase the water sample volume and detection efficiency. Simultaneously, particle filtration reduces the risk of solid-phase extraction column clogging. This automatic solid-phase extraction device for large-volume water samples is used in conjunction with a disposable air-injection infusion set. Under atmospheric pressure and gravity, the large-volume water sample is placed at a high position, allowing the water sample to flow automatically through the infusion tubing, dropper, particle filter, flow regulator, and injection needle into the solid-phase extraction column with a rubber stopper, achieving the effect of automatic solid-phase extraction for large-volume water samples. Attached Figure Description

[0012] Figure 1 This is a schematic diagram of the structure of an automatic solid-phase extraction device for loading large volume water samples according to the present invention.

[0013] Figure 2 This is a schematic diagram of the structure of an automatic solid-phase extraction device for loading large volume water samples using fasteners to fix a bottle with a cap.

[0014] Figure 3 This is a top view of the fastener and collar connection structure of an automatic solid-phase extraction device for loading large volume water samples according to this utility model.

[0015] Figure 4 This is a schematic diagram of the structure of an automatic solid-phase extraction device for loading large-volume water samples, which uses a positioning plate to fix the solid-phase extraction column.

[0016] In the diagram: 1. Solid-phase extraction device body; 2. First adjustment seat; 201. Positioning frame; 202. Collar; 203. Positioning ring; 204. Fastener; 3. Movable rod; 4. Disposable infusion set; 401. Drip chamber; 402. Particulate filter; 403. Flow regulator; 404. Infusion tubing; 405. Injection needle; 5. Second adjustment seat; 501. Positioning plate; 6. Positioning rod; 7. Rubber stopper; 8. Solid-phase extraction column; 9. Support base; 901. Limiting rod; 902. Casters; 10. Bottle with cap; 11. Solid-phase extraction column positioning plate; 12. Waste liquid collection basin. Detailed Implementation

[0017] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0018] Please see Figure 1-4This utility model provides a technical solution: an automatic solid-phase extraction device for large-volume water samples, comprising a solid-phase extraction device body 1, a solid-phase extraction column 8 on the solid-phase extraction device body 1, a capped bottle 10 for holding large-volume water samples on the solid-phase extraction device body 1, and a disposable infusion set 4 sealed and inserted into the cap of the capped bottle 10. The disposable infusion set 4 is equipped with an infusion tubing 404, and the infusion tubing 404 is sequentially equipped with a drip chamber 401, a particle filter 402, a flow regulator 403, and an injection needle 405 from top to bottom. A support base 9 is provided at the bottom of the solid-phase extraction device body 1, and a movable rod 3 and a positioning rod 6 are provided on the solid-phase extraction device body 1 that are movably inserted and engaged with each other, and the positioning rod 6 is welded... On the support base 9, universal wheels 902 are evenly spaced and bolted to the bottom of the support base 9. This structure allows the solid phase extraction device body 1 to have a telescopic rod structure through the cooperation of the movable rod 3 and the positioning rod 6, which facilitates the lifting and adjustment of the solid phase extraction device body 1. The universal wheels 902 facilitate the movement and handling of the solid phase extraction device body 1. The movable rod 3 is fitted with a first adjusting seat 2 and a second adjusting seat 5, and the sides of the first adjusting seat 2 and the second adjusting seat 5 are fastened to the movable rod 3 by through bolts. This structure allows the first adjusting seat 2 and the second adjusting seat 5 to be adjusted in position on the movable rod 3. After the side of the first adjusting seat 2 is inserted, it is bolted to the positioning frame 201, and the positioning frame 201 is integrally bent to form a circle. The ring-shaped collar 202 allows the positioning frame 201 to be fixed to the movable rod 3 via the first adjusting seat 2. Limiting rods 901 are evenly spaced and inserted into the upper end of the supporting base 9, with a waste liquid collection basin 12 engaged between the limiting rods 901. A solid-phase extraction column positioning plate 11 is placed above the waste liquid collection basin 12, and the solid-phase extraction column 8 is inserted into the solid-phase extraction column positioning plate 11. Positioning rings 203 are evenly spaced and engaged on the collar 202. Fasteners 204 forming an obtuse angle structure are fixed to the side of the positioning rings 203 by screws, and the fasteners 204 contact and engage with the capped bottles 10. When positioning the capped bottles 10, the caps of the bottles 10 can be facing downwards, allowing the bottles 10 to be inserted... Inside the positioning ring 203, the lower part of the capped bottle 10 is supported by fasteners 204. Fasteners 204 rotate as the capped bottle 10 moves downwards, allowing another fastener 204 to clamp the side of the bottle body, thus achieving stable positioning of the capped bottle 10. This system can accommodate capped bottles 10 of various sizes. The capped bottle 10 is a clean bottle, and the cap provides a seal. A rubber stopper 7 is securely inserted into the upper end of the solid-phase extraction column 8, and the injection needle 405 passes through the rubber stopper 7. A positioning plate 501 is welded to the side of the second adjusting seat 5, and the particulate filter 402 engages and passes through the positioning plate 501. This structure allows the positioning plate 501 to reliably position the particulate filter 402.A large volume of water sample is drawn from a capped bottle 10 through the infusion tubing 404 of a disposable infusion set 4, passing sequentially through a drip chamber 401, a particle filter 402, a flow regulator 403, and an injection needle 405 before entering the solid-phase extraction column 8. This achieves rapid solid-phase extraction while simultaneously filtering solid impurities through the particle filter 402 to prevent clogging. The flow rate is controllable by the flow regulator 403. The disposable infusion set 4 is an air-inlet type, using disposable equipment to avoid contamination. Connecting the bottles in series increases the water sample volume and improves detection efficiency. The waste liquid collection basin 12 collects the waste liquid after solid-phase extraction, and the limiting rod 901 prevents the waste liquid collection basin 12 from tipping over.

[0019] Working principle: When using this large-volume water sample automatic solid-phase extraction device, the large-volume water sample is first loaded into the capped bottle 10. The movable rod 3 rises relative to the positioning rod 6. The height of the movable rod 3 is adjusted, and then the positions of the first adjusting seat 2 and the second adjusting seat 5 relative to the movable rod 3 are adjusted to control the positions of the positioning frame 201 and the positioning plate 501. The fixed position of the solid-phase extraction device body 1 is adjusted by the universal wheel 902. The waste liquid collection basin 12 is positioned on the support base 9 by the limiting rod 901. The solid-phase extraction column positioning plate 11 is placed on the waste liquid collection basin 12. Then, the solid-phase extraction column 8 is inserted into the solid-phase extraction column positioning plate 11. Next, the capped bottle 10 is inverted and inserted into the positioning ring 203. After the lower part of the capped bottle 10 is pressed against one of the fasteners 204, the collar 202 is positioned relative to the capped bottle 10 as it moves down. Ring 203 rotates until another fastener 204 clamps onto the side of the capped bottle 10. Then, the disposable infusion set 4 is inserted into the cap of the capped bottle 10. The other end of the disposable infusion set 4 is inserted into the rubber stopper 7 through the injection needle 405, thus connecting the solid phase extraction column 8 with the capped bottle 10. The particle filter 402 is positioned on the positioning plate 501. Under atmospheric pressure and gravity, the large volume of water sample in the capped bottle 10 flows through the infusion tubing 404, through the drip chamber 401, the particle filter 402, the flow regulator 403, and the injection needle 405 into the solid phase extraction column 8. This achieves automatic loading and solid phase extraction of the large volume of water sample. The flow rate can be controlled by the flow regulator 403, and the particle filter 402 filters out particulate impurities to prevent the solid phase extraction column 8 from clogging. This process is low in manpower and material costs, thus completing a series of tasks.

[0020] Although the present invention has been described in detail with reference to the foregoing embodiments, those skilled in the art can still modify the technical solutions described in the foregoing embodiments or make equivalent substitutions for some of the technical features. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present invention should be included within the protection scope of the present invention.

Claims

1. A large-volume water sample automatic loading solid phase extraction device, comprising a solid phase extraction device main body (1), a solid phase extraction column (8) is arranged on the solid phase extraction device main body (1), characterized in that: The solid phase extraction device body (1) is provided with a capped bottle (10) for containing a large volume of water sample, and the bottle cap of the capped bottle (10) is sealingly inserted with a disposable infusion set (4), the disposable infusion set (4) is provided with an infusion hose (404), and the infusion hose (404) is sequentially provided with a dropper (401), a particle filter (402), a flow regulator (403) and a injection needle (405) from top to bottom, the bottom of the solid phase extraction device body (1) is provided with a supporting base (9), the upper end of the supporting base (9) is uniformly and intervaliy inserted with a limiting rod (901), and the limiting rods (901) are clamped with a waste liquid collecting basin (12), the waste liquid collecting basin (12) is placed with a solid phase extraction column positioning disc (11) above, and the solid phase extraction column (8) is inserted into the solid phase extraction column positioning disc (11), the upper end of the solid phase extraction column (8) is tightly inserted with a rubber plug (7), and the injection needle (405) penetrates into the rubber plug (7).

2. The apparatus for automatic loading of large volume water samples for solid phase extraction according to claim 1, characterized in that: The solid phase extraction device body (1) is provided with a movable rod (3) and a positioning rod (6) which are movably inserted and matched with each other, and the positioning rod (6) is welded on the supporting base (9), and the supporting base (9) is further uniformly and intervaliy bolted with a universal wheel (902) at the bottom.

3. The apparatus according to claim 2, wherein: The movable rod (3) is sleeved with a first adjusting seat (2) and a second adjusting seat (5), and the first adjusting seat (2) and the second adjusting seat (5) are tightly matched with the movable rod (3) through penetrating bolts on the side.

4. The apparatus according to claim 3, wherein: The first adjusting seat (2) is rear bolted with a positioning frame (201) on the side, and the positioning frame (201) is integrally bent into a circular ring structure of a sleeve ring (202).

5. The apparatus for automatic loading of large volume water samples for solid phase extraction according to claim 4, wherein: The sleeve ring (202) is uniformly and intervaliy clamped with a positioning ring (203), and the positioning ring (203) is fixed with a fastener (204) which constitutes an obtuse angle structure on the side through a screw, and the fastener (204) and the capped bottle (10) are respectively contacted and matched.

6. The apparatus according to claim 3, wherein: The second adjusting seat (5) is fixed with a positioning clamping plate (501) on the side through welding, and the particle filter (402) is clamped and penetrated on the positioning clamping plate (501).

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