Ultrasonic cell crusher

Abstract

The utility model discloses an ultrasonic cell crusher, which belongs to the technical field of ultrasonic cell crushing and comprises a box body, a sealing plate is mounted on the box body in a sliding manner, a sound absorption plate is connected to the inner wall of the box body, a placement table is connected to the interior of the box body, a fixing plate is arranged above the box body, and the fixing plate is arranged on the box body. Electric push rods are fixedly mounted on the two sides of the upper portion of the box body through fixing plates, and the movable ends of the electric push rods are connected with mounting plates. According to the ultrasonic cell crusher, a worker places a beaker containing cells on a placement table and then rotates a threaded rod by screwing a hand wheel, at the moment, two movable blocks can oppositely move along the threaded rod through screw-thread fit of a guide sleeve and the threaded rod, a hinge rod is promoted to rotate, and therefore two clamping plates are pulled to oppositely move through the hinge rod; and meanwhile, the rubber pad can be attached to the beaker, so that friction is increased, and the beaker is prevented from sliding during ultrasonic crushing.

Description

Technical Field

[0001] This utility model belongs to the field of ultrasonic cell disruption technology, specifically an ultrasonic cell disruptor. Background Technology

[0002] An ultrasonic cell disruptor is a laboratory device that utilizes the cavitation effect generated by ultrasound in a liquid to apply impact force to the cell wall or tissue structure through mechanical vibration, thereby releasing and extracting cell components. It is widely used in biomedicine, drug development, food industry and other fields, and has the advantages of high efficiency, precision and multi-functionality.

[0003] Currently, when using an ultrasonic cell disruptor to disrupt cells, the beaker containing the cells is usually placed directly on the machine platform. This causes the beaker to slip during ultrasonic disruption, thus affecting the actual disruption process. Utility Model Content

[0004] To overcome the above-mentioned defects, this utility model provides an ultrasonic cell pulverizer, which solves the problem that placing a beaker containing cells directly on the machine platform can cause the beaker to slide during ultrasonic pulverization, thus affecting the actual pulverization process.

[0005] To achieve the above objectives, this utility model provides the following technical solution: an ultrasonic cell disruptor, comprising a housing, a sealing plate slidably mounted on the housing, a sound-absorbing plate connected to the inner wall of the housing, a placement platform connected inside the housing, a fixing plate provided above the housing, electric push rods fixedly mounted on both sides of the upper part of the housing via the fixing plates, an installation plate connected to the movable end of the electric push rods, an ultrasonic transducer mounted on the installation plate, and an ultrasonic generator mounted above the ultrasonic transducer;

[0006] An amplitude transformer is installed below the ultrasonic transducer. A threaded rod is rotatably connected inside the placement platform. One end of the threaded rod passes through the placement platform and is connected to a handwheel. Two movable blocks are installed on the threaded rod. Guide sleeves are installed on the movable blocks. Hinged rods are rotatably connected to both sides of the movable blocks via pins. One end of the hinged rod is rotatably connected to a clamping plate via a pin.

[0007] As a further embodiment of this utility model: a pull rod is connected above the sealing plate, an observation window is installed on the sealing plate, and connecting strips are connected to both sides of the sealing plate.

[0008] As a further embodiment of this utility model: connecting grooves are provided on both sides of the box body, and the connecting strip is slidably connected to the connecting grooves.

[0009] As a further embodiment of this utility model: the clamping plate slides inside the placement platform and one side is arc-shaped, and a rubber pad is connected to the arc-shaped surface on one side of the clamping plate.

[0010] As a further embodiment of this utility model: the two ends of the threaded rod are provided with threads in opposite directions, and the placement platform is internally connected with guide rods, two of which are respectively arranged on both sides below the threaded rod.

[0011] As a further embodiment of this utility model: the guide sleeve is threadedly engaged with the threaded rod, and the movable block is provided with a connecting hole, through which the movable block is slidably connected to the guide rod.

[0012] Compared with the prior art, the beneficial effects of this utility model are as follows:

[0013] 1. This ultrasonic cell disruptor, equipped with a handwheel, threaded rod, movable blocks, guide sleeve, hinge rod, clamping plates, and rubber pads, allows the operator to place a beaker containing cells on the placement platform. By turning the handwheel, the threaded rod rotates, causing two movable blocks to move in opposite directions along the threaded rod through the threaded engagement of the guide sleeve. This causes the hinge rod to rotate, pulling the two clamping plates in opposite directions, thus clamping and fixing the beaker in place. Simultaneously, the rubber pads adhere to the beaker, increasing friction and preventing the beaker from slipping during ultrasonic disruption.

[0014] 2. This ultrasonic cell disruptor is equipped with an electric push rod, a sound-absorbing plate, a sealing plate, a connecting strip, and a connecting groove. The operator pushes the connecting strip into the connecting groove, allowing the sealing plate to be installed and fixed on the chamber, thus sealing the chamber. Then, by activating the electric push rod, the mounting plate is moved down, causing the amplitude transformer to be inserted into the beaker. The ultrasonic transducer and ultrasonic generator are used to disrupt the cells. At this time, the sound-absorbing plate absorbs noise, thus achieving a sound insulation effect. Attached Figure Description

[0015] Figure 1 This is a schematic diagram of the three-dimensional structure of the present invention;

[0016] Figure 2 This is a schematic diagram of the cross-sectional structure of the box body of this utility model;

[0017] Figure 3 This is a schematic diagram of the cross-sectional structure of the placement platform of this utility model;

[0018] Figure 4 This is a schematic diagram of the three-dimensional structure of the clamping plate of this utility model;

[0019] Figure 5 This is a schematic diagram of the three-dimensional structure of the sealing plate of this utility model;

[0020] In the diagram: 1. Enclosure; 2. Sealing plate; 3. Sound-absorbing plate; 4. Placement platform; 5. Fixing plate; 6. Electric push rod; 7. Mounting plate; 8. Ultrasonic transducer; 9. Ultrasonic generator; 10. Amplitude transformer; 11. Threaded rod; 12. Handwheel; 13. Movable block; 14. Guide sleeve; 15. Hinge rod; 16. Clamping plate; 17. Pull rod; 18. Observation window; 19. Connecting strip; 20. Connecting groove; 21. Rubber pad; 22. Guide rod; 23. Connecting hole. Detailed Implementation

[0021] The technical solution of this patent will be further described in detail below with reference to specific embodiments.

[0022] like Figure 1-5 As shown, this utility model provides a technical solution: an ultrasonic cell disruptor, including a housing 1, a sealing plate 2 slidably installed on the housing 1, a sound-absorbing plate 3 connected to the inner wall of the housing 1, a pull rod 17 connected above the sealing plate 2, an observation window 18 installed on the sealing plate 2, and connecting strips 19 connected to both sides of the sealing plate 2. The observation window 18 allows the operator to observe the cell disruption in the housing 1 in real time, and by installing the sealing plate 2 on the housing 1, the housing 1 can be sealed, thereby absorbing and isolating noise through the sound-absorbing plate 3.

[0023] The box 1 is connected to a placement platform 4 inside. Connecting grooves 20 are opened on both sides of the box 1. Connecting strips 19 are slidably connected to the connecting grooves 20. By sliding the connecting strips 19 in the connecting grooves 20, the staff can quickly complete the positioning and installation of the sealing plate 2, thereby completing the sealing of the box 1.

[0024] A fixing plate 5 is installed on the top of the box 1. Electric push rods 6 are fixedly installed on both sides of the top of the box 1 through the fixing plate 5. The movable end of the electric push rod 6 is connected to the mounting plate 7. An ultrasonic transducer 8 is installed on the mounting plate 7. An ultrasonic generator 9 is installed above the ultrasonic transducer 8. An amplitude transformer 10 is installed below the ultrasonic transducer 8. A threaded rod 11 is rotatably connected inside the placement platform 4. The two ends of the threaded rod 11 are provided with threads in opposite directions. A guide rod 22 is connected inside the placement platform 4. There are two guide rods 22, which are respectively set on both sides below the threaded rod 11. When the threaded rod 11 drives the movable block 13 to move, the movable block 13 will slide along the guide rod 22, thereby guiding the movement of the movable block 13 through the guide rod 22 and preventing the movable block 13 from rotating and tilting during movement.

[0025] One end of the threaded rod 11 passes through the placement platform 4 and is connected to a handwheel 12. Two movable blocks 13 are installed on the threaded rod 11, and guide sleeves 14 are installed on the movable blocks 13. The guide sleeves 14 are threadedly engaged with the threaded rod 11. A connecting hole 23 is provided on the movable block 13. The movable block 13 is slidably connected to the guide rod 22 through the connecting hole 23. Through the threaded engagement between the guide sleeve 14 and the threaded rod 11 and the opposite threads at both ends of the threaded rod 11, the two movable blocks 13 can move in opposite directions along the threaded rod 11, thereby enabling the hinge rod 15 to pull the clamping plate 16 to move, so as to clamp and fix beakers of different sizes.

[0026] The movable block 13 is rotatably connected to the hinge rod 15 on both sides by a pin. One end of the hinge rod 15 is rotatably connected to the clamping plate 16 by a pin. The clamping plate 16 slides inside the placement platform 4 and has an arc-shaped design on one side. A rubber pad 21 is connected to the arc-shaped surface on one side of the clamping plate 16. When the clamping plate 16 contacts the beaker, the rubber pad 21 will be squeezed and deformed, thus making it fit in close contact with the beaker, increasing the friction between the clamping plate 16 and the beaker, and preventing slippage.

[0027] The working principle of this utility model is as follows:

[0028] The operator places a beaker containing cells on the placement platform 4, then turns the handwheel 12 to rotate the threaded rod 11. This causes two movable blocks 13 to move in opposite directions along the threaded rod 11 through the guide sleeve 14 and the threaded engagement of the threaded sleeve 14. This causes the hinge rod 15 to rotate, which in turn pulls the two clamping plates 16 to move in opposite directions, allowing the clamping plates 16 to hold and fix the beaker in place. At the same time, the rubber pad 21 will adhere to the beaker, thereby increasing friction and preventing the beaker from sliding during ultrasonic pulverization. Then, the connecting strip 19 is pushed into the connecting groove 20, allowing the sealing plate 2 to be installed and fixed on the housing 1, thus sealing the housing 1. Then, the electric push rod 6 is activated to push the mounting plate 7 down, allowing the amplitude transformer 10 to be inserted into the beaker. The ultrasonic transducer 8 and ultrasonic generator 9 are then used to pulverize the cells, while the sound-absorbing plate 3 absorbs and reduces noise.

[0029] In the description of this utility model, it should be noted that, unless otherwise explicitly specified and limited, the terms "installation," "connection," and "joining" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; and they can refer to the internal connection of two components. Those skilled in the art can understand the specific meaning of the above terms in this utility model based on the specific circumstances.

[0030] The preferred embodiments of this patent have been described in detail above. However, this patent is not limited to the above embodiments. Within the scope of knowledge possessed by those skilled in the art, various changes can be made without departing from the spirit of this patent.

Claims

1. An ultrasonic cell disruptor, comprising a housing (1), characterized in that: A sealing plate (2) is slidably installed on the box (1), a sound-absorbing plate (3) is connected to the inner wall of the box (1), a placement platform (4) is connected inside the box (1), a fixing plate (5) is set on the top of the box (1), electric push rods (6) are fixedly installed on both sides of the top of the box (1) through the fixing plate (5), an installation plate (7) is connected to the movable end of the electric push rod (6), an ultrasonic transducer (8) is installed on the installation plate (7), and an ultrasonic generator (9) is installed above the ultrasonic transducer (8); An amplitude transformer (10) is installed below the ultrasonic transducer (8). A threaded rod (11) is rotatably connected inside the placement platform (4). One end of the threaded rod (11) passes through the placement platform (4) and is connected to a handwheel (12). Two movable blocks (13) are installed on the threaded rod (11). A guide sleeve (14) is installed on the movable block (13). A hinge rod (15) is rotatably connected to both sides of the movable block (13) through a pin. One end of the hinge rod (15) is rotatably connected to a clamping plate (16) through a pin.

2. The ultrasonic cell disruptor according to claim 1, characterized in that: A pull rod (17) is connected above the sealing plate (2), an observation window (18) is installed on the sealing plate (2), and connecting strips (19) are connected to both sides of the sealing plate (2).

3. The ultrasonic cell disruptor according to claim 2, characterized in that: The box body (1) has connecting grooves (20) on both sides, and the connecting strip (19) is slidably connected to the connecting grooves (20).

4. The ultrasonic cell disruptor according to claim 1, characterized in that: The clamp (16) slides inside the placement platform (4) and has an arc-shaped design on one side. A rubber pad (21) is connected to the arc-shaped surface on one side of the clamp (16).

5. The ultrasonic cell disruptor according to claim 1, characterized in that: The threaded rod (11) has threads in opposite directions at both ends. The placement platform (4) is connected to a guide rod (22). There are two guide rods (22) respectively located on both sides below the threaded rod (11).

6. The ultrasonic cell disruptor according to claim 5, characterized in that: The guide sleeve (14) is threadedly engaged with the threaded rod (11), and the movable block (13) is provided with a connecting hole (23). The movable block (13) is slidably connected to the guide rod (22) through the connecting hole (23).

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