Amino acid removing device
By designing an amino acid removal device that includes components such as a processing tank and an exchange column, the problems of incomplete amino acid removal and low detection precision in the existing technology are solved, achieving efficient and convenient amino acid removal and detection, and reducing costs.
Patent Information
- Application Number
- CN202520625038.1
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2025-04-03
- Publication Date
- 2026-03-06
- Estimated Expiration
- 2035-04-03
AI Technical Summary
Existing technologies lack effective and convenient devices and methods to remove amino acids from compound amino acid injections, resulting in overly high detection results, poor precision, and difficulties in activating the exchange resin, leading to low utilization and high costs.
An amino acid removal device was designed, including a treatment tank, an exchange column, a connector, a hose, a liquid addition pipe, and a flow control sleeve. Through threaded connection and a sealed design, convenient liquid filling and exchange adsorption are achieved, ensuring complete removal of amino acids, improving detection precision and device convenience.
It achieves complete elution of amino acids, improves the accuracy and precision of detection results, simplifies the operation process, reduces manpower and material costs, and the device can be reused.
Smart Images
Figure CN223969535U_ABST
Abstract
Description
Technical Field
[0001] This utility model relates to the field of reaction removal technology, specifically to an amino acid removal device. Background Technology
[0002] Compound amino acid injection is mainly used for patients whose amino acid intake is insufficient or who have malabsorption disorders, resulting in insufficient amino acid intake to meet the body's metabolic needs. Different prescription dosages of compound amino acid injection correspond to different indications. Compound amino acid injection (18AA) is mainly suitable for patients whose amino acid intake is insufficient or who have malabsorption disorders, resulting in insufficient amino acid intake to meet the body's metabolic needs, and is also used to improve the nutritional status of postoperative patients. It is suitable for patients who generally need amino acid supplementation. Compound amino acid injection (18AA-Ⅳ), because it contains glucose, is suitable for diabetic patients who need amino acid supplementation. Because sorbitol is added to the prescription of compound amino acid injection (18AA), the sorbitol content needs to be tested. According to the quality standard testing methods included in the Chinese Pharmacopoeia, the sample needs to be treated to remove amino acids before content titration. Similarly, because glucose is added to the prescription of compound amino acid injection (18AA-Ⅳ), the glucose content needs to be tested.
[0003] Currently, there is no equipment or device on the market that can effectively and conveniently remove amino acids from compound amino acid injections. Moreover, this process is quite complex and requires 2-3 people to work together to complete. In addition, during the process, not all amino acids are completely adsorbed and some are eluted, resulting in higher results for sorbitol or glucose determination, poor precision, and inability to properly assess the true quality of the product. Furthermore, the exchange resin is difficult to reactivate after use, and it is difficult to reuse due to the lack of adaptation devices, resulting in low utilization and high cost.
[0004] Therefore, in order to solve the above problems, an amino acid removal device is proposed. Utility Model Content
[0005] The purpose of this invention is to provide an amino acid removal device to solve the problems mentioned in the background art.
[0006] To achieve the above objectives, the present invention provides the following technical solution: an amino acid removal device, comprising a processing tank, an exchange column assembled inside the processing tank, a connector threaded to the upper end of the processing tank, a hose threaded to the top of the connector, a liquid addition pipe threaded to the lower right end of the hose, a filter chamber threaded to the outlet end of the liquid addition pipe, a flow control sleeve fitted in the middle of the hose, and a support frame mounted on the rear side of the processing tank and the hose.
[0007] As a further step of this solution, an upper septum and a lower septum are respectively provided on the upper and lower parts of the exchange column, and the upper septum, the exchange column and the lower septum are sequentially inserted and assembled inside the processing tank.
[0008] As a further step of this solution, a drain trough is integrally provided at the bottom of the treatment tank, and a cap is threaded onto the lower part of the drain trough. A torsion block is fixed at the bottom of the cap, and the torsion block is cross-shaped.
[0009] As a further step of this solution, the top of the connector is integrally fixed with a left socket, and both ends of the hose are integrally provided with a left plug and a right plug corresponding to the left socket. The top of the filter chamber and the top of the liquid filling pipe are respectively fixed with a lower socket and an upper socket similar to the left socket, and the bottom of the filter chamber is equipped with a lower plug similar to the right plug.
[0010] As a further improvement of this solution, the filter chamber is configured as two hollow hemispheres, and the upper and lower hemispheres of the filter chamber are connected by threads. The filter chamber is equipped with a corresponding filter screen. An inner push rod is inserted into the bottom of the liquid filling tube, and an inner rubber plug is fixed at the upper end of the inner push rod. The liquid filling tube is transparent, and corresponding scale lines are engraved on the outer wall of the liquid filling tube.
[0011] As a further step of this solution, an inner ball is provided in the center of the flow control sleeve, and the lower convex arc end of the inner ball abuts against the outer wall of the hose. An inner threaded pin is fixed on the side of the inner ball, and the inner threaded pin is threaded into the outer wall of the flow control sleeve. External studs are threaded into the outer sides of both the upper and lower ends of the flow control sleeve. An inner clamp is assembled at the inner end of the external stud through the sleeve shell. The inner wall of the inner clamp wraps around the outer wall of the hose. A card is fixed inside the sleeve shell and fixed to the inner end of the external stud. A torsion cap is fixed at the outer end of the external stud.
[0012] As a further step of this solution, a support clamp is installed on the rear side of the treatment tank, and a support clamp is supported on the outer wall of the hose. An installation plate is installed on the rear side of the support clamp and the support clamp. The installation plate is fixed to the upper end of the upright frame, and a base is supported at the bottom of the upright frame. Reinforcing ribs are supported on the surface of the base and the bottom of the upright frame.
[0013] Compared with the prior art, the beneficial effects of this utility model are: this utility model can make the amino acids in the compound amino acid injection solution be eluted, the content detection results of sorbitol or glucose are true and effective with good precision, can well evaluate product quality, and is simple to operate, easy to clean, can be reused, can save manpower and material resources, and has low overall cost.
[0014] 1. This utility model, by incorporating an exchange column within the treatment tank, facilitates the filling and guiding of liquid through the cooperation of the connector, hose, and liquid inlet pipe. The process of liquid introduction is more convenient, and the flow between the treatment tank and the exchange column is easier, promoting thorough exchange and adsorption to achieve complete amino acid removal. This results in more accurate subsequent testing, facilitating product quality assessment with good precision. This design enhances the convenience and practicality of the amino acid removal device.
[0015] 2. This utility model is equipped with a treatment tank, connector, hose, and liquid addition pipe. During assembly and use, it is assembled by threaded insertion, and the entire process is relatively sealed, which makes it less likely to cause infection. At the same time, it can be inserted after use, making the cleaning operation more convenient. With the cooperation of the flow control sleeve, it is also convenient to assist in controlling the flow during the liquid addition pipe pushing process, making the operation and use more convenient. Through this design, the convenience and practicality of the amino acid removal device are improved. Attached Figure Description
[0016] Figure 1 This is a frontal perspective three-dimensional schematic diagram of the overall structure of this utility model;
[0017] Figure 2 This is a bottom-view perspective view of the overall structure of this utility model;
[0018] Figure 3 This is a three-dimensional front view sectional view of a partial structure of the treatment tank of this utility model;
[0019] Figure 4 This is a frontal exploded view of a portion of the liquid filling tube of this utility model.
[0020] Figure 5 This is a three-dimensional front view sectional view of a partial structure of the flow control sleeve of this utility model;
[0021] In the diagram: 100, Treatment tank; 101, Drainage trough; 102, Cover; 103, Twist block; 110, Exchange column; 111, Upper septum; 112, Lower septum; 120, Connector; 121, Left socket; 130, Hoses; 131, Left plug; 132, Right plug; 140, Filling pipe; 141, Lower socket; 142, Inner push rod; 143, Inner rubber stopper; 150, Filter chamber; 151, Upper socket; 152, Lower plug; 160, Flow control sleeve; 161, Inner ball; 162, Inner threaded pin; 163, Outer stud; 164, Inner clamp; 165, Housing; 166, Clip; 167, Twist cap; 170, Support clamp; 171, Support clamp; 172, Mounting plate; 180, Stand; 181, Base; 182, Reinforcing rib. Detailed Implementation
[0022] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.
[0023] Please see Figures 1-5 One embodiment provided by this utility model:
[0024] An amino acid removal device includes a processing tank 100, an exchange column 110 inside the processing tank 100, a connector 120 threadedly mounted on the upper end of the processing tank 100, a hose 130 threadedly mounted on the top of the connector 120, a liquid inlet pipe 140 threadedly mounted on the lower right side of the hose 130, a filter chamber 150 threadedly mounted on the outlet end of the liquid inlet pipe 140, a flow control sleeve 160 sleeved in the middle of the hose 130, and a support frame 180 mounted on the rear side of the processing tank 100 and the hose 130.
[0025] As described in more detail in this embodiment, the exchange column 110 is provided with an upper septum 111 and a lower septum 112 at the top and bottom, respectively. The upper septum 111, the exchange column 110 and the lower septum 112 are sequentially inserted and assembled inside the treatment tank 100. This facilitates the assistance of the exchange column 110 during use. The exchange column 110 is made of resin, the upper septum 111 and the lower septum 112 are both made of degreased cotton, the hose 130 is made of PVC, the inner rubber stopper 143 is made of rubber, the filter chamber 150 is made of any one of PES, nylon or MCE, and the rest are made of PP.
[0026] As more detailed in this embodiment, the bottom of the treatment tank 100 is integrally provided with a drain trough 101, and a cover 102 is threadedly fitted on the lower part of the drain trough 101. A twist block 103 is fixedly provided at the bottom of the cover 102, and the twist block 103 is cross-shaped, so as to facilitate the auxiliary drainage of the solution after the exchange removal, making the operation and use more convenient.
[0027] As described in more detail in this embodiment, the top of the connector 120 is integrally provided with a left socket 121, and both ends of the hose 130 are integrally provided with a left plug 131 and a right plug 132 corresponding to the left socket 121. The top of the filter chamber 150 and the top of the liquid filling tube 140 are respectively provided with a lower socket 141 and an upper socket 151 similar to the left socket 121. The bottom of the filter chamber 150 is equipped with a lower plug 152 similar to the right plug 132. In this way, it is convenient to connect and assemble the connector 120, hose 130, liquid filling tube 140 and filter chamber 150 during use, making the docking assembly more convenient.
[0028] As described in more detail in this embodiment, the filter chamber 150 is configured as two hollow hemispheres, and the upper and lower hemispheres of the filter chamber 150 are connected by threads. A corresponding filter screen is installed inside the filter chamber 150. An inner push rod 142 is inserted into the bottom of the liquid addition tube 140, and an inner rubber stopper 143 is fixed at the upper end of the inner push rod 142. The liquid addition tube 140 is transparent, and corresponding scale lines are engraved on the outer wall of the liquid addition tube 140. In this way, it is convenient to assist in pushing the solution and initial filtration during assembly and use, and to avoid subsequent clogging. At the same time, the liquid addition tube 140 can also be replaced with a peristaltic pump or other delivery tool during use.
[0029] As described in more detail in this embodiment, an inner ball 161 is provided in the center of the flow control sleeve 160, and the lower convex arc end of the inner ball 161 abuts against the outer wall of the hose 130. An inner threaded pin 162 is fixed on the side of the inner ball 161, and the inner threaded pin 162 is threaded into the outer wall of the flow control sleeve 160. An outer stud 163 is threaded into the outer sides of both the upper and lower ends of the flow control sleeve 160. An inner clamp 164 is assembled at the inner end of the outer stud 163 through the sleeve 165. The inner wall of the inner clamp 164 wraps around the outer wall of the hose 130. A card 166 is clamped inside the sleeve 165 and is fixed to the inner end of the outer stud 163. A torsion cap 167 is fixed at the outer end of the outer stud 163. In this way, during use, it is convenient to clamp the hose 130 through the inner ball 161 and the inner threaded pin 162, so that the internal flow can be easily controlled. It is also convenient to limit the assembly between the flow control sleeve 160 and the hose 130, making subsequent use more convenient.
[0030] As described in more detail in this embodiment, a support clamp 170 is installed on the rear side of the treatment tank 100, and a support clamp 171 is supported on the outer wall of the hose 130. A mounting plate 172 is installed on the rear side of the support clamp 170 and the support clamp 171. The mounting plate 172 is fixed to the upper end of the stand 180, and a base 181 is supported at the bottom of the stand 180. Reinforcing ribs 182 are supported on the surface of the base 181 and the bottom of the stand 180. In this way, it is convenient to assemble and support the treatment tank 100 and the hose 130 during use, making subsequent operation more convenient.
[0031] Working Principle: Before use, the delivery components can be selected according to the needs of use. Manual pushing can be achieved using the liquid addition pipe 140, or it can be replaced with an electric pump such as a peristaltic pump. The treatment tank 100, connector 120, hose 130, liquid addition pipe 140, filter chamber 150, and flow control sleeve 160 are assembled sequentially, followed by pre-rinsing. Then, the upper septum 111, exchange column 110, and lower septum 112 are inserted and assembled inside the treatment tank 100. A certain amount of sodium sulfonate cation exchange resin is filled into the exchange column 110. The treatment tank 100 and connector 120 are reconnected. Then, a specified solution is drawn through the liquid addition pipe 140 to neutralize the exchange resin. After neutralization is detected... Reopen connector 120, add a certain amount of sample solution according to standard requirements, tighten connector 120, and then close flow control sleeve 160. That is, tighten inner screw pin 162 so that inner ball 161 contacts tubing 130 for secure sealing, which helps to maintain relative closure. Then, draw in a certain volume of eluent through liquid addition tube 140. If necessary, loosen inner screw pin 162 and inner ball 161 so that tubing 130 can pass a certain amount of liquid. Then, push inner push rod 142 at a uniform speed and adjust different elution speeds through flow control sleeve 160 to achieve the required 1.5ml to 2ml per minute. Then, use a certain volume of eluent to quickly elute to fully adsorb and remove amino acids. Collect the eluent for subsequent content titration.
[0032] During operation, the entire elution process is sealed, which reduces the risk of contamination during elution. At the same time, the assembly of the filter chamber 150 reduces the risk of impurities or foreign objects entering the eluent. After use, it is easy to disassemble and clean, and can be reused. After removing amino acids, a specific liquid can be directly added for resin activation. It can be reused repeatedly, saving costs. The operation ends here.
[0033] The above description is merely a preferred embodiment of this utility model and is not intended to limit the utility model in any way. Those skilled in the art can readily implement this utility model based on the accompanying drawings and the above description. However, any modifications, alterations, or equivalent variations made by those skilled in the art without departing from the scope of the utility model's technical solution, utilizing the disclosed technical content, are considered equivalent embodiments of this utility model. Furthermore, any equivalent changes, alterations, or variations made to the above embodiments based on the essential technology of this utility model are still within the protection scope of this utility model's technical solution.
Claims
1. An apparatus for removing amino acids, comprising a treatment tank (100), characterized in that: The processing tank (100) is internally provided with an exchange column (110), the upper end of the processing tank (100) is threadedly provided with a connecting head (120), the top of the connecting head (120) is threadedly provided with a hose (130), the lower end of the right side of the hose (130) is threadedly provided with a liquid adding pipe (140), the outlet end of the liquid adding pipe (140) is threadedly provided with a filter bin (150), the middle of the hose (130) is sleevedly provided with a flow control sleeve (160), and the rear side of the processing tank (100) and the hose (130) is supportingly provided with a stand (180).
2. The apparatus of claim 1, wherein: The upper and lower sides of the exchange column (110) are respectively provided with an upper spacer (111) and a lower spacer (112), and the upper spacer (111), the exchange column (110) and the lower spacer (112) are sequentially inserted and arranged in the inside of the processing tank (100).
3. The apparatus of claim 1, wherein: The bottom of the processing tank (100) is integrally provided with a liquid discharge groove (101), the lower part of the liquid discharge groove (101) is threadedly sleeved with a cover (102), the bottom of the cover (102) is fixedly provided with a torsion block (103), and the torsion block (103) is in a cross shape.
4. The apparatus of claim 1, wherein: The top of the connecting head (120) is integrally fixedly provided with a left socket (121), both ends of the hose (130) are integrally provided with a left plug (131) and a right plug (132) corresponding to the left socket (121), the top of the filter bin (150) and the top of the liquid adding pipe (140) are respectively fixedly provided with a lower socket (141) and an upper socket (151) same as the left socket (121), and the bottom of the filter bin (150) is provided with a lower plug (152) same as the right plug (132).
5. The apparatus of claim 1, wherein: The filter bin (150) is provided in a two hollow hemispherical shape, the middle parts of the two hemispheres of the filter bin (150) are connected through threads, the inside of the filter bin (150) is provided with a corresponding filter screen, the bottom of the liquid adding pipe (140) is insertedly provided with an inner push rod (142), the upper end of the inner push rod (142) is fixedly provided with an inner rubber plug (143), the liquid adding pipe (140) is provided in a transparent manner, and the outer wall of the liquid adding pipe (140) is engraved with corresponding scale lines.
6. The apparatus of claim 1, wherein: The inside of the flow control sleeve (160) is centrally provided with an inner abutting ball (161), the lower convex arc end of the inner abutting ball (161) abuts against the outer wall of the hose (130), the side edge of the inner abutting ball (161) is fixedly provided with an inner screw pin (162), the inner screw pin (162) is threadedly inserted in the outer wall of the flow control sleeve (160), the outer sides of the upper and lower ends of the flow control sleeve (160) are threadedly inserted with outer screw columns (163), the inner ends of the outer screw columns (163) are assembled with inner clamping cards (164) through sleeve shells (165), the inner walls of the inner clamping cards (164) are wrapped around the outer wall of the hose (130), the inside of the sleeve shell (165) is clamped with a card (166), the card (166) is fixed to the inner end of the outer screw column (163), and the outer end of the outer screw column (163) is fixedly provided with a twist cap (167).
7. The apparatus of claim 1, wherein: The processing tank (100) rear side is equipped with a support hoop (170), the outer wall of the hose (130) is supported with a support clamp (171), the rear side of the support hoop (170) and the support clamp (171) is supported with a mounting plate (172), the mounting plate (172) is fixed on the upper end of a stand (180), and the bottom of the stand (180) is supported with a base (181), and the surface of the base (181) and the bottom of the stand (180) are both supported with a reinforcing rib (182).