Polymer microsphere storage device
By designing a cylindrical cam and an electric actuator to drive the storage box to rotate, and combining a toothed gear and a cam to control the timed rotation and oscillation of the storage box, the problem of microparticle precipitation in the microsphere storage device was solved, and the uniform dispersion of drugs and the stability of therapeutic effects were achieved.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2025-04-25
- Publication Date
- 2026-03-06
AI Technical Summary
Existing microsphere storage devices are prone to microparticle sedimentation after standing, requiring re-shaking or dispersing before use, which affects the uniformity of drug release and therapeutic effect.
A polymer microsphere storage device was designed, which uses a cylindrical cam and an electric actuator to drive the storage box to rotate. Combined with a toothed gear and a cam to control the timed rotation and oscillation of the storage box, the microspheres are uniformly dispersed in the drug solution.
This achieves uniform dispersion of microspheres in the drug solution, reduces precipitation, ensures accurate drug dosage each time, and guarantees consistent treatment effects.
Smart Images

Figure CN223973026U_ABST
Abstract
Description
Technical Field
[0001] This utility model relates to the field of microsphere storage technology, and specifically to a polymer microsphere storage device. Background Technology
[0002] Polymer microspheres are spherical microparticles made from synthetic or natural polymer materials, typically with particle sizes in the micrometer range or even smaller, and are composed of polymeric molecules. Currently, in pharmaceutical science, microspheres are defined as tiny spherical entities formed when drugs are dissolved or dispersed in polymeric materials; they are spherical or near-spherical and are generally prepared as suspensions for injection or oral administration. However, when these medications are left to stand, the microparticles tend to settle to the bottom, leading to uneven drug release and affecting therapeutic efficacy.
[0003] Patent CN 222117667 U discloses an in vitro diagnostic microsphere storage device, including a housing, a storage box fixedly connected to the inner wall of the housing, a partition slidably connected to the outer wall of the storage box, a storage reagent disposed inside the storage box, a limiting plate movably connected between the storage boxes, a door hinged to the housing, and a rotating pushing device disposed inside the storage box, the rotating pushing device including a positioning block.
[0004] However, the device still has the following problems: it cannot prevent microsphere precipitation when storing the preparation. If precipitation occurs during use, the preparation needs to be shaken or dispersed again, which is time-consuming and laborious. Utility Model Content
[0005] To address the problems existing in the prior art, a polymer microsphere storage device is provided to solve the problems mentioned in the background.
[0006] The technical solution adopted by this utility model to solve its technical problem is:
[0007] This utility model proposes a polymer microsphere storage device, including a support, a rotating shaft rotatably connected to the support, a storage box fixedly connected to the rotating shaft, a cylindrical cam fixedly connected to the rotating shaft, the cylindrical cam having a sliding groove, an electric push rod provided on the support, and a sliding rod connected to the end of the electric push rod, the sliding rod being slidably disposed within the sliding groove.
[0008] Preferably, the bracket is equipped with a motor, the motor is directly connected to a toothed gear, a first gear that cooperates with the toothed gear is fixedly sleeved on the rotating shaft, and the two ends of the slide groove are connected to swing grooves for the slide rod to slide.
[0009] Preferably, the bracket is fixed with a switch that controls the forward and reverse rotation of the electric actuator, and the bracket has a cam that cooperates with the switch.
[0010] Preferably, a drive shaft is rotatably connected to the bracket, and the cam is fixedly sleeved on the drive shaft; the drive shaft is also fixedly sleeved with a second gear, which meshes with the toothed gear.
[0011] Preferably, the drive shaft and the bracket are fixed together by a one-way bearing.
[0012] Preferably, the storage box has several storage slots, and the storage slots are slidably connected to clamps, which are fixed to the storage box by compression springs.
[0013] Preferably, the storage box is detachably connected to a lid.
[0014] Preferably, the top of the clamping plate extends outward to form a guide portion.
[0015] Preferably, a counterweight is slidably connected to the side of the storage box.
[0016] Preferably, the storage box is provided with an insulation layer.
[0017] Compared with the prior art, the beneficial effects of this utility model are:
[0018] 1. This utility model is equipped with a cylindrical cam and an electric actuator. The electric actuator is fixed and moves in and out of the room. When the electric actuator extends or retracts, it drives the slide bar to slide in the groove of the cylindrical cam, thereby driving the cylindrical cam to rotate. The cylindrical cam drives the storage box to flip over through the rotating shaft, causing the storage box to be inverted. At this time, the microspheres placed in the storage box will also be inverted, which is conducive to the uniform dispersion of microspheres in the drug solution and reduces the formation of sediment. Therefore, when the drug solution is extracted for use, the drug dosage obtained each time is accurate, ensuring the consistency of the treatment effect.
[0019] 2. This utility model is equipped with a toothed gear. When the toothed gear meshes with the first gear, it can drive the storage box to rotate through the rotating shaft. When the toothed gear disengages from the first gear, the storage box swings back under the action of gravity. The toothed gear continues to rotate, constantly meshing with the first gear and then disengaging, causing the storage box to swing continuously. This makes the force on the microspheres in the liquid more uniform and constantly changing, thus maintaining a uniformly dispersed state in the bottle.
[0020] 3. This utility model is equipped with a cam, which is driven by a motor to rotate, so that the cam continuously contacts and disengages from the switch, thereby controlling the extension and retraction of the electric push rod to realize the timed flipping of the storage box, so that the internal suspension can be inverted at a timed interval. Attached Figure Description
[0021] The above and / or additional aspects and advantages of this utility model will become apparent and readily understood from the description of the embodiments taken in conjunction with the following drawings, in which:
[0022] Figure 1 This is a perspective view of the present invention;
[0023] Figure 2 This is a front view of the present invention;
[0024] Figure 3 This is a cross-sectional view of the storage box of this utility model;
[0025] Figure 4 This is the unfolded view of the cylindrical cam of this utility model;
[0026] Figure 5 This is a schematic diagram of the switch of this utility model.
[0027] Explanation of reference numerals in the attached figures:
[0028] 1. Bracket; 2. Shaft; 3. Storage box; 4. Cylindrical cam; 5. Slide groove; 6. Electric actuator; 7. Slide rod; 8. Motor; 9. Gear with missing tooth; 10. First gear; 11. Swing groove; 12. Switch; 13. Cam; 14. Drive shaft; 15. Second gear; 16. Clamping plate; 17. Compression spring; 18. Box cover; 19. Counterweight; 20. Insulation layer; 21. Spring; 22. Conductive contact. Detailed Implementation
[0029] The embodiments of this utility model are described in detail below. Examples of these embodiments are shown in the accompanying drawings, wherein the same or similar reference numerals denote the same or similar elements or elements having the same or similar functions throughout. The embodiments described below with reference to the accompanying drawings are exemplary and are only used to explain this utility model, and should not be construed as limiting this utility model.
[0030] like Figures 1-5 As shown, this embodiment proposes a polymer microsphere storage device, including a support 1, a rotating shaft 2 rotatably connected to the support 1, a storage box 3 fixedly connected to the rotating shaft 2, a cylindrical cam 4 fixedly connected to the rotating shaft 2, the cylindrical cam 4 having a sliding groove 5, an electric push rod 6 fixedly mounted on the support 1, a sliding rod 7 connected to the end of the electric push rod 6, and the sliding rod 7 slidingly disposed in the sliding groove 5.
[0031] The slide rod 7 is rotatably sleeved on the end of the electric push rod 6. Since the electric push rod 6 is fixed on the bracket 1, when the electric push rod 6 extends or retracts, it drives the slide rod 7 to slide in the slide groove 5. Therefore, the slide rod 7 drives the cylindrical cam 4 to rotate through the relative sliding with the slide groove 5. The cylindrical cam 4 is coaxially fixed with the rotating shaft 2, thereby driving the rotating shaft 2 and the storage box 3 to rotate.
[0032] Each time the slide bar 7 slides from one end of the slide groove 5 to the other, it can drive the cylindrical cam 4 to rotate 180 degrees, thereby flipping and inverting the storage box 3.
[0033] Inverting storage box 3 helps the microspheres to remain evenly dispersed in the drug solution, reducing the formation of sediment. This ensures that the drug dosage obtained each time the drug solution is extracted for use is accurate, guaranteeing the consistency of the treatment effect.
[0034] A motor 8 is fixedly mounted on the bracket 1. The motor 8 is directly connected to a toothed gear 9. A first gear 10 that cooperates with the toothed gear 9 is fixedly mounted on the rotating shaft 2. The two ends of the slide groove 5 are connected to swing grooves 11 for sliding rod 7.
[0035] Motor 8 drives the toothed gear 9 to rotate. When the toothed gear 9 meshes with the first gear 10, it can drive the storage box 3 to rotate through the rotating shaft 2. When the toothed gear 9 disengages from the first gear 10, the storage box 3 swings back under the action of gravity. The toothed gear 9 continues to rotate, constantly meshing with and disengaging from the first gear 10, causing the storage box 3 to swing continuously. This makes the force on the microspheres in the liquid more uniform and constantly changing, thus keeping the microspheres in a uniformly dispersed state in the bottle.
[0036] The sliding grooves 11 at both ends of the slide 5 allow the slide rod 7 to slide within the sliding grooves 11 when the toothed gear 9 drives the rotating shaft 2 to swing. At this time, the slide rod 7 will not affect the swing of the rotating shaft 2.
[0037] The swing groove 11 is connected to the slide groove 5 through an inclined surface. When the electric push rod 6 drives the slide rod 7 to slide, the inclined surface facilitates the slide rod 7 to slide from the swing groove 11 into the slide groove 5.
[0038] A switch 12 is fixed on the bracket 1 to control the forward and reverse rotation of the electric push rod 6, and a cam 13 that cooperates with the switch 12 is mounted on the bracket 1 for rotation.
[0039] Switch 12 is specifically a push-button spring switch, which typically consists of a push button, a spring, a mounting base, and conductive contacts. The push button is usually made of plastic or metal and has a certain degree of pressing performance and mechanical strength. The spring's function is to allow the button to automatically return to its original position and ensure the elasticity of the press. The mounting base is used to fix the button and spring, ensuring that their positions do not change. The conductive contacts are the key part connecting the circuit; pressing the button connects or disconnects the circuit through the contacts, thus realizing the switch function.
[0040] The switch 12 contains two sets of circuits. When the switch 12 is pressed, the spring 21 is compressed, and the conductive contact 22 inside the switch 12 is connected to the circuit below. The electric push rod 6 is carried by a positive current, and at this time the electric push rod 6 extends outward. When the switch 12 is released, the contact inside the switch 12 is reset under the action of the spring 21, and the conductive contact 22 is connected to the circuit above. At this time, the electric push rod 6 is carried by a reverse current, and the electric push rod 6 begins to retract.
[0041] When cam 13 rotates, the protrusion of cam 13 contacts switch 12, which presses switch 12. After the protrusion of cam 13 disengages from switch 12, switch 12 will reset under the action of spring 21.
[0042] A drive shaft 14 is rotatably connected to the bracket 1, and a cam 13 is fixedly sleeved on the drive shaft 14; a second gear 15 is also fixedly sleeved on the drive shaft 14, and the second gear 15 cooperates with the tooth-missing gear 9.
[0043] The missing tooth gear 9 drives the second gear 15 to rotate, and the second gear 15 further drives the cam 13 to rotate, so that the cam 13 alternately presses the switch 12 and disengages the switch 12, thus realizing the alternating extension or retraction of the electric push rod 6.
[0044] Because the missing tooth gear 9 has fewer teeth, it needs to rotate a certain number of times to drive the second gear 15 to rotate once. Therefore, the cam 13, which is coaxial with the second gear 15, needs a longer time to rotate once, which means it needs a longer time to press the switch 12 once. This reduces the frequency of the electric push rod 6 extending or retracting, allowing the storage box 3 to rotate at a suitable frequency.
[0045] The drive shaft 14 is fixed to the bracket 1 by a one-way bearing.
[0046] The one-way bearing ensures that the drive shaft 14 can only rotate in one direction, preventing the drive shaft 14 from reversing due to the spring force of the spring 21, gravity, or vibration.
[0047] The storage box 3 has several storage slots, and the storage slots are slidably connected to the clamping plate 16. The clamping plate 16 is fixed to the storage box 3 by a compression spring 17.
[0048] After the microspheres are placed inside the bottle and the bottle is placed in the storage tank, the compression spring 17 pushes the clamping plate 16 closer to the bottle, thereby clamping the bottle.
[0049] Storage box 3 is detachably connected to a lid 18.
[0050] The lid 18 has a through hole, and the storage box 3 has a threaded hole. The lid 18 is connected to the storage box 3 by bolts.
[0051] After the bottle is placed into the storage box 3, the lid 18 is screwed onto the storage box 3 with bolts. This prevents the bottle from falling out of the storage box when the storage box 3 is flipped or swung.
[0052] The top of the clamp 16 extends outward to form a guide section.
[0053] When the bottle is placed into the storage tank, the bottle first contacts the guide part, which drives the clamping plate 16 to move. At this time, the compression spring 17 is compressed and continues to press down to the bottom of the storage tank. The compression spring 17 continuously applies elastic force to the bottle through the clamping plate 16 to prevent the bottle from sliding out.
[0054] A counterweight 19 is slidably connected to the side of storage box 3.
[0055] When the storage box 3 is flipped, the counterweight 19 slides down, keeping the center of the storage box 3 at the bottom, which helps the storage box 3 to remain stable when it swings.
[0056] The storage box 3 is equipped with an insulation layer 20.
[0057] The insulation layer 20 can maintain the temperature inside the storage box 3, which is beneficial for storage.
[0058] Specific work process:
[0059] S1: Rotate the bolts on the box cover 18, remove the box cover 18, put the bottle containing the microspheres into the storage box 3, the bottle squeezes the clamping plate 16, the compression spring 17 is compressed and stored, after the bottle is lowered to the bottom, the compression spring 17 pushes the clamping plate 16 closer to the bottle, thereby clamping the bottle. After several bottles are placed, put the box cover 18 back on the storage box 3, and then tighten the bolts.
[0060] S2: Start the power supply, the motor 8 starts to rotate, driving the toothed gear 9 to rotate continuously. The toothed gear 9 meshes with the first gear 10, driving the first gear 10 and the storage box 3 to rotate a certain angle and then disengage. After disengagement, the storage box swings back under the action of gravity. The toothed gear 9 and the first gear 10 repeatedly mesh and disengage, realizing the reciprocating swing of the storage box 3, so that the force on the microspheres in the liquid is more uniform and constantly changing, thus maintaining a uniformly dispersed state in the bottle.
[0061] S3: As the toothed gear 9 rotates continuously, it also drives the second gear 15 to rotate intermittently. The second gear 15 further drives the cam 13 to rotate intermittently. After the protruding part of the cam 13 contacts the switch 12, the spring 21 is compressed. The conductive contact 22 inside the switch 12 is connected to the circuit below. The electric push rod 6 is carried by a positive current. At this time, the electric push rod 6 extends outward. The slide rod 7 at the front end of the electric push rod 6 drives the cylindrical cam to rotate 180 degrees forward. The cylindrical cam drives the storage box 3 to rotate 180 degrees forward through the rotating shaft 2, thus achieving inversion.
[0062] S4: After the cam 13 protrusion disengages from the switch 12, the contacts inside the switch 12 are reset under the action of the spring 21, and the conductive contact 22 is connected to the circuit above. At this time, the electric push rod 6 is subjected to reverse current, and the electric push rod 6 begins to retract. The slide rod 7 at the front end of the electric push rod 6 drives the cylindrical cam to rotate 180 degrees in reverse. The cylindrical cam drives the storage box 3 to rotate 180 degrees in reverse through the rotating shaft 2, thus achieving inversion again.
[0063] Although embodiments of the present invention have been shown and described, those skilled in the art will understand that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the present invention, the scope of which is defined by the claims and their equivalents.
Claims
1. A polymeric microsphere storage device comprising a holder (1), characterised in that, The support (1) is rotatably connected with a rotating shaft (2), the rotating shaft (2) is fixedly connected with a storage box (3), the rotating shaft (2) is fixedly connected with a cylindrical cam (4), the cylindrical cam (4) is provided with a sliding groove (5), the support (1) is provided with an electric push rod (6), the electric push rod (6) is connected with a sliding rod (7) at the end, and the sliding rod (7) is slidably arranged in the sliding groove (5).
2. The polymeric microsphere storage device of claim 1, wherein, The support (1) is provided with a motor (8), the motor (8) is directly connected with a toothless gear (9), the rotating shaft (2) is fixedly sleeved with a first gear (10) matched with the toothless gear (9), and the sliding groove (5) is communicated with an oscillating groove (11) for sliding of the sliding rod (7) at both ends.
3. A polymeric microsphere storage device according to claim 2, wherein, The support (1) is fixedly provided with a switch (12) for controlling forward and reverse rotation of the electric push rod (6), and the support (1) is rotatably provided with a cam (13) matched with the switch (12).
4. The polymeric microsphere storage device of claim 3, wherein, The support (1) is rotatably connected with a transmission shaft (14), and the cam (13) is fixedly sleeved on the transmission shaft (14); the transmission shaft (14) is also fixedly sleeved with a second gear (15), and the second gear (15) is matched with the toothless gear (9).
5. A polymeric microsphere storage device according to claim 4, wherein, The transmission shaft (14) and the support (1) are fixed through a one-way bearing.
6. The polymeric microsphere storage device of claim 1, wherein, A plurality of storage grooves are formed in the storage box (3), a clamping plate (16) is slidably connected in the storage groove, and the clamping plate (16) and the storage box (3) are fixed through a compression spring (17).
7. A polymeric microsphere storage device according to claim 6, wherein, The storage box (3) is detachably connected with a box cover (18).
8. The polymeric microsphere storage device of claim 6, wherein, The top of the clamping plate (16) extends outward to form a guide portion.
9. The polymeric microsphere storage device of claim 1, wherein, A counterweight (19) is slidably connected to the side of the storage box (3).
10. The polymeric microsphere storage device of claim 1, wherein, A heat preservation layer (20) is arranged in the storage box (3).
Citation Information
Patent Citations
Microsphere storage device for in-vitro diagnosis
CN222117667U