Liquid storage bag

Abstract

The utility model relates to the technical field of cell culture devices, and provides a liquid storage bag which comprises a bag body, a liquid outlet pipe is arranged at an outlet of the bag body, a liquid inlet pipe is arranged at a first inlet of the bag body, and liquid stopping clamps are arranged on the liquid outlet pipe and the liquid inlet pipe. One end of the gas pipeline is connected with the second inlet of the bag body, and the other end of the gas pipeline is connected with an external gas source; and a liquid stopping clamp is arranged on the gas pipeline. According to the liquid storage bag provided by the utility model, the bag body is provided with the gas pipeline and the liquid stopping clip. During liquid adding, the liquid stopping clamp of the liquid inlet pipe is opened, the liquid stopping clamps of the liquid outlet pipe and the gas pipeline are closed, and liquid is added into the bag through the liquid inlet pipe; when liquid is discharged, the liquid stopping clamp of the liquid outlet pipe is opened, the liquid stopping clamps of the liquid inlet pipe and the gas pipeline are firstly closed, and the liquid in the bag body is guided out; in the later period of liquid discharging, the liquid stopping clamp of the gas pipeline is opened, the bag body is inflated, the pressure intensity inside and outside the bag body is balanced, the liquid can flow out rapidly, and waste is avoided.

Description

Technical Field

[0001] This utility model relates to the field of cell culture device technology, specifically to a liquid storage bag. Background Technology

[0002] Disposable 2D storage bags typically utilize multi-layer co-extruded film materials to ensure extremely low gas permeability, good physical strength, chemical compatibility, and biocompatibility. The bags offer high transparency, facilitating observation of the liquid's state and aiding in process assessment. They are usually sterilized by gamma irradiation and vacuum-packed in double-layer PE bags to ensure sterility and low endotoxin levels, making them crucial consumables for liquid storage and transport in the biopharmaceutical industry. Compared to traditional stainless steel containers, these bags are lightweight, flexible, and cost-effective, compatible with various mainstream transport tools on the market, easy to operate, and improve work efficiency. They are primarily used for the storage and transport of buffer solutions and culture media, bioreactor feeding and harvesting, intermediate product collection and storage, pre-chromatographic solution storage, bulk solution storage and transport, product sampling and retention, finished product storage, and formulation filling. They are particularly suitable for small-scale applications in cell therapy, antibody drug seed amplification, and vaccine development and clinical manufacturing stages.

[0003] Commercially available liquid storage bags typically consist of a bag body and two tubing lines: an inlet pipe with a stop clamp and an outlet pipe. To add liquid, the stop clamp on the inlet pipe is opened, and the stop clamp on the outlet pipe is closed, allowing liquid to be added through the inlet pipe. To dispensing, the stop clamp on the outlet pipe is opened, and the stop clamp on the inlet pipe is closed, allowing the liquid to be drained from the bag. However, towards the end of the dispensing process, due to pressure, the flow rate becomes very slow, and some liquid may not even drain completely, resulting in waste. Utility Model Content

[0004] Therefore, the technical problem to be solved by this utility model is that in the later stage of liquid discharge from the existing liquid storage bag, the flow rate becomes very slow due to the pressure, and some of the liquid in the bag cannot be discharged, resulting in waste. Therefore, this utility model provides a liquid storage bag.

[0005] To solve the above-mentioned technical problems, the technical solution of this utility model is as follows:

[0006] This utility model provides a liquid storage bag, including a bag body, an outlet pipe at the outlet of the bag body, and an inlet pipe at the first inlet of the bag body. Both the outlet pipe and the inlet pipe are equipped with liquid-stopping clamps. It also includes a gas pipeline, one end of which is connected to the second inlet of the bag body, and the other end of which is connected to an external gas source. A liquid-stopping clamp is provided on the gas pipeline. During the later stages of liquid outflow, the liquid-stopping clamp on the gas pipeline is opened, and air is injected into the bag body to accelerate the outflow of liquid from the bag body.

[0007] Furthermore, the gas pipeline is equipped with a filter for filtering the gas.

[0008] Furthermore, the first inlet and the second inlet are the same inlet, and both the gas pipeline and the liquid inlet are connected to the first inlet.

[0009] Furthermore, it also includes a main pipe; the gas pipeline and the liquid inlet pipe merge and are connected to one end of the main pipe, and the other end of the main pipe is connected to the first inlet.

[0010] Furthermore, a first support member is provided at the first inlet. The first support member includes two parallel and spaced rods, each of which extends along the axial direction of the liquid inlet pipe. The two rods keep the upper and lower inner surfaces of the bag at the first inlet separated.

[0011] Furthermore, a second support is provided at the outlet, the second support comprising two parallel spaced rods, each rod extending along the axial direction of the liquid outlet pipe, the two rods ensuring that the upper and lower inner surfaces of the bag at the outlet are always separated.

[0012] Furthermore, the external air source is a syringe.

[0013] The technical solution of this utility model has the following advantages:

[0014] The liquid storage bag provided by this utility model has a gas pipeline and a liquid stop clamp on the bag body. When adding liquid, open the liquid stop clamp of the liquid inlet pipe and close the liquid stop clamps of the liquid outlet pipe and the gas pipeline, and add liquid into the bag through the liquid inlet pipe; when discharging liquid, open the liquid stop clamp of the liquid outlet pipe and close the liquid stop clamps of the liquid inlet pipe and the gas pipeline first to drain the liquid out of the bag; when the liquid discharge is in the later stage, open the liquid stop clamp of the gas pipeline to inflate the bag into air, balance the pressure inside and outside the bag, and allow the liquid to flow out quickly to avoid waste. Attached Figure Description

[0015] To more clearly illustrate the specific embodiments of this utility model or the technical solutions in the prior art, the drawings used in the description of the specific embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are some embodiments of this utility model. For those skilled in the art, other drawings can be obtained from these drawings without creative effort.

[0016] Figure 1 This is a schematic diagram of the liquid storage bag in an embodiment of the present utility model;

[0017] Figure 2 This is a schematic diagram of the first support member in the liquid storage bag in an embodiment of the present invention.

[0018] Explanation of reference numerals in the attached figures:

[0019] 1. Bag body; 2. Outlet; 3. Liquid outlet pipe; 4. Liquid inlet pipe; 5. Liquid stop clamp; 6. Gas pipeline; 7. First inlet; 8. Filter; 9. First support component; 10. Second support component; 11. Rod body. Detailed Implementation

[0020] The technical solution of this utility model will now be clearly and completely described with reference to the accompanying drawings. Obviously, the described embodiments are only some, not all, of the embodiments of this utility model. Based on the embodiments of this utility model, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of this utility model.

[0021] In the description of this utility model, it should be noted that the terms "center," "upper," "lower," "left," "right," "vertical," "horizontal," "inner," and "outer," etc., indicating the orientation or positional relationship, are based on the orientation or positional relationship shown in the accompanying drawings and are only for the convenience of describing this utility model and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of this utility model. Furthermore, the terms "first," "second," and "third" are used for descriptive purposes only and should not be construed as indicating or implying relative importance.

[0022] In the description of this utility model, it should be noted that, unless otherwise explicitly specified and limited, the terms "installation," "connection," and "joining" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; and they can refer to the internal connection of two components. Those skilled in the art can understand the specific meaning of the above terms in this utility model based on the specific circumstances.

[0023] Furthermore, the technical features involved in the different embodiments of this utility model described below can be combined with each other as long as they do not conflict with each other.

[0024] like Figure 1 As shown, this embodiment provides a liquid storage bag, including a bag body 1, an outlet pipe 3 at the outlet 2 of the bag body 1, an inlet pipe 4 at the first inlet 7 of the bag body 1, and a liquid stop clamp 5 on both the outlet pipe 3 and the inlet pipe 4; it also includes a gas pipeline 6, one end of which is connected to the second inlet of the bag body 1, and the other end of which is connected to an external gas source; the gas pipeline 6 is equipped with a liquid stop clamp 5, and during the later stage of liquid outflow, the liquid stop clamp 5 on the gas pipeline 6 is opened and air is injected into the bag body 1 to accelerate the outflow of liquid in the bag body 1.

[0025] The liquid storage bag provided in this embodiment has a gas pipeline 6 and a liquid stop clamp 5 on the bag body 1. When adding liquid, open the liquid stop clamp 5 of the liquid inlet pipe 4 and close the liquid stop clamps 5 of the liquid outlet pipe 3 and the gas pipeline 6, and add liquid into the bag through the liquid inlet pipe 4; when discharging liquid, open the liquid stop clamp 5 of the liquid outlet pipe 3 and first close the liquid stop clamps 5 of the liquid inlet pipe 4 and the gas pipeline 6 to discharge the liquid in the bag body 1; when the liquid discharge is in the later stage, open the liquid stop clamp 5 of the gas pipeline 6 again to inflate the bag body 1 with air, balance the pressure inside and outside the bag body 1, so that the liquid can flow out quickly and avoid waste.

[0026] The gas pipeline 6 is equipped with a filter 8 for filtering gas to prevent external gas sources from entering the bag 1 and contaminating the internal liquid.

[0027] The first inlet 7 and the second inlet can be different inlets, or they can be the same inlet. When they are the same inlet, both the gas pipeline 6 and the liquid inlet pipe 4 are connected to the first inlet 7.

[0028] It also includes a main pipe; the gas pipeline 6 and the liquid inlet pipe 4 merge and are connected to one end of the main pipe, and the other end of the main pipe is connected to the first inlet 7.

[0029] like Figure 1 , Figure 2 As shown, a first support member 9 is provided at the first inlet 7. The first support member 9 includes two parallel and spaced rods 11. Each rod 11 extends along the axial direction of the liquid inlet pipe 4. For example, the rod 11 can be a semi-cylindrical rod 11. The planar sides of the two semi-cylindrical rods 11 can be arranged facing each other. When the liquid in the bag 1 decreases, the upper and lower inner surfaces of the bag 1 will approach each other. When the upper and lower inner surfaces of the bag 1 come into contact with the rods 11, they will no longer approach each other. At this time, under the support of the two rods 11, the upper and lower inner surfaces of the bag 1 at the first inlet 7 are always separated, ensuring that the liquid can pass smoothly through the first inlet 7.

[0030] The outlet 2 is provided with a second support member 10, which includes two parallel and spaced rods 11. Each rod 11 extends along the axial direction of the liquid outlet pipe 3. For example, the rod 11 can be a semi-cylindrical rod 11. The planar sides of the two semi-cylindrical rods 11 can be arranged facing each other. When the liquid in the bag 1 decreases, the upper and lower inner surfaces of the bag 1 will approach each other. When the upper and lower inner surfaces of the bag 1 come into contact with the rods 11, they will no longer approach each other. At this time, under the support of the two rods 11, the upper and lower inner surfaces of the bag 1 at the outlet 2 are always separated, ensuring that the liquid can pass smoothly through the outlet 2.

[0031] The external gas source can be a syringe. In the later stage of liquid dispensing, the syringe is connected to the end of the gas line 6 away from the bag body 1, and gas is injected into the bag body 1 through the syringe.

[0032] Obviously, the above embodiments are merely illustrative examples for clear explanation and are not intended to limit the implementation. Those skilled in the art will recognize that other variations or modifications can be made based on the above description. It is neither necessary nor possible to exhaustively list all possible implementations here. However, obvious variations or modifications derived therefrom are still within the protection scope of this invention.

Claims

1. A liquid storage bag comprising a bag body (1), an outlet liquid tube (3) arranged at an outlet (2) of the bag body (1), an inlet liquid tube (4) arranged at a first inlet (7) of the bag body (1), and a liquid stopper (5) arranged on each of the outlet liquid tube (3) and the inlet liquid tube (4); characterized in that, Also comprising: a gas pipeline (6) connected to the second inlet of the bag (1) at one end and to an external gas source at the other end; a liquid stopper (5) is arranged on the gas pipeline (6), and the liquid stopper (5) is opened to inflate the bag (1) to accelerate the liquid flow out of the bag (1) in the late stage of liquid discharge.

2. The liquid storage bag according to claim 1, wherein a filter (8) for filtering gas is arranged on the gas pipeline (6).

3. The liquid storage bag according to claim 1, wherein the first inlet (7) and the second inlet are the same inlet, and the gas pipeline (6) and the liquid inlet pipeline (4) are both connected to the first inlet (7).

4. The liquid storage bag according to claim 3, wherein a main pipeline is further included; the gas pipeline (6) and the liquid inlet pipeline (4) are connected to one end of the main pipeline in parallel, and the other end of the main pipeline is connected to the first inlet (7).

5. The liquid storage bag according to claim 1, wherein a first opening member (9) is arranged at the first inlet (7), and the first opening member (9) includes two parallel and spaced rod bodies (11), each of which extends along the axial direction of the liquid inlet pipeline (4), and the two rod bodies (11) keep the upper and lower inner surfaces of the bag (1) at the first inlet (7) separated.

6. The liquid storage bag according to claim 1, wherein a second opening member (10) is arranged at the outlet (2), and the second opening member (10) includes two parallel and spaced rod bodies (11), each of which extends along the axial direction of the liquid outlet pipeline (3), and the two rod bodies (11) keep the upper and lower inner surfaces of the bag (1) at the outlet (2) separated.

7. The liquid storage bag according to claim 1, wherein the external gas source is a syringe.

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