Full-automatic immunohistochemical dyeing machine

Abstract

The utility model discloses a full-automatic immunohistochemical dyeing machine, which relates to the technical field of immunohistochemical dyeing machines, and comprises a box body, four support rods are arranged on the inner bottom side of the box body, the outer surfaces of the four support rods are connected with a fixed frame, two kits are arranged on the upper surface of the fixed frame, and the upper surface of the fixed frame is connected with a rotating shaft. According to the dyeing machine, through the cooperation of the fixing frame, the partition plate, the mounting groove, the mounting block, the adjusting block and the multiple sets of fixing pins, a kit and the fixing frame can be conveniently and rapidly disassembled and assembled, regular cleaning and maintenance of the kit and the fixing frame are facilitated, the cleanliness of the dyeing environment is guaranteed, and samples are prevented from being polluted and damaged; and through the cooperation of the reagent rack, the adjusting bottom plate, the adjusting handle, the movable rod, the positioning column and the limiting frame, the distance between the adjusting bottom plate and the reagent rack can be conveniently and flexibly adjusted, so that the limiting and fixing size of the kit body can be conveniently adjusted according to the model size of a reagent tube, the adaptability of the kit in use is improved, and the use cost is reduced.

Description

Technical Field

[0001] This utility model relates to the field of immunohistochemical staining machines, and in particular to a fully automated immunohistochemical staining machine. Background Technology

[0002] Immunohistochemical staining is an important tool in pathological examination. Immunohistochemical staining requires an immunohistochemical staining machine. For example, a Chinese patent discloses a fully automated immunohistochemical staining machine with constant temperature and humidity functions (publication number CN221860075U). Although this machine can heat-repair immunohistochemical slides, different types of reagent tubes are used during staining. Due to these differences in size and type, incompatibility issues arise when placing the tubes into the machine, affecting the suitability of the staining process, increasing costs, and reducing efficiency. Utility Model Content

[0003] To address the shortcomings of existing technologies, this invention provides a fully automated immunohistochemical staining machine, which solves the problems mentioned in the background section.

[0004] To achieve the above objectives, this utility model is implemented through the following technical solution: a fully automatic immunohistochemical staining machine, including a box, four support rods are provided on the inner bottom side of the box, a fixing frame is connected to the outer surface of the four support rods, and two reagent kits are provided on the upper surface of the fixing frame;

[0005] The reagent kit includes a box body, two mounting blocks on one side of the box body, a reagent rack on the inner wall of the box body, multiple reagent slots on the surface of the reagent rack, and four connecting rods that are connected through the surface of the reagent rack. The bottom ends of the four connecting rods are connected to an adjusting base plate.

[0006] As a further technical solution of this utility model, an electric lifting rod is provided on the inner bottom side of the box body. The top end of the electric lifting rod is connected to the bottom surface of the fixed frame. A partition is connected to the upper surface of the fixed frame. Mounting grooves are opened on both sides of the partition at the corresponding positions of the sliding path of the mounting block. Two movable grooves are opened on the top surface of the partition.

[0007] As a further technical solution of this utility model, an adjustment handle is connected to the outer surface of the top of both connecting rods, a slide rod is provided on one side of the adjustment handle, a movable rod is connected to the outer surface of the slide rod, a limit frame is provided on both sides of the box, and a second spring is connected to the outer surface of the slide rod and on one side of the movable rod.

[0008] As a further technical solution of this utility model, a guide block is connected to one side of the bottom of the movable rod, and a positioning post is connected to the other side. A guide groove is opened at the corresponding position of the sliding path of the guide block on the inner side wall of the limiting frame, and multiple positioning holes are opened at the corresponding positions of the positioning post on the inner side wall of the limiting frame.

[0009] As a further technical solution of this utility model, the inner sidewalls of the two movable slots are provided with guide posts, the outer surface of the guide posts is connected with adjustment blocks, one side of the adjustment blocks is provided with multiple sets of fixing pins, the outer surface of the guide posts and the side of the adjustment blocks are connected with a first spring, and one side of the mounting block is provided with a matching insertion hole corresponding to the fixing pin.

[0010] As a further technical solution of this utility model, the inner diameter of the box body is adapted to the sliding path of the adjusting base plate, the outer diameter of the slide rod is adapted to the sliding path of the movable rod, the inner diameter of the guide groove is adapted to the sliding path of the guide block, and the inner diameter of the positioning hole is adapted to the outer diameter of the positioning post.

[0011] As a further technical solution of this utility model, the outer diameter of the support rod is adapted to the sliding path of the fixed frame, the inner diameter of the mounting groove is adapted to the sliding path of the mounting block, the inner diameter of the movable groove is adapted to the sliding path of the adjusting block, and the box body is connected to the fixed frame through the mounting block and the partition.

[0012] This invention provides a fully automated immunohistochemical staining machine, which has the following advantages compared with the prior art:

[0013] 1. This design is a fully automated immunohistochemical staining machine. Through the cooperation between the fixed frame, partition, mounting slot, mounting block, adjustment block, and multiple sets of fixing pins, it is possible to facilitate the quick assembly and disassembly of the reagent kit and the fixed frame. This facilitates the regular cleaning and maintenance of the reagent kit and the fixed frame, ensures a clean staining environment, and prevents the samples from being contaminated or damaged.

[0014] 2. This fully automated immunohistochemical staining machine, through the cooperation between the reagent rack, the adjusting base plate, the adjusting handle, the movable rod, the positioning column, and the limiting frame, can conveniently and flexibly adjust the distance between the adjusting base plate and the reagent rack. This allows for easy adjustment of the limiting and fixing dimensions of the box according to the model and size of the reagent tubes, improving the adaptability of the reagent kits and reducing the cost of use. Attached Figure Description

[0015] Figure 1 This is a schematic diagram of the structure of a fully automated immunohistochemical staining machine;

[0016] Figure 2 For a fully automated immunohistochemical staining machine Figure 1AA section view in the middle;

[0017] Figure 3 This is a schematic diagram of the exploded structure of a fully automated immunohistochemical staining machine;

[0018] Figure 4 For a fully automated immunohistochemical staining machine Figure 3 Enlarged view of A in the image;

[0019] Figure 5 This is a schematic diagram of the exploded structure of a reagent kit for a fully automated immunohistochemistry staining machine.

[0020] In the diagram: 1. Box body; 11. Electric lifting rod; 2. Support rod; 3. Fixing frame; 31. Partition; 32. Movable slot; 33. Guide post; 34. Adjusting block; 35. Mounting slot; 36. Fixing pin; 37. First spring; 4. Reagent kit; 41. Box body; 42. Reagent rack; 43. Connecting rod; 44. Adjusting base plate; 45. Adjusting handle; 46. Slide rod; 47. Movable rod; 48. Second spring; 49. Reagent slot; 401. Limiting frame; 402. Guide block; 403. Positioning post; 404. Guide slot; 405. Positioning hole; 406. Mounting block. Detailed Implementation

[0021] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments of the present utility model. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. All other embodiments obtained by those skilled in the art based on the embodiments of the present utility model without creative effort are within the protection scope of the present utility model.

[0022] Please see Figure 1-4 This utility model provides a technical solution for a fully automated immunohistochemical staining machine: it includes a housing 1, four support rods 2 are provided on the inner bottom side of the housing 1, a fixing frame 3 is connected to the outer surface of the four support rods 2, two reagent kits 4 are provided on the upper surface of the fixing frame 3, the reagent kit 4 includes a box body 41, two mounting blocks 406 are provided on one side of the box body 41, a reagent rack 42 is provided on the inner side wall of the box body 41, multiple reagent slots 49 are opened on the surface of the reagent rack 42, four connecting rods 43 are connected through the surface of the reagent rack 42, and an adjusting base plate 44 is connected to the bottom end of the four connecting rods 43.

[0023] like Figure 1-4As shown, an electric lifting rod 11 is provided on the inner bottom side of the housing 1. The top of the electric lifting rod 11 is connected to the bottom surface of the fixing frame 3. A partition 31 is connected to the upper surface of the fixing frame 3. Mounting grooves 35 are opened on both sides of the partition 31 at the corresponding positions of the sliding path of the mounting block 406. Two movable grooves 32 are opened on the top surface of the partition 31. Guide posts 33 are provided on the inner side walls of the two movable grooves 32. Adjusting blocks 34 are connected to the outer surface of the guide posts 33. Multiple sets of fixing pins 36 are provided on one side of the adjusting block 34. A first spring 37 is connected to the outer surface of the guide posts 33 and located on one side of the adjusting block 34. One side of 406 has a corresponding insertion hole for the fixing pin 36. The outer diameter of the support rod 2 is adapted to the sliding path of the fixing frame 3. The inner diameter of the mounting groove 35 is adapted to the sliding path of the mounting block 406. The inner diameter of the movable groove 32 is adapted to the sliding path of the adjusting block 34. The box 41 is connected to the fixing frame 3 through the mounting block 406 and the partition 31. It should be noted that the cooperation between the two adjusting blocks 34 and the multiple sets of fixing pins 36 and the mounting block 406 can facilitate the quick disassembly and assembly of the entire box 41, thereby facilitating the cleaning and maintenance of the box 41 and ensuring the cleanliness of the loaded box 41.

[0024] like Figure 3-5 As shown, adjusting handles 45 are connected to the outer surfaces of the tops of the two connecting rods 43. A sliding rod 46 is provided on one side of the adjusting handle 45, and a movable rod 47 is connected to the outer surface of the sliding rod 46. Limit frames 401 are provided on both sides of the box body 41. A second spring 48 is connected to the outer surface of the sliding rod 46 and to one side of the movable rod 47. A guide block 402 is connected to one side of the bottom of the movable rod 47, and a positioning post 403 is connected to the other side. A guide groove 404 is provided on the inner wall of the limit frame 401 at the corresponding position of the sliding path of the guide block 402. Multiple positioning holes 4 are provided on the inner wall of the limit frame 401 and the positioning post 403 respectively. 05. The inner diameter of the box 41 is adapted to the sliding path of the adjusting base plate 44, the outer diameter of the slide rod 46 is adapted to the sliding path of the movable rod 47, the inner diameter of the guide groove 404 is adapted to the sliding path of the guide block 402, and the inner diameter of the positioning hole 405 is adapted to the outer diameter of the positioning post 403. It should be noted that the adjusting handle 45 and the movable rod 47 can be positioned on the inner side wall of the limiting frame 401, so as to facilitate the adjustment of the distance between the adjusting base plate 44 and the reagent rack 42, thereby facilitating the adjustment of the limiting fixing size according to the length of the reagent tube, and thus facilitating the fixing and use of reagent tubes of various sizes.

[0025] The working principle of this utility model is as follows: two adjusting blocks 34 slide along the inner wall of the movable groove 32, so that the adjusting blocks 34 press the first spring 37 along the outer surface of the guide post 33, and multiple sets of fixing pins 36 separate from one side of the mounting block 406 and retract into the movable groove 32. Then, the box body 41 is lifted up, so that the mounting block 406 separates from the mounting groove 35, and the box body 41 can be disassembled for cleaning.

[0026] According to the size of the reagent tube, hold the two adjusting handles 45 and slide the two movable rods 47 along the outer surface of the slide rod 46 to stretch the second spring 48, causing the positioning post 403 to separate from the positioning hole 405. Then pull the adjusting handles 45 upward to drive the guide block 402 to slide along the inner wall of the guide groove 404, adjust the distance between the adjusting base plate 44 and the reagent rack 42. After adjusting to the appropriate distance, release the movable rods 47. The second spring 48 will drive the movable rods 47 and the positioning post 403 to reset and insert them into the corresponding positioning hole 405 to complete the adjustment of the limit size.

[0027] The above are merely preferred embodiments of this utility model. It should be noted that those skilled in the art can make various improvements and modifications without departing from the principles of this utility model, and these improvements and modifications should also be considered within the scope of protection of this utility model. Structures, devices, and operating methods not specifically described or explained in this utility model are implemented according to conventional methods in the art, unless otherwise specified or limited.

Claims

1. A fully automated immunohistochemical stainer, characterized by, Including the box (1): the inner bottom side of the box (1) is provided with four support rods (2), the outer surface of four support rods (2) is connected with the fixed frame (3), the upper surface of the fixed frame (3) is provided with two reagent boxes (4); The reagent box (4) includes a box body (41), one side of the box body (41) is provided with two mounting blocks (406), the inner side wall of the box body (41) is provided with a reagent rack (42), a plurality of reagent grooves (49) are formed in the surface of the reagent rack (42), four connecting rods (43) are connected to the surface of the reagent rack (42), and the bottom end of the four connecting rods (43) is connected with an adjusting bottom plate (44).

2. The fully automatic immunohistochemical stainer according to claim 1, characterized in that, The inner bottom side of the box (1) is provided with an electric lifting rod (11), the top end of the electric lifting rod (11) is connected to the bottom surface of the fixed frame (3), the upper surface of the fixed frame (3) is connected with a partition plate (31), the both side surfaces of the partition plate (31) are provided with mounting grooves (35) at the corresponding positions of the sliding path of the mounting block (406), and the top surface of the partition plate (31) is provided with two movable grooves (32).

3. The fully automated immunohistochemical stainer of claim 1, wherein, The outer surface of the top of the two connecting rods (43) is connected with an adjusting handle (45), one side of the adjusting handle (45) is provided with a sliding rod (46), the outer surface of the sliding rod (46) is connected with a movable rod (47), the both side surfaces of the box body (41) are provided with a limiting frame (401), and the outer surface of the sliding rod (46) and one side of the movable rod (47) are connected with a second spring (48).

4. The fully automated immunohistochemical stainer of claim 3, wherein, The side of the bottom of the movable rod (47) is connected with a guide block (402), the other side is connected with a positioning column (403), the inner side wall of the limiting frame (401) is provided with a guide groove (404) at the corresponding position of the sliding path of the guide block (402), and the inner side wall of the limiting frame (401) is provided with a plurality of positioning holes (405) corresponding to the positioning column (403).

5. The fully automated immunohistochemical stainer of claim 2, wherein, The inner side wall of the two movable grooves (32) is provided with a guide column (33), the outer surface of the guide column (33) is connected with an adjusting block (34), one side of the adjusting block (34) is provided with a plurality of fixed pins (36), the outer surface of the guide column (33) and one side of the adjusting block (34) are connected with a first spring (37), and one side of the mounting block (406) is provided with a matching jack hole corresponding to the fixed pin (36).

6. The fully automated immunohistochemical stainer of claim 4, wherein, The inner diameter size of the box body (41) is matched with the sliding path of the adjusting bottom plate (44), the outer diameter size of the sliding rod (46) is matched with the sliding path of the movable rod (47), the inner diameter size of the guide groove (404) is matched with the sliding path of the guide block (402), and the inner diameter size of the positioning hole (405) is matched with the outer diameter size of the positioning column (403).

7. The fully automated immunohistochemical stainer of claim 5, wherein, The outer diameter of the support rod (2) is matched with the sliding path of the fixing frame (3), the inner diameter of the mounting groove (35) is matched with the sliding path of the mounting block (406), the inner diameter of the movable groove (32) is matched with the sliding path of the adjusting block (34), and the box body (41) is connected with the fixing frame (3) through the mounting block (406) and the partition plate (31).

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