Rapid extraction device for nucleic acid

Abstract

The utility model relates to the technical field of road paving, and aims to provide a rapid extraction device for nucleic acid, which comprises a shell, a driving component arranged on the shell, a guide component arranged on the driving component, an extraction component arranged below the shell, and a threaded rod structure driven by a reversible motor, linear movement of the lead screw nut pair is achieved through threaded connection, so that the sealing block is driven to move up and down, and the linearity and stability of the sealing block in the moving process are ensured by arranging the guide through hole and the guide rod. Through the design of a guide limiting plate, the moving range of the sealing block is further limited, accidental falling or damage is prevented, and the liquid pumping pipe and the capacitive liquid level sensor are symmetrically arranged. The liquid extraction pipe is used for extracting and discharging a sample solution, and the capacitive liquid level sensor can monitor the liquid level change in the device in real time, so that the accurate control of the extraction process is ensured.

Description

Technical Field

[0001] This utility model relates to the field of nucleic acid extraction technology, and in particular to a rapid nucleic acid extraction device. Background Technology

[0002] In the fields of biomedical research and clinical diagnostics, nucleic acid extraction is a crucial step that directly affects the accuracy and reliability of subsequent analytical results. Traditional nucleic acid extraction methods typically involve tedious manual operations, such as sample grinding, centrifugation, and solution transfer. These operations are not only time-consuming and labor-intensive but also susceptible to contamination, affecting extraction efficiency and purity.

[0003] With advancements in technology, automated and semi-automated nucleic acid extraction devices have emerged, aiming to simplify procedures and improve extraction efficiency and purity. However, existing nucleic acid extraction devices on the market still present some challenges. For example, while some devices achieve automated operation, they are structurally complex, have high maintenance costs, and are not suitable for all types of samples. Furthermore, some devices lack precise liquid level control during extraction, which can easily lead to sample loss or contamination. Utility Model Content

[0004] The purpose of this invention is to provide a rapid nucleic acid extraction device to solve the problems mentioned in the background art and facilitate its widespread application.

[0005] A rapid nucleic acid extraction device includes a housing, a driving assembly on the housing, a guiding assembly on the driving assembly, and an extraction assembly below the housing.

[0006] The drive assembly includes a drive motor fixedly mounted on the housing, a drive threaded rod fixedly mounted on the output end of the drive motor, one end of the drive threaded rod away from the output end of the drive motor being rotatably mounted at the bottom of the housing, a lead screw and nut pair threadedly connected to the drive threaded rod, and a sealing block fixedly mounted on the outer wall of the lead screw and nut pair.

[0007] Furthermore, the guide assembly includes a guide through hole one and a guide through hole two opened on the upper end face of the housing, and guide rods are symmetrically arranged on the sealing block. The end of the guide rod away from the sealing block passes through the guide through hole one and the guide through hole two and is fixedly provided with a guide limiting plate.

[0008] Furthermore, the extraction assembly includes a first extraction tube and a second extraction tube symmetrically arranged below the housing, and a liquid level sensor is fixedly installed on the inner wall of the housing.

[0009] Furthermore, the liquid level sensor is a capacitive liquid level sensor.

[0010] Furthermore, the drive motor is a reversible motor.

[0011] Furthermore, the outer shell of the housing is transparent, and the outer surface of the housing is provided with graduations.

[0012] Furthermore, handles are symmetrically provided on the outer wall of the housing.

[0013] As an improvement, the beneficial effects of this utility model are as follows:

[0014] This invention discloses a rapid nucleic acid extraction device. It utilizes a reversible motor-driven threaded rod structure, with a threaded connection enabling linear movement of the lead screw and nut pair, thereby driving the sealing block to move up and down. This design not only simplifies the transmission structure and reduces maintenance costs but also improves the stability and accuracy of the movement. The guide holes and guide rods ensure the linearity and stability of the sealing block during movement. The guide limiting plate further restricts the movement range of the sealing block, preventing accidental detachment or damage. Symmetrically arranged suction tubes and capacitive liquid level sensors are used. The suction tubes are used for the extraction and discharge of sample solution, while the capacitive liquid level sensors monitor the liquid level changes inside the device in real time, ensuring precise control of the extraction process. Attached Figure Description

[0015] Figure 1 This is an isometric A-view of a rapid nucleic acid extraction device according to the present invention;

[0016] Figure 2 This is an isometric B-view of a rapid nucleic acid extraction device according to the present invention.

[0017] Figure 3 This is an isometric C-view of a rapid nucleic acid extraction device according to the present invention.

[0018] Figure 4 This utility model Figure 1 Enlarged view of point A in the image;

[0019] Figure 5 This utility model Figure 1 Enlarged view of point B in the image;

[0020] Figure 6 This utility model Figure 3 Enlarged view of point C in the image;

[0021] Reference table for attached figures:

[0022] 1. Housing; 2. Drive assembly; 201. Drive motor; 202. Drive threaded rod; 203. Lead screw and nut pair; 204. Sealing block; 3. Guide assembly; 301. Guide through hole one; 302. Guide through hole two; 303. Guide rod; 304. Guide limiting plate; 4. Extraction assembly; 401. Extraction tube one; 402. Extraction tube two; 403. Liquid level sensor; 5. Handle. Detailed Implementation

[0023] The specific embodiments of this utility model will be further described below with reference to the accompanying drawings. Identical components are indicated by the same reference numerals. It should be noted that the terms "front," "rear," "left," "right," "up," and "down" used in the following description refer to directions in the accompanying drawings, while the terms "inner" and "outer" refer to directions toward or away from the geometric center of a specific component, respectively.

[0024] To make the content of this utility model easier to understand, the technical solutions of this utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Identical components are indicated by the same reference numerals.

[0025] This embodiment provides a rapid nucleic acid extraction device, mainly composed of a shell 1, a drive assembly 2, a guide assembly 3, an extraction assembly 4, and additional scales and handles. The shell 1 serves as the main support structure of the entire device, and its outer shell is made of transparent material, allowing users to visually observe the internal operating status. The outer surface of the shell 1 is also equipped with scales for precise control of the liquid volume during operation. Furthermore, handles 5 are symmetrically arranged on the outer wall of the shell 1 for easy handling and carrying.

[0026] In this embodiment, the drive assembly 2 is fixedly disposed above the housing 1. Specifically, the drive assembly 2 includes a drive motor 201, which is fixedly mounted on the upper surface of the housing 1, and a drive threaded rod 202 is fixedly connected to its output end. The end of the drive threaded rod 202 away from the output end of the drive motor 201 is disposed at the bottom of the interior of the housing 1 through a rotatable connection structure such as a bearing, ensuring that the drive threaded rod 202 can rotate smoothly.

[0027] A lead screw and nut assembly 203 is threadedly connected to the drive threaded rod 202. As the drive threaded rod 202 rotates, the lead screw and nut assembly 203 moves linearly along the thread direction. A sealing block 204 is fixedly installed on the outer wall of the lead screw and nut assembly 203. This sealing block 204 is used to ensure a tight seal with the interior of the housing 1 during movement, preventing liquid leakage. It is worth noting that the drive motor 201 is a reversible motor, which means that it can change the direction of rotation as needed, thereby driving the lead screw and nut assembly 203 and the sealing block 204 to reciprocate.

[0028] In this embodiment, to ensure the stability and straightness of the lead screw nut assembly 203 and the sealing block 204 during movement, a guide assembly 3 is also designed. The guide assembly 3 includes two guide through holes 301 and 302 located on the upper surface of the housing 1; their positions may be adjusted according to actual needs. Two guide rods 303 are symmetrically arranged on the upper surface of the sealing block 204. One end of each guide rod 303 is fixedly connected to the sealing block 204, while the other end passes through the guide through holes 301 and 302 respectively, and a guide limiting plate 304 is fixedly provided externally. The guide limiting plate 304 not only restricts the axial movement range of the guide rods 303 but also, through its cooperation with the guide through holes, effectively prevents the sealing block 204 from deflecting or shaking during movement.

[0029] In this embodiment, the extraction component 4 includes two extraction tubes 401 and 402 symmetrically arranged below the housing 1. These two extraction tubes are respectively connected to two different positions inside the device.

[0030] A liquid level sensor 403 is also fixedly installed on the inner wall of the housing 1. This liquid level sensor 403 is preferably a capacitive liquid level sensor. Capacitive liquid level sensors have advantages such as high sensitivity and fast response speed, enabling them to monitor the liquid level changes inside the housing 1 in real time and feed the signal back to the control system. Although the control system is not described in detail in this embodiment, it is essential for achieving automated control and monitoring. Based on the feedback signal from the liquid level sensor, the control system can precisely control the start, stop, and direction of the drive component 2, thereby achieving precise control of the nucleic acid extraction process.

[0031] The above are merely preferred embodiments of this utility model patent and are not intended to limit this utility model patent. Any modifications, equivalent substitutions, and improvements made within the spirit and principles of this utility model patent should be included within the protection scope of this utility model patent.

Claims

1. A device for rapid extraction of nucleic acids comprising a housing (1), characterized in that, The shell (1) is provided with a driving assembly (2) on the upper surface, the driving assembly (2) is provided with a guide assembly (3), the shell (1) is provided with an extraction assembly (4) on the lower surface; The driving assembly (2) comprises a driving motor (201) fixedly arranged on the upper surface of the shell (1), a driving threaded rod (202) is fixedly arranged on the output end of the driving motor (201), one end of the driving threaded rod (202) away from the output end of the driving motor (201) is rotatably arranged in the bottom of the shell (1), a lead screw nut pair (203) is threadedly connected on the driving threaded rod (202), and a sealing block (204) is fixedly arranged on the outer wall of the lead screw nut pair (203).

2. The device for rapid extraction of nucleic acids according to claim 1, characterized in that, The guide assembly (3) comprises a guide through hole one (301) and a guide through hole two (302) formed in the upper end surface of the shell (1), guide rods (303) are symmetrically arranged on the upper surface of the sealing block (204), and guide limiting plates (304) are fixedly arranged on one end of the guide rods (303) away from the sealing block (204) and pass through the guide through hole one (301) and the guide through hole two (302).

3. The device for rapid extraction of nucleic acids according to claim 2, characterized in that, The extraction assembly (4) comprises liquid extraction pipes one (401) and two (402) symmetrically arranged on the lower surface of the shell (1), and a liquid level sensor (403) is fixedly arranged on the inner wall of the shell (1).

4. The device for rapid extraction of nucleic acids according to claim 3, characterized in that, The liquid level sensor (403) is a capacitive liquid level sensor.

5. The device for rapid extraction of nucleic acids according to claim 1, wherein, The driving motor (201) is a reversible motor.

6. The device for rapid extraction of nucleic acids according to claim 5, characterized in that, The shell (1) is transparent, and the outer surface of the shell (1) is provided with a scale.

7. The device for rapid extraction of nucleic acids according to claim 6, characterized in that, Symmetrical handles (5) are arranged on the outer wall of the shell (1).

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