Cooling precipitation device for producing amantadine hydrochloride

Abstract

The utility model discloses a cooling precipitation device for producing amantadine hydrochloride, which belongs to the technical field of cooling precipitation devices, and comprises a precipitation box and a cooling device, an inlet and an outlet of the cooling device are respectively communicated and fixedly provided with a connecting pipe, and the tail ends of the two connecting pipes respectively extend into the precipitation box; a sleeve is fixedly installed at the tail end of the connecting pipe, and a telescopic pipe is sleeved with the sleeve in a sealed and sliding mode. A mounting frame is slidably mounted in the precipitation box, two transverse pipes are symmetrically and fixedly mounted in the mounting frame, a cooling pipe is fixedly mounted between the two transverse pipes in a communicating manner, and the bottoms of the two telescopic pipes are fixedly communicated with the two transverse pipes respectively; two vertical grooves are symmetrically formed in the inner wall of the precipitation box, and electric sliding blocks are slidably mounted between the side wall of the mounting frame and the interiors of the vertical grooves. Compared with the prior art, the cooling effect of the cooling precipitation device for amantadine hydrochloride can be effectively improved, so that the cooling precipitation efficiency of amantadine hydrochloride is further improved.

Description

Technical Field

[0001] This utility model belongs to the technical field of cooling precipitation devices, and in particular, it is a cooling precipitation device for producing adamantane hydrochloride. Background Technology

[0002] Amantadine hydrochloride is a symmetrical tricyclic amine that can inhibit viral penetration into host cells and affect viral uncoating, thereby inhibiting viral replication and playing a role in the treatment and prevention of viral infections. During the production of amantadine hydrochloride, it is necessary to cool it multiple times to facilitate the precipitation process.

[0003] In existing cooling precipitation devices for producing amantadine hydrochloride, the cooling devices mostly involve fixing multiple cooling pipes inside the precipitation chamber to cool the interior. However, the fixed cooling pipes can only provide rapid cooling around the pipes, while other parts of the precipitation chamber require prolonged temperature radiation to cool. This significantly reduces the cooling rate of the cooling precipitation device, thereby reducing precipitation efficiency. Utility Model Content

[0004] The purpose of this invention is to provide a cooling precipitation device for producing adamantane hydrochloride, so as to solve the problems mentioned in the background art.

[0005] To achieve the above objectives, the present invention provides the following technical solution: a cooling precipitation device for producing adamantane hydrochloride, comprising a precipitation box for installing the cooling precipitation device for adamantane hydrochloride and a cooling device for circulating cooling liquid. The cooling device is fixedly installed on the top surface of the precipitation box, and the outlet and inlet of the cooling device are respectively connected and fixedly installed with connecting pipes, and the ends of the two connecting pipes respectively extend into the interior of the precipitation box.

[0006] A sleeve is fixedly installed at one end of the connecting tube that extends into the precipitation tank, and a telescopic tube is sealed and slidably connected inside the sleeve.

[0007] An installation frame is slidably installed inside the precipitation box, and two horizontal pipes are symmetrically fixedly installed inside the installation frame. A cooling pipe is fixedly installed between the two horizontal pipes, and the bottoms of the two telescopic pipes are fixedly connected to the two horizontal pipes respectively.

[0008] Two vertical grooves are symmetrically opened on the inner wall of the precipitation box, and an electric slider is slidably installed between the side wall of the mounting frame and the inside of the vertical groove.

[0009] Preferably, a vertical rod is fixedly installed longitudinally inside the vertical groove, and a sliding hole is longitudinally opened on the top surface of the electric slider.

[0010] Preferably, the vertical rod slides through a sliding hole opened on the side wall of the electric slider.

[0011] Preferably, the sidewall of the electric slider is symmetrically fixed with limiting blocks, and the inner wall of the vertical groove is symmetrically provided with two limiting grooves.

[0012] Preferably, the limiting block fixedly installed on the side wall of the electric slider is slidably connected to the inside of two limiting grooves opened on the inner wall of the vertical groove.

[0013] Preferably, a rubber pad is fixedly bonded to the outer wall of the mounting frame, and the outer wall of the rubber pad slides against the inner wall of the precipitation tank.

[0014] Preferably, the outer walls of the two telescopic tubes are fixedly fitted with sealing rings, and the outer walls of the sealing rings are slidably and sealingly attached to the inner walls of the tubes.

[0015] Compared with the prior art, the technical effects and advantages of this utility model are as follows:

[0016] The cooling precipitation device for producing adamantane hydrochloride benefits from the electric slider between the inner wall of the vertical groove opened between the side wall of the mounting frame and the inner wall of the precipitation box. The electric slider can drive the mounting frame, the horizontal pipe fixedly installed inside the mounting frame, and multiple cooling pipes to move. At this time, adjusting the up and down movement of the electric slider can drive the multiple cooling pipes to move up and down, thereby comprehensively cooling the precipitation box and further improving the cooling effect inside the precipitation box.

[0017] The cooling precipitation device for producing adamantane hydrochloride benefits from the setting of connecting pipes, sleeves and telescopic pipes. When the mounting frame, horizontal pipe and multiple cooling pipes move up and down, the telescopic pipe will slide along the inside of the sleeve. This allows the cooling pipes and horizontal pipes to move up and down while the coolant is constantly circulated in the horizontal pipes and cooling pipes through the sleeve and telescopic pipe.

[0018] The cooling and precipitation device for producing amantadine hydrochloride benefits from the arrangement of a cooling device, connecting pipes, sleeves, and telescopic pipes. The cooling device cools the coolant and introduces it into one of the connecting pipes. Then, through the connecting pipe, the coolant is introduced into the sleeve and telescopic pipe. Subsequently, through the telescopic pipe, it is introduced into the horizontal pipe and cooling pipe. Finally, through the cooling pipe, the coolant is introduced into another telescopic pipe, sleeve, and connecting pipe. This effectively achieves the circulation and cooling of the coolant.

[0019] Compared with existing technologies, the cooling precipitation device for producing adamantane hydrochloride can effectively improve the cooling effect of the cooling precipitation device for adamantane hydrochloride, thereby further improving the cooling precipitation efficiency of adamantane hydrochloride. Attached Figure Description

[0020] To more clearly illustrate the specific embodiments of this utility model or the technical solutions in the prior art, the drawings used in the description of the specific embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are some embodiments of this utility model. For those skilled in the art, other drawings can be obtained from these drawings without creative effort.

[0021] Figure 1 This is a schematic diagram of the structure of this utility model;

[0022] Figure 2 This is a three-dimensional cross-sectional view of the precipitation box in this utility model;

[0023] Figure 3 This is a structural schematic diagram of the telescopic tube, mounting frame, horizontal tube, and cooling tube in this utility model;

[0024] Figure 4 This is a schematic diagram of the connection between the sleeve and the telescopic tube in this utility model.

[0025] Explanation of reference numerals in the attached figures:

[0026] In the diagram: 1. Sedimentation box; 2. Cooling device; 3. Connecting pipe; 4. Sleeve; 5. Telescopic pipe; 6. Mounting frame; 7. Horizontal pipe; 8. Cooling pipe; 9. Electric slider; 10. Vertical rod; 11. Limiting block; 12. Rubber pad; 13. Sealing ring. Detailed Implementation

[0027] In the following description, numerous specific details are set forth in order to provide a more thorough understanding of the present invention. However, it will be apparent to those skilled in the art that the present invention can be practiced without one or more of these details. In other instances, certain technical features well-known in the art have not been described in order to avoid confusion with the present invention.

[0028] Unless otherwise defined, the directions mentioned herein, such as up, down, left, right, front, back, inside, and outside, are based on the directions shown in the figures of this utility model, and are explained here together.

[0029] The connection method can be any existing method, such as bonding, welding, or bolting, depending on the actual needs.

[0030] like Figures 1 to 4The main structure of the cooling precipitation device for producing adamantane hydrochloride is a precipitation box 1 for installing the cooling precipitation device for adamantane hydrochloride and a cooling device 2 for circulating cooling liquid. The cooling device 2 is fixedly installed on the top surface of the precipitation box 1, and the outlet and inlet of the cooling device 2 are respectively connected and fixedly installed with connecting pipes 3, and the ends of the two connecting pipes 3 extend into the interior of the precipitation box 1.

[0031] A sleeve 4 is fixedly installed at one end of the connecting pipe 3 extending into the precipitation tank 1, and a telescopic pipe 5 is slidably connected inside the sleeve 4. Thanks to the setting of the cooling device 2, the connecting pipe 3, the sleeve 4 and the telescopic pipe 5, the coolant can be cooled and introduced into one of the connecting pipes 3 through the cooling device 2. Then, the coolant is introduced into the sleeve 4 and the telescopic pipe 5 through the connecting pipe 3. Then, it is introduced into the horizontal pipe 7 and the cooling pipe 8 through the telescopic pipe 5. Then, the coolant is introduced into the other telescopic pipe 5, the sleeve 4 and the connecting pipe 3 through the cooling pipe 8. In this way, the circulation and cooling of the coolant can be effectively realized.

[0032] An installation frame 6 is slidably installed inside the precipitation box 1, and two horizontal pipes 7 are symmetrically fixedly installed inside the installation frame 6. A cooling pipe 8 is fixedly installed between the two horizontal pipes 7, and the bottoms of two telescopic pipes 5 are fixedly connected to the two horizontal pipes 7 respectively. Multiple cooling pipes 8 are installed between the two horizontal pipes 7, and the two telescopic pipes 5 are connected to the two horizontal pipes 7 respectively. In this way, the coolant can be evenly distributed inside the multiple cooling pipes 8 through the two horizontal pipes 7, thereby improving the circulation effect of the coolant in the cooling pipes 8.

[0033] Two vertical grooves are symmetrically opened on the inner wall of the precipitation box 1. An electric slider 9 is slidably installed between the side wall of the mounting frame 6 and the inside of the vertical groove. Thanks to the electric slider 9 between the side wall of the mounting frame 6 and the inner wall of the vertical groove, the mounting frame 6, the horizontal pipe 7 fixedly installed inside the mounting frame 6, and the multiple cooling pipes 8 can be moved by the electric slider 9. At this time, adjusting the up and down movement of the electric slider 9 can drive the multiple cooling pipes 8 to move up and down, thereby comprehensively cooling the inside of the precipitation box 1 and further improving the cooling effect inside the precipitation box 1.

[0034] A vertical rod 10 is fixedly installed in the vertical groove, and a sliding hole is opened in the top surface of the electric slider 9 in the longitudinal direction. The vertical rod 10 slides through the sliding hole opened on the side wall of the electric slider 9. The vertical rod 10 can effectively limit the sliding direction of the electric slider 9 and the mounting frame 6, and further improve the stability of the mounting frame 6 when sliding.

[0035] Limiting blocks 11 are symmetrically fixedly installed on the side wall of the electric slider 9. Two limiting grooves are symmetrically opened on the inner wall of the vertical groove. The limiting blocks 11 fixedly installed on the side wall of the electric slider 9 are slidably connected to the inside of the two limiting grooves opened on the inner wall of the vertical groove. The limiting blocks 11 can effectively further improve the stability of the electric slider 9 and the mounting frame 6 when sliding.

[0036] A rubber pad 12 is fixedly bonded to the outer wall of the mounting frame 6, and the outer wall of the rubber pad 12 slides against the inner wall of the precipitation tank 1. Thanks to the setting of the rubber pad 12, the friction between the side wall of the mounting frame 6 and the inner wall of the precipitation tank 1 can be effectively reduced, thereby further improving the service life of the mounting frame 6.

[0037] The outer walls of the two telescopic tubes 5 are fixedly fitted with sealing rings 13, and the outer walls of the sealing rings 13 are slidably fitted against the inner walls of the sleeves 4. The sealing rings 13 can further improve the sealing between the outer walls of the telescopic tubes 5 and the inner walls of the sleeves 4.

[0038] Working principle

[0039] The cooling precipitation device for producing amantadine hydrochloride first introduces coolant into the cooling device 2, where it is further cooled before being introduced into one of the connecting pipes 3. Then, through the connecting pipe 3, the coolant is introduced into one of the sleeves 4 and the telescopic pipe 5. The telescopic pipe 5 then introduces the coolant into two horizontal pipes 7 and multiple cooling pipes 8, thereby cooling the precipitation chamber 1. After heat exchange, the coolant is introduced into another telescopic pipe 5 and sleeve 4, and then through another connecting pipe 3, it is reintroduced into the cooling device 2 for cooling and reuse. Simultaneously, two electric sliders 9 are activated, causing the mounting frame 6 and multiple cooling pipes 8 and horizontal pipes 7 to move upwards and downwards. This movement of the cooling pipes 8 within the precipitation chamber 1 accelerates the cooling efficiency, further improving the precipitation effect.

[0040] It should be noted that, in this document, relational terms such as "one" and "two" are used merely to distinguish one entity or operation from another, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Furthermore, the terms "comprising," "including," or any other variations thereof are intended to cover non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements includes not only those elements but also other elements not expressly listed, or elements inherent to such a process, method, article, or apparatus. Without further limitations, the phrase "comprising an element defined as..." does not exclude the presence of other identical elements in the process, method, article, or apparatus that includes said element.

[0041] Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the present invention, the scope of which is defined by the appended claims and their equivalents.

Claims

1. A cooling crystallization apparatus for producing amantadine hydrochloride, comprising a crystallization tank (1) for installing a cooling crystallization apparatus for amantadine hydrochloride and a cooling device (2) for circulating a cooling liquid, characterized in that: The cooling device (2) is fixedly installed on the top surface of the precipitation tank (1), and the water outlet and the water inlet of the cooling device (2) are respectively communicated with the fixedly installed connecting pipes (3), and the ends of the two connecting pipes (3) respectively extend into the interior of the precipitation tank (1); The end of the connecting pipe (3) extending into the precipitation tank (1) is fixedly installed with a sleeve pipe (4), and the sleeve pipe (4) is sealingly sleeved with an expansion pipe (5); The installation frame (6) is slidingly installed in the interior of the precipitation tank (1), and two horizontal pipes (7) are symmetrically fixedly installed in the installation frame (6), a cooling pipe (8) is fixedly installed between the two horizontal pipes (7), and the bottoms of the two expansion pipes (5) are respectively fixedly communicated with the two horizontal pipes (7); Two vertical grooves are symmetrically formed in the inner wall of the precipitation tank (1), and an electric sliding block (9) is slidingly installed between the side wall of the installation frame (6) and the interior of the vertical groove.

2. A cooling crystallization apparatus for the production of amantadine hydrochloride according to claim 1, characterized in that: A vertical rod (10) is longitudinally fixedly installed in the interior of the vertical groove, and a sliding hole is longitudinally formed in the top surface of the electric sliding block (9).

3. A cooling crystallization apparatus for the production of amantadine hydrochloride according to claim 2, characterized in that: The vertical rod (10) slidingly penetrates the sliding hole formed in the side wall of the electric sliding block (9).

4. The apparatus for cooling and crystallization of amantadine hydrochloride according to claim 1, characterized in that: Limiting blocks (11) are symmetrically fixedly installed on the side wall of the electric sliding block (9), and two limiting grooves are symmetrically formed in the inner wall of the vertical groove.

5. A cooling crystallization apparatus for the production of amantadine hydrochloride according to claim 4, characterized in that: The limiting blocks (11) fixedly installed on the side wall of the electric sliding block (9) are slidingly connected in the interiors of the two limiting grooves formed in the inner wall of the vertical groove.

6. The apparatus for cooling and crystallization of amantadine hydrochloride according to claim 1, characterized in that: A rubber pad (12) is fixedly bonded to the outer wall of the installation frame (6), and the outer wall of the rubber pad (12) is slidingly attached to the inner wall of the precipitation tank (1).

7. The apparatus for cooling and crystallization of amantadine hydrochloride according to claim 1, characterized in that: Sealing rings (13) are fixedly sleeved on the outer walls of the two expansion pipes (5), and the outer walls of the sealing rings (13) are sealingly slidingly attached to the inner walls of the sleeve pipes (4).

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