Uterine cavity infusion tube and uterine cavity infusion device

Abstract

The utility model discloses a uterine cavity infusion tube and a uterine cavity infusion device, and relates to the technical field of medical instruments. The uterine cavity infusion tube comprises a confluence piece and a catheter; the confluence piece is provided with a confluence cavity, and a shell of the confluence cavity is provided with a liquid inlet and a public liquid outlet; a plurality of liquid inlets are provided; the liquid guide pipe comprises a communicating pipe and a filling head, and the communicating pipe is respectively communicated with the public liquid outlet and the filling head; a plurality of filling holes are formed in the filling head; and the plurality of filling holes are dispersedly distributed on the periphery of the filling head. According to the application, the distribution uniformity and the attachment stability of the PRP on the endometrium can be improved.

Description

Technical Field

[0001] This application relates to the field of medical device technology, and more specifically to intrauterine irrigation tubing and intrauterine irrigation devices. Background Technology

[0002] Intrauterine perfusion therapy involves injecting a repair agent into the uterine cavity. This agent promotes tissue repair, cell proliferation, and local angiogenesis, thereby improving thin endometrium and thickening the endometrium to facilitate embryo transfer.

[0003] Existing repair agents for the endometrium generally include platelet-rich plasma (PRP) and medical thickeners. These medical thickeners are biomaterials that enable PRP to adhere more firmly to the endometrium. For example, Chinese patent application CN202310936268.5 discloses a biomedical material capable of loading and controlling the release of PRP. The preparation process of this biomedical material involves mixing PRP with a hydrogel as a medical thickener. This allows the biomedical material to adhere well to the endometrium when infused into the uterine cavity as a repair agent, preventing it from detaching and thus avoiding backflow of the infused repair agent.

[0004] The infusion of the repair agent requires an infusion device. If the repair agent, which is mixed with PRP and medical adhesive, is left for a long time, its fluidity and adhesion will decrease, which will affect the uniformity of the distribution of the infused repair agent on the endometrium and the stability of its adhesion.

[0005] Therefore, how to improve the uniformity of distribution and adhesion stability of repair agents mixed with PRP and medical adhesives on the endometrium remains a technical problem that urgently needs to be solved by those skilled in the art. Utility Model Content

[0006] In view of this, in order to solve the above-mentioned technical problems, this application provides a uterine cavity irrigation tube and a uterine cavity irrigation device.

[0007] To solve the above-mentioned technical problems, one of the technical solutions adopted in this application is to provide a uterine cavity irrigation tube, which includes:

[0008] The manifold is provided with a manifold cavity, and the outer shell of the manifold cavity is provided with an inlet and a common outlet; there are multiple inlets.

[0009] The liquid guide tube includes a connecting tube and an injection head. The connecting tube connects to the common liquid outlet and the injection head respectively. The injection head is provided with multiple injection holes. The multiple injection holes are distributed around the outer periphery of the injection head.

[0010] To solve the above-mentioned technical problems, another technical solution adopted in this application is to provide a uterine cavity irrigation control system, the uterine cavity irrigation device comprising:

[0011] Intrauterine irrigation tube, the intrauterine irrigation tube is the one described above;

[0012] And multiple syringes, each connected to multiple inlet ports; each syringe is connected to one inlet port.

[0013] Beneficial Effects: Unlike existing technologies, in this application, when a repair agent needs to be infused into the uterine cavity, PRP and medical adhesive can enter the manifold through different inlets and mix to form the repair agent. The repair agent flows through the connecting tube to the infusion head and is ejected from the infusion orifice on the infusion head. Thus, the repair agent formed by mixing within the uterine cavity using the manifold has a short residence time outside the uterine cavity, resulting in good fluidity and adhesion when ejected from the infusion orifice. This improves the uniformity of distribution and adhesion stability of the repair agent mixed with platelets and medical adhesive on the endometrium. Attached Figure Description

[0014] Figure 1 This is a schematic diagram of the uterine cavity device according to Embodiment 1 of this application;

[0015] Figure 2 yes Figure 1 Schematic diagram of the intrauterine infusion cannula;

[0016] Figure 3 yes Figure 2 Enlarged schematic diagram of region A in the middle;

[0017] Figure 4 yes Figure 2 Dimensional diagram of the central cavity infusion tube;

[0018] Figure 5 yes Figure 3 A schematic diagram of the cross-section of the injection head;

[0019] Figure 6 This is a schematic diagram of the intrauterine perfusion device according to Embodiment 2 of this application.

[0020] Explanation of reference numerals in the attached figures:

[0021] Intrauterine irrigation device 10; intrauterine irrigation tube 100; manifold 110; manifold cavity 111; inlet 112; common outlet 113; contraction cavity 114; first end 115; second end 116; guide tube 120; connecting tube 121; irrigation head 122; irrigation hole 123; flow regulating valve 130; syringe 200; injection end 201; push-pull end 202; first region 203; third end 204; fourth end 205; first connector 300; fixing groove 301; first direction L; second direction C; length d1 of guide tube 120; outer diameter d2 of connecting tube 121; diameter d3 of irrigation hole 123; first dimension d4; second dimension d5. Detailed Implementation

[0022] To enable those skilled in the art to better understand the technical solutions of this application, the application will be further described in detail below with reference to the accompanying drawings and specific embodiments. Obviously, the described embodiments are only a part of the embodiments of this application, and not all of them. Based on the embodiments in this application, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of this application.

[0023] Example 1

[0024] Please see Figures 1-5 As shown, the intrauterine irrigation device 10 of this application includes an intrauterine irrigation tube 100 and a plurality of syringes 200. The intrauterine irrigation tube 100 includes a manifold 110 and a guide tube 120. The manifold 110 is provided with a manifold cavity 111, and the outer shell of the manifold cavity 111 is provided with an inlet 112 and a common outlet 113. There are multiple inlets 112. The guide tube 120 includes a connecting tube 121 and an irrigation head 122. The connecting tube 121 connects to the common outlet 113 and the irrigation head 122 respectively. The irrigation head 122 is provided with a plurality of irrigation holes 123. The plurality of irrigation holes 123 are distributed around the outer periphery of the irrigation head 122. The plurality of syringes 200 are respectively connected to the plurality of inlets 112. Each syringe 200 is connected to one inlet 112.

[0025] In this way, the raw materials for preparing the repair agent, such as PRP and medical adhesive, can be separately placed in different syringes 200. When the repair agent needs to be infused into the uterine cavity, the PRP and medical adhesive can enter the manifold 110 through different inlets 112 and mix to form the repair agent. The repair agent flows to the infusion head 122 through the connecting tube 121 and is sprayed out from the infusion hole 123 on the infusion head 122. In this way, the repair agent mixed in the uterine cavity in the infusion tube 100 by the manifold 110 has a short residence time outside the uterine cavity, so that the repair agent still has good fluidity and adhesion when it is sprayed out from the infusion hole 123, thereby improving the uniformity of distribution and adhesion stability of the repair agent mixed with PRP and medical adhesive on the endometrium.

[0026] Optionally, such as Figures 1-5 As shown, the number of inlets 112 of the manifold 110 can be greater than the number of syringes 200. In this case, the inlets 112 that are not connected to the syringes 200 can be covered by a cap (not shown), for example, the cap is threaded to the outer shell of the inlet 112 to cover the inlet 112.

[0027] Optionally, such as Figures 1-5 As shown, the manifold 110, connecting pipe 121, and injection head 122 are integrally connected, but not limited to this. This reduces the occurrence of leakage.

[0028] Optionally, such as Figures 1-5 As shown, the connecting tube 121 is a flexible tube, and the irrigation head 122 is made of the same material as the connecting tube 121. Thus, the length d1 of the fluid guide tube 120 has good bending and deformation capabilities, thereby reducing the pressure on the internal sidewall of the body during the insertion of the irrigation head 122 into the uterine cavity. It should be noted that in other embodiments, the connecting tube 121 can also be a rigid tube.

[0029] Optionally, such as Figures 1-5 As shown, multiple irrigation holes 123 are distributed along a first direction L and a second direction C on the outer periphery of the irrigation head 122. The first direction L is the length direction of the portion of the fluid guide tube 120 located in the irrigation head 122. The second direction C is the circumferential direction around the first direction L. In this way, the irrigation holes 123 are distributed relatively evenly on the outer periphery of the irrigation head 122, so that the repair agent sprayed through the multiple irrigation holes 123 can be more evenly distributed on the endometrium.

[0030] Optionally, such as Figures 1-5As shown, at least the portion of the manifold 111 near the common outlet 113 is formed as a constriction cavity 114, which is shaped to gradually converge toward the common outlet 113 along the direction of proximity to it. This shape of the constriction cavity 114 guides the flow of PRP and medical viscous agent into the manifold 111, gradually compressing the space between them as they flow toward the common outlet 113, thus improving the mixing effect and enhancing the uniformity of PRP dispersion within the viscous agent.

[0031] Optionally, such as Figures 1-5 As shown, the outer shell of the manifold 111 has a first end 115 and a second end 116. Multiple liquid inlets 112 are located at the first end 115, and a common liquid outlet 113 is located at the second end 116. The first end 115 and the second end 116 are opposite ends of the manifold 110. This reduces the bends and turns of the fluid within the manifold 111, thus improving the smoothness of fluid flow within the manifold.

[0032] Optionally, such as Figures 1-5 As shown, a flow regulating valve 130 is connected in series between the liquid inlet 112 and the syringe 200. In this way, the flow rate of the liquid inlet 112 can be adjusted by the flow regulating valve 130, so as to reasonably control the flow rate of each liquid inlet 112.

[0033] Optionally, such as Figures 1-5 As shown, the length d1 of the drainage tube 120 is 60-100cm. For example, the length d1 of the drainage tube 120 is including but not limited to 60cm, 80cm, or 100cm. Preferably, the length d1 of the drainage tube 120 is 75-85cm. For example, the length d1 of the drainage tube 120 is including but not limited to 75cm, 80cm, or 85cm. The length d1 of the drainage tube 120 is not too long because if the length d1 of the drainage tube 120 is too long, the following two problems will exist. First, the drainage tube 120 will be inconvenient to place during intrauterine irrigation treatment. Second, the resistance encountered by the repair agent when flowing within the drainage tube 120 will be relatively large, which will limit the flowability of the repair agent and thus affect the spraying effect of the irrigation hole 123.

[0034] Optionally, such as Figures 1-5 As shown, the outer diameter d2 of the connecting tube 121 is 0.4~0.6cm, and the orifice diameter d3 of the irrigation hole 123 is 0.07~0.13cm. Thus, because the orifice diameter d3 of the irrigation hole 123 is much smaller than the outer diameter d2 of the connecting tube 121, the repair agent ejected from the irrigation hole 123 has sufficient kinetic energy to be sprayed onto the endometrium.

[0035] Optionally, such as Figures 1-5 As shown, the outer diameter d2 of the connecting pipe 121 is, but is not limited to, 0.4cm, 0.5cm or 0.6cm, and the diameter d3 of the injection hole 123 is, but is not limited to, 0.07cm, 0.1cm or 0.13cm.

[0036] Optionally, such as Figures 1-5 As shown, the third direction is defined as the interval between the first end 115 and the second end 116, and the fourth direction is defined as perpendicular to the third direction. The maximum dimension of the manifold 111 along the third direction is the first dimension d4, and the maximum dimension of the manifold 111 along the fourth direction is the second dimension d5. The second dimension d5 is smaller than the first dimension d4. By rationally designing the dimensions of the manifold 111, PRP and medical adhesive can be rapidly mixed within the manifold 111.

[0037] Optionally, such as Figures 1-5 As shown, the first dimension d4 is 0.7~1.5cm, and the second dimension d5 is 0.3~1cm. The first dimension d4 is including but not limited to 0.7cm, 1cm or 1.5cm, and the second dimension d5 is including but not limited to 0.3cm, 0.5cm or 1cm.

[0038] For example, and not as a limitation, in a specific example, the first dimension d4 is 1 cm, the second dimension d5 is 0.5 cm, the length d1 of the liquid guide tube 120 is 80 cm, the outer diameter d2 of the connecting tube 121 is 0.5 cm, and the diameter d3 of the injection hole 123 is 0.1 cm.

[0039] Example 2

[0040] Example 2 is derived from Example 1. The similarities between Example 2 and Example 1 will not be repeated. The differences between Example 2 and Example 1 are as follows.

[0041] Combination Figures 1-5 See Figure 6 As shown, syringe 200 has an injection end 201 and a push-pull end 202. The injection end 201 is connected to a corresponding inlet 112. In a single syringe 200, the syringe 200 performs an injection action when the push-pull end 202 moves closer to the injection end 201.

[0042] The intrauterine irrigation device 10 includes a first connector 300, and a first region 203 is formed by arranging multiple syringes 200. The first region 203 has a third end 204 facing the manifold 110 and a fourth end 205 facing away from the manifold 110. The first connector 300 is located on the side where the fourth end 205 is located, and the push-pull ends 202 of the multiple syringes 200 are respectively connected to the first connector 300. When the first connector 300 is moved closer to the third end 204, the connecting plate can move the push-pull ends 202 of the multiple syringes 200 closer to the corresponding injection ends 201.

[0043] Optionally, the first connector 300 has multiple fixing slots 301 on the side facing the first region 203. The push-pull end 202 of the syringe 200 is detachably fixed to the fixing slot 301, and the injection end 201 of the syringe 200 is detachably connected to the inlet 112. This facilitates the removal of the syringe 200 for replacement. The injection end 201 of the syringe 200 and the housing of the inlet 112 can be threaded together to achieve a detachable connection between the injection end 201 of the syringe 200 and the inlet 112.

[0044] The following specific examples illustrate how to use the intrauterine irrigation device 10.

[0045] Specific Example 1

[0046] Specific embodiment one includes the following steps S110 to S140.

[0047] Step S110: Provide two syringes 200, PRP and medical thickener, the two syringes being the first syringe and the second syringe, the PRP being platelet plasma, and the medical thickener being gelatin.

[0048] Step S120: The first syringe draws in PRP, and the second syringe draws in gelatin.

[0049] Step S130: Connect the first syringe and the second syringe to different inlet ports 112 respectively, so that the first syringe, the second syringe and the uterine cavity irrigation tube 100 form a uterine cavity irrigation device 10.

[0050] Step S140: Using the first and second syringes, PRP and gelatin are injected into the manifold 110, so that PRP and gelatin are mixed to form a repair agent, which is then sprayed onto the endometrium through multiple irrigation holes 123 after passing through the drainage tube 120.

[0051] It should be noted that after PRP and gelatin are mixed to form a repair agent, the repair agent will solidify into a gel within a short time. Therefore, preferably, completing step S140 within 2 seconds allows the repair agent to be sprayed out from the infusion hole 123 before it has completely solidified into a gel. This has at least two beneficial effects. First, when the repair agent has not completely solidified into a gel, it is easier to spray out from the infusion hole 123, and it still has sufficient fluidity after spraying to spread on the endometrium, thereby improving the uniformity of its distribution on the endometrium. Second, the repair agent can gradually solidify during its diffusion on the endometrium, thereby enhancing its adhesion to the endometrium.

[0052] Specific Example 2

[0053] Specific embodiment one includes the following steps S210 to S240.

[0054] Step S210: Provide three syringes 200, PRP and medical thickener, the three syringes being a first syringe, a second syringe and a third syringe, the PRP being platelet plasma, and the medical thickener being fibrin and coagulation factors.

[0055] Step S220: The first syringe aspirates PRP, the second syringe aspirates fibrin, and the third syringe aspirates clotting factors.

[0056] Step S230: Connect the first syringe, the second syringe, and the third syringe to different inlets 112, so that the first syringe, the second syringe, the third syringe, and the uterine cavity irrigation tube 100 form a uterine cavity irrigation device 10.

[0057] Step S240: Using the first syringe, the second syringe and the third syringe, PRP, fibrin and coagulation factors are injected into the manifold 110, so that PRP, fibrin and coagulation factors are mixed to form a repair agent and sprayed onto the endometrium through multiple irrigation holes after passing through the drainage tube.

[0058] It should be noted that after PRP and gelatin are mixed to form a repair agent, the repair agent will solidify into a gel within a short time. Therefore, preferably, completing step S140 within 2 seconds allows the repair agent to be sprayed out from the infusion hole 123 before it has completely solidified into a gel. This has at least two beneficial effects. First, when the repair agent has not completely solidified into a gel, it is easier to spray out from the infusion hole 123, and it still has sufficient fluidity after spraying to spread on the endometrium, thereby improving the uniformity of its distribution on the endometrium. Second, the repair agent can gradually solidify during its diffusion on the endometrium, thereby enhancing its adhesion to the endometrium.

[0059] The above are merely embodiments of this application and do not limit the scope of this patent application. Any equivalent structural or procedural changes made using the content of this application's specification and drawings, or direct or indirect applications in other related technical fields, are similarly included within the scope of patent protection of this application.

Claims

1. A uterine cavity irrigation tube, characterized in that, The intrauterine irrigation cannula includes: A manifold is provided with a manifold cavity, and the outer shell of the manifold cavity is provided with an inlet and a common outlet; the inlet has multiple outlets. The system includes a liquid guide tube, comprising a connecting tube and an injection head, wherein the connecting tube is connected to the common liquid outlet and the injection head respectively; the injection head is provided with a plurality of injection holes; the plurality of injection holes are distributed on the outer periphery of the injection head.

2. The intrauterine irrigation cannula according to claim 1, characterized in that, The connecting tube is a flexible tube, and the injection head is made of the same material as the connecting tube.

3. The intrauterine irrigation cannula according to claim 1, characterized in that, The plurality of injection holes are distributed along a first direction and a second direction on the outer periphery of the injection head; the first direction is the length direction of the liquid guide tube located on the injection head portion; the second direction is the circumferential direction around the first direction.

4. The intrauterine irrigation cannula according to claim 1, characterized in that, At least the portion of the manifold near the common outlet is formed as a constricted cavity, which is shaped to gradually converge toward the common outlet along the direction of proximity to the common outlet.

5. The intrauterine irrigation cannula according to claim 1, characterized in that, The outer shell of the manifold has a first end and a second end; a plurality of liquid inlets are disposed at the first end, and a common liquid outlet is disposed at the second end; wherein the first end and the second end are opposite ends of the manifold.

6. The intrauterine irrigation cannula according to claim 1, characterized in that, A flow regulating valve is connected in series between the inlet and the syringe.

7. The intrauterine irrigation cannula according to claim 1, characterized in that, The length of the liquid guiding tube is 60~100cm; the outer diameter of the connecting tube is 0.4~0.6cm; and the diameter of the injection hole is 0.07~0.13cm.

8. A uterine cavity perfusion device, characterized in that, The intrauterine perfusion device includes: The intrauterine irrigation tube is the intrauterine irrigation tube according to any one of claims 1 to 7; And a plurality of syringes, each connected to a plurality of liquid inlets; each syringe is connected to one of the liquid inlets.

9. The intrauterine irrigation device according to claim 8, characterized in that, The syringe has an injection end and a push-pull end; the injection end is connected to the corresponding liquid inlet; in a single syringe, when the push-pull end moves closer to the injection end, the syringe performs an injection action; The uterine irrigation device includes a first connector, and the arrangement area of ​​the plurality of syringes is a first region; the first region has a third end facing the manifold and a fourth end facing away from the manifold; the first connector is located on the side where the fourth end is located, and the push-pull ends of the plurality of syringes are respectively connected to the first connector; when the first connector is moved closer to the third end, the connecting plate can move the push-pull ends of the plurality of syringes closer to the corresponding injection ends.

10. The intrauterine irrigation device according to claim 9, characterized in that, The first connector has a plurality of fixing grooves on the side facing the first region; the push-pull end of the syringe is detachably fixed to the fixing groove, and the injection end of the syringe is detachably connected to the inlet.

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