Micropipettor for detection

Abstract

The utility model provides a micropipettor for detection, which relates to the field of micropipettors, and comprises a main body, and a suction head is mounted at the lower end of the main body; a clamping and fixing mechanism is installed on the upper portion of the left side of the body, and a perpendicularity measuring mechanism is arranged on the lower portion of the front end face of the body. Through the arrangement of the perpendicularity measuring mechanism, when liquid to be detected is sucked, the indicating arrow is always in a vertical state, and then the perpendicularity of the micropipettor is quickly measured through the indicating arrow and the angle measuring scale, so that the perpendicularity deviation between the micropipettor and the liquid level can be quickly and intuitively judged; the phenomenon of inaccurate judgment is avoided, and the accuracy of the pipetting amount is remarkably improved; the problems that when a traditional micropipettor sucks liquid, due to the fact that an effective perpendicularity measuring structure is lacked on the micropipettor, an experimenter judges whether the liquid suction angle is perpendicular or not only depending on personal experience and vision, judgment is inaccurate, and the liquid relief error is increased are solved.

Description

TECHNICAL FIELD

[0001] The utility model relates to micro pipette technical field especially relates to a micro pipette for detection. BACKGROUND

[0002] Parkinson's disease is a common neurodegenerative disease, and its characteristic performance is motor dysfunction, such as tremor, stiffness and bradykinesia. At present, the diagnosis of Parkinson's disease mainly depends on the observation of clinical symptoms, but this method is often difficult to accurately identify in the early stage of the disease, leading to delayed diagnosis and thus affecting the treatment effect. In recent years, with the in-depth of biomedical research, more and more evidence shows that there are specific biomarkers in human plasma, and these markers are closely related to the occurrence and development of Parkinson's disease. When measuring the Parkinson's disease biomarkers in human plasma, a micro pipette will be used.

[0003] In the process of sucking liquid, the traditional micro pipette needs to maintain good verticality to ensure the accuracy of liquid volume and avoid the appearance of residual and bubbles. However, in actual operation, when the traditional micro pipette sucks liquid, due to the lack of effective verticality measurement structure on the micro pipette, the experimenter only relies on personal experience and vision to judge whether the liquid suction angle is vertical. This way is easily affected by human factors, leading to inaccurate judgment. For example, in the long-term experimental operation, the experimenter may have visual fatigue due to fatigue and other reasons, especially for the interns, which makes it difficult to accurately judge the verticality of the liquid suction process, further increasing the risk of pipetting error. UTILITY MODEL CONTENT

[0004] The utility model relates to a micro pipette for detection, which is provided with a verticality measurement mechanism. When sucking the liquid to be detected, the vertical rod, L-shaped fixed plate and indication arrow are always in a vertical state under the action of gravity. Then, the verticality of the micro pipette is quickly measured by the indication arrow and angle measurement scale, so that the deviation of the verticality of the micro pipette and the liquid surface can be quickly and intuitively judged, avoiding inaccurate judgment and significantly improving the accuracy of the pipetting volume. The utility model is provided with a clamping and fixing mechanism. When holding the main body, the experimenter's right hand can be clamped by the movable clamping plate and sponge pad. The sponge pad forms a flexible clamping, improving the comfort during clamping and avoiding the phenomenon of micro pipette dropping due to experimenter's hand fatigue and operation error.

[0005] The utility model discloses a first aspect provides a kind of detection with micro pipette, specifically includes: main body, the main body lower end is equipped with suction head;The main body left side upper portion is equipped with clamping fixed mechanism, and the main body front end surface lower part is provided with perpendicularity measuring mechanism;The perpendicularity measuring mechanism includes rotating shaft and angle measuring scale, the rotating shaft is installed in main body front end surface lower side middle part, and rotating shaft outside rotation is connected with shaft sleeve, the shaft sleeve bottom is fixedly connected with vertical rod, and vertical rod lower end is fixedly connected with counterweight, and the counterweight lower end shape is conical;The vertical rod outside is fixedly connected with L type fixed plate, and L type fixed plate lower end is fixedly connected with indicating arrow;The angle measuring scale is fixedly installed in main body front end surface lower part, and angle measuring scale is located indicating arrow rear side, and the angle measuring scale front side is provided with angle scale line.

[0006] Further, the clamping fixed mechanism includes a H-shaped fixed plate, the H-shaped fixed plate is fixedly connected to the left side of the main body, and a sliding guide rod is slidably connected to the H-shaped fixed plate, and a movable clamp plate is fixedly connected to the right end of the sliding guide rod.

[0007] Further, a first pinch block is fixedly connected to the middle of the front end surface of the movable clamp plate, and a second pinch block is fixedly connected to the middle of the front side of the H-shaped fixed plate.

[0008] Further, the external spring of the sliding guide rod is located inside the H-shaped fixed plate, and the external spring of the sliding guide rod is also located to the left side of the movable clamp plate.

[0009] Further, a sponge pad is provided on the right side of the movable clamp plate, and a hook is fixedly connected to the top of the H-shaped fixed plate.

[0010] The utility model provides a kind of detection with micro pipette, with following beneficial effects:

[0011] 1. By the setting of the perpendicularity measuring mechanism, when the liquid to be detected is sucked, the counterweight will be vertically downward under the action of gravity, so that the vertical rod, the L-shaped fixed plate and the indicating arrow are always in a vertical state, and then the perpendicularity of the micro pipette is quickly measured by the indicating arrow and the angle measuring scale, so that the deviation of the perpendicularity of the micro pipette and the liquid surface can be quickly and intuitively judged, and the phenomenon of inaccurate judgment is avoided, the accuracy of the pipetting volume is significantly improved, and reliable protection is provided for the accurate detection of Parkinson's disease biomarkers and other samples.

[0012] 2. By the setting of the clamping fixing mechanism, the right hand of the experimenter can be clamped by the movable clamping plate and the sponge pad when holding the main body, and the flexible clamping can be formed by the setting of the sponge pad, the comfort degree during clamping is improved, the phenomenon that the micropipette is dropped due to the fatigue of the hand of the experimenter and the operation error is avoided, and therefore the reliability of the experimenter when using the micropipette is improved, and the micropipette is prevented from being damaged due to falling. BRIEF DESCRIPTION OF DRAWINGS

[0013] In order to more clearly illustrate the technical scheme of the present application, the drawings of the present application will be briefly introduced as follows.

[0014] In the drawings:

[0015] Figure 1 A structure schematic view of a first perspective of the present application is shown;

[0016] Figure 2 A structure schematic view of a second perspective of the present application is shown;

[0017] Figure 3 A structure schematic view of the present application in a split state is shown;

[0018] Figure 4 A structure schematic view of the present application is shown; Figure 1 A structure schematic view of a local amplification at A of the present application is shown;

[0019] Figure 5 A structure schematic view of a front view of the perpendicularity measuring mechanism of the present application is shown.

[0020] LIST OF REFERENCE NUMERALS

[0021] 1. main body; 101, suction head;

[0022] 2. clamping fixing mechanism; 201, Z-shaped fixed plate; 202, sliding guide rod; 203, movable clamping plate; 204, sponge pad; 205, first pinch block; 206, second pinch block; 207, hook;

[0023] 3. perpendicularity measuring mechanism; 301, rotating shaft; 302, shaft sleeve; 303, vertical rod; 304, counterweight; 305, L-shaped fixed plate; 306, angle measuring scale; 307, indicating arrow. DETAILED DESCRIPTION

[0024] In order to make the purpose, technical scheme and advantages of the embodiments of the utility model clearer, the technical scheme of the embodiments of the utility model will be described clearly and completely below in combination with the drawings of the embodiments of the utility model. Obviously, the described embodiments are part of the embodiments of the utility model, rather than all the embodiments. Based on the described embodiments of the utility model, all other embodiments obtained by those of ordinary skill in the art without creative labor fall within the scope of the utility model.

[0025] Embodiment one: please refer to Figures 1 to 5 :

[0026] The utility model proposes a kind of micro pipettor for detection, it include: main body 1, suction head 101 is installed in main body 1 lower end;Clamping fixed mechanism 2 is installed in the left upper portion of main body 1, and the lower part of the front end surface of main body 1 is provided with perpendicularity measuring mechanism 3;Perpendicularity measuring mechanism 3 includes rotating shaft 301 and angle measuring scale 306, rotating shaft 301 is installed in the lower side middle part of the front end surface of main body 1, and rotating shaft 301 is rotatably connected with shaft sleeve 302 outside, shaft sleeve 302 bottom is fixedly connected with vertical rod 303, and vertical rod 303 lower end is fixedly connected with counterweight 304, and the shape of counterweight 304 lower end is tapered, ensure that vertical rod 303 can always keep good perpendicularity.

[0027] Vertical rod 303 is fixedly connected with L-shaped fixed plate 305 outside, and L-shaped fixed plate 305 lower end is fixedly connected with indicating arrow 307;Angle measuring scale 306 is fixedly installed in the lower part of the front end surface of main body 1, and angle measuring scale 306 is located at the rear side of indicating arrow 307, and angle scale is provided on the front side of angle measuring scale 306;By the setting of perpendicularity measuring mechanism 3, when taking the liquid to be detected, under the action of gravity, counterweight 304 will be vertically downward, so that vertical rod 303, L-shaped fixed plate 305 and indicating arrow 307 are always in vertical state, then the perpendicularity of the micro pipettor is measured quickly by indicating arrow 307 and angle measuring scale 306, so that the perpendicularity deviation of the micro pipettor and liquid level can be quickly and intuitively judged, to avoid the phenomenon of inaccurate judgment, significantly improve the accuracy of pipetting volume.

[0028] Embodiment two, on the basis of embodiment one, such as Figures 1 to 3As shown, the clamping and fixing mechanism 2 comprises a H-shaped fixing plate 201 fixedly connected to the left side of the main body 1, and a sliding guide rod 202 slidingly connected to the H-shaped fixing plate 201, and the right end of the sliding guide rod 202 is fixedly connected with a movable clamping plate 203, and a spring is sleeved outside each sliding guide rod 202; the front end surface of the movable clamping plate 203 is fixedly connected with a first pinch block 205, and the middle part of the front side of the H-shaped fixing plate 201 is fixedly connected with a second pinch block 206; the external spring of the sliding guide rod 202 is located inside the H-shaped fixing plate 201, and the external spring of the sliding guide rod 202 is also located to the left of the movable clamping plate 203; the right side surface of the movable clamping plate 203 is provided with a sponge pad 204; through the setting of the clamping and fixing mechanism 2, when holding the main body 1, the right hand of the experimenter can be clamped by the movable clamping plate 203 and the sponge pad 204, thereby avoiding the phenomenon that the micropipette is dropped due to hand fatigue and operation error of the experimenter, and thus the reliability of the experimenter in using the micropipette is improved.

[0029] The top of the H-shaped fixing plate 201 is fixedly connected with a hook 207, which is used to hang the micropipette on the pipette support when not in use.

[0030] The working principle of the embodiment is as follows: in use, first, the experimenter inserts the right hand between the sponge pad 204 and the opposite surface of the main body 1, and then releases the first pinch block 205 and the second pinch block 206, so that the movable clamping plate 203 moves rightward under the elastic force of the external spring of the sliding guide rod 202, and the right hand of the experimenter is clamped by the rightward moving sponge pad 204, thereby avoiding the phenomenon that the main body 1 is dropped (the experimenter is prone to drop the micropipette due to hand muscle fatigue when using the traditional micropipette for a long time), and thus the reliability of the experimenter in holding the main body 1 is improved, and the micropipette is prevented from being damaged due to falling.

[0031] When the liquid to be detected is sucked, the micropipette is first placed vertically above the container of the liquid to be detected, and under the action of gravity, the counterweight 304 moves vertically downward, so that the vertical rod 303, the L-shaped fixing plate 305 and the indicating arrow 307 are always in a vertical state, and then the verticality of the micropipette is quickly measured by the indicating arrow 307 and the angle measuring scale 306, and if the inclination angle is too large, it can be quickly adjusted to ensure that the micropipette can maintain good verticality when sucking the liquid, and the phenomenon of inaccurate judgment can be avoided, so that the verticality of the liquid sucking process can be more accurately judged, and the risk of pipetting error is greatly reduced.

[0032] In this paper, the following points need to be noted:

[0033] 1. The accompanying drawings of this utility model only relate to the structures involved in this utility model; other structures can be referred to conventional designs.

[0034] 2. Where there is no conflict, the embodiments of this utility model and the features in the embodiments can be combined with each other to obtain new embodiments.

[0035] The above are merely specific embodiments of this utility model, but the protection scope of this utility model is not limited thereto. Any variations or substitutions that can be easily conceived by those skilled in the art within the technical scope disclosed in this utility model should be included within the protection scope of this utility model. Therefore, the protection scope of this utility model should be determined by the scope of the claims.

Claims

1. A micropipette for detection, comprising: The main body (1) has a suction head (101) installed at its lower end. The main body (1) is characterized by having a clamping and fixing mechanism (2) installed on the upper left side and a verticality measuring mechanism (3) installed on the lower front end face of the main body (1). The verticality measuring mechanism (3) includes a rotating shaft (301) and an angle measuring ruler (306). The rotating shaft (301) is installed in the middle of the lower side of the front end face of the main body (1), and a bushing (302) is rotatably connected to the outside of the rotating shaft (301). A vertical rod (303) is fixedly connected to the bottom of the bushing (302), and a counterweight (304) is fixedly connected to the lower end of the vertical rod (303). An L-shaped fixing plate (305) is fixedly connected to the outside of the vertical rod (303), and an indicator arrow (307) is fixedly connected to the lower end of the L-shaped fixing plate (305). The angle measuring ruler (306) is fixedly installed on the lower front end face of the main body (1).

2. The micropipette for detection according to claim 1, characterized in that: The clamping and fixing mechanism (2) includes a U-shaped fixing plate (201), which is fixedly connected to the left side of the main body (1). A sliding guide rod (202) is slidably connected to the U-shaped fixing plate (201), and a movable clamping plate (203) is fixedly connected to the right end of the sliding guide rod (202). A spring is sleeved on the outside of each sliding guide rod (202).

3. A micropipette for detection according to claim 2, characterized in that: A first pinch block (205) is fixedly connected to the middle of the front end face of the movable clamping plate (203), and a second pinch block (206) is fixedly connected to the middle of the front side of the U-shaped fixing plate (201).

4. A micropipette for detection according to claim 2, characterized in that: The external spring of the sliding guide rod (202) is located inside the U-shaped fixing plate (201), and the external spring of the sliding guide rod (202) is also located on the left side of the movable clamping plate (203).

5. A micropipette for detection according to claim 2, characterized in that: A sponge pad (204) is provided on the right side of the movable clamp (203); a hook (207) is fixedly connected to the top of the U-shaped fixing plate (201).

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