Biopharmaceutical fermentation tank
By introducing handling and cleaning mechanisms into biopharmaceutical fermenters, the problems of inconvenient cleaning and sterilization dead spots in existing technologies have been solved, enabling convenient cleaning and sealing of fermenters and improving their practicality.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2025-04-17
- Publication Date
- 2026-04-07
AI Technical Summary
Existing biopharmaceutical fermenters are inconvenient to clean, and the fixed connection between the stirring mechanism and the tank body makes cleaning and maintenance cumbersome. They also have sterilization dead spots and are prone to contamination, which reduces the practicality of the fermenters.
A biopharmaceutical fermenter was designed, comprising a frame, mounting ring, fermentation tank, sealing cover, stirring mechanism, locking mechanism, transport mechanism, and cleaning mechanism. The stirring mechanism is moved to the cleaning mechanism for all-round cleaning via the transport mechanism. The locking mechanism ensures the sealing of the fermentation tank, and the cleaning mechanism enables convenient cleaning and avoids sterilization dead spots.
It enables convenient cleaning of fermenters, ensures cleaning quality, avoids sterilization dead spots, improves the practicality and sealing of fermenters, and ensures the effectiveness of the stirring and fermentation process.
Smart Images

Figure CN224091866U_ABST
Abstract
Description
Technical Field
[0001] This utility model relates to the field of biopharmaceutical fermentation tank technology, and in particular to a biopharmaceutical fermentation tank. Background Technology
[0002] Pharmaceutical engineering is an interdisciplinary engineering discipline that combines chemistry, biology, pharmacy (traditional Chinese medicine), and engineering. In the training of traditional Chinese medicine practitioners, in addition to learning basic drug knowledge, practical skills in drug preparation and production are also particularly important. Fermentation has always been an indispensable and important pharmaceutical method.
[0003] The existing biopharmaceutical fermenters have the following problems compared to existing technologies: they are inconvenient to clean, the stirring mechanism of the fermenter is fixedly connected to the tank body, and the entire stirring mechanism needs to be disassembled for cleaning and maintenance, which is cumbersome and has sterilization dead spots. When fermenting and stirring new materials, contamination is easily caused, which reduces the practicality of the fermenter. To address these issues, we propose a biopharmaceutical fermenter. Utility Model Content
[0004] The purpose of this invention is to overcome the shortcomings of the existing technology and provide a biopharmaceutical fermentation tank.
[0005] The present invention solves its technical problem through the following technical solution: It includes a frame, an mounting ring fixed to the inner wall of the frame by bolts, a fermentation mechanism fixed to the inner wall of the mounting ring, the fermentation mechanism including a fermentation tank, the fermentation tank fixed to the inner wall of the mounting ring by bolts, a discharge pipe fixed to the bottom of the fermentation tank, a sealing cover provided at the top of the fermentation tank, an inlet pipe fixed to the outside of the sealing cover, a stirring mechanism provided at the top of the sealing cover, a locking mechanism provided on the outside of the fermentation tank, and a transport mechanism provided at the top of the frame.
[0006] The conveying mechanism includes a mounting slide, which is fixed to the top of the frame by bolts. A drive motor is fixed to one side of the mounting slide by bolts. A lead screw is provided at the output end of the drive motor. A sliding seat is provided on the outside of the lead screw. A hydraulic rod B is fixed to the top of the sliding seat. A connecting bracket is fixed to the bottom of the hydraulic rod B. The connecting bracket is fixedly connected to the sealing cover. A cleaning mechanism is provided on one side of the mounting ring.
[0007] As a further improvement of this utility model, a control panel is provided on one side of the frame.
[0008] As a further embodiment of this utility model: the stirring mechanism includes a motor mounting base, which is fixed to the top of the sealing cover by bolts. A servo motor is fixed to the top of the motor mounting base by bolts. A drive shaft is provided at the output end of the servo motor, and a stirring frame is fixed to the bottom of the drive shaft.
[0009] As a further embodiment of this utility model: the locking mechanism includes a mounting block, which is fixed to the outside of the fermentation tank by bolts, a hydraulic rod A is fixed to one side of the mounting block, and a locking block is fixed to one end of the hydraulic rod A.
[0010] As a further improvement of this utility model: a limiting slider is fixed on the outer side of the sliding seat, and the limiting slider is slidably connected to the mounting groove.
[0011] As a further embodiment of this utility model: the cleaning mechanism includes a mounting bracket, which is fixed to the inner wall of the frame by bolts, a cleaning tank is fixed to the inner wall of the mounting bracket, and a drain pipe is fixed to the bottom of the cleaning tank.
[0012] In summary, due to the adoption of the above technical solution, the beneficial effects of this utility model are:
[0013] 1. When the stirring mechanism needs to be cleaned, the locking mechanism releases the sealing cover, and the stirring mechanism is moved to the cleaning mechanism by the conveying mechanism. The cleaning mechanism then cleans the stirring mechanism and the sealing cover from all angles. At this time, the fermentation tank is in an open state, which allows for convenient cleaning of the fermentation tank. This enables convenient cleaning of the fermentation tank, ensures the quality of the cleaning operation, avoids sterilization dead spots, and improves the practicality of the fermentation tank.
[0014] 2. By setting a locking mechanism, when the material is stirred and fermented, the locking block is engaged with the edge of the fermentation tank and the sealing cover, which can fix the fermentation tank and the sealing cover together, ensuring the airtightness of the fermentation tank during stirring and fermentation;
[0015] 3. By setting a limit slider to limit the movement of the sliding block, the stability of the handling operation is ensured. Attached Figure Description
[0016] Figure 1 A schematic diagram of an isometric structure according to an embodiment of the present invention is shown;
[0017] Figure 2 A schematic diagram of an isometric sectional view of a structure according to an embodiment of the present invention is shown;
[0018] Figure 3 The present invention provides an embodiment of the present invention. Figure 2Enlarged structural diagram of part A in the middle;
[0019] Figure 4 The present invention provides an embodiment of the present invention. Figure 2 Enlarged structural diagram of section B in the middle;
[0020] Figure 5 A schematic diagram of the front cross-sectional structure according to an embodiment of the present invention is shown;
[0021] Figure 6 The present invention provides an embodiment of the present invention. Figure 5 Enlarged structural diagram of section C.
[0022] Legend:
[0023] 100 Frame, 110 Control Panel, 120 Mounting Ring, 210 Fermentation Tank, 220 Discharge Pipe, 230 Sealing Cover, 240 Inlet Pipe, 310 Motor Mounting Base, 320 Servo Motor, 330 Drive Shaft, 340 Mixing Rack, 410 Mounting Block, 420 Hydraulic Rod A, 430 Locking Block, 510 Mounting Slide, 520 Drive Motor, 521 Lead Screw, 530 Sliding Seat, 531 Limiting Slider, 540 Hydraulic Rod B, 550 Connecting Bracket, 610 Mounting Bracket, 620 Cleaning Tank, 630 Drain Pipe. Detailed Implementation
[0024] In the description of this utility model, it should be understood that the terms "center," "longitudinal," "transverse," "length," "width," "thickness," "upper," "lower," "front," "rear," "left," "right," "vertical," "horizontal," and "top" are used interchangeably.
[0025] The orientation or positional relationship indicated by terms such as "bottom", "inner", "outer", "clockwise", and "counterclockwise" is based on the orientation or positional relationship shown in the accompanying drawings. It is only for the purpose of facilitating the description of this utility model and simplifying the description, and is not intended to indicate or imply that the device or component referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, it should not be construed as a limitation of this utility model.
[0026] In the description of this utility model, "multiple" means two or more, unless otherwise explicitly specified.
[0027] In the description of this utility model, it should be noted that, unless otherwise explicitly specified and limited, the terms "installed," "equipped with," "sleeved / connected," "connected," etc., should be interpreted broadly. For example, "connection" can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediate medium; it can be a connection within two components. Those skilled in the art can understand the specific meaning of the above terms in this utility model based on the specific circumstances.
[0028] Please see Figure 1-6 This utility model provides a technical solution: it includes a frame 100, a control panel 110 is provided on one side of the frame 100, an mounting ring 120 is fixed to the inner wall of the frame 100 by bolts, a fermentation mechanism is fixed to the inner wall of the mounting ring 120, the fermentation mechanism includes a fermentation tank 210, a discharge pipe 220 and a sealing cover 230, an inlet pipe 240 is fixed to the outer side of the sealing cover 230, a stirring mechanism is provided on the top of the sealing cover 230, a locking mechanism is provided on the outer side of the fermentation tank 210, and a transport mechanism is provided on the top of the frame 100;
[0029] The transport mechanism includes a mounting slide 510, a drive motor 520, a lead screw 521, and a sliding seat 530. A hydraulic rod B540 is fixed to the top of the sliding seat 530, and a connecting bracket 550 is fixed to the bottom of the hydraulic rod B540. The connecting bracket 550 is fixedly connected to the sealing cover 230. A cleaning mechanism is provided on one side of the mounting ring 120. When the stirring mechanism needs to be cleaned, the locking mechanism releases the locking of the sealing cover 230, and the transport mechanism drives the stirring mechanism to the cleaning mechanism. The cleaning mechanism cleans the stirring mechanism and the sealing cover 230 from all angles. At this time, the fermentation tank 210 is in an open state, which allows for convenient cleaning of the fermentation tank 210. This enables convenient cleaning of the fermentation tank, ensures the quality of the cleaning operation, avoids sterilization dead spots, and improves the practicality of the fermentation tank.
[0030] Specifically, the stirring mechanism includes a motor mounting base 310, which is fixed to the top of the sealing cover 230 by bolts. A servo motor 320 is fixed to the top of the motor mounting base 310 by bolts. A drive shaft 330 is provided at the output end of the servo motor 320, and a stirring frame 340 is fixed to the bottom of the drive shaft 330. By providing the stirring mechanism, the material is injected into the fermentation tank 210 through the feed pipe 240, and the stirring frame 340 performs stirring and fermentation operations on the material.
[0031] Specifically, the locking mechanism includes a mounting block 410, which is fixed to the outside of the fermentation tank 210 by bolts. A hydraulic rod A420 is fixed to one side of the mounting block 410, and a locking block 430 is fixed to one end of the hydraulic rod A420. By providing the locking mechanism, when the material is stirred and fermented, the locking block 430 is engaged with the edges of the fermentation tank 210 and the sealing cover 230, which can fix the fermentation tank 210 and the sealing cover 230 together, ensuring the sealing of the fermentation tank during stirring and fermentation.
[0032] Specifically, a limiting slider 531 is fixed on the outer side of the sliding seat 530, and the limiting slider 531 is slidably connected to the mounting groove 510; by setting the limiting slider 531 to limit and support the movement of the sliding seat 530, the stability of the handling operation is ensured.
[0033] Specifically, the cleaning mechanism includes a mounting bracket 610, which is fixed to the inner wall of the frame 100 by bolts. A cleaning tank 620 is fixed to the inner wall of the mounting bracket 610, and a drain pipe 630 is fixed to the bottom of the cleaning tank 620. By setting up the cleaning mechanism, the stirring mechanism is transported to the cleaning mechanism location by the transport mechanism. The stirring mechanism is cleaned in all directions by the cleaning tank 620, and the sealing cover 230 is cleaned at the same time. At this time, the fermentation tank 210 is in an open state, which allows for convenient cleaning of the fermentation tank 210.
[0034] Working Principle: During operation, the fermentation tank is controlled via the control panel 110. Materials are injected into the fermentation tank body 210 through the feed pipe 240. The servo motor 320 drives the drive shaft 330 to rotate, which in turn drives the stirring frame 340 to rotate, thus stirring and fermenting the materials. During this process, the conveying mechanism presses the sealing cap 230 onto the top of the fermentation tank body 210. The hydraulic rod A420 moves the locking block 430, which engages with the edges of the fermentation tank body 210 and the sealing cap 230, securing them together. The sealing of the fermentation tank is ensured during stirring and fermentation. When the stirring mechanism needs to be cleaned, the locking mechanism releases the lock on the sealing cover 230. The hydraulic rod B540 drives the connecting bracket 550 to move upward, thereby moving the stirring mechanism. The drive motor 520 drives the lead screw 521 to rotate, and the rotation of the lead screw 521 drives the sliding seat 530 to move, thereby moving the stirring mechanism to the cleaning mechanism. The cleaning tank 620 cleans the stirring mechanism from all angles and cleans the sealing cover 230 at the same time. At this time, the fermentation tank 210 is in an open state, which allows for convenient cleaning of the fermentation tank 210.
[0035] The motor involved in the embodiments, its matching control system, electromagnetic switch and pipeline circuit can also be provided by the manufacturer. Apart from that, the power supply module, circuit and electronic components and control module involved in this utility model are all existing technologies, which can be fully implemented by those skilled in the art, and need not be elaborated. The content protected by this utility model does not involve any improvement to the internal structure and method.
[0036] Although the present invention discloses embodiments and accompanying drawings, those skilled in the art will understand that various substitutions, variations and modifications are possible without departing from the spirit and scope of the present invention and the appended claims. Therefore, the scope of the present invention is not limited to the contents disclosed in the embodiments and accompanying drawings.
Claims
1. A biopharmaceutical fermentation tank, characterized in that, The system includes a frame (100), the inner wall of which is fixed with a mounting ring (120) by bolts, the inner wall of which is fixed with a fermentation mechanism, the fermentation mechanism including a fermentation tank (210), the fermentation tank (210) being fixed with bolts to the inner wall of the mounting ring (120), the bottom of which is fixed with a discharge pipe (220), the top of which is provided with a sealing cover (230), the outside of which is fixed with a feed pipe (240), the top of which is provided with a stirring mechanism, the outside of which is provided with a locking mechanism, and the top of which is provided with a transport mechanism. The conveying mechanism includes a mounting slide (510), which is fixed to the top of the frame (100) by bolts. A drive motor (520) is fixed to one side of the mounting slide (510) by bolts. A lead screw (521) is provided at the output end of the drive motor (520). A sliding seat (530) is provided on the outside of the lead screw (521). A hydraulic rod B (540) is fixed to the top of the sliding seat (530). A connecting bracket (550) is fixed to the bottom of the hydraulic rod B (540). The connecting bracket (550) is fixedly connected to the sealing cover (230). A cleaning mechanism is provided on one side of the mounting ring (120).
2. The biopharmaceutical fermenter according to claim 1, characterized in that, A control panel (110) is provided on one side of the rack (100).
3. A biopharmaceutical fermenter according to claim 1, characterized in that, The stirring mechanism includes a motor mounting base (310), which is fixed to the top of the sealing cover (230) by bolts. A servo motor (320) is fixed to the top of the motor mounting base (310) by bolts. A drive shaft (330) is provided at the output end of the servo motor (320), and a stirring frame (340) is fixed to the bottom of the drive shaft (330).
4. A biopharmaceutical fermenter according to claim 1, characterized in that, The locking mechanism includes a mounting block (410), which is fixed to the outside of the fermentation tank (210) by bolts. A hydraulic rod A (420) is fixed to one side of the mounting block (410), and a locking block (430) is fixed to one end of the hydraulic rod A (420).
5. A biopharmaceutical fermenter according to claim 1, characterized in that, A limiting slider (531) is fixed on the outside of the sliding seat (530), and the limiting slider (531) is slidably connected to the mounting groove (510).
6. A biopharmaceutical fermenter according to claim 1, characterized in that, The cleaning mechanism includes a mounting bracket (610), which is fixed to the inner wall of the frame (100) by bolts. A cleaning tank (620) is fixed to the inner wall of the mounting bracket (610), and a drain pipe (630) is fixed to the bottom of the cleaning tank (620).