Drug stability testing device

Abstract

The utility model relates to a medicine stability testing device which comprises a device box body and a test box body, the test box body is installed on the side face of the device box body, a fixing rod is installed at the top end in the device box body, a water-gas dual-purpose pump is fixed to the bottom of the fixing rod, the side face of the water-gas dual-purpose pump is communicated with a first connecting pipe, and one end of the first connecting pipe is communicated with a vertical pipe. A vertical pipe is arranged in the device box body, the upper end and the lower end of the vertical pipe are of sealed structures, one end of the vertical pipe is communicated with a plurality of second connecting pipes, one ends of the plurality of second connecting pipes penetrate through the device box body and extend into the test box body, and a rotating test assembly is arranged in the test box body. Heat and cold air are uniformly conveyed into the test box body, so that the medicine can continuously rotate and is in full contact with the heat or the cold air at different positions, and the uniformity, the accuracy and the efficiency of the medicine stability test are improved.

Description

Technical Field

[0001] This utility model relates to the field of drug testing, specifically a drug stability testing device. Background Technology

[0002] Drug stability test chambers are used in the pharmaceutical, medical, and biotechnology industries, as well as all related research, including life sciences. Drug research and production require numerous tests, including high-temperature, low-temperature, and damp-heat tests. Drug stability test chambers primarily simulate temperature, humidity, and light exposure in environmental climates. They typically consist of a chamber, fluorescent lamps, a refrigeration compressor, a humidification device, a heating device, and various related sensors, providing a long-term stable temperature and humidity environment for drug storage and testing.

[0003] According to the published patent 202023210371.2, a drug stability testing device, it includes a test chamber, which is mounted on a box body. The test chamber contains several support plates, each with several placement slots. The side walls of the test chamber have sliding grooves. The support plates are slidably connected to the sliding grooves via sliders. The advantages of this invention compared to existing technologies are: the test chamber is protected by protective plates; shock-absorbing springs reduce vibrations; the placement plates can move up and down; drugs placed in the placement slots are less likely to slip; the water in the tank inside the chamber absorbs impurities from external gases and dries before entering the test chamber, resulting in good ventilation; fluorescent lamps, a heating chamber, a refrigeration device, and a humidifier facilitate the simulation of various environments; casters facilitate movement; and the fixing device allows for easy fixation when not in use.

[0004] In traditional drug stability testing equipment, drugs are placed in slots on multiple placement plates for stability testing. However, because the drug's position on the placement plates is fixed, and the distribution of hot and cold air within the test chamber is uneven, drugs in fixed positions are difficult to be heated or cooled evenly. Therefore, the temperature conditions experienced by drugs in different positions vary, affecting the accuracy of the drug stability test. Thus, a new technical solution is needed to address this issue. Utility Model Content

[0005] The purpose of this invention is to overcome the shortcomings of the existing technology, adapt to practical needs, and provide a drug stability testing device to solve the problem that in current traditional drug stability testing equipment, drugs are placed in placement slots of multiple placement plates for stability testing. However, since the position of the drug on the placement plate is fixed and the distribution of hot and cold air in the test chamber is uneven, it is difficult for drugs in fixed positions to be heated or cooled evenly. Therefore, the temperature conditions experienced by drugs in different positions are different, which affects the accuracy of drug stability testing.

[0006] To achieve the purpose of this utility model, the technical solution adopted by this utility model is as follows: a drug stability testing device is designed, including a device housing and a test chamber. The test chamber is installed on the side of the device housing. A fixing rod is installed at the top inside the device housing. A water-air dual-purpose pump is fixed at the bottom of the fixing rod. A first connecting pipe is connected to the side of the water-air dual-purpose pump. One end of the first connecting pipe is connected to a vertical pipe, and both ends of the vertical pipe are sealed. One end of the vertical pipe is connected to multiple second connecting pipes. One end of the multiple second connecting pipes passes through the device housing and extends into the test chamber. A rotating test assembly is set inside the test chamber.

[0007] Preferably, the rotation test assembly includes a bearing, a rotating rod, a fan, and a medicine placement tray.

[0008] Preferably, multiple bearings are respectively installed at the upper and lower ends inside the test chamber, and a rotating rod is rotatably connected between two bearings. Multiple impellers pass through the outside of the rotating rod, and the rotating rod and the impellers are fixedly connected at the through-point.

[0009] Preferably, the rotating rod has multiple medicine placement trays extending through its exterior, and the penetration position between the rotating rod and the medicine placement trays is fixed. The top of the medicine placement trays has a placement groove, and multiple partition plates are fixed in the placement groove.

[0010] Preferably, a water tank is installed at the bottom of the device housing, the top of the water tank has an open structure, and an ultrasonic atomizing plate is installed at the bottom of the water tank.

[0011] Preferably, a set of fixing blocks is installed on the top side of the device housing, the set of fixing blocks consists of two blocks, and an electric heating tube is fixed between the two fixing blocks. A refrigeration component is connected to the top of the device housing.

[0012] Preferably, the front end of the device housing has a mounting hole, a cover plate is installed inside the mounting hole, and a baffle is provided at the front end of the test housing, and the baffle is connected to the test housing by a hinge.

[0013] Compared with the prior art, the beneficial effects of this utility model are as follows:

[0014] 1. This utility model combines a water-air dual-purpose pump, an air outlet pipe, and a rotating test assembly. The water-air dual-purpose pump delivers generated heat and cold air into the test chamber for stability testing of the drugs inside. During the process of drawing heat and cold air into the test chamber, the air outlet of the second connecting pipe is located on the front side of the impeller. The blown gas drives multiple impellers to rotate, thereby rotating the drug placement tray and the drugs on it. This ensures that the drugs can fully contact the heat or cold air at different locations within the test chamber, effectively improving the uniformity and accuracy of the drug testing process. This solves the technical problem in traditional drug stability testing equipment where drugs are placed in slots on multiple placement plates for stability testing. However, because the positions of the drugs on the placement plates are fixed, and the distribution of heat and cold air within the test chamber is uneven, drugs in fixed positions are difficult to heat or cool evenly. Therefore, the temperature conditions experienced by drugs in different positions vary, affecting the accuracy of the drug stability test.

[0015] 2. This utility model combines a water tank, an ultrasonic atomizing plate, and a water-air dual-purpose pump. The ultrasonic atomizing plate is used to atomize the water in the water tank. Moreover, the water-air dual-purpose pump can directly draw the generated water mist into the test chamber to achieve humidification of the chamber. This eliminates the need for multiple additional conveying devices and simplifies the entire test system. Attached Figure Description

[0016] Figure 1 This is a schematic diagram of the overall structure of this utility model;

[0017] Figure 2 This is a schematic diagram of the internal structure of the device housing and test chamber of this utility model;

[0018] Figure 3 This is a top view of the structure of the medicine placement tray of this utility model.

[0019] In the diagram: 1. Device housing; 101. Mounting hole; 102. Cover plate; 2. Test chamber; 201. Baffle; 202. Fixing rod; 203. Water-air dual-purpose pump; 204. Divider plate; 205. First connecting pipe; 206. Vertical pipe; 207. Second connecting pipe; 208. Fan wheel; 209. Rotating rod; 210. Medicine placement tray; 211. Bearing; 212. Fixing block; 213. Heating element; 214. Placement slot; 3. Water tank; 301. Ultrasonic atomizing plate. Detailed Implementation

[0020] The present invention will be further described below with reference to the accompanying drawings and embodiments:

[0021] Example 1: A drug stability testing device, see [link to example]. Figures 1 to 3The device includes a housing 1 and a test chamber 2. The test chamber 2 is mounted on the side of the housing 1. A fixing rod 202 is mounted on the top of the inside of the housing 1. A water-air dual-purpose pump 203 is fixed to the bottom of the fixing rod 202. A first connecting pipe 205 is connected to the side of the water-air dual-purpose pump 203. One end of the first connecting pipe 205 is connected to a vertical pipe 206, and both ends of the vertical pipe 206 are sealed. One end of the vertical pipe 206 is connected to multiple second connecting pipes 207. One end of each of the multiple second connecting pipes 207 passes through the housing 1 and extends into the test chamber 2. A rotation test chamber is set up inside the test chamber 2. First, multiple medicines are placed into the placement slots 214 on the surface of multiple medicine placement trays 210. After placement, the cooling component or the heating element 213 can be selectively turned on according to the test requirements. When the cooling component is turned on, it will generate cold air, while when the heating element 213 is turned on, it will generate hot air. Then, the water-air dual-purpose pump 203 can simultaneously draw the generated heat and cold air into the test chamber 2. During the process of drawing the heat and cold air into the test chamber 2, they are transported to the front side of the impeller 208 through the second connecting pipe 207. The air outlet of the second connecting pipe 207 is located at the front side of the impeller 208. The air blown out from the front of the impeller 208 (whether hot or cold) can directly act on the impeller 208, driving multiple impellers 208 to rotate. When the impeller 208 rotates, it will drive the rotating rod 209 connected to it to rotate as well. The rotating rod 209 is connected to the medicine placement tray 210 through the bearing 211. Therefore, when the rotating rod 209 rotates, it will drive the medicine placement tray 210 and the medicine on it to rotate together, ensuring that the medicine can continuously change position in the test chamber 2 and fully contact the heat or cold air in different positions, regardless of the distribution of the heat or cold air in the chamber. The drug can be heated or cooled uniformly, thus effectively improving the uniformity and accuracy of the drug testing process. This solves the technical problem in traditional drug stability testing equipment where the drug is placed in the placement slot 214 of multiple placement plates for stability testing. However, since the position of the drug on the placement plate is fixed and the distribution of hot and cold air in the test chamber 2 is uneven, the drug in the fixed position is difficult to be heated or cooled uniformly. Therefore, the temperature conditions of the drug in different positions are different, which affects the accuracy of the drug stability test.

[0022] For details, see Figure 2 The rotation test assembly includes a bearing 211, a rotating rod 209, a fan wheel 208, and a medicine placement tray 210.

[0023] Further, see Figure 2 Multiple bearings 211 are respectively installed at the upper and lower ends inside the test chamber 2, and a rotating rod 209 is rotatably connected between two bearings 211. Multiple impellers 208 pass through the outside of the rotating rod 209, and the rotating rod 209 and the impellers 208 are fixedly connected at the through position.

[0024] It is worth noting that, see Figure 2 and Figure 3 Multiple medicine placement trays 210 are passed through the outside of the rotating rod 209, and the position of the rotating rod 209 through the medicine placement trays 210 is fixed. A placement groove 214 is opened on the top of the medicine placement tray 210, and multiple partition plates 204 are fixed in the placement groove 214.

[0025] It is worth noting that, see Figure 2 The bottom of the device housing 1 is equipped with a water tank 3. The top of the water tank 3 is an open structure. An ultrasonic atomizing plate 301 is installed at the bottom of the water tank 3. When it is necessary to humidify the inside of the test chamber 2, the ultrasonic atomizing plate 301 is turned on first. The ultrasonic atomizing plate 301 uses high-frequency vibration to atomize the water molecules in the water tank 3 into tiny water mist particles. Then, the water-air dual-purpose pump 203 is started. The water-air dual-purpose pump 203 is a multi-functional pump that can process gas and liquid at the same time. After the water mist is drawn by the water-air dual-purpose pump 203, it is transported to the vertical pipe 206 through the first connecting pipe 205. The vertical pipe 206 serves as an intermediate link connecting the first connecting pipe 205 and multiple second connecting pipes 207, and plays the role of guiding and distributing the water mist. Then, the water mist enters the multiple second connecting pipes 207 through the vertical pipe 206. Finally, the water mist is directly delivered into the test chamber 2 through the second connecting pipe 207. Inside the test chamber 2, the water mist spreads rapidly, increasing the humidity inside the chamber and realizing the humidification function inside the chamber.

[0026] It is worth mentioning that, see Figure 2 A set of fixing blocks 212 is installed on the top side of the device housing 1. There are two fixing blocks 212, and an electric heating tube 213 is fixed between the two fixing blocks 212. A refrigeration component is connected to the top of the device housing 1.

[0027] It is worth emphasizing that, see Figure 1 The front end of the device housing 1 has a mounting hole 101, and a cover plate 102 is installed inside the mounting hole 101. The front end of the test housing 2 is provided with a baffle 201, and the baffle 201 is connected to the test housing 2 by a hinge.

[0028] It should be noted that when the water-air dual-purpose pump 203 delivers the generated heat or cold air to the front side of the impeller 208 through the second connecting pipe 207, the airflow impacts the blades of the impeller 208 at a certain speed and pressure. Under the continuous action of the airflow, the impeller 208 begins to rotate, thereby transmitting the rotational torque to the rotating rod 209, which drives the multiple medicine placement trays 210 to rotate.

[0029] To ensure that the gas extracted by the water-gas dual-purpose pump 203 has sufficient pressure to effectively drive the wind turbine 208 to rotate, a booster pump can be configured between the water-gas dual-purpose pump 203 and the second pipeline. The booster pump increases the pressure of the gas, thereby ensuring that the airflow can fully drive the wind turbine 208 to rotate.

[0030] The refrigeration components involved in this application include a compressor, a condenser, a dryer, and an evaporator. These components are all existing technologies in the refrigeration field, so their specific structures and working principles are not described in detail in this application.

[0031] The heating element 213 and the cooling components are connected to a temperature controller to achieve temperature control, so as to accurately adjust and maintain the required working temperature. At the same time, the test chamber 2 is equipped with a temperature and humidity sensor, which is responsible for real-time monitoring and feedback of the temperature and humidity inside the chamber.

[0032] When using a drug stability testing device, firstly, multiple drugs are placed into the placement slots 214 on the surface of multiple drug placement trays 210. After placement, depending on the test requirements, the cooling component or the heating element 213 can be selectively turned on. When the cooling component is turned on, it generates cold air, while when the heating element 213 is turned on, it generates hot air. Then, the water-air dual-purpose pump 203 can simultaneously draw the generated heat and cold air into the test chamber 2. During the process of drawing heat and cold air into the test chamber 2, they are transported to the front side of the impeller 208 through the second connecting pipe 207. The air outlet of the second connecting pipe 207 is located on the front side of the impeller 208, and the blown air (whether hot or cold) can directly act on the impeller 208, driving multiple impellers 208 to start rotating. When the impeller 208 rotates, it will drive the rotating rod 209 connected to it to rotate as well. The rotating rod 209 is connected to the drug placement tray 210 through the bearing 211. Therefore, when the rotating rod 209 rotates, it will drive the impeller 208 to rotate. The rotating drug placement tray 210 and the drugs on it ensure that the drugs can continuously change position within the test chamber 2, making full contact with heat or cold air at different locations. Regardless of the distribution of heat or cold air within the chamber, the drugs can be uniformly heated or cooled, thereby effectively improving the uniformity and accuracy of the drug testing process. When humidification is required inside the test chamber 2, the ultrasonic atomizing plate 301 is first turned on. The ultrasonic atomizing plate 301 uses high-frequency vibration to atomize water molecules in the water tank 3 into tiny water mist particles. Then, the water-air dual-purpose pump 203 is started. The water-air dual-purpose pump 203 is a multi-functional pump that can handle both gas and liquid simultaneously. After the water mist is drawn by the water-air dual-purpose pump 203, it is transported to the vertical pipe 206 through the first connecting pipe 205. The vertical pipe 206, as an intermediate link connecting the first connecting pipe 205 and multiple second connecting pipes 207, plays a role in guiding and distributing the water mist. Then, the water mist enters the multiple second connecting pipes 207 through the vertical pipe 206. Finally, the water mist is directly delivered into the test chamber 2 through the second connecting pipe 207. Inside the test chamber 2, the water mist spreads rapidly, increasing the humidity inside the chamber and realizing the humidification function inside the chamber.

[0033] In addition, all components designed in this utility model are general standard parts or components known to those skilled in the art. Their structure and principle can be learned by those skilled in the art through technical manuals or conventional experimental methods. Those skilled in the art can fully implement them, so there is no need to elaborate. The content protected by this utility model does not involve improvements to the internal structure and method.

[0034] The embodiments disclosed herein are preferred embodiments, but are not limited thereto. Those skilled in the art can readily grasp the spirit of this utility model based on the above embodiments and make different extensions and variations. However, as long as they do not depart from the spirit of this utility model, they are all within the protection scope of this utility model.

Claims

1. A pharmaceutical stability testing device comprising a device case (1) and a test case (2), the test case (2) being attached to the side of the device case (1), characterized in that, A fixing rod (202) is installed at the top of the device housing (1). A water-air dual-purpose pump (203) is fixed at the bottom of the fixing rod (202). A first connecting pipe (205) is connected to the side of the water-air dual-purpose pump (203). One end of the first connecting pipe (205) is connected to a vertical pipe (206). Both ends of the vertical pipe (206) are sealed. One end of the vertical pipe (206) is connected to multiple second connecting pipes (207). One end of the multiple second connecting pipes (207) passes through the device housing (1) and extends into the test chamber (2). A rotating test assembly is installed inside the test chamber (2).

2. The drug stability testing apparatus as described in claim 1, characterized in that, The rotation test assembly includes a bearing (211), a rotating rod (209), a fan (208), and a medicine placement tray (210).

3. The pharmaceutical stability test device of claim 2, wherein Multiple bearings (211) are respectively installed at the upper and lower ends inside the test chamber (2), and a rotating rod (209) is rotatably connected between two bearings (211). Multiple impellers (208) pass through the outside of the rotating rod (209), and the rotating rod (209) and the impellers (208) are fixedly connected at the through position.

4. The pharmaceutical stability test device of claim 2, wherein Multiple medicine placement trays (210) are passed through the outside of the rotating rod (209), and the position of the rotating rod (209) and the medicine placement trays (210) is fixed. A placement groove (214) is opened on the top of the medicine placement tray (210), and multiple partition plates (204) are fixed in the placement groove (214).

5. The pharmaceutical stability test device of claim 1, wherein The device housing (1) has a water tank (3) installed at the bottom inside. The top of the water tank (3) is an open structure. An ultrasonic atomizing plate (301) is installed at the bottom inside the water tank (3).

6. The pharmaceutical stability test apparatus according to claim 1, wherein A set of fixing blocks (212) is installed on the top side of the device housing (1). There are two fixing blocks (212), and an electric heating tube (213) is fixed between the two fixing blocks (212). A refrigeration component is connected to the top of the device housing (1).

7. The pharmaceutical stability test device of claim 1, wherein The device housing (1) has a mounting hole (101) at the front end, and a cover plate (102) is installed inside the mounting hole (101). The test housing (2) has a baffle (201) at the front end, and the baffle (201) is connected to the test housing (2) by a hinge.

Images