Non-natural amino acid biological fermentation device
By combining temperature control, stirring, gas supply and exhaust mechanisms, the problems of small gas-liquid contact area and temperature and pressure control in amino acid bio-fermentation devices are solved, and a highly efficient fermentation process is achieved.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- GAOTANG AOHAN BIOTECHNOLOGY CO LTD
- Filing Date
- 2025-05-22
- Publication Date
- 2026-05-01
AI Technical Summary
Existing amino acid bio-fermentation devices have small gas-liquid contact areas and low mass transfer efficiency, making it difficult to meet the dissolved oxygen requirements of the fermentation process. Furthermore, it is difficult to control temperature and pressure in a timely manner, which affects the fermentation effect.
The combined design of temperature control, stirring, gas supply and exhaust mechanisms increases the contact area between oxygen and solution, enabling temperature and pressure regulation and ensuring stable fermentation.
By increasing the contact area between oxygen and the solution and by timely adjusting the temperature and pressure, fermentation efficiency was improved, adverse effects during the fermentation process were avoided, and the fermentation effect was ensured.
Smart Images
Figure CN224186155U_ABST
Abstract
Description
A non-natural amino acid bio-fermentation device Technical Field
[0001] This utility model relates to the technical field of chemical equipment, and in particular to a non-natural amino acid bio-fermentation device. Background Technology
[0002] Amino acid fermentation is a process that requires oxygen. Currently, all known amino acid-producing bacteria are aerobic bacteria, meaning that an adequate amount of sterile air must be supplied for the bacteria to reproduce and accumulate the necessary metabolic products. Therefore, how to supply oxygen rationally and efficiently has become an indispensable part of amino acid production.
[0003] Existing amino acid bio-fermentation devices, such as the amino acid bio-fermenter disclosed in utility model patent application number 202421242569.4, mainly include a bio-fermenter and an upper-mounted drive motor. A tension steel wire rope is connected to the side of a central connecting column. A connecting support outer column is located on the side of the motor connecting shaft column. A compression connecting spring is located inside the connecting support outer column, and a connecting insertion inner column is located at the end of the compression connecting spring. In use, rotating the adjusting knob raises or lowers the connecting threaded column, which can stretch or release the tension steel wire rope to adjust the distance between the agitator body and the inner wall of the bio-fermenter, allowing the amino acid bio-fermenter to adjust the stirring according to different fermentation processes.
[0004] However, most existing fermentation devices have small gas-liquid contact areas and low mass transfer efficiency, making it difficult to meet the dissolved oxygen requirements of the entire fermentation process. Moreover, in the non-natural amino acid bio-fermentation process, the temperature and pressure inside the tank will rise, and existing fermentation devices cannot adjust the temperature and pressure inside the tank in a timely manner, which can easily affect the fermentation effect. Summary of the Invention
[0005] To solve the above-mentioned technical problems, this utility model provides a non-natural amino acid bio-fermentation device that not only increases the contact area between oxygen and solution, making it easier to meet the dissolved oxygen requirements of the entire fermentation process, but also allows for timely regulation of temperature and air pressure to avoid affecting the fermentation effect.
[0006] This utility model discloses a non-natural amino acid bio-fermentation device, comprising a fermentation tank; it also includes a temperature control mechanism, a stirring mechanism, a gas supply mechanism, and an exhaust mechanism. The temperature control mechanism is installed on the fermentation tank to maintain a constant internal temperature. The stirring mechanism is installed on the temperature control mechanism to stir the solution. The gas supply mechanism is installed on the temperature control mechanism to deliver sterile oxygen into the fermentation tank. The exhaust mechanism is installed on the gas supply mechanism to facilitate pressure relief. The operator delivers the fermentation liquid into the fermentation tank. The temperature control mechanism regulates the temperature of the fermentation tank. The stirring mechanism stirs the solution to accelerate amino acid fermentation. Simultaneously, the gas supply mechanism evenly delivers sterile oxygen into the solution to ensure adequate oxygen supply. The gas generated during fermentation is discharged through the exhaust mechanism.
[0007] Preferably, the fermentation tank includes a tank body, a feeding pipe, a first valve, a discharge pipe, and a discharge valve. The bottom end of the tank body is connected to the ground, and the tank body has an internal cavity. The bottom end of the feeding pipe is connected to the top end of the tank body. The first valve is installed on the feeding pipe, the top end of the discharge pipe is connected to the bottom end of the tank body, and the discharge valve is installed on the discharge pipe. After the feeding equipment is connected to the feeding pipe, the first valve is opened, and the solution is delivered into the cavity of the tank body. When the amino acid fermentation is completed, the discharge valve is opened, and the solution is discharged through the discharge pipe.
[0008] Preferably, the temperature control mechanism includes an insulation layer, an inlet pipe, a drain pipe, two sets of second valves, and a first thermometer. The insulation layer wraps around the outside of the tank body, forming a sandwich between the insulation layer and the tank body. The inlet pipe is installed on the insulation layer and communicates with the inside of the sandwich. The drain pipe is installed on the insulation layer and communicates with the inside of the sandwich. The two sets of second valves are respectively installed on the inlet pipe and the drain pipe. The first thermometer is installed on the insulation layer. Hot water is transported into the sandwich through the inlet pipe. The insulation layer keeps the hot water warm. The first thermometer detects the water temperature to ensure that the cavity of the tank maintains a suitable temperature. When the temperature drops, the two sets of second valves are opened, and the cold water is discharged through the drain pipe. The hot water is then transported back into the sandwich through the inlet pipe.
[0009] Preferably, the stirring mechanism includes a motor, a reducer, a drive shaft, a triangular bracket, multiple sets of fan blades, and a second thermometer. The bottom end of the motor is connected to the top end of the tank, and the bottom end of the reducer is also connected to the top end of the tank. The drive shaft is rotatably installed in the cavity of the tank and longitudinally connected to the reducer. The triangular bracket is installed in the cavity of the tank, and multiple sets of fan blades are all installed on the drive shaft. The second thermometer is installed on the triangular bracket. The second thermometer detects the temperature of the solution in the cavity, facilitating timely replacement of the hot water in the jacket. The motor is started, and the motor drives the drive shaft to rotate through the reducer. The drive shaft drives the multiple sets of fan blades to rotate, stirring the solution.
[0010] Preferably, multiple sets of fan blades are also installed at an angle on the drive shaft; the angled installation can not only break the laminar boundary layer and increase the turbulence intensity, but also promote the uniform dispersion of bacteria and substrate, accelerate the transfer of dissolved oxygen, make the heat evenly distributed, and avoid local overheating.
[0011] Preferably, the gas supply mechanism includes a gas supply pipe, a heat exchange pipe, multiple sets of gas delivery branch pipes, and multiple sets of aeration heads. The gas supply pipe is installed on the insulation layer and communicates with the interior of the oxygen supply equipment. The heat exchange pipe is installed in the interlayer and communicates with the interior of the gas supply pipe. The multiple sets of gas delivery branch pipes are all installed in the cavity of the tank and communicate with the interior of the heat exchange pipe. The multiple sets of aeration heads are respectively installed on the multiple sets of gas delivery branch pipes. The oxygen supply equipment delivers sterile oxygen to the heat exchange pipe through the gas supply pipe. Hot water heats the sterile oxygen through the heat exchange pipe. The heated sterile oxygen is delivered to the multiple sets of aeration heads through the multiple sets of gas delivery branch pipes. The multiple sets of aeration heads diffuse the sterile oxygen into the solution, increasing the contact area between oxygen and solution and ensuring the dissolved oxygen content.
[0012] Preferably, the exhaust mechanism includes an exhaust pipe, an oxygen content detector, a pressure relief valve, a return pipe, a third valve, and a check valve. The bottom end of the exhaust pipe is connected to the top of the tank. The oxygen content detector is installed on the exhaust pipe, the pressure relief valve is installed on the exhaust pipe, the return pipe is installed on the exhaust pipe and connected to the inside of the heat exchange tube, the third valve is installed on the return pipe, and the check valve is installed on the return pipe. When the air pressure inside the tank cavity is too high, air enters the exhaust pipe. The oxygen content detector detects the oxygen content in the air. When a high oxygen content is detected, the third valve is opened, and the air flows back to the heat exchange tube through the return pipe. The check valve prevents air from the heat exchange tube from entering the return pipe. When a low oxygen content is detected, the pressure relief valve automatically releases pressure and exhausts the air.
[0013] Compared with the prior art, the beneficial effects of this utility model are as follows: the staff delivers the fermentation liquid into the fermentation tank, the temperature control mechanism regulates the temperature of the fermentation tank, the stirring mechanism stirs the solution to accelerate the fermentation of amino acids, and at the same time the gas supply mechanism delivers sterile oxygen evenly into the solution to ensure the oxygen supply. The gas generated during the fermentation process is discharged through the exhaust mechanism. Attached Figure Description
[0014] Figure 1 is a front sectional view of the present invention.
[0015] Figure 2 is a front view structural diagram of the fermenter of this utility model;
[0016] Figure 3 is an isometric structural diagram of the temperature control mechanism and stirring mechanism of this utility model;
[0017] Figure 4 is a front view cross-sectional structural schematic diagram of the stirring mechanism and the gas supply mechanism of this utility model;
[0018] Figure 5 is a partially enlarged isometric structural diagram of the exhaust mechanism of this utility model.
[0019] The attached diagram is labeled as follows: 01, Fermentation tank; 11, Tank body; 12, Feeding pipe; 13, First valve; 14, Discharge pipe; 15, Discharge valve; 02, Temperature control mechanism; 21, Insulation layer; 22, Water inlet pipe; 23, Drain pipe; 24, Second valve; 25, First thermometer; 03, Stirring mechanism; 31, Electric motor; 32, Reducer; 33, Drive shaft; 34, Triangular bracket; 35, Fan blade; 36, Second thermometer; 04, Gas supply mechanism; 41, Gas supply pipe; 42, Heat exchange pipe; 43, Gas supply branch pipe; 44, Aeration head; 05, Exhaust mechanism; 51, Exhaust pipe; 52, Oxygen content detector; 53, Pressure relief valve; 54, Return pipe; 55, Third valve; 56, Check valve. Detailed Implementation
[0020] To facilitate understanding of this utility model, a more complete description will be given below with reference to the accompanying drawings. This utility model can be implemented in many different forms and is not limited to the embodiments described herein. Rather, these embodiments are provided to make the disclosure of this utility model more thorough and complete.
[0021] Example 1
[0022] This utility model discloses a non-natural amino acid bio-fermentation device, comprising a fermentation tank 01; it also includes a temperature control mechanism 02, a stirring mechanism 03, a gas supply mechanism 04, and an exhaust mechanism 05. The temperature control mechanism 02 is installed on the fermentation tank 01 and maintains a constant internal temperature. The stirring mechanism 03 is installed on the temperature control mechanism 02 and stirs the solution. The gas supply mechanism 04 is installed on the temperature control mechanism 02 and delivers sterile oxygen into the fermentation tank 01. The exhaust mechanism 05 is installed on the gas supply mechanism 04 and facilitates pressure relief. The fermentation tank 01 includes a tank body 11, a feeding pipe 12, a first valve 13, a discharge pipe 14, and a discharge valve 15. The bottom end of the tank body 11 is connected to the ground, and the interior of the tank body 11 has a cavity. The bottom end of the feeding pipe 12 is connected to the top end of the tank body 11. The internal structure is interconnected. A first valve 13 is installed on the feeding pipe 12, and the top of the discharge pipe 14 is internally connected to the bottom of the tank body 11. A discharge valve 15 is installed on the discharge pipe 14. The temperature control mechanism 02 includes an insulation layer 21, a water inlet pipe 22, a drain pipe 23, two sets of second valves 24, and a first thermometer 25. The insulation layer 21 wraps around the outside of the tank body 11, forming a sandwich between the insulation layer 21 and the tank body 11. The water inlet pipe 22 is installed on the insulation layer 21 and communicates with the inside of the sandwich. The drain pipe 23 is installed on the insulation layer 21 and communicates with the inside of the sandwich. Two sets of second valves 24 are respectively installed on the water inlet pipe 22 and the drain pipe 23. The first thermometer 25 is installed on the insulation layer 21. The stirring mechanism 03 includes a motor 31, a reducer 32, a drive shaft 33, and a triangular... The system includes a support bracket 34, multiple sets of fan blades 35, and a second thermometer 36. The bottom end of a motor 31 is connected to the top end of the tank 11, and the bottom end of a reducer 32 is also connected to the top end of the tank 11. A drive shaft 33 is rotatably mounted inside the cavity of the tank 11 and longitudinally connected to the reducer 32. A triangular support bracket 34 is installed inside the cavity of the tank 11. Multiple sets of fan blades 35 are mounted on the drive shaft 33, and the second thermometer 36 is mounted on the triangular support bracket 34. The system also includes multiple sets of fan blades 35 mounted at an angle on the drive shaft 33. During operation, firstly, after the feeding equipment is connected to the feeding pipe 12, the first valve 13 is opened, and the solution is delivered into the cavity of the tank 11. Hot water is delivered to the jacket through the water inlet pipe 22. The insulation layer 21 insulates the hot water, and the first thermometer 25 monitors the water temperature. The system is tested to ensure that the cavity of tank 11 maintains a suitable temperature. When the temperature drops, the two sets of second valves 24 are opened, and the cold water is discharged through the drain pipe 23. The hot water is then transported back into the jacket through the inlet pipe 22. The second thermometer 36 detects the temperature of the solution in the cavity to facilitate timely replacement of the hot water in the jacket. The motor 31 is started, and the motor 31 drives the drive shaft 33 to rotate through the reducer 32. The drive shaft 33 drives multiple sets of fan blades 35 to rotate and stir the solution. The inclined installation can not only break the laminar boundary layer and increase the turbulence intensity, but also promote the uniform dispersion of bacteria and substrate, accelerate the transfer of dissolved oxygen, and make the heat evenly distributed to avoid local overheating. When the amino acid fermentation is completed, the discharge valve 15 is opened, and the solution is discharged through the discharge pipe 14.
[0023] Example 2
[0024] As shown in Figures 1 to 5, this utility model discloses a non-natural amino acid bio-fermentation device based on Example 1. The gas supply mechanism 04 includes a gas supply pipe 41, a heat exchange pipe 42, multiple sets of gas supply branch pipes 43, and multiple sets of aeration heads 44. The gas supply pipe 41 is installed on the insulation layer 21 and communicates with the interior of the oxygen supply equipment. The heat exchange pipe 42 is installed in the interlayer and communicates with the interior of the gas supply pipe 41. The multiple sets of gas supply branch pipes 43 are all installed in the cavity of the tank body 11 and communicate with the interior of the heat exchange pipe 42. The multiple sets of aeration heads 44 are respectively installed on the multiple sets of gas supply branch pipes 43. The exhaust mechanism 05 includes an exhaust pipe 51, an oxygen content detector 52, a pressure relief valve 53, a return pipe 54, a third valve 55, and a check valve 56. The bottom of the 1 is connected to the top of the tank 11. The oxygen content detector 52 is installed on the exhaust pipe 51, the pressure relief valve 53 is installed on the exhaust pipe 51, the return pipe 54 is installed on the exhaust pipe 51 and connected to the heat exchange pipe 42, the third valve 55 is installed on the return pipe 54, and the check valve 56 is installed on the return pipe 54. When it is working, firstly, after the feeding equipment is connected to the feeding pipe 12, the first valve 13 is opened, and the solution is transported into the cavity of the tank 11. Hot water is transported into the jacket through the water inlet pipe 22. The insulation layer 21 keeps the hot water warm. The first thermometer 25 detects the water temperature to ensure that the cavity of the tank 11 maintains a suitable temperature. When the temperature drops, the two sets of second valves 24 are opened. Cold water is discharged through drain pipe 23, and hot water is reintroduced into the jacket through inlet pipe 22. A second thermometer 36 monitors the solution temperature within the cavity, facilitating timely replacement of the hot water in the jacket. Motor 31 is started, and it drives transmission shaft 33 to rotate via reducer 32. Transmission shaft 33 drives multiple sets of fan blades 35 to rotate and stir the solution. The inclined installation not only breaks the laminar boundary layer and increases turbulence intensity but also promotes uniform dispersion of bacteria and substrate, accelerates dissolved oxygen transfer, and ensures even heat distribution, preventing localized overheating. The oxygen supply equipment delivers sterile oxygen through supply pipe 41 to heat exchange pipe 42. Hot water heats the sterile oxygen through heat exchange pipe 42. The heated sterile oxygen... Oxygen is delivered to multiple aeration heads 44 through multiple sets of air supply branches 43. The multiple aeration heads 44 diffuse sterile oxygen into the solution, increasing the contact area between oxygen and solution and ensuring dissolved oxygen content. When the air pressure in the cavity of tank 11 is too high, air enters the exhaust pipe 51. The oxygen content detector 52 detects the oxygen content in the air. When the oxygen content is detected to be high, the third valve 55 is opened, and the air flows back to the heat exchange tube 42 through the return pipe 54. A check valve 56 is set to prevent air in the heat exchange tube 42 from entering the return pipe 54. When the oxygen content is detected to be low, the pressure relief valve 53 automatically releases pressure and exhausts air. When the amino acid fermentation is completed, the discharge valve 15 is opened, and the solution is discharged through the discharge pipe 14.
[0025] The electric motor 31 and the reducer 32 of this utility model are commercially available. Technical personnel in this industry only need to install and operate them according to the accompanying instruction manual, without requiring any creative work from those skilled in the art.
[0026] The above description is only a preferred embodiment of the present utility model. It should be noted that for those skilled in the art, several improvements and modifications can be made without departing from the technical principles of the present utility model, and these improvements and modifications should also be considered within the protection scope of the present utility model.
Claims
1. A non-natural amino acid bio-fermentation device, comprising a fermenter (01); characterized in that, It also includes a temperature control mechanism (02), a stirring mechanism (03), a gas supply mechanism (04), and an exhaust mechanism (05). The temperature control mechanism (02) is installed on the fermenter (01) and keeps the internal temperature of the fermenter (01) constant. The stirring mechanism (03) is installed on the temperature control mechanism (02) and stirs the solution. The gas supply mechanism (04) is installed on the temperature control mechanism (02) and delivers sterile oxygen to the fermenter (01). The exhaust mechanism (05) is installed on the gas supply mechanism (04) and facilitates pressure relief.
2. The non-natural amino acid bio-fermentation device as described in claim 1, characterized in that, The fermentation tank (01) includes a tank body (11), a feeding pipe (12), a first valve (13), a discharge pipe (14), and a discharge valve (15). The bottom end of the tank body (11) is connected to the ground. The tank body (11) has a cavity inside. The bottom end of the feeding pipe (12) is connected to the top end of the tank body (11). The first valve (13) is installed on the feeding pipe (12). The top end of the discharge pipe (14) is connected to the bottom end of the tank body (11). The discharge valve (15) is installed on the discharge pipe (14).
3. The non-natural amino acid bio-fermentation device as described in claim 2, characterized in that, The temperature control mechanism (02) includes an insulation layer (21), an inlet pipe (22), a drain pipe (23), two sets of second valves (24) and a first thermometer (25). The insulation layer (21) is wrapped around the outside of the tank body (11), and a sandwich is formed between the insulation layer (21) and the tank body (11). The inlet pipe (22) is installed on the insulation layer (21) and communicates with the inside of the sandwich. The drain pipe (23) is installed on the insulation layer (21) and communicates with the inside of the sandwich. The two sets of second valves (24) are installed on the inlet pipe (22) and the drain pipe (23) respectively. The first thermometer (25) is installed on the insulation layer (21).
4. The non-natural amino acid bio-fermentation device as described in claim 2, characterized in that, The stirring mechanism (03) includes a motor (31), a reducer (32), a drive shaft (33), a triangular bracket (34), multiple sets of fan blades (35), and a second thermometer (36). The bottom end of the motor (31) is connected to the top end of the tank (11), the bottom end of the reducer (32) is connected to the top end of the tank (11), the drive shaft (33) is rotatably installed in the cavity of the tank (11) and longitudinally connected to the reducer (32), the triangular bracket (34) is installed in the cavity of the tank (11), the multiple sets of fan blades (35) are all installed on the drive shaft (33), and the second thermometer (36) is installed on the triangular bracket (34).
5. The non-natural amino acid bio-fermentation device as described in claim 4, characterized in that, It also includes multiple sets of fan blades (35) that are all mounted at an angle on the drive shaft (33).
6. The non-natural amino acid bio-fermentation device as described in claim 3, characterized in that, The gas supply mechanism (04) includes a gas supply pipe (41), a heat exchange pipe (42), multiple sets of gas supply branch pipes (43) and multiple sets of aeration heads (44). The gas supply pipe (41) is installed on the insulation layer (21) and connected to the inside of the oxygen supply equipment. The heat exchange pipe (42) is installed in the interlayer and connected to the inside of the gas supply pipe (41). The multiple sets of gas supply branch pipes (43) are all installed in the cavity of the tank (11) and connected to the inside of the heat exchange pipe (42). The multiple sets of aeration heads (44) are respectively installed on the multiple sets of gas supply branch pipes (43).
7. The non-natural amino acid bio-fermentation device as described in claim 6, characterized in that, The exhaust mechanism (05) includes an exhaust pipe (51), an oxygen content detector (52), a pressure relief valve (53), a return pipe (54), a third valve (55), and a check valve (56). The bottom end of the exhaust pipe (51) is connected to the inside of the top of the tank (11). The oxygen content detector (52) is installed on the exhaust pipe (51). The pressure relief valve (53) is installed on the exhaust pipe (51). The return pipe (54) is installed on the exhaust pipe (51) and is connected to the inside of the heat exchange tube (42). The third valve (55) is installed on the return pipe (54). The check valve (56) is installed on the return pipe (54).
Citation Information
Patent Citations
Amino acid biological fermentation tank
CN222540756U