Fermentation liquid extraction equipment

Abstract

The utility model relates to fermentation liquor extraction equipment. Comprising a solid-liquid separation device and a fermentation liquor extraction device. The solid-liquid separation device is provided with a discharge hole; the fermentation liquor extraction device comprises a fermentation container and an ultrasonic generator, the fermentation container is provided with a containing cavity, an inlet and an outlet, the inlet and the outlet are communicated with the containing cavity, the inlet is communicated with the discharge port, and the ultrasonic generator is arranged on the fermentation container. Fermentation liquid separated by the solid-liquid separation device enters the containing cavity from the inlet of the fermentation container, the ultrasonic generator generates ultrasonic waves which directly act on the fermentation liquid in the containing cavity, release of target components from thalli to a solvent is accelerated, loss of the components of the fermentation liquid is reduced, and the extraction time is shortened. A discharge hole of the solid-liquid separation device is directly communicated with an inlet of the fermentation container, so that a separation-extraction integrated continuous process is formed, the loss of an intermediate link is reduced, and the production efficiency is improved. Based on the scheme, the fermentation liquor extraction equipment can reduce the component loss of the fermentation liquor, improve the extraction efficiency and realize rapid and efficient extraction.

Description

Fermentation broth extraction equipment Technical Field

[0001] This application relates to the field of bio-fermentation technology, and in particular to a fermentation broth extraction device. Background Technology

[0002] In modern industrial production, fermentation broth extraction technology has extremely important applications in many fields such as food, pharmaceuticals, and chemicals. For example, in the food industry, fermentation broth extraction technology is used to produce various seasonings and beverages; in the pharmaceutical industry, it is used to extract drug components such as antibiotics, amino acids, and vitamins; and in the chemical industry, it is used to produce chemical products such as organic acids and enzyme preparations. With the increasing market demand for fermented products and the continuous improvement of requirements for product quality and production efficiency, developing efficient and precise fermentation broth extraction equipment suitable for industrial production has become crucial for the industry's development. Current fermentation broth extraction equipment suffers from low extraction efficiency and significant loss of fermentation broth components, making it difficult to achieve rapid and efficient extraction.

[0003] The information disclosed in this background section is intended only to enhance the understanding of the overall background of this utility model and should not be construed as an admission or in any way implying that the information constitutes prior art known to those skilled in the art. Summary of the Invention

[0004] Therefore, it is necessary to provide a fermentation broth extraction device to address the problems of low extraction efficiency, significant loss of fermentation broth components, and difficulty in achieving rapid and efficient extraction in current fermentation broth extraction devices.

[0005] A fermentation broth extraction device, comprising:

[0006] A solid-liquid separation device, wherein the solid-liquid separation device is provided with a discharge port;

[0007] A fermentation broth extraction device includes a fermentation container and an ultrasonic generator. The fermentation container has a receiving cavity and an inlet and an outlet communicating with the receiving cavity. The inlet is connected to the discharge port. The ultrasonic generator is located on the fermentation container.

[0008] In one embodiment, the fermentation container is further provided with an air inlet, which is connected to the containment cavity. The fermentation broth extraction device further includes a gas conveying device located outside the fermentation container, with the gas outlet of the gas conveying device connected to the air inlet.

[0009] In one embodiment, the gas delivery device includes an air compressor, the air compressor’s outlet being connected to the air inlet.

[0010] In one embodiment, the fermentation broth extraction device further includes a temperature control device located outside the fermentation container, which is used to control the temperature of the fermentation container.

[0011] In one embodiment, the temperature control device includes a liquid circulator and a heat exchanger. The heat exchanger is located outside the fermentation vessel. The liquid circulator has a first inlet and a first outlet. The heat exchanger has a liquid storage chamber and a second inlet and a second outlet communicating with the liquid storage chamber. The second inlet is connected to the first outlet, and the second outlet is connected to the first inlet, so as to form a fluid circulation path between the liquid circulator and the heat exchanger.

[0012] In one embodiment, the liquid circulator includes a water bath and a pump body. The water bath is provided with a first liquid inlet and a first liquid outlet, and the pump body is provided with a third liquid inlet and a third liquid outlet. The third liquid inlet is connected to the first liquid outlet, and the third liquid outlet is connected to the second liquid inlet.

[0013] In one embodiment, the temperature control device further includes a temperature sensor disposed within the containment cavity of the fermentation vessel.

[0014] In one embodiment, the fermentation broth extraction device further includes a stirrer, which includes a stirring motor and a stirring paddle. The main body of the stirring motor is located outside the receiving cavity, while the output end of the stirring motor and the stirring paddle are both located inside the receiving cavity. The output end of the stirring motor is driven and connected to the stirring paddle.

[0015] In one embodiment, the solid-liquid separation device includes a filter press having the discharge port.

[0016] In one embodiment, the fermentation vessel is provided with a valve at its outlet, the valve being used to control the opening and closing of the outlet.

[0017] The solid-liquid separation device in the aforementioned fermentation broth extraction equipment separates the fermentation broth from the fermentation mixture, removing solid waste such as culture medium residue. The separated fermentation broth enters the receiving chamber from the inlet of the fermentation vessel. An ultrasonic generator produces ultrasonic waves that directly act on the fermentation broth within the receiving chamber. Through cavitation, mechanical vibration, and thermal effects, the release of target components (such as metabolites and intracellular substances) from the cells into the solvent is accelerated, reducing component loss and shortening the extraction time. The ultrasonic generator ensures that all areas of the extract are subjected to ultrasonic action, improving the uniformity of component extraction. The outlet of the solid-liquid separation device is directly connected to the inlet of the fermentation vessel, forming an integrated continuous process of separation and extraction, reducing intermediate losses and improving production efficiency. Based on this, the fermentation broth extraction equipment of this application can reduce component loss in the fermentation broth, improve extraction efficiency, and achieve rapid and efficient extraction. Attached Figure Description

[0018] To more clearly illustrate the technical solutions in the embodiments of this application or the conventional technology, the drawings used in the description of the embodiments or the conventional technology will be briefly introduced below. Obviously, the drawings described below are only embodiments of this application. For those skilled in the art, other drawings can be obtained based on the disclosed drawings without creative effort.

[0019] Figure 1 is a schematic diagram of a fermentation broth extraction device provided in an embodiment of this application.

[0020] Explanation of reference numerals in the attached drawings: 100, Fermentation broth extraction equipment; 1, Solid-liquid separation device; 11, Discharge port; 2, Fermentation broth extraction device; 21, Fermentation container; 211, Receiving cavity; 212, Inlet; 213, Outlet; 214, Air inlet; 215, Valve; 22, Ultrasonic generator; 23, Stirrer; 231, Stirring motor; 232, Stirring paddle; 3, Gas conveying device; 31, Air outlet; 4, Temperature control device; 41, Liquid circulator; 411, First liquid inlet; 412, First liquid outlet; 42, Heat exchanger; 43, Temperature sensor. Detailed Implementation

[0021] To make the above-mentioned objectives, features, and advantages of this application more apparent and understandable, the specific embodiments of this application are described in detail below with reference to the accompanying drawings. Many specific details are set forth in the following description to provide a thorough understanding of this application. However, this application can be implemented in many other ways different from those described herein, and those skilled in the art can make similar modifications without departing from the spirit of this application. Therefore, this application is not limited to the specific embodiments disclosed below.

[0022] Current fermentation broth extraction devices suffer from low extraction efficiency and significant loss of fermentation broth components, making rapid and efficient extraction difficult. To address these issues, this application provides a fermentation broth extraction device. This device 100 includes a solid-liquid separation unit 1, a fermentation broth extraction unit 2, a gas conveying unit 3, and a temperature control unit 4.

[0023] Referring to Figure 1, in some embodiments, the solid-liquid separation device 1 is provided with a discharge port 11; the fermentation broth extraction device 2 includes a fermentation container 21 and an ultrasonic generator 22. The fermentation container 21 is provided with a receiving cavity 211 and an inlet 212 and an outlet 213 communicating with the receiving cavity 211. The inlet 212 is connected to the discharge port 11, and the ultrasonic generator 22 is mounted on the fermentation container 21. The solid-liquid separation device 1 separates the fermentation broth from the fermentation mixture, removing solid waste such as culture medium residue. The separated fermentation broth enters the receiving cavity 211 from the inlet 212 of the fermentation container 21. The ultrasonic generator 22 generates ultrasonic waves, which directly act on the fermentation broth in the receiving cavity 211. Through cavitation effect, mechanical vibration, and thermal effect, it accelerates the release of target components (such as metabolites and intracellular substances) from the cells to the solvent, reduces the loss of fermentation broth components, and shortens the extraction time. The ultrasonic generator 22 can ensure that all areas of the extract are subjected to ultrasonic action, improving the uniformity of component extraction. The discharge port 11 of the solid-liquid separation device 1 is directly connected to the inlet 212 of the fermentation vessel 21, forming an integrated continuous process of separation and extraction, reducing losses in intermediate steps and improving production efficiency. Based on this, the fermentation broth extraction equipment 100 of this application can reduce the loss of fermentation broth components, improve extraction efficiency, and achieve rapid and efficient extraction.

[0024] In an optional embodiment, the solid-liquid separation device 1 can be a filter press or a centrifuge, for example, a plate and frame filter press or a belt filter press.

[0025] Referring to Figure 1, in some embodiments, the solid-liquid separation device 1 includes a filter press, which has a discharge port 11. Filter presses are commercially available, and their specific structure will not be described in detail here. Taking a plate and frame filter press as an example, a plate and frame filter press consists of basic components such as filter plates, filter frames, and a frame. It has no complex transmission or sealing structures, making its manufacturing and assembly relatively simple. It can process fermentation broths with high solid content, improving filtration efficiency through pressurization, and is particularly suitable for systems with high viscosity. The filtration area can be adjusted by increasing or decreasing the number of filter plates to meet different processing capacity requirements.

[0026] Referring to Figure 1, in an optional embodiment, the ultrasonic generator 22 can be a focused ultrasonic generator 22 or a multi-probe ultrasonic generator 22. The ultrasonic generator 22 is commercially available, and its specific structure will not be described in detail here.

[0027] Referring to Figure 1, in some embodiments, the fermentation broth extraction device 2 further includes a stirrer 23, which includes a stirring motor 231 and a stirring paddle 232. The main body of the stirring motor 231 is located outside the receiving cavity 211, while the output end of the stirring motor 231 and the stirring paddle 232 are both located inside the receiving cavity 211. The output end of the stirring motor 231 is connected to the stirring paddle 232. The stirring motor 231 can drive the stirring paddle 232 to rotate. The mechanical movement of the stirring paddle 232 can promote the circulation of the fermentation broth within the receiving cavity 211, breaking down local concentration gradients and ensuring uniform mixing of substrates, microorganisms, enzymes, and other components. In aerobic fermentation, this ensures uniform distribution of dissolved oxygen, preventing abnormal microbial metabolism due to local hypoxia. In enzyme-catalyzed reactions, it accelerates the contact between the substrate and the enzyme, increasing the reaction rate. Stirring allows cavitation bubbles generated by ultrasound to be distributed more evenly in the fermentation broth, preventing cavitation from concentrating in localized areas due to fluid stasis, thereby improving overall extraction efficiency. When ultrasonic waves break down microbial cells, stirring can propel the cell suspension through the ultrasonic wave zone, ensuring that each cell can fully contact the cavitation energy and improving the cell disruption rate.

[0028] In an optional embodiment, the stirring motor 231 is a servo rotary motor or a stepper rotary motor.

[0029] Referring to Figure 1, in some embodiments, a valve 215 is provided at the outlet 213 of the fermentation container 21. The valve 215 is used to control the opening and closing of the outlet 213. When the valve 215 is open, the fermentation liquid extracted in the fermentation container 21 can be discharged from the outlet 213. When the valve 215 is closed, the extracted fermentation liquid is retained in the fermentation container 21.

[0030] In an optional embodiment, valve 215 may be a pneumatic solenoid valve or a pneumatic diaphragm valve, etc.

[0031] Referring to Figure 1, in some embodiments, the fermentation container 21 is further provided with an air inlet 214, which communicates with the containing cavity 211. The fermentation broth extraction device 100 also includes a gas conveying device 3, which is located outside the fermentation container 21, and its outlet 31 communicates with the air inlet 214. The gas conveying device 3 is used to deliver air into the fermentation container 21, as the microorganisms in the fermentation broth require air to survive during fermentation.

[0032] In an optional embodiment, the gas delivery device 3 may be an air pump, an air compressor, or a gas filtration system, etc.

[0033] Referring to Figure 1, in some embodiments, the gas delivery device 3 includes an air compressor, with the air outlet 31 connected to the air inlet 214. The air compressor draws in and pressurizes atmospheric air through mechanical compression, outputting a stable flow of compressed air to meet the ventilation requirements of different fermentation scales. The air compressor is commercially available, and its structure will not be described in detail here.

[0034] Referring to Figure 1, in some embodiments, the fermentation broth extraction device 100 further includes a temperature control device 4 located outside the fermentation vessel 21. The temperature control device 4 is used to control the temperature of the fermentation vessel 21. This can reduce product degradation or inactivation and maintain the activity of bacterial enzymes and the stability of the product.

[0035] Please refer to Figure 1. In optional embodiments, the temperature control device 4 can be a steam heating device, a circulating water insulation device, a heat transfer oil insulation device, or an electric heating insulation device, etc.

[0036] Referring to Figure 1, in some embodiments, the temperature control device 4 includes a liquid circulator 41 and a heat exchanger 42. The heat exchanger 42 is located outside the fermentation vessel 21. The liquid circulator 41 has a first inlet 411 and a first outlet 412. The heat exchanger 42 has a liquid storage chamber and a second inlet and a second outlet communicating with the liquid storage chamber. The second inlet is connected to the first outlet 412, and the second outlet is connected to the first inlet 411, forming a fluid circulation path between the liquid circulator 41 and the heat exchanger 42. The liquid circulator 41 supplies liquid at a certain temperature; the liquid can be oil or water. After the liquid enters the heat exchanger 42, the heat exchanger 42 transfers temperature to the fermentation vessel 21, achieving the function of heat preservation and temperature control for the fermentation vessel 21. Understandably, the liquid in the liquid circulation system exits through the first outlet 412, enters the storage chamber of the heat exchanger 42 through the second inlet, and the heat exchanger 42 keeps the fermentation vessel 21 warm. The liquid flows out from the second outlet, passes through the first inlet 411, and enters the liquid circulator 41. Temperature control and insulation of the fermentation vessel 21 are achieved through the circulation of the liquid between the heat exchanger 42 and the liquid circulator 41.

[0037] Referring to Figure 1, in some embodiments, the liquid circulator 41 includes a water bath and a pump body. The water bath has a first inlet 411 and a first outlet 412, and the pump body has a third inlet and a third outlet. The third inlet is connected to the first outlet 412, and the third outlet is connected to the second inlet. The water bath is used to store water, and the pump body is used to pump water, causing the water to circulate between the water bath and the heat exchanger 42, providing power for the water flow. It is understood that the water in the water bath flows out from the first outlet 412, enters the third inlet of the pump body, is pumped by the pump body, exits from the third outlet, enters the second inlet of the heat exchanger 42, then flows through the storage chamber of the heat exchanger 42 to exchange heat with the fermentation container 21, and finally flows out from the second outlet of the heat exchanger 42 and back into the first inlet 411 of the water bath.

[0038] Please refer to Figure 1. In an optional embodiment, the pump body can be a centrifugal pump or a circulating pump. The water bath is commercially available, and its specific structure will not be described in detail here.

[0039] Referring to Figure 1, in some embodiments, the temperature control device 4 further includes a temperature sensor 43, which is disposed inside the receiving cavity 211 of the fermentation container 21. By providing the temperature sensor 43, the temperature inside the fermentation container 21 can be detected, facilitating temperature control.

[0040] Please refer to Figure 1. In an optional embodiment, the temperature sensor 43 may be a resistance temperature sensor 43, a semiconductor temperature sensor 43, etc.

[0041] Please refer to Figure 1. The working principle of the fermentation broth extraction device 100 of this application will be specifically described below with reference to a specific embodiment: After the solid waste of the fermentation mixture is separated by the solid-liquid separation device 1, the fermentation broth is left. The fermentation broth is discharged from the outlet 11 of the solid-liquid separation device 1 and enters the fermentation container 21. The ultrasonic generator 22 is activated to extract the fermentation broth, the stirrer 23 is activated to stir the fermentation broth, the gas conveying device 3 is activated to introduce air into the fermentation container 21, and the liquid circulator 41 of the temperature control device 4 is activated to keep the fermentation container 21 warm by the heat exchanger 42. After the fermentation container 21 has completed the extraction, the valve 215 is activated to allow the extracted fermentation broth to be discharged from the outlet 213 of the fermentation container 21.

[0042] In the description of this application, it should be understood that if terms such as "center", "longitudinal", "lateral", "length", "width", "thickness", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise", "axial", "radial", "circumferential" appear, these terms indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings, and are only for the convenience of describing this application and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of this application.

[0043] Furthermore, where the terms "first" and "second" appear, these terms are for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of technical features indicated. Thus, a feature defined with "first" or "second" may explicitly or implicitly include at least one of that feature. In the description of this application, where the term "multiple" appears, "multiple" means at least two, such as two, three, etc., unless otherwise explicitly specified.

[0044] In this application, unless otherwise expressly specified and limited, the terms "installation," "connection," "joining," and "fixing," etc., should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral part; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; they can refer to the internal communication of two components or the interaction between two components, unless otherwise expressly limited. Those skilled in the art can understand the specific meaning of the above terms in this application based on the specific circumstances.

[0045] In this application, unless otherwise expressly specified and limited, the use of descriptions such as "above" or "below" the second feature indicates that the first and second features are in direct contact or indirect contact via an intermediate medium. Furthermore, "above," "on top of," and "over" the second feature can mean that the first feature is directly above or diagonally above the second feature, or simply that the first feature is at a higher horizontal level than the second feature. Similarly, "below," "below," and "under" the second feature can mean that the first feature is directly below or diagonally below the second feature, or simply that the first feature is at a lower horizontal level than the second feature.

[0046] It should be noted that if an element is referred to as being "fixed to" or "set on" another element, it can be directly on the other element or there may be an intervening element. If an element is considered to be "connected to" another element, it can be directly connected to the other element or there may be an intervening element. If so, the terms "vertical," "horizontal," "upper," "lower," "left," "right," and similar expressions used in this application are for illustrative purposes only and do not represent the only possible implementation.

[0047] The technical features of the above embodiments can be combined in any way. For the sake of brevity, not all possible combinations of the technical features in the above embodiments are described. However, as long as there is no contradiction in the combination of these technical features, they should be considered to be within the scope of this specification.

[0048] The embodiments described above are merely illustrative of several implementation methods of this application, and while the descriptions are relatively specific and detailed, they should not be construed as limiting the scope of the patent application. It should be noted that those skilled in the art can make various modifications and improvements without departing from the concept of this application, and these all fall within the protection scope of this application. Therefore, the protection scope of this patent application should be determined by the appended claims.

Claims

1. A fermentation broth extraction device, characterized in that, include: A solid-liquid separation device, wherein the solid-liquid separation device is provided with a discharge port; a fermentation broth extraction device, wherein the fermentation broth extraction device includes a fermentation container and an ultrasonic generator, the fermentation container is provided with a receiving cavity and an inlet and an outlet communicating with the receiving cavity, the inlet being connected to the discharge port, and the ultrasonic generator being disposed on the fermentation container.

2. The fermentation broth extraction equipment according to claim 1, characterized in that, The fermentation container is also provided with an air inlet, which is connected to the containment cavity. The fermentation liquid extraction equipment also includes a gas conveying device, which is located outside the fermentation container and whose outlet is connected to the air inlet.

3. The fermentation broth extraction equipment according to claim 2, characterized in that, The gas delivery device includes an air compressor, and the air outlet of the air compressor is connected to the air inlet.

4. The fermentation broth extraction equipment according to claim 1, characterized in that, The fermentation broth extraction equipment also includes a temperature control device located outside the fermentation container, which is used to control the temperature of the fermentation container.

5. The fermentation broth extraction device according to claim 4, characterized in that, The temperature control device includes a liquid circulator and a heat exchanger. The heat exchanger is located outside the fermentation vessel. The liquid circulator has a first inlet and a first outlet. The heat exchanger has a liquid storage chamber and a second inlet and a second outlet connected to the liquid storage chamber. The second inlet is connected to the first outlet, and the second outlet is connected to the first inlet, so as to form a fluid circulation path between the liquid circulator and the heat exchanger.

6. The fermentation broth extraction device according to claim 5, characterized in that, The liquid circulator includes a water bath and a pump body. The water bath is provided with a first liquid inlet and a first liquid outlet. The pump body is provided with a third liquid inlet and a third liquid outlet. The third liquid inlet is connected to the first liquid outlet, and the third liquid outlet is connected to the second liquid inlet.

7. The fermentation broth extraction equipment according to claim 4, characterized in that, The temperature control device also includes a temperature sensor, which is located inside the containment cavity of the fermentation vessel.

8. The fermentation broth extraction apparatus according to any one of claims 1 to 7, characterized in that, The fermentation broth extraction device also includes a stirrer, which includes a stirring motor and a stirring paddle. The main body of the stirring motor is located outside the receiving cavity, while the output end of the stirring motor and the stirring paddle are both located inside the receiving cavity. The output end of the stirring motor is driven and connected to the stirring paddle.

9. The fermentation broth extraction apparatus according to any one of claims 1 to 7, characterized in that, The solid-liquid separation device includes a filter press, and the filter press is provided with the discharge port.

10. The fermentation broth extraction apparatus according to any one of claims 1 to 7, characterized in that, The fermentation vessel is equipped with a valve at its outlet, which is used to control the opening and closing of the outlet.

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