Focus-adjustable optical detection device for analytical ultra-speed centrifuge

Abstract

The utility model provides the focusable optical detection device for the analytical ultra-speed centrifuge, the device adopts a split structure of the connecting rod group and the light beam focuser, so that the light beam focuser can move along the axial direction of the connecting rod, and when different heights of the same sample pool are detected, the focusable optical detection device can be used for detecting different heights of the sample pool. The height of a light beam focusing position can be adjusted by adjusting the position of the light beam focuser on the connecting rod, so that each height in the sample cell can be accurately measured; when sample cells with different thicknesses are detected, the height of the light beam focusing position can be adjusted by adjusting the position of the light beam focuser on the connecting rod, so that the light beam focus is always in the central position of the sample cell. In the process, new parts do not need to be customized and replaced again, and the detection device does not need to be checked again, so that the detection cost is reduced, and the detection flexibility and the detection efficiency are both improved.

Description

Adjustable-focus optical detection device for analytical ultracentrifuges Technical Field

[0001] This utility model relates to the field of analytical ultracentrifuge technology, and in particular to an adjustable-focus optical detection device for analytical ultracentrifuges. Background Technology

[0002] Analytical ultracentrifuges (AUCs) are important separation and characterization devices in biochemistry and materials science. They use high centrifugal acceleration to drive molecules or particles to settle in solution, thereby allowing the study of their physicochemical properties (such as molecular weight, shape, and aggregation state). This technology is widely used in the analysis of samples such as proteins, nucleic acids, viruses, and nanoparticles.

[0003] Various analytical ultracentrifuges exist in the prior art. For example, patent US7294513B2 discloses a method and apparatus for characterizing small particle solutions. While this apparatus can achieve sample separation and detection, it has certain shortcomings in practical use. Specifically, this apparatus can only detect a sample cell at a fixed height in the rotor and an optical signal at a fixed height within the same sample cell. However, with the development of detection technology, the overall thickness of the sample cell is becoming more diverse. Compared to conventional analytical ultracentrifugation, the overall thickness of the sample cell is reduced in the detection of micro-samples to improve detection sensitivity. For high solution densities or some special optical detection requirements, the thickness of the sample cell is further increased compared to conventional detection. Furthermore, there is also a need to detect optical signals at different heights within the same sample cell. Changes in sample cell thickness and detection height require changes in the focusing position of the light beam within the sample cell. In such cases, the optical detection device described above, which can only measure sample cells of fixed height and the same sample cell at a fixed height, is no longer applicable. New components often need to be custom-made to meet the detection requirements, which increases design and production costs. Furthermore, replacing components requires recalibrating the detection device, which significantly increases detection time and reduces detection efficiency.

[0004] Therefore, existing optical detection devices for analytical ultracentrifuges suffer from technical problems such as high detection costs, poor flexibility, and low efficiency, and need to be improved. Summary of the Invention

[0005] This embodiment provides an adjustable-focus optical inspection device for analytical ultracentrifuges, which solves the technical problems of high inspection cost, poor flexibility, and low efficiency of current optical inspection devices for analytical ultracentrifuges.

[0006] To address the aforementioned technical problems, this embodiment provides the following technical solution:

[0007] This embodiment provides an adjustable-focus optical detection device for an analytical ultracentrifuge, comprising:

[0008] Base;

[0009] A translation adjustment platform is disposed at the top of the base, with a first end of the translation adjustment platform fixedly connected to the base and a second end of the translation adjustment platform suspended in the air;

[0010] A light emitting component is disposed at the top of the translation adjustment stage, and the light emitting component is used to emit a light beam along a first direction;

[0011] A connecting rod assembly is disposed at the bottom end of the translation adjustment platform. The connecting rod assembly includes N connecting rods. The first end of the connecting rod assembly is connected to the second end of the translation adjustment platform. The axial direction of each connecting rod is parallel to the first direction. N is a positive integer.

[0012] A beam focuser is slidably connected to the second end of the connecting rod assembly along the axial direction, and the beam focuser is used to focus the beam.

[0013] A light receiving component is fixedly connected to the translation adjustment stage and is disposed on the light output path of the light beam. The light receiving component is used to receive the light beam after it has been focused and emitted.

[0014] In one embodiment, the beam focuser includes a focusing lens, a mounting hole extending along the axial direction, and N connecting holes extending along the axial direction. The focusing lens is mounted in the mounting hole, and the N connecting rods are respectively sleeved in the N connecting holes.

[0015] In one embodiment, each of the connection holes is arranged around the mounting hole.

[0016] In one embodiment, the distance between each of the connecting holes and the mounting holes is equal, and the connecting holes are evenly spaced.

[0017] In one embodiment, the beam focuser includes N fixing members and N fixing holes, the N fixing holes being perpendicularly connected to the N connecting holes, and the N fixing members being installed in the N fixing holes to fix the beam focuser at the current position of the connecting rod assembly.

[0018] In one embodiment, the fixing member is a screw with a nylon head. When the screw is tightened, the beam focuser is fixedly connected to the connecting rod. When the screw is not tightened, the beam focuser can slide along the axial direction of the connecting rod.

[0019] In one embodiment, the beam focuser includes a focusing lens adjustment knob. When the focusing lens adjustment knob is rotated, the focusing lens moves along the focusing plane of the beam focuser, and the focusing plane is perpendicular to the first direction.

[0020] In one embodiment, the connecting rod includes a plurality of reference scale lines, which are arranged at equal intervals along the axial direction.

[0021] In one embodiment, the translation adjustment platform includes a translation platform base and a translation platform. The bottom end of the translation platform base is fixedly connected to the top end of the base. The top end of the translation platform base and the bottom end of the translation platform are slidably connected along a second direction and a third direction via cross roller guides. The second direction and the third direction are both perpendicular to the first direction, and the second direction is opposite to the third direction.

[0022] In one embodiment, the light emitting assembly includes a light emitting unit and a first light deflector, the light emitting unit being used to emit a light beam along a second direction, and the first light deflector being used to deflect the light beam along the first direction, the second direction being perpendicular to the first direction.

[0023] In one embodiment, the light receiving component includes a light receiving unit and a second light deflector, the second light deflector being used to deflect the light beam emitted along the first direction to a third direction, and the light receiving unit being used to receive the converted light beam, the third direction being perpendicular to the first direction.

[0024] The beneficial effects of this embodiment are as follows: This embodiment provides an adjustable-focus optical detection device for analytical ultracentrifuges. The device adopts a separate structure for the connecting rod assembly and the beam focuser, allowing the beam focuser to move axially along the connecting rod. When detecting different heights of the same sample cell, the height of the beam focus position can be adjusted by adjusting the position of the beam focuser on the connecting rod, enabling accurate measurement of all heights within the sample cell. Similarly, when detecting sample cells of varying thicknesses, the height of the beam focus position can be adjusted by adjusting the position of the beam focuser on the connecting rod, ensuring the beam focal point remains at the center of the sample cell. All of the above processes do not require the customization or replacement of new components, nor do they require recalibration of the detection device, thereby reducing detection costs and improving detection flexibility and efficiency. Attached Figure Description

[0025] To more clearly illustrate the technical solutions in this embodiment, the accompanying drawings used in the description of the embodiment will be briefly introduced below. Obviously, the drawings described below are only some embodiments of this utility model. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0026] Figure 1 is a schematic diagram of the first structure of the adjustable-focus optical detection device for an analytical ultracentrifuge provided in an embodiment of the present invention.

[0027] Figure 2 is a schematic diagram of the second structure of the adjustable-focus optical detection device for an analytical ultracentrifuge provided in an embodiment of the present invention.

[0028] Figure 3 is a schematic diagram of the third structure of the adjustable-focus optical detection device for an analytical ultracentrifuge provided in an embodiment of the present invention.

[0029] Figure 4 is a schematic diagram of the fourth structure of the adjustable-focus optical detection device for an analytical ultracentrifuge provided in the embodiment of this utility model.

[0030] Figure 5 is a schematic diagram of the fifth structure of the adjustable-focus optical detection device for an analytical ultracentrifuge provided in the embodiment of this utility model.

[0031] Explanation of reference numerals in the attached figures:

[0032] Base 10; Translation adjustment stage 20; Light emitting assembly 30; Connecting rod assembly 40; Beam focuser 50; Light receiving assembly 60; Translation stage base 21; Translation stage 22; Cross roller guide 200; Light transmission hole 201; Light emitting unit 31; First light diverter 32; First fixed bracket 311; Light signal transmitter 312; First light signal transmitter fixing hole 301; Second light signal transmitter fixing hole 302; Light signal transmitter mounting hole 303; Second fixed bracket 321; Incident light adjustment mirror 322; Incident light adjustment mirror fixing hole 304; Incident light adjustment mirror mounting hole 305; First connecting rod 41; Second connecting rod 42; Third Connecting rod 43; fourth connecting rod 44; mounting hole 51; first connecting hole 521; second connecting hole 522; third connecting hole 523; fourth connecting hole 524; first fixing hole 531; second fixing hole 532; third fixing hole 533; fourth fixing hole 534; front and rear adjustment knob 54; left and right adjustment knob 55; light receiving unit 61; second light diverter 62; third fixing bracket 611; light signal receiver 612; light signal receiver fixing hole 601; light signal receiver mounting hole 602; fourth fixing bracket 621; emitted light adjustment mirror 622; adapter frame 600; first direction Y; second direction X1; third direction X2. Detailed Implementation

[0033] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present utility model. In addition, it should be understood that the specific embodiments described herein are only for illustration and explanation of the present utility model and are not intended to limit the present utility model. In the present utility model, unless otherwise stated, directional terms such as "upper" and "lower" generally refer to the upper and lower positions of the device in actual use or operation, specifically the drawing directions in the accompanying drawings; while "inner" and "outer" refer to the outline of the device.

[0034] As shown in Figures 1 to 5, the device includes a base 10, a translation adjustment platform 20, a light emitting component 30, a connecting rod group 40, a beam focuser 50, and a light receiving component 60. The translation adjustment platform 20 is located at the top of the base 10, with its first end fixedly connected to the base 10 and its second end suspended. The light emitting component 30 is located at the top of the translation adjustment platform 20 and is used to emit a light beam along a first direction Y. The connecting rod group 40 is located at the bottom of the translation adjustment platform 20 and includes N connecting rods. The first end of the connecting rod group 40 is connected to the second end of the translation adjustment platform 20, and the axial direction of each connecting rod is parallel to the first direction, where N is a positive integer. The beam focuser 50 is slidably connected to the second end of the connecting rod group 40 along the axial direction and is used to focus the light beam. The light receiving component 60 is fixedly connected to the translation adjustment platform 20 and is located on the light beam's exit path, used to receive the focused light beam.

[0035] The base 10 provides support for other structures. During use, the bottom of the base 10 contacts other components, and it remains fixed while adjusting the positions of other structures within the device. The first end of the translation adjustment platform 20 is fixed to the top of the base 10, while the second end is suspended; this suspended portion can be used to fix other structures. The light emitting component 30 is located at the top of the translation adjustment platform 20 and is used to emit a light beam. The light beam ultimately exits along a first direction Y, which can specifically be a vertically downward direction.

[0036] A connecting rod assembly 40 is disposed at the bottom end of the translation adjustment platform 20, and includes at least one connecting rod. The number of connecting rods is not limited and can be set as needed. This embodiment uses four connecting rods for illustration, so the connecting rod assembly 40 may include a first connecting rod 41, a second connecting rod 42, a third connecting rod 43, and a fourth connecting rod 44. The first end of the connecting rod assembly 40 is connected to the second end of the translation adjustment platform 20, meaning the first end of each connecting rod is fixed to the second end of the translation adjustment platform 20. The fixing method can be threaded fixing, adhesive fixing, etc., and this embodiment does not limit the fixing method. The axial direction of each connecting rod is parallel to the first direction Y, that is, the axial direction is vertical, including vertically upward and vertically downward.

[0037] The beam focuser 50 is used to receive and focus the beam along the first direction Y. The beam focuser 50 is slidably connected to the second end of the connecting rod assembly 40 and can move along the axial direction of each connecting rod, including vertically upward and vertically downward. When the beam focuser 50 moves to different heights, the position of the focused beam focal point also changes. When the device needs to perform optical detection, the sample cell of the analytical ultracentrifuge is placed directly below the beam focuser 50. By moving the beam focuser 50 vertically, the beam focal point can be positioned precisely at the optimal detection position in the sample cell, achieving the best detection effect.

[0038] After the light beam is focused and detected at the center of the sample cell, it continues to be emitted along the first direction Y. The light receiving component 60 is set on the light emission path of the light beam and is fixedly connected to the translation adjustment stage 20. The light receiving component 60 receives the emitted light beam and obtains the optical detection result after subsequent processing.

[0039] In existing technologies, the position of the beam focuser inside the optical detection device is fixed, which also makes the position of the beam focal point fixed. Therefore, it can only detect sample cells of fixed thickness and fixed height of the same sample cell. It is no longer suitable for scenarios that require detection of sample cells of different heights or different thicknesses. New components are often required to meet the detection requirements, resulting in low detection efficiency.

[0040] In this embodiment, the device employs a separate structure for the connecting rod assembly and the beam focuser. This allows the beam focuser to move axially along the connecting rod. When detecting different heights of the same sample cell, the beam focus position can be adjusted by changing the position of the beam focuser on the connecting rod, enabling precise measurement of all heights within the sample cell. Similarly, when detecting sample cells of varying thicknesses, the beam focus position can be adjusted by changing the position of the beam focuser on the connecting rod, ensuring the beam focal point remains centered within the sample cell. All of these processes eliminate the need for custom-made or replaced components, as well as recalibration of the detection device, thereby reducing detection costs and improving both detection flexibility and efficiency.

[0041] In one embodiment, the beam focuser includes a focusing lens, an axially extending mounting hole, and N axially extending connecting holes. The focusing lens is mounted in the mounting hole, and the N connecting rods are respectively sleeved in the N connecting holes.

[0042] The beam focuser 50 includes a focusing lens (not shown), a mounting hole 51, and a connecting hole, both of which extend along the axial direction of the connecting rod. The focusing lens is disposed within the mounting hole 51, and can be fixed by means of a threaded snap ring or by adhesive, etc. This embodiment does not limit the mounting method of the focusing lens. The focusing lens is used to focus the beam, and the focusing lens can be selected according to the detection requirements. The number of connecting holes is equal to the number of connecting rods. Taking a total of four connecting rods as an example, the connecting holes may specifically include a first connecting hole 521, a second connecting hole 522, a third connecting hole 523, and a fourth connecting hole 524. Each connecting hole corresponds one-to-one with each connecting rod; that is, the first connecting rod 41 is fitted into the first connecting hole 521, the second connecting rod 42 is fitted into the second connecting hole 522, the second connecting rod 43 is fitted into the second connecting hole 523, and the second connecting rod 44 is fitted into the second connecting hole 524. By setting a focusing lens, the beam can be focused. By setting connecting holes and fitting them together, a sliding connection can be achieved between the beam focusr 50 and the connecting rod assembly 40. The two work together to provide flexible detection. Furthermore, since the beam focusr 50 and the connecting rod assembly 40 adopt a split structure, the beam focusr 50 can be easily detached from the connecting rod assembly 40. When the length of the connecting rod assembly 40 is insufficient to meet the movement range of the beam focusr 50, different focusing lenses can be easily replaced to meet the detection requirements.

[0043] In one embodiment, the connecting holes are arranged around the mounting hole. The first connecting hole 521, the second connecting hole 522, the third connecting hole 523 and the fourth connecting hole 524 are arranged around the mounting hole 51. Since the connecting holes are distributed around the focusing lens, the connecting rods that cooperate with them will not be located on the focusing path of the focusing lens, so they will not cause unnecessary obstruction to the beam. This ensures both the sliding connection effect and the optical detection effect.

[0044] In one embodiment, the distances between each connecting hole and the mounting hole are equal, and the connecting holes are spaced evenly. This equal distance and even spacing ensures that the beam focuser 50 experiences uniform force at each connecting hole, which helps maintain the beam focuser 50 at a horizontal position and thus guarantees detection accuracy.

[0045] In one embodiment, the beam focuser includes N fixing members and N fixing holes. The N fixing holes are perpendicularly connected to the N connecting holes, and the N fixing members are installed in the N fixing holes to fix the beam focuser at the current position of the connecting rod assembly.

[0046] The beam focuser 50 includes fixing components (not shown) and fixing holes. The number of fixing components and fixing holes is equal to the number of connecting rods. When the number of connecting rods is 4, the fixing components include a first fixing component, a second fixing component, a third fixing component, and a fourth fixing component. The fixing holes include a first fixing hole 531, a second fixing hole 532, a third fixing hole 533, and a fourth fixing hole 534. Each fixing hole is perpendicular to each connecting hole. Since each connecting hole is axially connected to the connecting rod, that is, vertically connected, each fixing hole is horizontally connected to each connecting hole. Specifically, the first fixing hole 531 is perpendicular to the first connecting hole 521, the second fixing hole 532 is perpendicular to the second connecting hole 522, the third fixing hole 533 is perpendicular to the third connecting hole 523, and the fourth fixing hole 534 is perpendicular to the fourth connecting hole 524. Each fixing component is installed in a fixing hole to fix the beam focuser in the current position of the connecting rod assembly. Specifically, the first fixing component is installed in the first fixing hole 531 to fix the beam focuser 50 to the first connecting rod 41; the second fixing component is installed in the second fixing hole 532 to fix the beam focuser 50 to the second connecting rod 42; the third fixing component is installed in the third fixing hole 533 to fix the beam focuser 50 to the third connecting rod 43; and the fourth fixing component is installed in the fourth fixing hole 534 to fix the beam focuser 50 to the fourth connecting rod 44.

[0047] The beam focuser 50 can move along the axial direction of each connecting rod, but it tends to fall vertically downwards under the influence of gravity. When it moves to a suitable position, it needs to be fixed to maintain that position. This embodiment achieves good fixation by providing fixing holes and fixing components, ensuring that the beam focus remains in the optimal position during optical inspection.

[0048] In one embodiment, the fixing member is a screw with a nylon head. When the screw is tightened, the beam focuser is fixedly connected to the connecting rod. When the screw is not tightened, the beam focuser can slide along the axial direction of the connecting rod.

[0049] The fixing component can be a screw with a nylon tip. The nylon tip enhances friction, preventing the connecting rod from loosening or slipping, thus providing better fixation. When the screw is tightened, the screw tip contacts the connecting rod at the junction of the connecting hole and the fixing hole, providing good fixation. When not tightened, the screw tip separates from the connecting rod at the junction of the connecting hole and the fixing hole, allowing the beam focuser 50 to move flexibly up and down, and also allowing the beam focuser 50 to be easily detached from the connecting rod assembly 40.

[0050] In one embodiment, the beam focuser includes a focusing lens adjustment knob, which, when rotated, moves the focusing lens along the focusing plane of the beam focuser, the focusing plane being perpendicular to a first direction.

[0051] The beam focuser 50 also includes focusing lens adjustment knobs, specifically a front-to-back adjustment knob 54 and a left-to-right adjustment knob 55. Rotating the front-to-back adjustment knob 54 allows the focusing lens to move back and forth along the focusing plane of the beam focuser 50. Rotating the left-to-right adjustment knob 55 allows the focusing lens to move left and right along the focusing plane of the beam focuser 50. The focusing plane is perpendicular to the first direction Y, i.e., the focusing plane is horizontal. By rotating these two knobs, the horizontal position of the focusing lens in the beam focuser can be conveniently and precisely adjusted, improving the detection accuracy.

[0052] In one embodiment, the connecting rod includes multiple reference scale lines arranged at equal intervals along the axial direction.

[0053] The connecting rod is equipped with multiple reference scale lines, which are evenly spaced along the axial direction of the connecting rod, and the extension direction of each reference scale line is perpendicular to the arrangement direction. The spacing between adjacent reference scale lines can be set according to the detection requirements; the smaller the spacing, the higher the measurement accuracy. A fixed number of reference scale lines at intervals can simultaneously display the corresponding reference scale values. Because of the reference scale lines, when measuring different heights of the same sample cell, the position of the beam focuser 50 can be moved based on these scale lines to achieve accurate measurement.

[0054] In one embodiment, the translation adjustment table includes a translation table base and a translation table. The bottom end of the translation table base is fixedly connected to the top end of the base. The top end of the translation table base and the bottom end of the translation table are slidably connected by cross roller guides along a second direction and a third direction. The second direction and the third direction are both perpendicular to the first direction, and the second direction is opposite to the third direction.

[0055] The translation adjustment table 20 includes a translation table base 21 and a translation table 22. The bottom end of the translation table base 21 is fixedly connected to the top end of the base 10. At least one set of crossed roller guide rails 200 is provided between the top end of the translation table base 21 and the bottom end of the translation table 22. Each set of crossed roller guide rails 200 includes two guide rails with raceways, a roller retainer, and rollers. The two guide rails are fixed to the top end of the translation table base 21 and the bottom end of the translation table 22, respectively. The fixing can be vertical or horizontal. Under the action of external force, the rollers arranged in a cross pattern reciprocate on the raceways, realizing the sliding connection between the translation table base 21 and the translation table 22. The guide rails extend along the second direction X1 and the third direction X2, so the translation table base 21 and the translation table 22 are slidably connected along the second direction X1 and the third direction X2. The second direction X1 and the third direction X2 are both perpendicular to the first direction Y, that is, both are horizontal directions. By sliding the translation stage 22, the horizontal distance between the beam focuser 50 and the base 10 can be flexibly adjusted, thereby meeting the requirements for horizontal placement and detection of the sample cell.

[0056] In one embodiment, the light emitting assembly includes a light emitting unit and a first light deflector, the light emitting unit being used to emit a light beam along a second direction, and the first light deflector being used to deflect the light beam along a first direction, the second direction being perpendicular to the first direction.

[0057] The light emitting assembly 30 specifically includes a light emitting unit 31 and a first light diverter 32. The light emitting unit 31 includes a first fixing bracket 311 and a light signal transmitter 312. The bottom end of the first fixing bracket 311 is fixed to the top end of the platform 22. The first fixing bracket 311 includes a first light signal transmitter fixing hole 301, a second light signal transmitter fixing hole 302, and a light signal transmitter mounting hole 303. The first light signal transmitter fixing hole 301 and the second light signal transmitter fixing hole 302 are used to fix the light signal transmitter 312, and the light signal transmitter mounting hole 303 is used to install the light signal transmitter 312. After installation, the light signal transmitter 312 emits a light beam along the second direction X1. The first beam diverter 32 includes a second fixed bracket 321 and an incident beam adjusting mirror 322. The bottom end of the second fixed bracket 321 is fixed to the top end of the platform 22. The second fixed bracket 321 includes an incident beam adjusting mirror fixing hole 304 and an incident beam adjusting mirror mounting hole 305. The incident beam adjusting mirror fixing hole 304 is used to fix the incident beam adjusting mirror 322, and the incident beam adjusting mirror mounting hole 305 is used to mount the incident beam adjusting mirror 322. The incident beam adjusting mirror 322 is placed at an angle to reflect the beam emitted along the second direction X1, causing it to continue to propagate vertically downward along the first direction Y. At the same time, a light-transmitting hole 201 is provided at a corresponding position on the translation stage 22, through which the diverted beam reaches the beam focuser 50.

[0058] Through the cooperation of the light emitting unit 31 and the first light deflector 32, a light beam incident along the first direction Y is finally obtained.

[0059] In one embodiment, the light receiving component includes a light receiving unit and a second light deflector. The second light deflector is used to deflect a light beam emitted along a first direction to a third direction. The light receiving unit is used to receive the converted light beam. The third direction is perpendicular to the first direction.

[0060] The optical receiving assembly 60 includes an optical receiving unit 61 and a second optical diverter 62. The optical receiving unit 61 includes a third mounting bracket 611 and an optical signal receiver 612. The third mounting bracket 611 includes an optical signal receiver mounting hole 601 and an optical signal receiver mounting hole 602. The optical signal receiver mounting hole 601 is used to fix the optical signal receiver 612; during installation, a screw with a nylon thread is passed through the optical signal receiver mounting hole 601 and tightened. The optical signal receiver mounting hole 602 is used to install the optical signal receiver 612. The second optical diverter 62 includes a fourth mounting bracket 621 and an outgoing light adjustment mirror 622. The outgoing light adjustment mirror 622 is tilted and fixed on the fourth mounting bracket 621. The focused beam of light first illuminates the outgoing light adjustment mirror 622, and after reflection, continues to propagate along a third direction X2. The continuing propagating beam of light is finally received by the optical signal receiver 612. The third fixed bracket 611 and the fourth fixed bracket 621 are fixedly connected or integrally formed, and together they form the adapter 600. The top of the adapter 600 is fixedly connected to the bottom of the translation stage 22. When the translation stage 22 moves along the second direction X1 and the third direction X2, the light emitting component 30 and the light receiving component 60 will move synchronously, so that the emission and reception of the light beam can be carried out normally.

[0061] Through the cooperation of the light receiving unit 61 and the second light diverter 62, the light beam emitted along the first direction Y is finally received.

[0062] The embodiments of this utility model have been described in detail above. Specific examples have been used to illustrate the principles and implementation methods of this utility model. The description of the above embodiments is only for the purpose of helping to understand the method and core ideas of this utility model. At the same time, for those skilled in the art, there will be changes in the specific implementation methods and application scope based on the ideas of this utility model. Therefore, the content of this specification should not be construed as a limitation of this utility model.

Claims

1. An adjustable-focus optical detection device for an analytical ultracentrifuge, characterized in that, include: Base; A translation adjustment platform is disposed at the top of the base, with a first end of the translation adjustment platform fixedly connected to the base and a second end of the translation adjustment platform suspended in the air; A light emitting component is disposed at the top of the translation adjustment platform, and the light emitting component is used to emit a light beam along a first direction; a connecting rod group is disposed at the bottom of the translation adjustment platform, the connecting rod group includes N connecting rods, the first end of the connecting rod group is connected to the second end of the translation adjustment platform, the axial direction of each connecting rod is parallel to the first direction, and N is a positive integer; A beam focuser is slidably connected to the second end of the connecting rod assembly along the axial direction, and the beam focuser is used to focus the beam. A light receiving component is fixedly connected to the translation adjustment stage and is disposed on the light output path of the light beam. The light receiving component is used to receive the light beam emitted after focusing.

2. The adjustable-focus optical detection device as described in claim 1, characterized in that, The beam focuser includes a focusing lens, a mounting hole extending along the axial direction, and N connecting holes extending along the axial direction. The focusing lens is installed in the mounting hole, and the N connecting rods are respectively sleeved in the N connecting holes.

3. The adjustable-focus optical detection device as described in claim 2, characterized in that, Each of the aforementioned connection holes is arranged around the mounting hole.

4. The adjustable-focus optical detection device as described in claim 3, characterized in that, The distance between each of the connecting holes and the mounting holes is equal, and the connecting holes are set at equal intervals.

5. The adjustable-focus optical detection device as described in claim 2, characterized in that, The beam focuser includes N fixing components and N fixing holes. The N fixing holes are perpendicular to the N connecting holes. The N fixing components are installed in the N fixing holes to fix the beam focuser at the current position of the connecting rod assembly.

6. The adjustable-focus optical detection device as described in claim 5, characterized in that, The fixing component is a screw with a nylon head. When the screw is tightened, the beam focuser is fixedly connected to the connecting rod. When the screw is not tightened, the beam focuser can slide along the axial direction of the connecting rod.

7. The adjustable-focus optical detection device as described in claim 2, characterized in that, The beam focuser includes a focusing lens adjustment knob. When the focusing lens adjustment knob is rotated, the focusing lens moves along the focusing plane of the beam focuser, and the focusing plane is perpendicular to the first direction.

8. The adjustable-focus optical detection device as described in claim 1, characterized in that, The connecting rod includes multiple reference scale lines, which are arranged at equal intervals along the axial direction.

9. The adjustable-focus optical detection device as described in claim 1, characterized in that, The translation adjustment platform includes a translation platform base and a translation platform. The bottom end of the translation platform base is fixedly connected to the top end of the base. The top end of the translation platform base and the bottom end of the translation platform are slidably connected along a second direction and a third direction by cross roller guides. The second direction and the third direction are both perpendicular to the first direction, and the second direction is opposite to the third direction.

10. The adjustable-focus optical detection device as described in claim 1, characterized in that, The light emitting assembly includes a light emitting unit and a first light deflector. The light emitting unit is used to emit a light beam along a second direction, and the first light deflector is used to deflect the light beam along the first direction. The second direction is perpendicular to the first direction.

11. The adjustable-focus optical detection device as described in claim 1, characterized in that, The optical receiving component includes an optical receiving unit and a second optical deflector. The second optical deflector is used to deflect the light beam emitted along the first direction to a third direction. The optical receiving unit is used to receive the converted light beam. The third direction is perpendicular to the first direction.

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