Multi-channel array sample application device for medicine detection

Abstract

The utility model discloses a multi-channel array sample application device for medicine detection, relates to the technical field of sample application devices, and aims to solve the technical problems that the distance between point positions of current multi-channel sample application is inconvenient to adjust, and the operability is poor, the multi-channel array sample application device comprises a bottom plate, a frame body, a shunt pipe, a sliding frame and a positioning cylinder, and a placing table is arranged in the middle of the upper end face of the bottom plate; supports are fixed to the two ends of the upper end face of the bottom plate, connecting frames are installed at the upper ends of the supports, the two connecting frames are connected through a top plate, the frame body is located on the lower sides of the connecting frames, sliding grooves are formed in the two sides of the two ends of the frame body, and the sliding frames are installed in the sliding grooves in the corresponding ends of the frame body in a sliding mode. Sample application heads are fixedly mounted at the two lower ends of the flow dividing pipe and are inserted into the corresponding positioning cylinders. The double-channel sample application device has the advantages of double-channel sample application design capable of adjusting the sample application distance and high operability.

Description

Technical Field

[0001] This utility model relates to the field of spotting device technology, and more specifically, to a multi-channel array spotting device for pharmaceutical testing. Background Technology

[0002] In pharmaceutical testing, it is often necessary to accurately add drug samples, biological samples (such as blood, tissue fluid extracts, etc.), reagents, etc., to specific detection carriers, such as thin-layer plates, microplates, test strips, and membranes. Spotting devices, with their sophisticated mechanical structure and control system, can precisely control the volume and position of the droplets for each spotting, ensuring that the sample falls accurately at the target site. This avoids problems such as inaccurate addition or positional deviations caused by unstable human operation, laying the foundation for accurate subsequent detection.

[0003] Existing spotting devices are generally divided into manual and automatic spotting. Manual spotting can only spot one point at a time, which is inefficient and labor-intensive. Automatic spotting devices, through multi-channel design, can spot multiple points in an array at a time. However, existing multi-channel spotting devices have poor operability because the spacing between the points is not easy to control and adjust. In view of this, we propose a multi-channel array spotting device for pharmaceutical testing. Utility Model Content

[0004] The purpose of this invention is to overcome the shortcomings of the existing technology, adapt to practical needs, and provide a multi-channel array spotting device for pharmaceutical testing, so as to solve the technical problems of inconvenient adjustment of the spot spacing and poor operability of the current multi-channel spotting.

[0005] To solve the above technical problems, this utility model provides the following technical solution: a multi-channel array spotting device for pharmaceutical testing, comprising a base plate, a frame, a shunt tube, a sliding frame, and a positioning cylinder. A placement platform is provided in the middle of the upper end face of the base plate. Supports are fixed at both ends of the upper end face of the base plate, and connecting frames are installed at the upper ends of the supports. The two connecting frames are connected by a top plate. The frame is located below the connecting frames. Sliding grooves are provided on both sides of both ends of the frame. The sliding frame is slidably installed in the sliding grooves at the corresponding ends of the frame. Spotting heads are fixedly installed at both lower ends of the shunt tube, and the spotting heads are inserted into the corresponding positioning cylinders.

[0006] In use, this invention is powered by an external power supply. The operator starts the device via an external control device, places the test carrier on the placement platform, and starts the pump connected to the outer end of the shunt tube to introduce the sample into the sampling head. The sampling head then spots the sample onto the corresponding point on the test carrier. The screw thread drives the sliding frame to synchronously move the positioning cylinder, which in turn moves the inner sampling head. This design allows adjustment of the distance between the two sampling heads, thus adjusting the sampling point. When the required sample volume is large, the liquid expansion surface increases, necessitating an increase in the distance between adjacent sampling positions. The starting motor drives the pump via the drive shaft. The frame rotates, causing the sampling head to deflect. Through rotation and spacing adjustment, an array-style sampling design is achieved. This structure enables multi-channel array-style sampling, and the sampling spacing is adjustable to ensure high practicality. The sampling head is inserted into the positioning cylinder, and then a 90-degree rotation of the sampling head allows the locking bar to enter the locking sleeve for connection and positioning. The position of the diversion tube is limited by the limiting port. The easily disassembled structural design allows the sampling components to be separated when sampling different samples, avoiding cross-contamination. At the same time, the frame is connected to the drive shaft by a bolt structure, which can be separated and disassembled for easy maintenance of the device.

[0007] Preferably, a limiting port is provided on one side of the connecting frame, and the limiting port is adapted to the diversion pipe. After the inner end of the connecting frame is inserted, it is fixed to the side opening of the top plate by bolts.

[0008] Preferably, a motor is installed on the upper surface of the top plate, and a connection interface is provided in the middle of the upper surface of the frame, and the output shaft of the motor is inserted into the connection interface and fixed by bolts.

[0009] Preferably, a lead screw is rotatably installed in the sliding groove, the sliding frame has an arc end in the middle and sliding ends at both ends, and the sliding ends are slidably installed in the corresponding sliding groove, and the lead screw thread passes through the corresponding sliding end.

[0010] Preferably, there are two positioning cylinders, and the two positioning cylinders are slidably installed in the slots at both ends of the frame, and the positioning cylinders are adapted to the sampling head.

[0011] Preferably, the arc-shaped end of the sliding frame is fixedly installed on the outside of the positioning cylinder by bolts, and locking sleeves are provided on both sides of the upper end of the positioning cylinder. Locking bars are provided on both sides of the upper end of the sampling head, and the locking bars are slidably engaged in the locking sleeves.

[0012] Compared with the prior art, the beneficial effects of this utility model are:

[0013] 1. This utility model designs a frame to place the detection carrier on a placement platform. The pump connected to the outer end of the diversion tube is activated to introduce the sample into the spotting head. The spotting head spots the sample onto the corresponding point on the detection carrier. A screw thread drives the sliding frame to simultaneously move the positioning cylinder, which in turn moves the inner spotting head. This design allows for adjustment of the distance between the two spotting heads, thus adjusting the spotting position. When the sample volume is large, the liquid expansion surface increases, necessitating an increase in the distance between adjacent spotting positions. A motor drives the frame to rotate via a drive shaft, which in turn causes the spotting head to deflect. This rotation and spacing adjustment design achieves an array-style spotting design. The above structure enables multi-channel array-style spotting, while also allowing for adjustable spotting spacing, ensuring strong practicality.

[0014] 2. This utility model also features a positioning cylinder with the sampling head inserted inside. By rotating the sampling head 90 degrees, the locking bar enters the locking sleeve to complete the connection and positioning. The position of the diversion tube is limited by the limiting port. The structural design allows for easy disassembly, enabling the sampling components to be separated when sampling different samples to avoid cross-contamination. At the same time, the frame is connected to the drive shaft by a bolt structure, which allows for easy disassembly and maintenance of the device. Attached Figure Description

[0015] Figure 1 This is a schematic diagram of the main structure of this utility model;

[0016] Figure 2 This is a schematic diagram of the connecting frame structure of this utility model;

[0017] Figure 3 This is a schematic diagram of the unfolded structure of this utility model;

[0018] Figure 4 This is a schematic diagram of the sliding frame structure of this utility model.

[0019] The following are the labels in the diagram: 1. Bracket; 2. Base plate; 201. Placement platform; 3. Frame; 301. Sliding groove; 302. Connecting interface; 303. Lead screw; 4. Top plate; 401. Motor; 5. Diverter pipe; 6. Connecting frame; 601. Limiting port; 7. Sliding frame; 701. Arc end; 702. Sliding end; 8. Positioning cylinder; 801. Locking sleeve; 9. Spotting head; 901. Locking strip. Detailed Implementation

[0020] like Figures 1 to 3As shown, this utility model relates to a multi-channel array spotting device for pharmaceutical testing, comprising a base plate 2, a frame 3, a shunt tube 5, a sliding frame 7, and a positioning cylinder 8. A placement platform 201 is provided at the middle of the upper surface of the base plate 2. Supports 1 are fixed at both ends of the upper surface of the base plate 2, and connecting frames 6 are installed at the upper ends of the supports 1. The two connecting frames 6 are connected by a top plate 4. The frame 3 is located below the connecting frames 6. A limiting port 601 is opened on one side of the connecting frame 6, and the limiting port 601 is adapted to the shunt tube 5. The inner end of the connecting frame 6 is inserted and fixed to the side opening of the top plate 4 by bolts. A motor 401 is installed on the upper surface of the top plate 4. A connection interface 302 is opened at the middle of the upper surface of the frame 3, and the output shaft of the motor 401 is inserted into the connection interface 302 and fixed by bolts. The detection carrier... The sample is placed on the placement platform 201. The pump body connected to the outer end of the diversion pipe 5 is started to introduce the sample into the sampling head 9. The sampling head 9 spots the sample onto the corresponding point on the detection carrier. The screw 303 is started to drive the sliding frame 7 to move the positioning cylinder 8 synchronously. The positioning cylinder 8 synchronously moves the inner sampling head 9. Through the above design, the distance between the two sampling heads 9 can be adjusted to complete the adjustment of the sampling point. When the sample demand is large, the expansion surface of the liquid will increase. Therefore, it is necessary to increase the distance between the connected sampling positions. The motor 401 is started to drive the frame 3 to rotate through the drive shaft. The frame 3 drives the sampling head 9 to deflect. Through the design of rotation and adjustment of distance, the array-type sampling design is completed. The above structure completes the multi-channel array-type sampling. At the same time, the sampling distance can be adjusted to ensure strong practicality.

[0021] like Figures 2 to 4As shown, this utility model relates to a multi-channel array sampling device for pharmaceutical testing, comprising a base plate 2, a frame 3, a shunt tube 5, a sliding frame 7, and a positioning cylinder 8. Sliding grooves 301 are provided on both sides of both ends of the frame 3. The sliding frame 7 is slidably installed in the corresponding sliding grooves 301 of the frame 3. A lead screw 303 is rotatably installed in the sliding groove 301. The sliding frame 7 has an arc-shaped end 701 in the middle and sliding ends 702 at both ends, with the sliding ends 702 slidably installed in the corresponding sliding grooves 301. The lead screw 303 is threaded through the corresponding sliding end 702. Sampling heads 9 are fixedly installed at both lower ends of the shunt tube 5, and the sampling heads 9 are inserted into the corresponding positioning cylinders 8. There are two positioning cylinders 8, and the two positioning cylinders 8 are slidably installed on both sides of the frame 3. Inside the slot at the end, the positioning cylinder 8 is adapted to the sampling head 9. The arc end 701 of the sliding frame 7 is fixedly installed on the outside of the positioning cylinder 8 by bolts. Locking sleeves 801 are provided on both sides of the upper end of the positioning cylinder 8. Locking bars 901 are provided on both sides of the upper end of the sampling head 9. The locking bars 901 are slidably engaged in the locking sleeves 801. The sampling head 9 is inserted into the positioning cylinder 8. Then, by rotating the sampling head 9 ninety degrees, the locking bars 901 are moved into the locking sleeves 801 to complete the connection and positioning. The position of the diversion tube 5 is limited by the limiting port 601. The structural design of easy disassembly allows the sampling components to be separated when sampling different samples to avoid mutual contamination. At the same time, the frame 3 is connected to the drive shaft by bolt structure, which can be separated and disassembled to facilitate the inspection and maintenance of the device.

[0022] Working Principle: This embodiment provides a multi-channel array spotting device for pharmaceutical testing. In use, it is powered by an external power supply. The operator starts the device via an external control device, places the test carrier on the placement platform 201, and starts the pump body connected to the outer end of the shunt tube 5 to guide the sample into the spotting head 9. The spotting head 9 spots the sample onto the corresponding point on the test carrier. The starting screw 303 drives the sliding frame 7 to simultaneously move the positioning cylinder 8, which in turn moves the inner spotting head 9. Through this design, the distance between the two spotting heads 9 can be adjusted to regulate the spotting position. When the required sample volume is large, the liquid expansion surface increases, thus requiring an increased distance between connected spotting positions. The starting motor 401 drives the frame 3 to rotate via the drive shaft, causing the spotting head 9 to deflect. The spotting head 9 is inserted into the positioning cylinder 8. Then, by rotating the spotting head 9 9 by 90 degrees, the locking strip 901 enters the locking sleeve 801 to complete the connection and positioning. The position of the shunt tube 5 is limited by the limiting port 601.

[0023] The embodiments disclosed herein are preferred embodiments, but are not limited thereto. Those skilled in the art can readily grasp the spirit of this utility model based on the above embodiments and make different extensions and variations. However, as long as they do not depart from the spirit of this utility model, they are all within the protection scope of this utility model.

Claims

1. A multi-channel array spotting device for pharmaceutical testing, comprising a base plate (2), a frame (3), a shunt tube (5), a sliding frame (7), and a positioning cylinder (8), characterized in that: The upper end face of the base plate (2) is provided with a placement platform (201) in the middle. Both ends of the upper end face of the base plate (2) are fixed with brackets (1), and the upper end of the brackets (1) is equipped with a connecting frame (6). The two connecting frames (6) are connected by a top plate (4). The frame (3) is located under the connecting frame (6). Both sides of the frame (3) are provided with sliding grooves (301). The sliding frame (7) is slidably installed in the sliding groove (301) at the corresponding end of the frame (3). The two lower ends of the diversion pipe (5) are fixedly installed with a sampling head (9), and the sampling head (9) is inserted into the corresponding positioning cylinder (8).

2. The multi-channel array spotting device for pharmaceutical testing according to claim 1, characterized in that: The connecting frame (6) has a limiting port (601) on one side, and the limiting port (601) is compatible with the diversion pipe (5). After the inner end of the connecting frame (6) is inserted, it is fixed to the side opening of the top plate (4) by bolts.

3. The multi-channel array spotting device for pharmaceutical testing according to claim 2, characterized in that: A motor (401) is installed on the upper end face of the top plate (4), and a connection interface (302) is provided in the middle of the upper end face of the frame (3). The output shaft of the motor (401) is inserted into the connection interface (302) and then fixed by bolts.

4. The multi-channel array spotting device for pharmaceutical testing according to claim 3, characterized in that: A lead screw (303) is rotatably installed in the sliding groove (301). The sliding frame (7) has an arc end (701) in the middle and sliding ends (702) at both ends. The sliding ends (702) are slidably installed in the corresponding sliding groove (301). The lead screw (303) is threaded through the corresponding sliding end (702).

5. The multi-channel array spotting device for pharmaceutical testing according to claim 4, characterized in that: There are two positioning cylinders (8), and the two positioning cylinders (8) are slidably installed in the slots at both ends of the frame (3). The positioning cylinders (8) are adapted to the sampling head (9).

6. The multi-channel array spotting device for pharmaceutical testing according to claim 5, characterized in that: The arc end (701) of the sliding frame (7) is fixedly installed on the outside of the positioning cylinder (8) by bolts. Lock sleeves (801) are provided on both sides of the upper end of the positioning cylinder (8). Locking bars (901) are provided on both sides of the upper end of the sampling head (9), and the locking bars (901) are slidably engaged in the locking sleeves (801).

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