Upward rotation type screening machine for paliperidone palmitate raw material medicine

Abstract

The utility model provides a paliperidone palmitate bulk drug up-rotation type screening machine, belongs to the technical field of tablet processing and production, and aims to solve the problems that an existing paliperidone palmitate bulk drug up-rotation type screening machine is blocked in feeding, interfered by chippings and unstable in vibration supporting. Comprising a supporting base, a lifting adjusting rod, a screening machine body, a feeding port, a discharging port, a supporting assembly and a feeding assembly, and the lifting adjusting rod is connected to the top of the supporting base through a bolt; the screening machine main body is in bolted connection with the top end of the lifting adjusting rod; the feeding hole is formed in one side of the screening machine main body; the discharge hole is formed in the other side of the screening machine main body; the supporting assembly is arranged in the supporting base. The feeding assembly is arranged in the feeding port. The device has the advantages of being stable in supporting, avoiding accumulation, reducing chippings and the like.

Description

Technical Field

[0001] This utility model belongs to the field of pharmaceutical tablet processing and production technology, and more specifically, it relates to a rotary sieve tablet machine for paliperidone palmitate raw material. Background Technology

[0002] Paliperidone palmitate is a benzisoxazole antipsychotic drug. During the production of its active pharmaceutical ingredient (API), screening is necessary to ensure product quality. This screening process requires a rotary sieve screen for paliperidone palmitate API. Existing rotary sieve screens for paliperidone palmitate API typically consist of a base, support columns, and a screening box. The screening box has a feed inlet at the bottom and an internal screening mechanism. A motor drives a rotating shaft, causing the stirring blades to operate synchronously with the upward-rotating screen. A downward-rotating screen is located below. An outlet is located on one side of the equipment to achieve the classified collection of APIs with different particle sizes.

[0003] Existing application number CN202320275358.X discloses a user-friendly upward-rotating screen, comprising a screen body, a movable plate, a feed pipe, and a discharge pipe. This invention uses a control box to activate the screening and feeding assembly, ensuring stable material feeding. It solves the problem that while existing upward-rotating screens offer height adjustment to avoid bending over and facilitate use, in practice, the feed inlet is located at the bottom, causing material to accumulate at the inlet during upward dust removal. This reduces dust removal efficiency during output. While small, repeated increases in volume can alleviate this, it increases the workload for operators and reduces the screen's overall effectiveness.

[0004] Based on the above, existing rotary sieve screening machines for paliperidone palmitate raw materials tend to experience significant accumulation of raw material at the feed inlet, leading to blockages. Simultaneously, debris and powder mixed in with the raw material enter the screening machine along with it. This debris and powder can interfere with screening, clog the screen, and affect product quality. Furthermore, although the screening machine is equipped with rollers for easy movement, the continuous vibration during operation and the unstable roller support cause equipment swaying, reducing screening accuracy and posing safety hazards. Utility Model Content

[0005] To address the aforementioned technical problems, this invention provides a rotary sieve screen for paliperidone palmitate raw materials. This addresses the issues of existing rotary sieve screens for paliperidone palmitate raw materials, where raw materials tend to accumulate in large quantities at the feed inlet, leading to blockages. Simultaneously, debris and powder mixed in with the raw material enter the sieve screen along with the raw material. This debris and powder may interfere with sieving, clog the screen, and affect product quality. Furthermore, although the sieve screen is equipped with rollers for easy movement, continuous vibration during operation and unstable roller support cause equipment swaying, reducing sieving accuracy and posing safety hazards.

[0006] The purpose and efficacy of this utility model, a rotary sieve tableting machine for paliperidone palmitate raw material, are achieved by the following specific technical means:

[0007] A paliperidone palmitate raw material rotary sieving machine includes a support base, a lifting adjustment rod, a sieving machine body, a feed inlet, a discharge outlet, a support assembly, and a feeding assembly. The lifting adjustment rod is bolted to the top of the support base; the sieving machine body is bolted to the top of the lifting adjustment rod; the feed inlet is installed on one side of the sieving machine body; the discharge outlet is installed on the other side of the sieving machine body; the support assembly is disposed inside the support base; and the feeding assembly is disposed inside the feed inlet.

[0008] Furthermore, the support assembly includes: a threaded screw, an adjusting knob, and a threaded drive block. The threaded screw is rotatably connected inside the support base and is composed of threads with opposite directions at both ends. The adjusting knob is fixedly installed at one end of the threaded screw. Two sets of threaded drive blocks are provided, and the two sets of threaded drive blocks are respectively threadedly connected to both ends of the threaded screw.

[0009] Furthermore, the support assembly also includes: transmission rods, grooved connecting rods, and guide cylinders. Two pairs of transmission rods are provided, each fixedly installed on both sides of the two sets of threaded drive blocks. Two pairs of grooved connecting rods are provided, each hinged to the bottom of the two sets of threaded drive blocks. Two pairs of guide cylinders are provided, each fixedly installed at the bottom of the support base, and each pair of guide cylinders is slidably connected within grooves opened inside the two pairs of grooved connecting rods.

[0010] Furthermore, the support assembly also includes: sliding guide rails and drive racks. The sliding guide rails are provided in two sets, and the two sets of sliding guide rails are fixedly installed on both sides inside the support base. The drive racks are provided in two pairs, and the two pairs of drive racks are slidably connected inside the two sets of sliding guide rails respectively.

[0011] Furthermore, the support assembly also includes: driving threads and transmission gears. The driving threads are provided in two pairs, and the two pairs of driving threads are rotatably connected inside the two sets of sliding guide rails respectively. The transmission gears are provided in two pairs, and the two pairs of transmission gears are coaxially fixedly installed at one end of the two pairs of driving threads respectively. The transmission gears and driving racks mesh with each other.

[0012] Furthermore, the support assembly also includes: transmission blocks and movable rollers. The transmission blocks are provided in two pairs, and the two pairs of transmission blocks are respectively vertically slidably connected to the front and rear sides of the support base. The two pairs of transmission blocks are threadedly connected to the outside of the two pairs of drive threads. The movable rollers are provided in two pairs, and the two pairs of movable rollers are respectively bolted to the bottom of the two pairs of transmission blocks.

[0013] Furthermore, the feeding assembly includes a drive motor and a conveying auger, wherein the drive motor is fixedly installed at one end of the feed inlet; and the conveying auger is rotatably connected inside the feed inlet.

[0014] Furthermore, the feeding assembly also includes a perforated strainer and a collection box, wherein the perforated strainer is fixedly connected to the bottom of the feed inlet; and the collection box is snapped into the bottom of the feed inlet.

[0015] Compared with the prior art, the present invention has the following beneficial effects:

[0016] Firstly, this invention features a support assembly. Turning the adjustment knob rotates the threaded screw, which in turn drives a series of parts, causing the transmission block to lift the moving rollers and lower the support base. Simultaneously, the grooved connecting rod oscillates under the drive of the threaded drive block, and the guide cylinder slides within the groove of the grooved connecting rod, providing guidance and allowing the grooved connecting rod to unfold smoothly outwards. Thus, as the support base falls, the grooved connecting rod unfolds outwards, significantly increasing the support area of ​​the support base and greatly improving the stability of the screening machine during operation. This effectively solves the problem of unstable support caused by vibration in existing screening machines.

[0017] Secondly, this invention features a feeding assembly. When feeding is required, the drive motor is activated to rotate the conveying auger, dynamically conveying the raw material tablets in the feed inlet and preventing accumulation and blockage. During the tablet conveying process, any debris or powder carried by the tablets falls into the collection box through a perforated strainer at the bottom of the feed inlet. The collection box is snap-fitted to the bottom of the feed inlet for easy disassembly, allowing for centralized processing of debris and powder, preventing it from entering the main body of the tablet sieving machine, thus ensuring the accuracy and stability of the tablet sieving operation.

[0018] This invention has the advantages of stable support, avoiding accumulation, and reducing debris. It greatly increases the support area of ​​the support base, significantly improves the stability of the screening machine during operation, and retracts the grooved connecting rod while the moving rollers fall and unfold, which facilitates movement, reduces storage volume, and reduces the accumulation of raw materials. Attached Figure Description

[0019] Figure 1 This is a schematic diagram of the structure of this utility model.

[0020] Figure 2 This is a schematic diagram of the structure of this utility model.

[0021] Figure 3 This is a schematic diagram of the structure of this utility model.

[0022] Figure 4 This is a schematic diagram of the structure of this utility model.

[0023] Figure 5 This is a schematic diagram of the structure of this utility model.

[0024] Figure 6 This is a schematic diagram of the structure of this utility model.

[0025] In the diagram, the correspondence between component names and drawing numbers is as follows:

[0026] 1. Support base; 101. Adjustment knob; 102. Threaded screw; 103. Threaded drive block; 1031. Transmission rod; 104. Grooved connecting rod; 105. Guide cylinder; 106. Sliding guide rail; 1061. Drive rack; 1062. Drive thread; 1063. Transmission gear; 107. Moving roller; 1071. Transmission block; 2. Lifting adjustment rod; 3. Screening machine body; 4. Feed inlet; 401. Drive motor; 402. Conveying auger; 403. Perforated perforated plate; 404. Collection box; 5. Discharge outlet. Detailed Implementation

[0027] The embodiments of this utility model will be described in further detail below with reference to the accompanying drawings and examples. The following examples are for illustrative purposes only and should not be construed as limiting the scope of this utility model.

[0028] Example 1:

[0029] As attached Figure 1 To be continued Figure 6 As shown:

[0030] This utility model provides a rotary sieve screening machine for paliperidone palmitate raw material, including a support base 1, a lifting adjustment rod 2, a sieve screening machine body 3, a feed inlet 4, a discharge outlet 5, and a support assembly. The lifting adjustment rod 2 is bolted to the top of the support base 1; the sieve screening machine body 3 is bolted to the top of the lifting adjustment rod 2; the feed inlet 4 is installed on one side of the sieve screening machine body 3; the discharge outlet 5 is installed on the other side of the sieve screening machine body 3; and the support assembly is located inside the support base 1.

[0031] The support assembly includes a threaded screw 102, an adjusting knob 101, and a threaded drive block 103. The threaded screw 102 is rotatably connected inside the support base 1 and is composed of threads with opposite directions at both ends. The adjusting knob 101 is fixedly installed at one end of the threaded screw 102. Two sets of threaded drive blocks 103 are provided, and the two sets of threaded drive blocks 103 are respectively threadedly connected to both ends of the threaded screw 102.

[0032] The support assembly also includes: transmission rods 1031, grooved connecting rods 104, and guide cylinders 105. Two pairs of transmission rods 1031 are provided, and the two pairs of transmission rods 1031 are respectively fixedly installed on both sides of the two sets of threaded drive blocks 103. Two pairs of grooved connecting rods 104 are provided, and the two pairs of grooved connecting rods 104 are respectively hinged to the bottom of the two sets of threaded drive blocks 103. Two pairs of guide cylinders 105 are provided, and the two pairs of guide cylinders 105 are fixedly installed at the bottom of the support base 1. The two pairs of guide cylinders 105 are respectively slidably connected in the grooves opened inside the two pairs of grooved connecting rods 104.

[0033] The support assembly also includes: a sliding guide rail 106 and a drive rack 1061. Two sets of sliding guide rails 106 are provided, and the two sets of sliding guide rails 106 are fixedly installed on both sides inside the support base 1. Two pairs of drive racks 1061 are provided, and the two pairs of drive racks 1061 are slidably connected inside the two sets of sliding guide rails 106 respectively.

[0034] The support assembly also includes: a drive thread 1062 and a transmission gear 1063. The drive thread 1062 is provided in two pairs, and the two pairs of drive threads 1062 are rotatably connected inside the two sets of sliding guide rails 106 respectively. The transmission gear 1063 is provided in two pairs, and the two pairs of transmission gears 1063 are coaxially fixedly installed at one end of the two pairs of drive threads 1062 respectively. The transmission gear 1063 and the drive rack 1061 mesh with each other.

[0035] The support assembly also includes: transmission blocks 1071 and movable rollers 107. Two pairs of transmission blocks 1071 are provided, and the two pairs of transmission blocks 1071 are vertically slidably connected to the front and rear sides of the support base 1, respectively. The two pairs of transmission blocks 1071 are threadedly connected to the outside of two pairs of drive threads 1062. Two pairs of movable rollers 107 are provided, and the two pairs of movable rollers 107 are bolted to the bottom of the two pairs of transmission blocks 1071.

[0036] The specific usage and function of this embodiment are as follows:

[0037] When the main body 3 of the sieve machine needs to sieve raw drug tablets, turn the adjustment knob 101. The adjustment knob 101 drives the threaded screw 102 to rotate. Because the threads at both ends of the threaded screw 102 rotate in opposite directions, during its rotation, it will drive two sets of threaded drive blocks 103 to move relative to each other. The relative movement of the two sets of threaded drive blocks 103 pulls two pairs of transmission rods 1031 to move synchronously. The movement of the transmission rods 1031 drives the drive rack 1061 to slide inside the sliding guide rail 106. The movement of the drive rack 1061 drives the transmission gear 1063 to rotate. The rotation of the transmission gear 1063 drives the drive thread 1062 to rotate. The rotation of the drive thread 1062 drives the transmission block 1071 to rise and fall through the threaded structure. The rise of the transmission block 1071 drives the moving roller 107 to rise, causing the support base 1 to fall.

[0038] Simultaneously, the relative movement of the two sets of threaded drive blocks 103 causes the grooved connecting rod 104 to swing. During the swinging process of the grooved connecting rod 104, the guide cylinder 105 slides within the groove inside the grooved connecting rod 104. The guide cylinder 105 guides the grooved connecting rod 104 during its swing, ensuring that the grooved connecting rod 104 unfolds smoothly outward. Therefore, as the support base 1 falls, the grooved connecting rod 104 unfolds outward, significantly increasing the support area of ​​the support base 1 and greatly improving the stability of the screening machine during operation.

[0039] Example 2:

[0040] Based on Example 1, such as Figures 1 to 6 As shown, it also includes: a feeding assembly, which is disposed inside the feeding port 4.

[0041] The feeding assembly includes a drive motor 401 and a conveying auger 402. The drive motor 401 is fixedly installed at one end of the feed inlet 4; the conveying auger 402 is rotatably connected inside the feed inlet 4.

[0042] The feeding assembly also includes a perforated strainer 403 and a collection box 404. The perforated strainer 403 is fixedly connected to the bottom of the feed inlet 4; the collection box 404 is snapped into the bottom of the feed inlet 4.

[0043] The specific usage and function of this embodiment are as follows:

[0044] When feeding material into the tablet sieve machine through inlet 4, the drive motor 401 is started. After the motor is powered on, it drives the conveying auger 402 to rotate, dynamically conveying the raw tablets in inlet 4. This effectively prevents the raw tablets from accumulating at the inlet, thus avoiding blockages.

[0045] During the process of conveying the raw material tablets through the feed inlet 4, the fragments and powders carried by them will naturally fall into the collection box 404 below through the perforated strainer 403 at the bottom of the feed inlet 4. The collection box 404 is installed at the bottom of the feed inlet 4 by a snap-fit ​​method, which not only has a good effect on collecting fragments and powders, but also makes it easy to disassemble. Operators can easily remove the collection box to centrally process the fragments and powders stored inside, preventing fragments and powders from entering the body 3 of the tablet screening machine.

[0046] The following points should be noted in this article:

[0047] 1. The accompanying drawings of this embodiment only involve the structures involved in this embodiment; other structures can refer to the general design.

[0048] 2. Where there is no conflict, this embodiment and the features in the embodiment can be combined with each other to obtain new embodiments.

[0049] The above are merely specific implementations of this embodiment, but the protection scope of this embodiment is not limited thereto. Any variations or substitutions that can be easily conceived by those skilled in the art within the technical scope disclosed in this embodiment should be included within the protection scope of this embodiment. Therefore, the protection scope of this embodiment should be determined by the protection scope of the claims.

Claims

1. A rotary sieve screening machine for paliperidone palmitate raw material, characterized in that: This paliperidone palmitate raw material rotary sieve includes a support base (1), a lifting adjustment rod (2), a sieve body (3), a feed inlet (4), a discharge outlet (5), a support assembly, and a feed assembly. The lifting adjustment rod (2) is bolted to the top of the support base (1); the sieve body (3) is bolted to the top of the lifting adjustment rod (2); the feed inlet (4) is installed on one side of the sieve body (3); the discharge outlet (5) is installed on the other side of the sieve body (3); and the support assembly is located inside the support base (1). The support assembly includes: a threaded screw (102), an adjustment knob (101), and a threaded drive block (103). The threaded screw (102) is rotatably connected inside the support base (1). The threaded screw (102) is composed of threads with opposite directions at both ends. The adjustment knob (101) is fixedly installed at one end of the threaded screw (102). Two sets of threaded drive blocks (103) are provided, and the two sets of threaded drive blocks (103) are respectively connected to the two ends of the threaded screw (102) by threads. The feeding assembly is located inside the feed inlet (4).

2. The palmitate paliperidone raw material rotary sieve screening machine as described in claim 1, characterized in that: The support assembly further includes: transmission rods (1031), grooved connecting rods (104), and guide cylinders (105). There are two pairs of transmission rods (1031), which are fixedly installed on both sides of the two sets of threaded drive blocks (103). There are two pairs of grooved connecting rods (104), which are hinged to the bottom of the two sets of threaded drive blocks (103). There are two pairs of guide cylinders (105), which are fixedly installed at the bottom of the support base (1). The two pairs of guide cylinders (105) are slidably connected in the grooves opened inside the two pairs of grooved connecting rods (104).

3. The palmitate paliperidone raw material rotary sieve screening machine as described in claim 2, characterized in that: The support assembly also includes: a sliding guide rail (106) and a drive rack (1061). The sliding guide rail (106) is provided in two sets, and the two sets of sliding guide rails (106) are fixedly installed on both sides inside the support base (1). The drive rack (1061) is provided in two pairs, and the two pairs of drive racks (1061) are slidably connected inside the two sets of sliding guide rails (106).

4. The palmitate paliperidone raw material rotary sieve screening machine as described in claim 2, characterized in that: The support assembly also includes: a drive thread (1062) and a transmission gear (1063). The drive thread (1062) has two pairs, and the two pairs of drive threads (1062) are rotatably connected inside the two sets of sliding guide rails (106). The transmission gear (1063) has two pairs, and the two pairs of transmission gears (1063) are coaxially fixedly installed at one end of the two pairs of drive threads (1062). The transmission gear (1063) and the drive rack (1061) mesh with each other.

5. The palmitate paliperidone raw material rotary sieve screening machine as described in claim 2, characterized in that: The support assembly further includes: a transmission block (1071) and a movable roller (107). The transmission block (1071) is provided in two pairs, and the two pairs of transmission blocks (1071) are vertically slidably connected to the front and rear sides of the support base (1). The two pairs of transmission blocks (1071) are threadedly connected to the outside of two pairs of drive threads (1062). The movable roller (107) is provided in two pairs, and the two pairs of movable rollers (107) are bolted to the bottom of the two pairs of transmission blocks (1071).

6. The paliperidone palmitate raw material rotary sieve screening machine as described in claim 1, characterized in that: The feeding assembly includes a drive motor (401) and a conveying auger (402). The drive motor (401) is fixedly installed at one end of the feed inlet (4). The conveying auger (402) is rotatably connected inside the feed inlet (4).

7. The palmitate paliperidone raw material rotary sieve screening machine as described in claim 6, characterized in that: The feeding assembly also includes a perforated strainer (403) and a collection box (404), wherein the perforated strainer (403) is fixedly connected to the bottom of the feed inlet (4); and the collection box (404) is snapped into the bottom of the feed inlet (4).

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