Stem cell storage test tube heat preservation device
By designing a heat preservation device for stem cell storage tubes, and utilizing an automatic retrieval box and a non-coaxial storage rack structure, the heat exchange of the storage tank is reduced, solving the problem of temperature stability in existing technologies, and improving the stability of stem cells and space utilization.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- HENAN CELL THERAPY GRP CO LTD
- Filing Date
- 2025-05-16
- Publication Date
- 2026-05-08
AI Technical Summary
In existing technologies, opening the sealed lid of a storage box or container can affect the temperature stability inside the storage box or container, thereby affecting the stability of other stem cells.
A stem cell storage tube insulation device was designed, including a storage tank, a detachable outer material extraction cover, a rotatable storage rack, a material extraction tube, and material extraction claws. The automatic extraction and placement of the storage tank reduces the opening space of the storage tank. The non-coaxial design of the outer rack and the inner rack improves space utilization, and the sealing of the inner material extraction cover reduces heat exchange.
This effectively reduces heat exchange between the storage tank and the outside environment, maintains the stability of stem cells, improves the space utilization of the storage tank, and reduces the impact on other stem cells.
Smart Images

Figure CN224211603U_ABST
Abstract
Description
Technical Field
[0001] This utility model belongs to the field of stem cell storage technology and relates to a stem cell storage test tube insulation device. Background Technology
[0002] Stem cells are a type of pluripotent cell with self-renewal capacity. Stem cells remain in an undifferentiated state and have the ability to proliferate. They can differentiate into various functional cells or tissues and organs. After being isolated and cultured from different human tissues, stem cells are cryopreserved at -196°C so that they can be revived and reinfused into patients when needed in clinical practice to achieve the purpose of treating diseases.
[0003] Currently, stem cell storage primarily involves placing stem cells in storage tanks or containers equipped with liquid nitrogen. Large storage tanks or containers hold a significant number of stem cells. Opening the sealed lid during storage or retrieval may affect the temperature stability within the tank or container, potentially impacting the stability of other stored stem cells. Utility Model Content
[0004] To address the aforementioned problems, this invention proposes a stem cell storage test tube insulation device, which effectively solves the problems in the prior art.
[0005] To achieve the above objectives, the technical solution adopted by this utility model is as follows:
[0006] A stem cell storage test tube insulation device, comprising:
[0007] A storage tank connected to a liquid nitrogen cooling system, and a removable external material handling cover is provided at the top of the storage tank;
[0008] A storage rack is rotatably installed inside the storage tank. The storage tank is fixedly connected to a first motor, the output end of which is connected to the storage rack. The storage rack has multiple layers, and each layer has multiple placement slots arranged in a circumferential array.
[0009] A pick-and-place rack is fixedly installed on the upper end of the storage tank;
[0010] A material picking tube is slidably mounted on the picking and placing frame. The lower end of the material picking tube passes through the upper end of the storage tank. The picking and placing frame is fixedly connected to a first linear drive, and the output end of the first linear drive is fixedly connected to the material picking tube.
[0011] The material receiving rail assembly is fixedly installed at the lower end of the material receiving tube. The material receiving rail assembly is a ball screw mechanism. A second motor is provided at the upper end of the material receiving tube, and the output end of the second motor is connected to the material receiving rail assembly.
[0012] The material handling claw is fixedly installed at the output end of the material handling rail assembly.
[0013] The stem cell storage tube is placed in the placement box, and the placement box is placed in the placement slot.
[0014] Optionally, the storage rack includes an external rack and an internal rack, both rotatably mounted on the storage tank, with the material picking tube located between the external rack and the internal rack. A third motor is fixedly mounted on the first linear drive output end, and the material picking tube is mounted on the output end of the third motor.
[0015] Optionally, the built-in frame and the external frame are not coaxial, and the side of the built-in frame away from the material handling rail assembly is closer to the external frame.
[0016] Optionally, the upper end of the storage rack is provided with a positioning through hole corresponding to the bayonet position, and the storage tank is slidably mounted with a conical positioning rod, which is connected to a second linear drive.
[0017] Optionally, an inner material-retrieving cover is fixedly installed at the lower end of the material-retrieving claw, and the inner material-retrieving cover seals the storage tank from the inner side of the upper end of the storage tank.
[0018] Optionally, positioning grooves are provided on both sides of the bottom of the placement box, and positioning plugs are provided at the corresponding positions of the placement slot and the picking claw.
[0019] Optionally, a positioning ring is fixedly installed at the first linear drive output end, and the material picker tube is rotatably installed inside the positioning ring. A limiting protrusion is fixedly provided on the inner side of the positioning ring, and a limiting arc groove is opened on the outer side of the material picker tube.
[0020] Compared with the prior art, the present invention has the following beneficial effects:
[0021] 1. By setting up a material picking tube and picking claw that can automatically pick up and put in the placement box, the corresponding placement box can be picked up and put in through the outer material picking cover, reducing the opening space of the storage tank, thereby reducing the heat exchange between the storage tank and the outside world, and thus reducing the impact on the stability of other stored stem cells;
[0022] 2. By setting up external and internal frames, the material picking tube can rotate to face different placement slots for picking and placing, improving the space utilization rate inside the storage tank. Furthermore, by setting the internal and external frames non-coaxially, the internal frame is located at a position with a larger distance between the material picking tube and the external frame, thereby maximizing the diameter of the internal frame and increasing the number of placement slots on the internal frame, further improving the space utilization rate inside the storage tank. Attached Figure Description
[0023] Figure 1This is a schematic diagram of the overall structure of an embodiment of the present utility model;
[0024] Figure 2 This is a schematic diagram of the storage rack portion according to an embodiment of the present utility model;
[0025] Figure 3 This is a schematic diagram of the structure of the picking claw part in an embodiment of the present utility model;
[0026] Figure 4 yes Figure 1 Enlarged schematic diagram of part B;
[0027] Figure 5 yes Figure 1 An enlarged schematic diagram of part A in the middle;
[0028] Figure 6 yes Figure 5 An enlarged schematic diagram of section C.
[0029] Reference numerals: 1. Storage tank; 11. Outer material pick-up cover; 12. Inner material pick-up cover; 2. Storage rack; 201. Placement slot; 202. External rack; 203. Internal rack; 204. Positioning through hole; 205. Conical positioning rod; 206. Second linear drive; 21. First motor; 31. Pick-up and placement rack; 32. Pick-up tube; 321. First linear drive; 322. Third motor; 33. Pick-up rail assembly; 331. Second motor; 34. Pick-up claw; 4. Placement box; 41. Positioning groove; 42. Positioning plug; 43. Positioning ring; 431. Limiting protrusion; 432. Limiting arc groove. Detailed Implementation
[0030] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.
[0031] Please see Figures 1 to 3This invention discloses a stem cell storage test tube insulation device, comprising a storage tank 1 connected to a liquid nitrogen cooling system, a detachable outer material-retrieving cover 11 at the upper end of the storage tank 1, a storage rack 2 rotatably mounted inside the storage tank 1, a first motor 21 fixedly connected to the storage tank 1, the output end of the first motor 21 connected to the storage rack 2, the storage rack 2 having multiple layers, each layer having multiple placement slots 201 arranged in a circumferential array, a pick-and-place rack 31 fixedly mounted at the upper end of the storage tank 1, and a material-retrieving tube 3 slidably mounted on the pick-and-place rack 31. 2. The lower end of the material picking tube 32 passes through the upper end of the storage tank 1. The picking and placing rack 31 is fixedly connected to the first linear drive 321. The output end of the first linear drive 321 is fixedly connected to the material picking tube 32. The lower end of the material picking tube 32 is fixedly installed with a material picking rail assembly 33, which is a ball screw mechanism. The upper end of the material picking tube 32 is provided with a second motor 331. The output end of the second motor 331 is connected to the material picking rail assembly 33. The output end of the material picking rail assembly 33 is fixedly installed with a material picking claw 34. The placement slot 201 holds a placement box 4, and the stem cell storage test tube is placed in the placement box 4.
[0032] Specifically, a rotatable storage rack 2 is provided inside the storage tank 1. The storage rack 2 is provided with a placement slot 201 for placing the placement box 4. A material picking tube 32 driven by a first linear drive 321 is provided on the storage tank 1. The end of the material picking tube 32 is provided with a material picking rail assembly 33 that moves radially along the storage tank 1. The material picking rail assembly 33 drives the material picking claw 34 to engage with the placement box 4, and is driven by the first linear drive 321 to rise to the position of the outer material picking cover 11. The placement box 4 can be removed by removing the outer material picking cover 11.
[0033] In this way, by setting up the material picking tube 32 and material picking claw 34 that can automatically pick up and put in the placement box 4, the corresponding placement box 4 can be picked up and put in through the position of the outer material picking cover 11, reducing the opening space of the storage tank 1, thereby reducing the heat exchange between the storage tank 1 and the outside world, and thus reducing the impact on the stability of other stored stem cells.
[0034] In some feasible methods, the storage tank 1 is a circular insulated tank. Cooling liquid nitrogen is installed at the bottom of the storage tank 1, and a storage rack 2 is installed at the top. The liquid nitrogen cooling system supplies liquid nitrogen to the storage tank 1. The liquid nitrogen cooling system and the storage tank 1 are part of the prior art and will not be described in detail here.
[0035] The storage rack 2 is cylindrical, and the placement slot 201 is a triangular prism block with a rectangular groove at the top. The placement box 4 is placed in the rectangular groove. The picking claw 34 has the same shape as the placement slot 201. The placement box 4 has at least one corresponding placement hole according to the actual test tube size. There are multiple placement slots 201 arranged in a circumferential array, and multiple layers of placement slots 201 are arranged in an axial array along the storage rack 2.
[0036] The pick-and-place frame 31 is C-shaped, with a screw rotatably mounted inside. A first linear drive 321 is a drive motor, and its output end is fixedly connected to the screw. A sliding block is threaded onto the screw. The pick-and-place tube 32 is mounted on the sliding block via a bearing seat. Both ends of the pick-and-place tube 32 are equipped with bevel gearboxes, each containing two rotatably mounted bevel gears. The two bevel gearboxes are connected by a connecting shaft. The upper bevel gearbox of the pick-and-place tube 32 is connected to a second motor 331, and the lower bevel gearbox is connected to the pick-and-place rail assembly 33. The structure of the pick-and-place rail assembly 33 is partially the same as that of the pick-and-place frame 31.
[0037] As one specific embodiment of the stem cell storage test tube insulation device provided in the application, please refer to Figure 2 The storage rack 2 includes an external rack 202 and an internal rack 203 that are rotatably mounted on the storage tank 1. The material picking tube 32 is located between the external rack 202 and the internal rack 203. A third motor 322 is fixedly mounted on the output end of the first linear drive 321, and the material picking tube 32 is mounted on the output end of the third motor 322.
[0038] Overall, by setting up an external frame 202 and an internal frame 203, the material picking tube 32 can be rotated to be placed or picked up in different placement slots 201, thereby improving the space utilization rate inside the storage tank 1.
[0039] Furthermore, the built-in frame 203 and the external frame 202 are not coaxial, with the built-in frame 203 located away from the material handling rail assembly 33 and close to the external frame 202.
[0040] It should be understood that by setting the built-in frame 203 and the external frame 202 non-coaxially, the built-in frame 203 is located at a position with a large distance between the material picking tube 32 and the external frame 202, thereby making the diameter of the built-in frame 203 as large as possible, increasing the number of slots 201 set on the built-in frame 203, and further improving the space utilization rate inside the storage tank 1.
[0041] Further, please refer to Figure 5 and Figure 6 The first linear drive 321 has a fixed positioning ring 43 at its output end. The material picker tube 32 is rotatably installed inside the positioning ring 43. A limit protrusion 431 is fixedly provided on the inner side of the positioning ring 43, and a limit arc groove 432 is opened on the outer side of the material picker tube 32.
[0042] It should be understood that by setting the limiting protrusion 431 and the limiting arc groove 432, the stopping position of the rotating material picking tube 32 is restricted, reducing the situation where the rotating material picking tube 32 rotates too much and makes it inconvenient to pick up the placement box 4.
[0043] In some feasible configurations, the built-in frame 203 is rotatably mounted at both ends of the storage tank 1. A gear is mounted on the upper end of the built-in frame 203, and an internal gear ring is mounted on the upper end of the external frame 202. The gear and the internal gear ring mesh with the same drive gear, which is connected to the first motor 21. A positioning ring 43 is fixedly mounted on the sliding block of the pick-and-place rack 31. A rectangular block-shaped limiting protrusion 431 is provided inside the positioning ring 43, and a limiting arc groove 432 is set according to the required rotation angle. Further, electrode plates can be provided on the contact surfaces of the limiting protrusion 431 and the limiting arc groove 432. The stop position of the third motor 322 is controlled by the contact signal of the electrode plates. The third motor 322 is fixedly mounted on the sliding block, and its output end is fixedly connected to the upper end of the bevel gearbox.
[0044] As one specific embodiment of the stem cell storage test tube insulation device provided in the application, please refer to Figure 1 and Figure 4 The upper end of the storage rack 2 is provided with a positioning through hole 204 corresponding to the position of the bayonet 201. The storage tank 1 is slidably mounted with a conical positioning rod 205, and the conical positioning rod 205 is connected to a second linear drive 206.
[0045] It should be understood that by setting the positioning through hole 204 and the conical positioning rod 205, it is convenient to rotate the storage rack 2 to a suitable position and then further calibrate the position by pressing down the conical positioning rod 205, so as to facilitate the placement and removal of the box 4.
[0046] In some feasible configurations, the second linear drive 206 is an electric actuator.
[0047] As one specific embodiment of the stem cell storage test tube insulation device provided in the application, please refer to Figure 1 and Figure 3 An inner material handling cover 12 is fixedly installed at the lower end of the material handling claw 34, and the inner material handling cover 12 seals the storage tank 1 from the inner side of the upper end of the storage tank 1.
[0048] It should be understood that by setting the inner material retrieval cover 12, when taking out or placing the storage box 4, the inner material retrieval cover 12 seals from the bottom of the upper end of the storage tank 1, further reducing the impact on the stability of other stored stem cells during the taking out or placing process.
[0049] In some feasible ways, the inner material handling cover 12 is set according to the shape of the material handling port at the upper end of the storage tank 1 for material handling.
[0050] As one specific embodiment of the stem cell storage test tube insulation device provided in the application, please refer to Figure 3 The bottom of the placement box 4 has positioning grooves 41 on both sides, and positioning plugs 42 are provided at the corresponding positions of the placement slot 201 and the picking claw 34.
[0051] It should be understood that by setting the positioning slot 41 and the positioning plug 42, stability is maintained when placing and removing the box 4, reducing the risk of falling.
[0052] In some feasible embodiments, the positioning plug 42 is a cylindrical shape with a chamfered top.
[0053] Although the present invention has been described in detail with reference to the foregoing embodiments, those skilled in the art can still modify the technical solutions described in the foregoing embodiments or make equivalent substitutions for some of the technical features. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present invention should be included within the protection scope of the present invention.
Claims
1. A stem cell storage test tube insulation device, characterized in that, include: A storage tank connected to a liquid nitrogen cooling system, and a removable external material handling cover is provided at the top of the storage tank; A storage rack is rotatably installed inside the storage tank. The storage tank is fixedly connected to a first motor, the output end of which is connected to the storage rack. The storage rack has multiple layers, and each layer has multiple placement slots arranged in a circumferential array. A pick-and-place rack is fixedly installed on the upper end of the storage tank; A material picking tube is slidably mounted on the picking and placing frame. The lower end of the material picking tube passes through the upper end of the storage tank. The picking and placing frame is fixedly connected to a first linear drive, and the output end of the first linear drive is fixedly connected to the material picking tube. The material receiving rail assembly is fixedly installed at the lower end of the material receiving tube. The material receiving rail assembly is a ball screw mechanism. A second motor is provided at the upper end of the material receiving tube, and the output end of the second motor is connected to the material receiving rail assembly. The material handling claw is fixedly installed at the output end of the material handling rail assembly. The stem cell storage tube is placed in the placement box, and the placement box is placed in the placement slot.
2. The stem cell storage test tube insulation device according to claim 1, characterized in that: The storage rack includes an external rack and an internal rack, both of which are rotatably mounted on the storage tank. The material picking tube is located between the external rack and the internal rack. A third motor is fixedly mounted on the first linear drive output end, and the material picking tube is mounted on the output end of the third motor.
3. The stem cell storage test tube insulation device according to claim 2, characterized in that: The built-in frame and the external frame are not coaxial, and the side of the built-in frame away from the material picking rail assembly is closer to the external frame.
4. The stem cell storage test tube insulation device according to claim 1, characterized in that: The upper end of the storage rack is provided with a positioning through hole corresponding to the position of the bayonet. The storage tank is slidably mounted with a conical positioning rod, and the conical positioning rod is connected to a second linear drive.
5. The stem cell storage test tube insulation device according to claim 1, characterized in that: An inner material handling cover is fixedly installed at the lower end of the material handling claw, and the inner material handling cover seals the storage tank from the inside of the upper end of the storage tank.
6. The stem cell storage test tube insulation device according to claim 1, characterized in that: The bottom of the placement box is provided with positioning grooves on both sides, and the placement slot and the corresponding position of the picking claw are provided with positioning plugs.
7. The stem cell storage test tube insulation device according to claim 2, characterized in that: A positioning ring is fixedly installed at the first linear drive output end, and the material picker tube is rotatably installed inside the positioning ring. A limiting protrusion is fixedly provided on the inner side of the positioning ring, and a limiting arc groove is opened on the outer side of the material picker tube.