Novel gas chromatograph-mass spectrometer sampling device

Abstract

The utility model discloses a novel gas chromatograph-mass spectrometer sample introduction device, which relates to the technical field of sample introduction devices, and comprises an openable sample introduction box body, the sample introduction box body is provided with a sample introduction pipe and a sample discharge pipe which are arranged along the diagonal direction of the sample introduction box body, two partition plates which are parallel to each other and are used for separating space are arranged in the sample introduction box body, and the two partition plates are arranged in the sample introduction box body. A filter screen is detachably mounted on each partition plate, and a rotary cleaning mechanism which is in contact with the filter screen and is used for cleaning the filter screen is mounted on each partition plate; a temperature control mechanism is arranged on the front side of the sample injection box body. Revolution and rotation of the net cleaning brush roller are achieved through the rotary cleaning mechanism, the filter net is prevented from being blocked, the flow speed is guaranteed to be stable, refrigeration and heating are accurately controlled through the temperature controller, volatilization and degradation of flavor substances are reduced, the accuracy of experimental data is improved, in addition, the rotary cleaning mechanism can stir samples, promote convective heat exchange and improve heat exchange efficiency during cleaning, and the working efficiency is improved. And the sample can quickly reach the required temperature.

Description

Technical Field

[0001] This utility model relates to the field of sample introduction device technology, and in particular to a novel sample introduction device for a gas chromatography-mass spectrometry (GC-MS) instrument. Background Technology

[0002] Gas chromatography-mass spectrometry (GC-MS) instruments combine gas chromatography and mass spectrometry. This effective combination will provide chemists and biochemists with a highly efficient tool for qualitative and quantitative analysis of complex organic compounds. GC-MS instruments require connection to an injection device during use.

[0003] The document with publication number CN212228858U discloses a sample introduction device for a gas chromatography-mass spectrometry (GC-MS) instrument, including an openable sample introduction shell. The sample introduction shell is provided with a sealed filter chamber. The sample introduction shell is provided with an inlet tube and an outlet tube, both of which are connected to the filter chamber. The filter chamber is provided with at least two parallel partitions that are used to separate the space. The partition part is a filter screen, and the rest is a solid surface, which realizes a comprehensive and efficient filtration effect.

[0004] However, in the aforementioned existing technologies, the filter screen cannot be cleaned in time during the sample filtration process, which can easily cause blockage after long-term use. The accumulation of impurities leads to an increase in the pressure difference across the filter screen, affecting the filtration effect. At the same time, given that the sample is a fresh substance, volatile flavor substances are easily lost or degraded due to temperature. Existing technologies cannot meet the requirements for sample temperature control, especially for fresh substances, and cannot suppress the loss and chemical changes of volatile components, directly affecting the accuracy of the sample analysis results. Utility Model Content

[0005] The purpose of this invention is to solve the problems existing in the prior art by proposing a novel gas chromatography-mass spectrometry (GC-MS) sample introduction device.

[0006] To achieve the above objectives, the present invention adopts the following technical solution:

[0007] A novel gas chromatography-mass spectrometry (GC-MS) sample introduction device includes an openable sample introduction chamber. The sample introduction chamber is provided with an inlet tube and an outlet tube arranged along the diagonal direction of the sample introduction chamber. The sample introduction chamber is provided with two parallel partitions for separating the space. A filter screen can be detachably installed on each partition. A rotary cleaning mechanism is installed on the partition to contact the filter screen and clean the filter screen.

[0008] A temperature control mechanism is provided on the front side of the sample injection chamber. The temperature control mechanism includes a liquid storage tank, a temperature controller, a semiconductor cooling plate, a heating rod, a circulation pump, a circulation pipe, and a temperature sensor. The circulation pipe is led out from the liquid storage tank, passes through the sample injection chamber and the partition, and enters the liquid storage tank.

[0009] Preferably, adjacent filter screens are staggered, and the pore size of the filter screens gradually decreases along the flow direction of the sample in the injection chamber.

[0010] Preferably, the rotating cleaning mechanism includes a bracket, a motor, a mounting plate, and a cleaning brush roller. The bracket is fixedly mounted on the partition plate, the motor is mounted on the bracket, the mounting plate is fixedly connected to the output end of the motor, and the cleaning brush roller is rotatably mounted on the bracket and contacts the filter.

[0011] Preferably, a bevel gear disc is fixedly connected to one side of the bracket, a support is fixedly connected to the bracket, a rotating shaft is rotatably mounted on the support, a bevel gear that meshes with the bevel gear disc is fixedly connected to one end of the rotating shaft, a main rotating disk is fixedly connected to the other end of the rotating shaft, a secondary rotating disk is fixedly connected to one end of the cleaning brush roller, and a transmission belt is provided between the main rotating disk and the secondary rotating disk for transmission.

[0012] Preferably, the liquid storage tank is fixedly connected to the front of the sample injection chamber. The semiconductor cooling plate, heating rod, and circulation pump are all installed inside the liquid storage tank and electrically connected to the temperature controller. The temperature sensors are evenly installed inside the sample injection chamber and electrically connected to the temperature controller. The cold end of the semiconductor cooling plate is located inside the liquid storage tank, and the hot end of the semiconductor cooling plate is located outside the liquid storage tank. One end of the circulation pipe is connected to the circulation pump.

[0013] Preferably, the temperature control range of the temperature controller is 0-4℃, and the liquid storage tank is filled with ethylene glycol aqueous solution, the liquid level of which needs to be higher than that of the semiconductor cooling plate, heating rod and circulation pump.

[0014] Preferably, the partition plate has a through groove with a stepped cross-section. An installation frame is provided in the through groove, and the filter screen is fixedly connected in the installation frame. The installation frame is installed on the partition plate by bolts, and a sealing lip is fixedly connected to the installation frame to achieve a seal between the installation frame and the partition plate.

[0015] Preferably, the sealing lip includes an integrally formed first lip, a second lip, and a third lip. The first lip is fixedly connected to the mounting frame. When the mounting frame is connected to the partition, the second lip and the first lip fit together, and the first lip, the second lip, and the third lip seal the through groove.

[0016] The motor is selected to be a high- and low-temperature motor that can operate in liquids. The cleaning brush roller uses soft nylon / carbon fiber bristles (Shore A hardness 70-90) to evenly scrape the surface of the filter screen and avoid excessive wear in some areas. The other settings can be similar to existing technologies. Strong magnetic plates and impurity adsorption rods can be selected. Meanwhile, the temperature controller, temperature sensor, semiconductor cooling plate, heating rod and circulation pump are all products disclosed in existing technologies. Since their specific models are all existing technologies, they will not be described in detail here.

[0017] Compared with the prior art, the advantages and positive effects of this utility model are as follows:

[0018] 1. In this application, the sample passes sequentially through staggered filter screens with decreasing pore size on two-stage partitions, forming an "S-shaped" path to extend the contact time and intercept impurities step by step, ensuring thorough filtration. At the same time, during filtration, the cleaning brush roller in the rotating cleaning mechanism, which can rotate and revolve, thoroughly removes the residues attached to the filter screen, preventing clogging. Dynamic cleaning can avoid the increase in pressure difference on both sides of the filter screen caused by impurity accumulation, ensuring a stable sample flow rate and completing the cleaning without interrupting the process.

[0019] 2. In this application, the opening and closing of the semiconductor cooling plate and heating rod under different conditions is controlled by a temperature controller. Through cooling heat exchange or heating heat exchange, the sample is kept within the required temperature range to minimize the volatilization and degradation of flavor substances. This provides reliable technical support for the analysis of fresh substances and ensures the accuracy and scientific nature of experimental data.

[0020] 3. In this application, heat exchange and filtration can be carried out simultaneously. The rotating cleaning mechanism can also stir the sample while cleaning, breaking the internal temperature gradient of the sample and making the heat distribution more uniform. By promoting convection heat transfer and increasing the contact area, stirring can accelerate the heat transfer and dissipation / absorption process, thereby improving the heat exchange efficiency and enabling the sample to quickly reach the required temperature range. Attached Figure Description

[0021] Figure 1 This utility model presents a three-dimensional structural schematic diagram of a novel gas chromatography-mass spectrometry (GC-MS) sample introduction device;

[0022] Figure 2 A bottom view of the novel gas chromatography-mass spectrometry (GC-MS) sample introduction device is provided for this utility model.

[0023] Figure 3 This utility model presents a partial cross-sectional structural diagram of a novel gas chromatography-mass spectrometry (GC-MS) sample introduction device;

[0024] Figure 4 A schematic diagram of the rotating cleaning mechanism of the novel gas chromatography-mass spectrometry (GC-MS) sample introduction device is provided for this utility model.

[0025] Figure 5 This utility model provides a schematic diagram of the cross-sectional structure of the partition plate of a novel gas chromatography-mass spectrometry (GC-MS) sample introduction device;

[0026] Figure 6 This utility model proposes a novel gas chromatography-mass spectrometry (GC-MS) sample introduction device. Figure 5 Enlarged diagram of point A in the middle.

[0027] Legend: 100, Sample inlet box; 101, Sample inlet tube; 102, Sample outlet tube; 200, Partition plate; 201, Through groove; 300, Filter screen; 400, Rotary cleaning mechanism; 401, Support; 402, Motor; 403, Mounting plate; 404, Cleaning brush roller; 405, Bevel gear disc; 406, Support; 407, Rotating shaft; 408, Bevel gear; 409, Main turntable; 410, Auxiliary turntable; 411, Drive belt; 500, Temperature control mechanism; 501, Liquid storage tank; 502, Temperature controller; 503, Semiconductor cooling plate; 504, Heating rod; 505, Circulation pump; 506, Circulation pipe; 507, Temperature sensor; 600, Mounting frame; 700, Sealing lip; 701, First lip; 702, Second lip; 703, Third lip. Detailed Implementation

[0028] To better understand the above-mentioned objectives, features, and advantages of this utility model, the present utility model will be further described below with reference to the accompanying drawings and embodiments. It should be noted that, unless otherwise specified, the embodiments and features described in these embodiments can be combined with each other.

[0029] Many specific details are set forth in the following description in order to provide a full understanding of the present invention. However, the present invention may also be implemented in other ways different from those described herein. Therefore, the present invention is not limited to the specific embodiments disclosed in the following specification.

[0030] like Figure 1-6 As shown, this utility model provides a novel gas chromatography-mass spectrometry (GC-MS) sample introduction device, including an openable sample introduction chamber 100. The sample introduction chamber 100 is provided with an inlet tube 101 and an outlet tube 102 arranged along the diagonal direction of the sample introduction chamber 100. The sample introduction chamber 100 is provided with two parallel partitions 200 for separating the space. Each partition 200 is detachably equipped with a filter screen 300. A rotary cleaning mechanism 400 is installed on the partition 200 to contact the filter screen 300 and clean the filter screen 300.

[0031] A temperature control mechanism 500 is provided on the front side of the sample injection chamber 100. The temperature control mechanism 500 includes a liquid storage tank 501, a temperature controller 502, a semiconductor cooling plate 503, a heating rod 504, a circulation pump 505, a circulation pipe 506, and a temperature sensor 507. The circulation pipe 506 is led out from the liquid storage tank 501 and passes through the sample injection chamber 100 and the partition 200 before entering the liquid storage tank 501.

[0032] In this embodiment, adjacent filter screens 300 are staggered, and the pore size of the filter screens 300 gradually decreases along the flow direction of the sample in the sample inlet box 100. The partition 200, together with the staggered filter screens 300, can extend the sample flow path, and the filter screens 300 with different pore sizes can achieve step-by-step filtration, so that the sample can be fully filtered.

[0033] In this embodiment, the rotating cleaning mechanism 400 includes a bracket 401, a motor 402, a mounting plate 403, and a cleaning brush roller 404. The bracket 401 is fixedly mounted on the partition plate 200, the motor 402 is mounted on the bracket 401, the mounting plate 403 is fixedly connected to the output end of the motor 402, and the cleaning brush roller 404 is rotatably mounted on the bracket 401 and contacts the filter. The bracket 401 supports the motor 402. When the motor 402 operates, it drives the mounting plate 403 to rotate, thereby driving the cleaning brush roller 404 to sweep across the filter screen 300 for cleaning.

[0034] In this embodiment, a bevel gear disk 405 is fixedly connected to one side of the bracket 401, a support 406 is fixedly connected to the bracket 401, and a rotating shaft 407 is rotatably mounted on the support 406. One end of the rotating shaft 407 is fixedly connected to a bevel gear 408 that meshes with the bevel gear disk 405, and the other end of the rotating shaft 407 is fixedly connected to a main rotating disk 409. One end of the cleaning brush roller 404 is fixedly connected to a secondary rotating disk 410, and a transmission belt is provided between the main rotating disk 409 and the secondary rotating disk 410 for transmission. 411. When the mounting plate 403 rotates, the support 406 causes the rotating shaft 407 to drive the bevel gear 408 to move along the circumference of the bevel gear disk 405. During this process, the bevel gear 408 rotates under the action of the bevel gear disk 405, and then the rotating shaft 407 causes the main rotating disk 409 to rotate. The main rotating disk 409 drives the auxiliary rotating disk 410 to rotate the cleaning brush roller 404 through the transmission belt 411, so that the cleaning brush roller 404 can rotate synchronously to clean the filter screen 300.

[0035] In this embodiment, the storage tank 501 is fixedly connected to the front of the sample injection chamber 100. The semiconductor cooling plate 503, the heating rod 504, and the circulation pump 505 are all installed inside the storage tank 501 and electrically connected to the temperature controller 502. The temperature sensors 507 are evenly installed inside the sample injection chamber 100 and electrically connected to the temperature controller 502. The cold end of the semiconductor cooling plate 503 is located inside the storage tank 501, and the hot end of the semiconductor cooling plate 503 is located outside the storage tank 501. One end of the circulation pipe 506 is connected to the circulation pump 505. The semiconductor cooling plate 503 and the heating rod 504 can be cooled and heated respectively. The heat is pumped out by the circulation pump 505, flows out through the circulation pipe 506, and finally returns to the storage tank 501, realizing circulating heat exchange.

[0036] In this embodiment, the temperature control range of the thermostat 502 is 0-4℃. The liquid storage tank 501 is filled with ethylene glycol aqueous solution. The liquid level of the ethylene glycol aqueous solution needs to be higher than the semiconductor cooling plate 503, the heating rod 504 and the circulation pump 505. By adjusting the concentration of the ethylene glycol aqueous solution, its freezing point is made much lower than 0℃ to avoid freezing during refrigeration. The boiling point of 50% ethylene glycol solution is about 107℃, and it is not easy to vaporize when heated, making it suitable for rapid heat exchange.

[0037] In this embodiment, a through groove 201 is provided on the partition 200. The cross-section of the through groove 201 is stepped. An installation frame 600 is provided in the through groove 201. The filter screen 300 is fixedly connected in the installation frame 600. The installation frame 600 is installed on the partition 200 by bolts. A sealing lip 700 is fixedly connected to the installation frame 600 to achieve a seal between the installation frame 600 and the partition 200. The installation of the mounting frame 600 and the matching filter screen 300 by bolts allows them to be disassembled for maintenance or replacement. At the same time, the installation is relatively firm and will not loosen when the sample passes through and the cleaning brush roller 404 is used for cleaning.

[0038] In this embodiment, the sealing lip 700 includes an integrally formed first lip 701, a second lip 702, and a third lip 703. The first lip 701 is fixedly connected to the mounting frame 600. When the mounting frame 600 is connected to the partition 200, the second lip 702 and the first lip 701 fit together, and the first lip 701, the second lip 702, and the third lip 703 seal the through groove 201. When the mounting frame 600 enters the through groove 201, the second lip 702 is pressed against the inner wall of the through groove 201. The first lip 701, the second lip 702, and the third lip 703 are completely fitted together to seal, ensuring that the sample can only pass through the filter screen 300 and the partition 200, thus ensuring that the sample is filtered.

[0039] How to use and how to work this device:

[0040] After the sample enters the sample box 100 through the sample inlet tube 101, it passes through the staggered filter screens 300 on the two-stage partitions 200 with pore sizes ranging from large to small, forming an "S-shaped" path to extend the contact time and intercept impurities step by step, ensuring thorough filtration. During filtration, the motor 402 drives the mounting plate 403 to rotate, which in turn drives the cleaning brush roller 404 to sweep along the surface of the filter screen 300 for cleaning. At the same time, the bevel gear 408 moves along the circumference of the bevel gear disk 405. The bevel gear 408 rotates under the action of the bevel gear disk 405 and drives the rotating shaft 407 to rotate. Through the main turntable 409, the transmission belt 411 and the auxiliary turntable 410, the cleaning brush roller 404 rotates, realizing the simultaneous dual motion of the cleaning brush roller 404's revolution and rotation. This thoroughly removes the residues attached to the filter screen, prevents clogging, and the dynamic cleaning avoids the increase in pressure difference on both sides of the filter screen 300 caused by the accumulation of impurities, ensuring a stable sample flow rate. The cleaning can be completed without interrupting the process.

[0041] Temperature sensor 507 monitors the sample temperature, and temperature controller 502 collects data from temperature sensor 507 in real time. When the sample temperature is greater than 4°C, temperature controller 502 controls the operation of semiconductor cooling plate 503 and circulation pump 505, and heating rod 504 is turned off. Semiconductor cooling plate 503 cools the ethylene glycol aqueous solution, which is then pumped out by circulation pump 505, flows through circulation pipe 506, and returns to storage tank 501. When the ethylene glycol aqueous solution flows in circulation pipe 506, it exchanges heat with the sample in injection chamber 100 to achieve cooling. When the sample temperature is less than 0°C, temperature controller 502 controls the operation of heating rod 504 and circulation pump 505, and semiconductor cooling plate 503 is turned off. Heating rod 504 heats the ethylene glycol aqueous solution, which is then pumped out by circulation pump 505, flows through circulation pipe 506, and returns to storage tank 501. When the ethylene glycol aqueous solution flows in circulation pipe 506, it exchanges heat with the sample in injection chamber 100 to achieve heating.

[0042] During the above process, the motor 402 drives the mounting plate 403, the cleaning brush roller 404, the support 406, the rotating shaft 407, and the bevel gear 408 to move, which can stir the sample to break the internal temperature gradient and make the heat distribution more uniform. By promoting convection heat transfer and increasing the contact area, stirring can accelerate the heat transfer and dissipation / absorption process, thereby improving the heat exchange efficiency and enabling the sample to quickly reach the required temperature range. This minimizes the volatilization and degradation of flavor substances, provides reliable technical support for the analysis of fresh substances, and ensures the accuracy and scientific nature of experimental data.

[0043] The above description is merely a preferred embodiment of the present utility model and is not intended to limit the present utility model in any other way. Any person skilled in the art may make changes or modifications to the above-disclosed technical content to create equivalent embodiments for application in other fields. However, any simple modifications, equivalent changes, and modifications made to the above embodiments based on the technical essence of the present utility model without departing from the technical solution of the present utility model shall still fall within the protection scope of the technical solution of the present utility model.

Claims

1. A novel gas chromatography-mass spectrometry (GC-MS) sample introduction device, characterized in that: The sample injection chamber (100) is openable and has an inlet tube (101) and an outlet tube (102). The inlet tube (101) and the outlet tube (102) are arranged diagonally along the sample injection chamber (100). The sample injection chamber (100) has two parallel partitions (200) for separating the space. Each partition (200) is detachably equipped with a filter screen (300). A rotary cleaning mechanism (400) is installed on the partition (200) to contact the filter screen (300) and clean the filter screen (300). A temperature control mechanism (500) is provided on the front side of the sample injection chamber (100). The temperature control mechanism (500) includes a liquid storage tank (501), a temperature controller (502), a semiconductor cooling plate (503), a heating rod (504), a circulation pump (505), a circulation pipe (506), and a temperature sensor (507). The circulation pipe (506) is led out from the liquid storage tank (501) and passes through the sample injection chamber (100) and the partition (200) before entering the liquid storage tank (501). The thermostat (502) receives the temperature signal from the temperature sensor (507) and sends a control signal to control the opening or closing of the semiconductor cooling plate (503), the heating rod (504) and the circulation pump (505).

2. The novel gas chromatography-mass spectrometry (GC-MS) sample introduction device according to claim 1, characterized in that: The filter screens (300) on the adjacent partitions (200) are staggered, and the aperture of the filter screens (300) gradually decreases along the flow direction of the sample in the sample inlet box (100).

3. The novel gas chromatography-mass spectrometry (GC-MS) sample introduction device according to claim 1, characterized in that: The rotating cleaning mechanism (400) includes a bracket (401), a motor (402), a mounting plate (403), and a cleaning brush roller (404). The bracket (401) is fixedly mounted on the partition plate (200), the motor (402) is mounted on the bracket (401), the mounting plate (403) is fixedly connected to the output end of the motor (402), and the cleaning brush roller (404) is rotatably mounted on the bracket (401) and contacts the filter.

4. The novel gas chromatography-mass spectrometry (GC-MS) sample introduction device according to claim 3, characterized in that: A bevel gear disc (405) is fixedly connected to one side of the bracket (401), a support (406) is fixedly connected to the bracket (401), a rotating shaft (407) is rotatably mounted on the support (406), a bevel gear (408) that meshes with the bevel gear disc (405) is fixedly connected to one end of the rotating shaft (407), a main turntable (409) is fixedly connected to the other end of the rotating shaft (407), a secondary turntable (410) is fixedly connected to one end of the cleaning brush roller (404), and a transmission belt (411) is provided between the main turntable (409) and the secondary turntable (410).

5. The novel gas chromatography-mass spectrometry (GC-MS) sample introduction device according to claim 1, characterized in that: The liquid storage tank (501) is fixedly connected to the front of the sample injection chamber (100). The semiconductor cooling plate (503), heating rod (504) and circulation pump (505) are all installed inside the liquid storage tank (501) and electrically connected to the temperature controller (502). The temperature sensor (507) is evenly installed inside the sample injection chamber (100) and electrically connected to the temperature controller (502). The cold end of the semiconductor cooling plate (503) is located inside the liquid storage tank (501), and the hot end of the semiconductor cooling plate (503) is located outside the liquid storage tank (501). One end of the circulation pipe (506) is connected to the circulation pump (505).

6. The novel gas chromatography-mass spectrometry (GC-MS) sample introduction device according to claim 1, characterized in that: The storage tank (501) is filled with an aqueous ethylene glycol solution, and the level of the aqueous ethylene glycol solution needs to be higher than that of the semiconductor cooling plate (503), the heating rod (504) and the circulation pump (505).

7. The novel gas chromatography-mass spectrometry (GC-MS) sample introduction device according to claim 1, characterized in that: The partition (200) has a through groove (201) with a stepped cross-section. A mounting frame (600) is provided in the through groove (201). The filter screen (300) is fixedly connected in the mounting frame (600). The mounting frame (600) is installed on the partition (200) by bolts. A sealing lip (700) is fixedly connected to the mounting frame (600) to achieve a seal between the mounting frame (600) and the partition (200).

8. The novel gas chromatography-mass spectrometry (GC-MS) sample introduction device according to claim 7, characterized in that: The sealing lip (700) includes an integrally formed first lip (701), a second lip (702), and a third lip (703). The first lip (701) is fixedly connected to the mounting frame (600). When the mounting frame (600) is connected to the partition (200), the second lip (702) and the first lip (701) fit together, and the first lip (701), the second lip (702), and the third lip (703) seal the through groove (201).

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