Anti-caking raw material medicine vacuum subpackaging mechanism

Abstract

The utility model relates to the technical field of bulk drug processing, and discloses an anti-caking bulk drug vacuum subpackaging mechanism which comprises a storage tank and a weighing box, the top of the storage tank penetrates through and is connected with an end cover in a sliding mode, the top of the end cover is fixedly connected with a first motor, and the output end of the first motor is fixedly connected with a rotating rod. The outer ring of the rotating rod penetrates through and is fixedly connected with uniformly distributed shells, the inner wall of each shell is rotatably connected with a bevel gear set, the two sides of each bevel gear set are fixedly connected with turning plates, the outer ring of the rotating rod is fixedly connected with uniformly distributed connecting rods, and one end of each connecting rod is fixedly connected with a scraping plate. According to the utility model, through the cooperation of the end cover, the first motor, the rotating rod, the shell, the bevel gear set, the turning plate, the connecting rod, the scraping plate, the fixed block and the bolt, the material caking trend is broken through mechanical stirring, the bulk drug is prevented from caking due to standing and compaction, the viscosity of the bulk drug is reduced, and the bulk drug caking device is suitable for bulk drugs which are sensitive to temperature but easy to cake.

Description

Technical Field

[0001] This utility model relates to the field of active pharmaceutical ingredient (API) processing technology, specifically to an anti-caking API vacuum dispensing mechanism. Background Technology

[0002] Active pharmaceutical ingredients (APIs) often contain granules, a common physical form of APIs. Granular APIs refer to solid granular substances formed through processes such as crystallization and granulation. Their particle size is typically in the range of micrometers to millimeters, exhibiting a clear particle size distribution and good flowability. These APIs retain the chemical activity of the active ingredient while improving the problems of agglomeration and poor flowability associated with powdered APIs through granulation. For example, in tablet preparation, granular APIs can be directly used for compression, reducing dust and ensuring uniform tablet weight. When used for capsule filling, the granular form allows for precise control of the fill weight, avoiding dosage deviations caused by powder accumulation. The granular structure can be optimized by adjusting the preparation process (such as spray drying and wet granulation) to achieve parameters such as bulk density and surface roughness, adapting to different formulation requirements (such as immediate-release and sustained-release). Simultaneously, the granular form reduces hygroscopicity and improves storage stability, making it an important raw material form for improving process feasibility and drug quality in oral solid dosage form production.

[0003] In existing technologies, the method to prevent the active pharmaceutical ingredient (API) from caking is to add anti-caking agents. This involves mixing a small amount of inert material with adsorption or barrier properties (such as silica or magnesium stearate) into the API particles. The powdered structure of these materials adsorbs moisture from the particle surface or forms a physical barrier between particles, preventing them from sticking together due to moisture absorption, electrostatic effects, or mechanical compression. For example, silica, a commonly used anti-caking agent, has a porous structure that adsorbs moisture from the air, reducing the wettability of the API particle surface; magnesium stearate, on the other hand, reduces friction and adhesion between particles by forming a lubricating film on the particle surface.

[0004] If the anti-caking agent is not pure enough or contains trace impurities, it may introduce new contaminants and affect the quality standards of the active pharmaceutical ingredient (API). After adding the anti-caking agent, it is necessary to additionally test the residual amount of excipients and the uniformity of mixing in the API, which increases the cost and time of quality control and makes it impossible to achieve an efficient anti-caking method. To address the above problems, an anti-caking API vacuum dispensing mechanism is proposed. Utility Model Content

[0005] The purpose of this invention is to provide an anti-caking vacuum dispensing mechanism for pharmaceutical raw materials, which solves the problem that the prior art cannot achieve an efficient anti-caking method.

[0006] To achieve the above objectives, this utility model provides the following technical solution: a vacuum dispensing mechanism for anti-caking raw materials, comprising a storage tank and a weighing box. An end cap is slidably connected through the top of the storage tank. A first motor is fixedly connected to the top of the end cap. A rotating rod is fixedly connected to the output end of the first motor. A uniformly distributed outer shell is slidably connected through the outer ring of the rotating rod. A bevel gear set is rotatably connected to the inner wall of the outer shell. Flip plates are fixedly connected to both sides of the bevel gear set. A uniformly distributed connecting rod is fixedly connected to the outer ring of the rotating rod. A scraper is fixedly connected to one end of the connecting rod. A fixing block is fixedly connected to the outer ring of the end cap. A bolt is slidably connected through the top of the fixing block. Heating filaments are fixedly connected to both sides of the inner wall of the storage tank. A limit component is rotatably connected to the top of the inner wall of the storage tank, and the outer ring of the limit component is slidably connected through the outer shell. A first support column is fixedly connected to the bottom of the storage tank. A cleaning component is provided at the rear end of the weighing box.

[0007] By adopting the above technical solution, the end cap can be easily disassembled with bolts, the connection between the end cap and the storage tank is in a sealed state, the heating filament can heat the raw materials in the storage tank, and the first support can support the storage tank.

[0008] As a further description of the above technical solution: the cleaning component includes a second motor, which is fixedly connected to the rear end of the weighing box. A lead screw is fixedly connected to the output end of the second motor, and a sliding plate is threadedly connected to the outer ring of the lead screw. A fixing plate is fixedly connected to the bottom of the sliding plate.

[0009] By adopting the above technical solution, the second motor drives the lead screw to rotate, and the rotation of the lead screw causes the slide to move.

[0010] As a further description of the above technical solution: a scraper is fixedly connected to the rear end of the fixed plate, and baffles are fixedly connected to the top of the inner wall of the weighing box.

[0011] By adopting the above technical solution, the baffle can guide the falling raw materials.

[0012] As a further description of the above technical solution: a bracket is fixedly connected to the top of the weighing box, a hydraulic cylinder is fixedly connected to the top of the bracket, and a sealing plate is fixedly connected to the output end of the hydraulic cylinder.

[0013] By adopting the above technical solution, the hydraulic cylinder drives the sealing plate to move up and down.

[0014] As a further description of the above technical solution: a discharge port is fixedly connected to the rear end of the weighing box, a pressure sensor is fixedly connected to the bottom of the inner wall of the weighing box, and a second support column is fixedly connected to the bottom of both the weighing box and the discharge port.

[0015] By adopting the above technical solution, the pressure sensor can detect the weight of the raw material, and the feeding port can process the raw material.

[0016] As a further description of the above technical solution: a vacuum pump is fixedly connected to one side of the weighing box, and the output end of the vacuum pump passes through and is fixedly connected to the weighing box.

[0017] By adopting the above technical solution, a filter screen is installed at the output end of the vacuum pump, which can prevent raw materials from entering the vacuum pump and avoid damage to the raw material pump.

[0018] As a further description of the above technical solution: a control panel is fixedly connected to the rear end of the storage tank.

[0019] By adopting the above technical solution, the motor inside the device can be easily controlled through the control panel.

[0020] As a further description of the above technical solution: a pipe is connected through and fixedly connected to the bottom rear end of the storage tank, and one end of the pipe is connected through and fixedly connected to the weighing box.

[0021] By adopting the above technical solution, the material inside the storage tank can be transferred to the weighing box through a pipeline. The pipeline is made of special material, which can prevent the accumulation of raw materials.

[0022] Compared with the prior art, the beneficial effects of this utility model are as follows:

[0023] 1. This utility model provides an anti-caking vacuum dispensing mechanism for pharmaceutical raw materials. Firstly, through the cooperation of the end cap, first motor, rotating rod, outer shell, bevel gear set, flip plate, connecting rod, scraper, fixing block, and bolts, the material's tendency to clump is broken by mechanical agitation, preventing the pharmaceutical raw materials from clumping due to static compaction and reducing the viscosity of the raw materials. Combined with the mechanical movement of the flip plate and scraper, it is suitable for temperature-sensitive but easily clumping pharmaceutical raw materials, avoiding problems such as uneven particle size and uneven distribution of active ingredients caused by clumping, and ensuring the purity and efficacy stability of the pharmaceutical raw materials.

[0024] 2. The present invention provides an anti-caking type vacuum dispensing mechanism for raw pharmaceutical materials. Through the cooperation of a second motor, lead screw, sliding plate, fixed plate, scraper, baffle, support, hydraulic cylinder, sealing plate, and bolts, it ensures that residual materials in the weighing box are thoroughly cleaned, avoids cross-contamination between different batches of raw materials, reduces raw material waste, and achieves zero material waste. It is especially suitable for expensive raw pharmaceutical materials, reduces production costs, and the negative pressure transmission prevents the entry of external air and impurities, ensuring the purity of the raw materials and preventing contamination from affecting the efficacy. Attached Figure Description

[0025] Figure 1 This is a perspective view of the present utility model;

[0026] Figure 2 This is a sectional perspective view of the storage tank of this utility model;

[0027] Figure 3 This is a sectional perspective view of the weighing box of this utility model;

[0028] Figure 4 This is a schematic diagram of the lead screw of this utility model.

[0029] Legend:

[0030] 1. Storage tank; 2. End cap; 3. First motor; 4. Rotating rod; 5. Housing; 6. Bevel gear set; 7. Flip plate; 8. Connecting rod; 9. Scraper; 10. Fixing block; 11. Bolt; 12. Heating filament; 13. First support column; 14. Weighing box; 15. Second motor; 16. Lead screw; 17. Slide plate; 18. Fixing plate; 19. Scraper frame; 20. Baffle; 21. Bracket; 22. Hydraulic cylinder; 23. Sealing plate; 24. Discharge port; 25. Pressure sensor; 26. Second support column; 27. Vacuum pump; 28. Control panel; 29. ​​Pipeline; 30. Limiting assembly. Detailed Implementation

[0031] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0032] To further understand the contents of this utility model, a detailed description of this utility model will be provided with reference to the accompanying drawings.

[0033] Reference Figure 1 and Figure 3 and Figure 4This utility model discloses an anti-caking type vacuum dispensing mechanism for raw materials, comprising a storage tank 1 and a weighing box 14. A discharge port 24 is fixedly connected to the rear end of the weighing box 14. A pressure sensor 25 is fixedly connected to the bottom of the inner wall of the weighing box 14. The pressure sensor 25 transmits the detected weight to a control panel 28 for easy monitoring of the control panel 28. A second support column 26 is fixedly connected to the bottom of both the weighing box 14 and the discharge port 24, providing support for the weighing box 14 and the discharge port 24. A vacuum pump 27 is fixedly connected to one side of the weighing box 14, and the output end of the vacuum pump 27 penetrates and is fixedly connected to the weighing box 14. The vacuum pump 27 can create a negative pressure state inside the weighing box 14. A control panel 28 is fixedly connected to the rear end of the storage tank 1, allowing easy viewing of the parameters within the device. A pipe 29 is fixedly connected to the bottom of the rear end of the storage tank 1, and one end of the pipe 29 penetrates and is fixedly connected to the weighing box 14.

[0034] Reference Figure 2 The storage tank 1 has an end cover 2 that slides through and is connected to the top. A first motor 3 is fixedly connected to the top of the end cover 2. A rotating rod 4 is fixedly connected to the output end of the first motor 3. The first motor 3 drives the rotating rod 4 to rotate. A uniformly distributed outer shell 5 is connected through and fixedly connected to the outer ring of the rotating rod 4. The rotation of the rotating rod 4 causes the outer shell 5 to rotate synchronously. A bevel gear set 6 is rotatably connected to the inner wall of the outer shell 5. The bevel gear set 6 contains three bevel gears. Two opposing bevel gears rotate in opposite directions. Flip plates 7 are fixedly connected to both sides of the bevel gear set 6. The driven bevel gear drives the flip plates 7 to rotate. A uniformly distributed connecting rod 8 is fixedly connected to the outer ring of the rotating rod 4. A scraper is fixedly connected to one end of the connecting rod 8. The rotation of the plate 9 and scraper 9 can scrape the inner wall of the storage tank 1. The outer ring of the end cover 2 is fixedly connected to the fixing block 10. The top of the fixing block 10 is rotatably connected to the bolt 11. The end cover 2 can be disassembled by rotating the bolt 11, which facilitates the cleaning of the storage tank 1. Heating filaments 12 are fixedly connected to both sides of the inner wall of the storage tank 1. The top of the inner wall of the storage tank 1 is rotatably connected to the limit component 30. The limit component 30 limits the position of the outer shell 5, increases the support of the outer shell 5, and the outer ring of the limit component 30 is rotatably connected to the outer shell 5. The bottom of the storage tank 1 is fixedly connected to the first support column 13. The rear end of the weighing box 14 is provided with a cleaning component.

[0035] Reference Figure 3 and Figure 4The cleaning assembly includes a second motor 15, which is fixedly connected to the rear end of the weighing box 14. A lead screw 16 is fixedly connected to the output end of the second motor 15, driving the lead screw 16 to rotate. A sliding plate 17 is threaded onto the outer ring of the lead screw 16, and a nut pair is built into the sliding plate 17. The rotation of the lead screw 16 causes the sliding plate 17 to move. A fixed plate 18 is fixedly connected to the bottom of the sliding plate 17, and the movement of the sliding plate 17 causes the fixed plate 18 to move synchronously. The movement of the fixed plate 18 can push the raw material. A scraper 19 is fixedly connected to the rear end of the fixed plate 18, which can scrape the raw material in the weighing box 14. Baffles 20 are fixedly connected to the top of the inner wall of the weighing box 14, guiding the movement of the raw material. A bracket 21 is fixedly connected to the top of the weighing box 14, and a hydraulic cylinder 22 is fixedly connected to the top of the bracket 21. The bracket 21 fixes the position of the hydraulic cylinder 22, and a sealing plate 23 is fixedly connected to the output end of the hydraulic cylinder 22.

[0036] Working principle: The end cap 2 is connected to the fixing block 10 via bolts 11, enabling installation or removal from the storage tank 1 and facilitating internal maintenance. The first motor 3 is fixed to the end cap 2. After starting, it drives the rotating rod 4 to rotate. When the rotating rod 4 rotates, the outer shell 5 rotates synchronously. When the rotating rod 4 rotates, it drives the active bevel gear to rotate synchronously via a key connection. The active bevel gear meshes with the driven bevel gear. Utilizing the characteristic of vertically intersecting shaft transmission of bevel gears, the longitudinal rotation of the rotating rod 4 is converted into the lateral rotation of the driven bevel gear. The bevel gear set 6 inside the outer shell 5 drives the flap 7 to rotate, stirring the raw materials in the storage tank 1. At the same time, the connecting rod 8 on the rotating rod 4 drives the scraper 9 to rotate, scraping the inner wall of the storage tank 1. Combined with the heating filament 12, this multi-dimensional method prevents the raw materials from clumping. The limiting component 30 is fitted onto the outer shell 5. In addition, to ensure the rotational stability of the outer shell 5, the vacuum pump 27 extracts the air pressure inside the weighing box 14 to form a negative pressure state. The raw materials in the storage tank 1 can be transferred to the weighing box 14 through the pipe 29. The second motor 15 starts and drives the lead screw 16 to rotate, which drives the slide plate 17, the fixed plate 18 and the scraper 19 to move. The scraper 19 scrapes the inner wall of the weighing box 14 to clean the residual materials. The baffle 20 helps to regulate the falling path of the materials and prevent the raw materials from falling at the lead screw 16. The hydraulic cylinder 22 is fixed on the bracket 21 and drives the sealing plate 23 to rise and fall, controlling the opening and closing of the weighing box 14 and the discharge port 24. The pressure sensor 25 detects the raw materials. After reaching the quantitative level, the sealing plate 23 opens, and the material is discharged from the discharge port 24 through the cooperation between the fixed plate 18 and the scraper 19.

[0037] It should be noted that, in this document, relational terms such as "first" and "second" are used only to distinguish one entity or operation from another, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Furthermore, the terms "comprising," "including," or any other variations thereof are intended to cover non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements includes not only those elements but also other elements not expressly listed, or elements inherent to such process, method, article, or apparatus.

[0038] Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the present invention, the scope of which is defined by the appended claims and their equivalents.

Claims

1. A vacuum dispensing mechanism for anti-caking raw materials, comprising a storage tank (1) and a weighing box (14), characterized in that: The storage tank (1) has an end cover (2) that is slidably connected to the top. A first motor (3) is fixedly connected to the top of the end cover (2). A rotating rod (4) is fixedly connected to the output end of the first motor (3). A uniformly distributed outer shell (5) is slidably connected to the outer ring of the rotating rod (4). A bevel gear set (6) is rotatably connected to the inner wall of the outer shell (5). Flip plates (7) are fixedly connected to both sides of the bevel gear set (6). A uniformly distributed connecting rod (8) is fixedly connected to the outer ring of the rotating rod (4). One end of the connecting rod (8) is fixed. A scraper (9) is connected to the end cap (2). A fixing block (10) is fixedly connected to the outer ring of the end cap (2). A bolt (11) is connected through and rotatably to the top of the fixing block (10). A heating filament (12) is fixedly connected to both sides of the inner wall of the storage tank (1). A limit component (30) is rotatably connected to the top of the inner wall of the storage tank (1). The outer ring of the limit component (30) is connected through and fixedly to the outer shell (5). A first support column (13) is fixedly connected to the bottom of the storage tank (1). A cleaning component is provided at the rear end of the weighing box (14).

2. The anti-caking type raw material vacuum dispensing mechanism according to claim 1, characterized in that: The cleaning assembly includes a second motor (15), which is fixedly connected to the rear end of the weighing box (14). A lead screw (16) is fixedly connected to the output end of the second motor (15). A sliding plate (17) is threadedly connected to the outer ring of the lead screw (16), and a fixing plate (18) is fixedly connected to the bottom of the sliding plate (17).

3. The anti-caking type raw material vacuum dispensing mechanism according to claim 2, characterized in that: The rear end of the fixed plate (18) is fixedly connected to a scraper (19), and the top of the inner wall of the weighing box (14) is fixedly connected to a baffle (20).

4. The anti-caking type raw material vacuum dispensing mechanism according to claim 2, characterized in that: The weighing box (14) is fixedly connected to the top of a bracket (21), and a hydraulic cylinder (22) is fixedly connected to the top of the bracket (21). A sealing plate (23) is fixedly connected to the output end of the hydraulic cylinder (22).

5. The anti-caking type raw material vacuum dispensing mechanism according to claim 1, characterized in that: The weighing box (14) is fixedly connected to the rear end of the discharge port (24), and a pressure sensor (25) is fixedly connected to the bottom of the inner wall of the weighing box (14). The bottom of the weighing box (14) and the discharge port (24) are both fixedly connected to a second support column (26).

6. The anti-caking type raw material vacuum dispensing mechanism according to claim 1, characterized in that: A vacuum pump (27) is fixedly connected to one side of the weighing box (14), and the output end of the vacuum pump (27) passes through and is fixedly connected to the weighing box (14).

7. The anti-caking type raw material vacuum dispensing mechanism according to claim 1, characterized in that: The storage tank (1) is fixedly connected to a control panel (28) at its rear end.

8. The anti-caking type raw material vacuum dispensing mechanism according to claim 1, characterized in that: The storage tank (1) has a pipe (29) that is fixedly connected to the bottom of its rear end, and one end of the pipe (29) is fixedly connected to the weighing box (14).

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