Immunochromatography detection device

Abstract

The utility model discloses an immunochromatography detection device, which belongs to the technical field of immunochromatography and comprises a central block, bottom shells are arranged on the periphery of the central block, top covers are arranged on the tops of the four groups of bottom shells, observation windows are arranged on the top covers, a containing groove is formed in the central block, and the containing groove is communicated with the bottom shells. A containing groove is formed in the center block, a positioning structure is detachably installed on the containing groove, detection strips are further arranged between the bottom shell and the top cover, observation areas are arranged at the positions, corresponding to the observation windows, of the detection strips, a positioning block is arranged at one end of each detection strip, and a through groove is formed in the position, close to the bottom shell, of the center block. According to the immunochromatography detection device, four groups of different sample solutions can be detected at the same time, or one sample solution can be detected for four times at the same time, so that the efficiency of immunochromatography detection is improved, and the immunochromatography detection device can be conveniently disassembled and assembled through the arranged positioning structure, so that the immunochromatography detection device is conveniently cleaned, and the subsequent use effect is improved.

Description

Technical Field

[0001] This utility model relates to the field of immunochromatographic technology, specifically to an immunochromatographic detection device. Background Technology

[0002] Immunochromatography is a rapid diagnostic technique that emerged in the 1990s. Its principle is to first fix specific antibodies or antigens onto a certain zone of a nitrocellulose (NC) membrane. When one end of the dried NC membrane is immersed in a sample (usually urine, blood, or other bodily fluids), the sample will move along the membrane to the other end due to capillary action. When the sample moves to the area with labeled antibodies or antigens, the target antibody or antigen contained in the sample will specifically bind to the labeled antibody or antigen, and color development will occur through the labeling technique.

[0003] Existing immunochromatographic detection devices include a bottom shell and a top cover. An observation window is provided on the top cover, and a detection strip made of NC membrane material is placed between the bottom shell and the top cover. Antibodies or antigens are labeled on the detection strip, which can then perform a colorimetric reaction on the sample solution to be tested.

[0004] The above-mentioned technical conditions also have shortcomings: most existing immunochromatographic detection devices can only detect one or two types of sample solutions at the same time, or can only perform one or two sets of detections on one type of sample solution at the same time. Their utilization efficiency is not high and they are not conducive to long-term use.

[0005] Based on this, the present invention designs an immunochromatographic detection device to solve the above problems. Utility Model Content

[0006] The purpose of this invention is to provide an immunochromatographic detection device to solve the above-mentioned technical problems.

[0007] To achieve the above objectives, the present invention provides the following technical solution: an immunochromatographic detection device, comprising a central block, with bottom shells arranged around the central block, and top covers arranged on the top of each of the four bottom shells. An observation window is provided on the top cover. A receiving groove is provided inside the central block, and a positioning structure is detachably installed on the receiving groove. A detection strip is also provided between the bottom shells and the top covers. An observation area is provided on the detection strip at the corresponding position of the observation window. A positioning block is provided at one end of the detection strip. A through groove is provided on the central block near the bottom shell.

[0008] By adopting the above technical solution, four types of sample solutions can be detected simultaneously, or the same sample solution can be detected four times simultaneously, thereby improving the effect of immunochromatographic detection.

[0009] Preferably, the positioning structure includes a top plate, an alignment block fixedly connected to the top of the top plate, the alignment block being cross-shaped, a cross-shaped isolation block fixedly connected to the bottom of the top plate, a bottom plate fixedly connected to the bottom of the isolation block, and four sets of injection holes opened on the top plate, the four sets of injection holes being staggered with the four sides of the alignment block.

[0010] By adopting the above technical solution, the sample liquid is introduced into the positioning block from four sets of injection holes, and then a color reaction is carried out in the observation area on the detection strip. Finally, the sample is observed in the observation window.

[0011] Preferably, the four sides of the alignment block are each provided with a different color.

[0012] By adopting the above technical solution, it can be better distinguished.

[0013] Preferably, the center block is further provided with an alignment mark, which is adapted to the alignment block.

[0014] By adopting the above technical solution, the positioning structure can be easily assembled and disassembled.

[0015] Preferably, multiple limiting blocks are fixedly connected to both sides of the top of the bottom shell, and the limiting blocks are L-shaped.

[0016] By adopting the above technical solution, the limiting block can simultaneously limit the detection strip and the top cover.

[0017] Preferably, anti-slip ribs are fixedly provided on one side of the top surface of the top cover.

[0018] By adopting the above technical solution, the top cover can be easily disassembled and assembled.

[0019] In summary, this application has the following beneficial technical effects: by installing four sets of test strips, it is possible to simultaneously test four different sample solutions, or to perform four tests on one sample solution simultaneously, thereby improving the efficiency of immunochromatographic detection. Furthermore, the positioning structure allows for easy disassembly and assembly, facilitating cleaning and improving subsequent performance. Attached Figure Description

[0020] To more clearly illustrate the technical solutions of the embodiments of this utility model, the accompanying drawings used in the description of the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments of this utility model. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0021] Figure 1 This is a schematic diagram of the overall structure of this embodiment;

[0022] Figure 2 This is a top view illustrating the structure of this embodiment;

[0023] Figure 3 This is a schematic diagram of the positioning structure in this embodiment;

[0024] Figure 4 This is a schematic diagram of the disassembly and assembly of the detection strip in this embodiment.

[0025] The attached diagram lists the components represented by each number as follows:

[0026] 1. Center block; 2. Bottom shell; 3. Top cover; 4. Observation window; 5. Receiving groove; 6. Positioning structure; 61. Top plate; 62. Alignment block; 63. Isolation block; 64. Bottom plate; 65. Sample injection hole; 7. Anti-slip ribs; 8. Detection strip; 9. Positioning block; 10. Through groove; 11. Limiting block; 12. Alignment mark. Detailed Implementation

[0027] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those skilled in the art without creative effort are within the protection scope of the present utility model.

[0028] The following is in conjunction with the appendix Figure 1-4 This application will be described in further detail.

[0029] An immunochromatographic detection device includes a central block 1, with bottom shells 2 arranged around the central block 1, and top covers 3 arranged on the top of each of the four bottom shells 2. The top covers 3 are installed on the top of the bottom shells 2 by snap-fit. An observation window 4 is provided on the top cover 3. A receiving groove 5 is opened inside the central block 1, and a positioning structure 6 is detachably installed on the receiving groove 5. A detection strip 8 is also arranged between the bottom shells 2 and the top covers 3. An observation area is arranged on the detection strip 8 at the corresponding position of the observation window 4. The observation area contains an antigen or antibody with a color mark. A positioning block 9 is arranged at one end of the detection strip 8. The detection strip 8 and the positioning block 9 are integrally formed NC membranes. Through capillary action, the sample liquid can move on the detection strip 8 towards the end away from the positioning block 9, thereby performing a color reaction in the observation area on the detection strip 8. A through groove 10 is opened on the central block 1 near the bottom shell 2. The detection strip 8 can pass through the through groove 10, so that the positioning block 9 can enter below the sample injection port 65.

[0030] Furthermore, the positioning structure 6 includes a top plate 61, on which an alignment block 62 is fixedly connected. The alignment block 62 is cross-shaped, which can align the installation of the positioning structure 6 and prevent interference when injecting different sample solutions. A cross-shaped isolation block 63 is fixedly connected to the bottom of the top plate 61, allowing the four sets of positioning blocks to be positioned inside the isolation block 63, thereby increasing the effectiveness of use. A bottom plate 64 is fixedly connected to the bottom of the isolation block 63. The bottom plate 64 is detachably installed on the center block 1, one method being installation by bolts, which allows for easy disassembly. Four sets of injection holes 65 are provided on the top plate 61, and the four sets of injection holes 65 are staggered with the four sides of the alignment block 62 (e.g., Figure 2 As shown, the injection hole 65 is located directly above the positioning block 9 after the test strip 8 is installed, through which the sample liquid is dripped onto the positioning block 9 and the test strip 8.

[0031] Furthermore, multiple limiting blocks 11 are fixedly connected to both sides of the top of the bottom shell 2. The limiting blocks 11 are L-shaped, with their outer edges able to abut against the side of the detection strip 8, and their inner edges able to engage with the top cover 3.

[0032] Furthermore, an anti-slip rib 7 is fixedly provided on one side of the top surface of the top cover 3, which can easily push the top cover 3 out of the bottom shell 2, thereby facilitating the disassembly and assembly of the detection strip 8.

[0033] Furthermore, the four sides of the alignment block 62 are each decorated with different colors, such as red, yellow, blue, and green, to better distinguish them.

[0034] Furthermore, a alignment mark 12 is provided on the center block 1, which is adapted to the alignment block 62.

[0035] The implementation principle of this embodiment is as follows: When in use, the film 64 is fixedly installed on the center block 1, and then one side of the alignment block 62 is aligned with the alignment mark 12. Then, four sets of detection strips 8 are inserted, with one end of the strip with the positioning block 9 inserted into the interior of the center block 1 through the through groove 10, so that the positioning block 9 can enter the slot between the isolation blocks 63. At this time, the detection strip 8 is located between multiple limiting blocks 11, and then the top cover 3 is locked by the limiting blocks 11. Then, four different sample liquids are injected into the four sets of injection holes 65. After the color reaction is completed, the displayed color can be observed through the observation window 4, thereby realizing the simultaneous detection of four different sample liquids, and also the simultaneous four detections of one sample liquid, which can effectively improve the accuracy of detection.

[0036] In the description of this utility model, it should be understood that the terms "coaxial", "bottom", "one end", "top", "middle", "other end", "upper", "side", "top", "inner", "front", "center", "both ends", etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the drawings. They are only for the convenience of describing this utility model and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on this utility model.

[0037] In this utility model, unless otherwise explicitly specified and limited, the terms "installation", "setting", "connection", "fixing", "screw connection", etc., should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral part; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; they can refer to the internal connection of two components or the interaction between two components. Unless otherwise explicitly limited, those skilled in the art can understand the specific meaning of the above terms in this utility model according to the specific circumstances.

[0038] Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the present invention, the scope of which is defined by the appended claims and their equivalents.

Claims

1. An immunochromatographic detection device, comprising a central block (1), characterized in that: The central block (1) is surrounded by a bottom shell (2), and a top cover (3) is provided on the top of each of the four bottom shells (2). An observation window (4) is provided on the top cover (3). A receiving groove (5) is provided inside the central block (1). A positioning structure (6) is detachably installed on the receiving groove (5). A detection strip (8) is provided between the bottom shell (2) and the top cover (3). An observation area is provided on the detection strip (8) and at the corresponding position of the observation window (4). A positioning block (9) is provided at one end of the detection strip (8). A through groove (10) is provided on the central block (1) near the bottom shell (2).

2. The immunochromatographic detection device according to claim 1, characterized in that: The positioning structure (6) includes a top plate (61), an alignment block (62) is fixedly connected to the top of the top plate (61), the alignment block (62) is cross-shaped, a cross-shaped isolation block (63) is fixedly connected to the bottom of the top plate (61), a bottom plate (64) is fixedly connected to the bottom of the isolation block (63), and four sets of injection holes (65) are opened on the top plate (61), the four sets of injection holes (65) are staggered with the four sides of the alignment block (62).

3. The immunochromatographic detection device according to claim 2, characterized in that: The four sides of the alignment block (62) are each decorated with a different color.

4. The immunochromatographic detection device according to claim 2, characterized in that: The center block (1) is also provided with an alignment mark (12), which is adapted to the alignment block (62).

5. The immunochromatographic detection device according to claim 1, characterized in that: Multiple limiting blocks (11) are fixedly connected to both sides of the top of the bottom shell (2), and the limiting blocks (11) are L-shaped.

6. The immunochromatographic detection device according to claim 1, characterized in that: Anti-slip ribs (7) are fixedly provided on one side of the top surface of the top cover (3).

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