Full-automatic tissue slice preparation machine

The fully automated tissue sectioning machine solves the problems of low efficiency and high risk of contamination in traditional sectioning equipment by utilizing the synergistic effect of the drive component and the sectioning component, thus achieving automated and efficient sectioning.

CN224275209UActive Publication Date: 2026-05-26KENTING MEDICAL TECHNOLOGY (SUZHOU) CO LTD
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
KENTING MEDICAL TECHNOLOGY (SUZHOU) CO LTD
Filing Date
2025-07-17
Publication Date
2026-05-26

AI Technical Summary

Technical Problem

In existing technologies, traditional tissue sectioning equipment suffers from problems such as low efficiency, uneven section thickness, and high risk of sample contamination.

Method used

The fully automated tissue sectioning machine utilizes the synergistic action of the drive and sectioning components to achieve an automated tissue sectioning process. The combination of the arc-shaped sectioning pusher and the electric push rod ensures sectioning accuracy and efficiency.

Benefits of technology

It has achieved an automated tissue slicing process, improved slice thickness uniformity, reduced the risk of sample contamination, and enhanced slice adhesion efficiency.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model relates to a full-automatic tissue slice preparation machine which comprises a base, stand columns are arranged at the four corners of the top end of the base, the top ends of the stand columns are jointly provided with a top frame, and two guide rails are arranged at the bottom end of the top frame. The utility model relates to the technical field of tissue slicing equipment. According to the full-automatic tissue slice preparation machine, a supporting plate is pushed through a driving assembly, a detected body is pushed to make contact with an inserting plate, after the inserting plate makes contact with the detected body, part of tissue of the detected body can be embedded into an embedding groove, and an electric push rod pushes a slice push broach to move to cut the detected body inserted into the embedding groove; the tissue stays at the top end of the section push-type broach, the section push-type broach is arranged in an arc shape, so that the cut tissue can be pushed upwards, the tissue is pushed upwards through the upper guide ring to make contact with the slide, then the slide is manually taken down, and then the purpose of automatically preparing the section is achieved.
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Description

Technical Field

[0001] This utility model relates to the technical field of tissue sectioning equipment, and in particular to a fully automatic tissue sectioning preparation machine. Background Technology

[0002] Tissue sectioning involves taking small pieces of diseased or suspected diseased tissue from a patient using medical methods. After processing, these tissues are prepared into sections for observation and analysis under a microscope to aid in disease diagnosis.

[0003] Traditional tissue sectioning requires manual operation of microtome and forceps, resulting in low efficiency, uneven section thickness, and the risk of sample contamination. Existing electric microtome equipment relies on servo motors and sensors, which are costly and complex to maintain. Utility Model Content

[0004] In view of the shortcomings of the existing technology, the purpose of this utility model is to provide a fully automatic tissue section preparation machine to solve the technical problems mentioned in the background.

[0005] The above-mentioned technical objective of this utility model is achieved through the following technical solution:

[0006] A fully automated tissue section preparation machine, comprising:

[0007] The base has columns at its four corners, and a top frame is set at the top of the columns. Two guide rails are set at the bottom of the top frame, and a horizontal rod is slidably mounted on the two guide rails. Control components for driving the horizontal rod to move are set at the corners of the top frame. A slicing slider is slidably mounted inside the horizontal rod, and a slicing component for controlling the movement of the slicing slider is set at the end of the horizontal rod.

[0008] The bottom of the slide slider is equipped with an insert plate, the inside of which is a slide mounting groove. The top of the slide mounting groove is equipped with an electric suction cup for adsorbing the slides that hold the tissue slides. The bottom of the insert plate is provided with an embedding groove, and the bottom of the slide mounting groove is equipped with a slide pusher.

[0009] A tray is installed on the top of the base, and drive components are installed on both sides of the tray to drive the tray to lift and lower.

[0010] Furthermore, the bottom surface of the slicing pusher is in contact with the bottom surface of the slide mounting groove, the blade of the slicing pusher is arc-shaped, and the cutting edge is in contact with the bottom surface of the slide mounting groove.

[0011] Furthermore, the end of the slicing pusher is provided with an electric push rod for pushing the slicing pusher to move, and the top of the slicing pusher is provided with an upper guide ring, which is arc-shaped.

[0012] Furthermore, a lifting platform is provided at the upper end of the pallet, and an anti-slip groove is provided on the upper surface of the lifting platform.

[0013] Furthermore, the control component includes:

[0014] A fixed bracket is fixedly connected to the bottom end of the top frame. A drive motor is installed inside the fixed bracket. A control screw is fixedly installed at the shaft of the drive motor. The control screw passes through one end of the horizontal rod and is threadedly engaged with the horizontal rod.

[0015] Furthermore, the slicing component includes:

[0016] Two connecting frames are fixedly installed at both ends of the horizontal rod. A positioning screw is provided between the two connecting frames, and the inside of the slicing slider is provided with a screw hole that matches the positioning screw.

[0017] In summary, this utility model has at least one of the following beneficial technical effects:

[0018] 1. This fully automatic tissue section preparation machine uses a drive assembly to push a tray, which advances the specimen to contact the insert plate. After the insert plate contacts the specimen, part of the specimen's tissue is embedded in the insertion groove. An electric push rod drives the section pusher to cut the specimen inserted into the insertion groove, so that the tissue stays at the top of the section pusher. Since the section pusher is arc-shaped, it can push the cut tissue upward. The upper guide ring pushes the tissue upward to contact the glass slide, which is then manually removed, thus achieving the purpose of automatic section preparation.

[0019] 2. This fully automatic tissue sectioning machine features an arc-shaped cutting edge design on the sectioning pusher, which allows it to smoothly push the tissue upwards during cutting. The cutting edge fits snugly against the bottom surface of the slide mounting groove to ensure cutting accuracy. The machine is driven by an electric pusher to achieve precise sectioning action. In conjunction with the arc-shaped upper guide ring and the sectioning pusher, the cut tissue is further guided to the surface of the slide. Its arc design reduces tissue residue and improves sectioning adhesion efficiency. Attached Figure Description

[0020] To more clearly illustrate the technical solutions of the embodiments of this utility model, the accompanying drawings used in the description of the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments of this utility model. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0021] Figure 1 This is a schematic diagram of the structure of a fully automatic tissue section preparation machine according to the present invention.

[0022] Figure 2This is a schematic diagram of the control components of a fully automatic tissue section preparation machine according to the present invention.

[0023] Figure 3 This is a schematic diagram of the slicing assembly of a fully automatic tissue slicing machine according to the present invention.

[0024] Figure 4 This is a schematic diagram of the slicing slider and slicing pusher of a fully automatic tissue sectioning machine according to the present invention.

[0025] In the diagram, 1. Base; 2. Column; 3. Top frame; 4. Guide rail; 5. Horizontal bar; 6. Control assembly; 61. Fixed bracket; 62. Drive motor; 63. Control screw; 7. Slicing slider; 8. Slicing assembly; 81. Connecting frame; 82. Positioning screw; 83. Screw hole; 9. Insert plate; 10. Slide mounting slot; 11. Electric suction cup; 12. Embedding slot; 13. Slicing pusher; 131. Electric push rod; 132. Upper guide ring; 14. Support plate; 15. Drive assembly; 16. Lifting platform. Detailed Implementation

[0026] The present invention will be further described in detail below with reference to the accompanying drawings.

[0027] Example:

[0028] Reference Figure 1 - Figure 4 This utility model discloses a fully automatic tissue section preparation machine, comprising:

[0029] The base 1 has four uprights 2 at its top corners, and a top frame 3 is mounted on the top of each upright 2. The base 1, uprights 2, and top frame 3 together form a three-dimensional square frame structure. Two guide rails 4 are provided at the bottom of the top frame 3. A transverse rod 5 is mounted on these two symmetrically arranged guide rails 4. A control component 6 controls the movement of the transverse rod 5 along the guide rails 4, and a slicing component 8 controls the movement of the slicing slider 7 to facilitate sample extraction from different surfaces of the subject. The transverse rod 5 is slidably mounted on the two guide rails 4. Control components 6 are located at the corners of the top frame 3 to drive the movement of the transverse rod 5. Specifically, when the transverse rod 5 is driven to move by the control component 6, the movement is controlled by... The drive motor 62 drives the control screw 63 to rotate. Since the control screw 63 is threadedly engaged with the transverse rod 5, the transverse rod 5 can be effectively driven to slide laterally during the rotation of the control screw 63. The transverse rod 5 has a sliding slider 7 inside, and a slicing assembly 8 for controlling the movement of the slicing slider 7 is provided at the end of the transverse rod 5. Specifically, when the slicing slider 7 is moved by controlling the slicing assembly 8, the positioning screw 82 is rotated by the servo motor set inside the connecting frame 81. Since the positioning screw 82 is threadedly engaged with the screw hole 83 opened inside the slicing slider 7, the rotation of the positioning screw 82 can achieve the purpose of driving the slicing slider 7 to move.

[0030] In summary, the movement of the slice slider 7 on the plane can be effectively controlled by the control component 6 and the slicing component 8.

[0031] The slide slide slider 7 has an insert plate 9 at its bottom end, and a slide mounting groove 10 is provided inside the insert plate 9. An electric suction cup 11 is provided at the top of the slide mounting groove 10 to hold the tissue slide. An embedding groove 12 is provided at the bottom end of the insert plate 9, and a slide pusher 13 is provided at the bottom of the slide mounting groove 10. By using the insert plate 9, as the slide slide slider 7 moves, the insert plate 9 is moved to different positions above the subject, and at this time, the slide is inserted into the slide mounting groove 10 and fixed by the electric suction cup 11. Then, the drive assembly 15... Push the tray 14 to advance the specimen to contact the insert plate 9. After the insert plate 9 contacts the specimen, part of the specimen's tissue will be embedded in the embedding groove 12. The electric push rod 131 pushes the slide pusher 13 to move and cut the specimen inserted into the embedding groove 12, so that the tissue stays at the top of the slide pusher 13. Since the slide pusher 13 is arc-shaped, it can push the cut tissue upward and push the tissue upward through the upper guide ring 132 so that it contacts the glass slide. Then the glass slide is removed manually, thereby achieving the purpose of automatic slide preparation.

[0032] A support plate 14 is provided on the top of the base 1, and drive components 15 are provided on both sides of the support plate 14 for driving the support plate 14 to move up and down. The drive components 15 include a lifting motor and a lifting screw. The lifting screw is fixedly connected to the motor shaft of the lifting motor, and the lifting screw is threadedly engaged with the support plate 14. Therefore, when the lifting motor rotates, it can control the support plate 14 to move up and down. Guide rods are provided on both sides of the base 1 that pass through the support plate 14 and are slidably connected to the support plate 14.

[0033] In this embodiment, the guide rail 4 system is integrated through a square frame structure. The drive motor 62 of the control component 6 drives the control screw 63 to rotate, so that the horizontal rod 5 moves horizontally along the guide rail 4. At the same time, the slicing component 8 achieves precise longitudinal positioning of the slicing slider 7 by driving the positioning screw 82 through the servo motor, thus forming two-dimensional planar motion control.

[0034] During the slicing process, after the insertion groove 12 at the bottom of the insert plate 9 comes into contact with the subject, the electric push rod 131 drives the arc-shaped slicing pusher 13 to cut the tissue. Combined with the upper guide ring 132, the tissue is pushed to the surface of the glass slide fixed by the electric suction cup 11. The support plate 14 adjusts the height of the subject through the lifting motor and screw mechanism, and finally realizes the fully automated process from positioning, slicing to sample transfer.

[0035] In a further preferred embodiment of this utility model, such as Figure 4 As shown, the bottom surface of the slicing pusher 13 is in contact with the bottom surface of the slide mounting groove 10, and the blade of the slicing pusher 13 is arc-shaped, with the cutting edge in contact with the bottom surface of the slide mounting groove 10.

[0036] In this embodiment, the arc-shaped cutting edge design of the slicing pusher 13 allows it to push the tissue upward during cutting. The cutting edge fits against the bottom surface of the slide mounting groove 10 to ensure cutting accuracy. The precise slicing action is achieved by driving the electric push rod 131.

[0037] In a further preferred embodiment of this utility model, such as Figure 4 As shown, the end of the slicing pusher 13 is provided with an electric push rod 131 for pushing the slicing pusher 13 to move, and the top of the slicing pusher 13 is provided with an upper guide ring 132, which is arc-shaped.

[0038] In this embodiment, the arc-shaped upper guide ring 132 is linked with the slide pusher 13 to further guide the cut tissue to the surface of the glass slide. Its arc design reduces tissue residue and improves the adhesion efficiency of the slide.

[0039] In a further preferred embodiment of this utility model, such as Figure 2 As shown, a lifting platform 16 is provided at the upper end of the pallet 14, and an anti-slip groove is provided on the upper surface of the lifting platform 16.

[0040] In this embodiment, the lifting platform 16 on the tray 14 fixes the specimen through the anti-slip groove, and the lifting screw structure of the drive assembly 15 achieves stable vertical displacement, ensuring uniform contact pressure between the tissue and the insertion plate 9.

[0041] In a further preferred embodiment of this utility model, such as Figure 2 As shown, the control component 6 includes:

[0042] A fixed bracket 61 is fixedly connected to the bottom end of the top frame 3. A drive motor 62 is installed inside the fixed bracket 61. A control screw 63 is fixedly installed at the shaft of the drive motor 62. The control screw 63 passes through one end of the transverse rod 5 and is threadedly engaged with the transverse rod 5.

[0043] In this embodiment, a drive motor 62 is used to drive the control screw 63 to rotate. The rotational motion is converted into linear movement of the transverse rod 5 by utilizing the thread engagement principle, thereby achieving horizontal adjustment of the slice position.

[0044] In a further preferred embodiment of this utility model, such as Figure 3 As shown, the slicing component 8 includes:

[0045] Two connecting frames 81 are fixedly installed at both ends of the horizontal rod 5. A positioning screw 82 is provided between the two connecting frames 81, and a screw hole 83 that cooperates with the positioning screw 82 is opened inside the slicing slider 7.

[0046] In this embodiment, the positioning screw 82 is driven to rotate by a servo motor, so that the slice slider 7 moves along the screw hole 83 inside the transverse rod 5 to complete precise longitudinal positioning and form a two-dimensional planar motion control system.

[0047] The embodiments described herein are preferred embodiments of this utility model and are not intended to limit the scope of protection of this utility model. Therefore, all equivalent changes made to the structure, shape, and principle of this utility model should be included within the scope of protection of this utility model.

Claims

1. A fully automated tissue section preparation machine, characterized in that, Including: The base (1) has four columns (2) at its top corners. The top of the columns (2) is provided with a top frame (3). The bottom of the top frame (3) is provided with two guide rails (4). The two guide rails (4) are slidably provided with a horizontal rod (5). The corners of the top frame (3) are provided with control components (6) for driving the horizontal rod (5) to move. The inside of the horizontal rod (5) is provided with a slicing slider (7). The end of the horizontal rod (5) is provided with a slicing component (8) for controlling the movement of the slicing slider (7). The bottom end of the slide slider (7) is provided with an insert plate (9), the inside of the insert plate (9) is provided with a slide mounting groove (10), the top of the inside of the slide mounting groove (10) is provided with an electric suction cup (11) for adsorbing the slides that carry the tissue slides, the bottom end of the insert plate (9) is provided with an embedding groove (12), and the bottom of the inside of the slide mounting groove (10) is provided with a slide pusher (13); A tray (14) is provided on the top of the base (1), and drive components (15) are provided on both sides of the tray (14) for driving the tray (14) to rise and fall.

2. The fully automated tissue sectioning machine according to claim 1, characterized in that, The bottom surface of the slicing pusher (13) is in contact with the bottom surface of the slide mounting groove (10). The blade of the slicing pusher (13) is arc-shaped and the cutting edge is in contact with the bottom surface of the slide mounting groove (10).

3. The fully automated tissue sectioning machine according to claim 2, characterized in that, The end of the slicing pusher (13) is provided with an electric push rod (131) for pushing the slicing pusher (13) to move. The top of the slicing pusher (13) is provided with an upper guide ring (132), which is arc-shaped.

4. The fully automated tissue sectioning machine according to claim 3, characterized in that, The upper end of the pallet (14) is provided with a lifting platform (16), and the upper surface of the lifting platform (16) is provided with anti-slip grooves.

5. The fully automated tissue section preparation machine according to claim 4, characterized in that, The control component (6) includes: A fixed bracket (61) is fixedly connected to the bottom end of the top frame (3). A drive motor (62) is installed inside the fixed bracket (61). A control screw (63) is fixedly installed at the shaft of the drive motor (62). The control screw (63) passes through one end of the transverse rod (5) and is threadedly engaged with the transverse rod (5).

6. The fully automated tissue sectioning machine according to claim 5, characterized in that, The slicing component (8) includes: Two connecting frames (81) are fixedly installed at both ends of the horizontal rod (5). A positioning screw (82) is provided between the two connecting frames (81), and a screw hole (83) that matches the positioning screw (82) is opened inside the slice slider (7).