A rapid detection kit for Helicobacter pylori using a pressure-controlled air-blowing method

Abstract

This invention discloses a pressure-stabilized air-blowing reagent kit for rapid detection of Helicobacter pylori. It comprises an air bladder for storing samples and a reagent kit communicating with the air bladder for sample detection. Two support plates are located on the bottom of the kit, with a squeezing component positioned between them to compress the air bladder and expel the sample from the air bladder into the kit. The squeezing component includes a hinge shaft rotatably connected to the support plates at its end. A squeezing plate is fixedly mounted on the hinge shaft, and a driving component is provided on the squeezing plate. The driving component drives the squeezing plate to rotate around the hinge shaft, thereby squeezing the air bladder from the bottom of the kit. This solves the problem in existing technologies where the sample inside the air bladder cannot be squeezed out to contact the detection plate at a certain standard, thus affecting the validity and reliability of the detection results.

Description

Technical Field

[0001] This utility model relates to the field of colony detection technology, specifically to a pressure-controlled air-blowing reagent kit for rapid detection of Helicobacter pylori. Background Technology

[0002] Helicobacter pylori is a common gastrointestinal bacterium that can cause diseases such as gastritis, peptic ulcers, and stomach cancer. One rapid method for detecting Helicobacter pylori is using a breath test kit. This non-invasive and simple test relies on the urease activity produced by Helicobacter pylori in the stomach. During the test, the patient drinks a solution containing labeled urea on an empty stomach and then exhales a sample of the air from their mouth. If the sample contains Helicobacter pylori, it will break down the urea, producing carbon dioxide, thus increasing the carbon dioxide concentration in the sample. The test usually takes only a few minutes and can be performed at home or in a clinic. Although the breath test kit is a simple and easy method, its accuracy can be affected by air humidity. Therefore, a rapid Helicobacter pylori breath test kit has been developed (see Reference 1).

[0003] Reference 1: Chinese patent document with patent publication number CN216669820U.

[0004] Reference 1 discloses a rapid detection kit for Helicobacter pylori using an air-blowing method, comprising a shell, a groove on the upper surface of the shell, a detection plate fixedly connected to the inner surface of the groove for detecting carbon dioxide content, an observation hole on the upper surface of the detection plate, a first conduit fixedly connected to the left surface of the shell, the right end of the first conduit extending to the lower side of the detection plate, an air bladder connected to the first conduit, and absorbent cotton fixedly connected to the surface of the air bladder for drying the test sample to reduce the impact of excessive sample humidity on the detection effect.

[0005] However, the kit described in Reference 1 relies on manual squeezing of the balloon to dispense samples. This manual squeezing method makes the sample dispensing speed susceptible to interference from numerous external factors. Specifically, different users have varying degrees of force and speed during manual squeezing, making it difficult to guarantee consistency in each squeeze. Therefore, the sample dispensing speed fluctuates significantly, making it difficult to maintain a stable, standardized range. When the sample dispensing speed cannot be maintained at a certain standard, it directly leads to the sample failing to achieve standard contact with the detection plate. For the detection plate to accurately detect carbon dioxide levels, it is essential that the sample maintains contact with the sample within a certain standard. Due to these problems, the accuracy of this kit in detecting Helicobacter pylori is severely negatively impacted, and the reliability and validity of the test results are significantly reduced. Utility Model Content

[0006] The purpose of this invention is to solve the problem in the prior art that the sample inside the air bladder cannot be squeezed out to contact the detection plate according to a certain standard, thus affecting the validity and reliability of the detection results, and to provide a pressure-stabilized air blowing kit for rapid detection of Helicobacter pylori.

[0007] To address the shortcomings of the aforementioned technical problems, the present invention adopts the following technical solution: a pressure-stabilized air-blowing reagent kit for rapid detection of Helicobacter pylori, which has an air bladder for storing samples and a reagent kit connected to the air bladder for detecting samples. The bottom surface of the reagent kit is provided with two support plates, and a squeezing component is provided between the two support plates to squeeze the air bladder so that the sample inside the air bladder is output into the reagent kit.

[0008] The extrusion assembly includes a hinge shaft whose end is rotatably connected to a support plate. An extrusion plate is fixedly mounted on the hinge shaft. A driving component is mounted on the extrusion plate. The driving component is used to drive the extrusion plate to rotate around the hinge shaft to cooperate with the bottom surface of the reagent kit to extrude the airbag.

[0009] As a further optimization of the pressure-stabilized air-blowing reagent kit for rapid detection of Helicobacter pylori of this utility model: the driving component includes a snap-fit ​​bracket fixed on the reagent kit and two connecting blocks disposed on the extrusion plate. The snap-fit ​​bracket snaps into a mating post, and the mating post and the connecting blocks are connected by a driving spring.

[0010] As a further optimization of the pressure-stabilized air-blowing reagent kit for rapid detection of Helicobacter pylori of this utility model: the driving component includes two torsion springs sleeved on the hinge shaft, the torsion springs being located between the extrusion plate and the support plate to drive the extrusion plate to rotate.

[0011] As a further optimization of the pressure-stabilized air-blowing reagent kit for rapid detection of Helicobacter pylori of this utility model: when the extrusion plate is attached to the reagent kit, the outer edge of the extrusion plate opposite to the hinge axis is set beyond the bottom surface of the reagent kit.

[0012] As a further optimization of the pressure-stabilized air-blowing reagent kit for rapid detection of Helicobacter pylori of this utility model: both of the support plates are provided with positioning grooves, the positioning grooves include vertically arranged vertical grooves and inlet grooves connected to the vertical grooves, the inlet grooves are arranged through the side of the support plate opposite to the hinge axis.

[0013] As a further optimization of the pressure-stabilized air-blowing reagent kit for rapid detection of Helicobacter pylori of this utility model: the reagent kit includes a support plate and a groove opened on the top surface of the support plate. The groove is connected to a connecting pipe provided on the support plate, and a detection plate is provided in the groove. An observation hole is opened at the center of the detection plate.

[0014] As a further optimization of the pressure-stabilized air-blowing reagent kit for rapid detection of Helicobacter pylori of this utility model: a valve is provided on the connecting pipe.

[0015] As a further optimization of the pressure-stabilized air-blowing reagent kit for rapid detection of Helicobacter pylori of this utility model: the air bladder is provided with a transmission tube and a one-way valve, the transmission tube and the one-way valve are symmetrically arranged along the length of the air bladder, and the transmission tube is used to communicate with the reagent kit to output samples.

[0016] Compared with the prior art, the present invention has the following beneficial effects:

[0017] This invention positions the airbag below the reagent kit by setting a positioning groove. At the same time, a squeezing component, which is set below the reagent kit and cooperates with the positioning groove, squeezes the airbag so that the sample in the airbag is only affected by the squeezing force of the squeezing component when the sample is output. This allows the sample in the airbag to be output according to a certain standard, that is, the detection plate can contact the sample for detection according to a certain standard, thereby making the test results of the reagent kit have high reliability and effectiveness. Attached Figure Description

[0018] Figure 1 This is a front view structural diagram of Embodiment 1 of the present utility model;

[0019] Figure 2 This is a schematic diagram of the usage state structure of Embodiment 1 of this utility model;

[0020] Figure 3 This is a front view structural diagram of Embodiment 2 of the present invention;

[0021] Figure 4 This is a schematic diagram of the usage state structure of Embodiment 2 of this utility model;

[0022] The markings in the diagram are: 1. Support plate; 2. Positioning groove; 201. Inlet groove; 202. Vertical groove; 3. Extrusion assembly; 301. Extrusion plate; 302. Drive component; 3021. Connecting block; 3022. Drive spring; 3023. Snap-fit ​​bracket; 3024. Mating column; 3025. Torsion spring; 303. Hinge shaft; 4. Reagent kit; 401. Connecting tube; 402. Valve; 403. Groove; 404. Detection plate; 405. Observation hole; 406. Support plate; 5. Airbag; 501. Transfer tube; 502. One-way valve. Detailed Implementation

[0023] To better understand this utility model, the following embodiments further illustrate the content of this utility model, but the content of this utility model is not limited to the following embodiments.

[0024] <Example 1>

[0025] like Figure 1As shown, a pressure-controlled air-blowing kit for rapid detection of Helicobacter pylori, similar to existing technologies, includes an air bladder 5 for storing samples and a kit 4 for introducing samples into the air bladder 5 for testing. The air bladder 5 is equipped with a one-way valve 502 and a transfer tube 501, which are symmetrically arranged along the length of the air bladder 5. The one-way valve 502 facilitates the blowing of samples into and storing them inside the air bladder 5. The transfer tube 501 is a flexible tube that can be snapped into the connecting tube 401 included in the kit 4 to complete the connection. The connecting pipe 401 is equipped with a valve 402, which can work with the one-way valve 502 to seal the sample in the airbag 5 for storage. The connecting pipe 401 is fixedly mounted on the support plate 406 and communicates with the groove 403 opened on the support plate 406. The groove 403 is equipped with a detection plate 404. When the valve 402 is opened, the gas in the airbag 5 diffuses into the groove 403 and contacts the detection plate 404 for detection. At the same time, the user can observe through the observation hole 405 opened on the detection plate 404 to obtain the detection results.

[0026] Unlike existing technologies, the bottom surface of the support plate 406, i.e. the side of the support plate 406 facing away from the groove 403, is provided with two support plates 1. The two support plates 1 are arranged axially along the connecting pipe 401. Both support plates 1 have positioning grooves 2. The positioning grooves 2 allow the one-way valve 502 and the transmission pipe 501 to be inserted to position the airbag 5. This allows the extrusion assembly 3 on the two support plates 1 to extrude the airbag 5, so that after the valve 402 is opened, the sample in the airbag 5 continuously and consistently enters the groove 403 and contacts the detection plate 404, thereby ensuring that the detection results have high reliability and effectiveness. Specifically, the extrusion assembly 3 includes hinge shafts 303 rotatably mounted on two support plates 1 at both ends. The gap between the hinge shafts 303 and the support plates 406 is 1.2 times the thickness of the airbag 5 in its uninflated state. An extrusion plate 301 corresponding to the positioning groove 2 is fixedly mounted on the hinge shafts 303. A drive member 302 is provided on the extrusion plate 301 to drive it to rotate and extrude the airbag 5. When the drive member 302 drives the extrusion plate 301 to rotate to a horizontal state, the airbag 5 in the airbag 5 will be completely extruded. Figure 2As shown, during the process of the extrusion plate 301 being driven by the driving component 302 to flip and extrude the airbag 5, the positioning groove 2 will cooperate with the positioning airbag 5 to prevent the airbag 5 from shifting. Subsequently, the sample can be fully output while maintaining a certain standard to contact the detection plate 404, thus ensuring high reliability and effectiveness of the detection results. The driving component 302 includes two connecting blocks 3021 fixedly disposed on the ends of the extrusion plate 301 away from the hinge shaft 303. The two connecting blocks 3021 are connected to a mating post 3024 by a driving spring 3022. The mating post 3024 cooperates with a snap-fit ​​bracket 3023 fixedly disposed on the support plate 406. The snap-fit ​​bracket 3023 is disposed corresponding to the end of the extrusion plate 301 away from the hinge shaft 303. When it is necessary to insert or replace the airbag 5, the mating post 3024 can be pulled to overcome the tension of the driving spring 3022, causing the mating post 3024 to be removed from the snap-fit ​​bracket 3023. Subsequently, the extrusion plate 301 will... Once the restraint is released and the device flips downwards, the user can then remove the airbag 5 containing the tested sample from the positioning slot 2 and place the airbag 5 containing the sample into the positioning slot 2. The user then resets the mating post 3024 to the snap-fit ​​bracket 3023. Afterwards, the pull block is tightened by the drive spring 3022, so that the compression plate 301 has a relatively continuous and linearly changing upward flipping force. This allows the compression plate 301 to work with the support plate 406 to maintain a certain standard of compression of the airbag 5, so that the sample can be output at a certain standard, and the user can obtain effective test results.

[0027] The positioning groove 2 includes a vertically arranged vertical groove 202 and an inlet groove 201 communicating with the vertical groove 202. The inlet groove 201 is obliquely arranged and passes through the side of the support plate 1 opposite to the hinge shaft 303. The inlet groove 201 facilitates the placement of the airbag 5 between the compression plate 301 and the support plate 406 by the operator, allowing the transmission pipe 501 on the airbag 5 to pass through the support plate 1 and connect to the connecting pipe 401. At the same time, it can also guide the airbag 5 in conjunction with the transmission pipe 501 and the one-way valve 502, so that the operator can quickly and appropriately place the airbag 5. The sample is placed between the extrusion plate 301 and the support plate 406 for subsequent extrusion. After being guided by the inlet groove 201, the transmission pipe 501 and the one-way valve 502 can enter the corresponding vertical grooves 202 to limit the airbag 5. This reduces the possibility that the airbag 5 may leak out from the side of the extrusion plate 301 without the hinge 303 during the process of the extrusion plate 301 being tightened and extruded by the two drive springs 3022, or affect the contraction of the drive springs 3022. This ensures that the sample in the airbag 5 maintains a certain standard output.

[0028] <Example 2>

[0029] like Figure 3 and Figure 4As shown, this embodiment is basically the same as embodiment 1. The difference from embodiment 1 is that the driving component 302 includes two torsion springs 3025 sleeved on the hinge shaft 303. The two ends of the torsion springs 3025 are respectively connected to the extrusion plate 301 and the support plate 1. When the airbag 5 needs to be placed between the extrusion plate 301 and the support plate 406, the extrusion plate 301 can be pulled directly, causing the extrusion plate 301 to overcome the torsional force of the two torsion springs 3025 and flip downward. Then, the airbag 5 can be stably placed into the extrusion plate 406 with the cooperation of the positioning groove 2. When the valve 402 on the connecting pipe 401 is opened for testing, the two torsion springs 3025, supported by the two support plates 1, drive the compression plate 301 to maintain a slight compression of the air bladder 5. This ensures that the compression plate 301 maintains a certain standard of compression of the air bladder 5, allowing the sample in the air bladder 5 to be continuously and consistently output. Subsequently, the sample can continuously and consistently enter the groove 403 and be contacted by the detection plate 404 to obtain effective test results. Specifically, when the detection plate 404 is kept horizontal, the end of the detection plate 404 away from the hinge shaft 303 extends beyond the support plate 406, making it easier for the operator to push the compression plate 301 to overcome the torque of the torsion springs 3025 and flip it down, so that the operator can change the air bladder 5 containing different samples.

[0030] The specific embodiments of this utility model have been described above. It should be understood that this utility model is not limited to the specific embodiments described above, and those skilled in the art can make various modifications or variations within the scope of the claims, which do not affect the substantive content of this utility model.

Claims

1. A pressure-controlled air-blowing kit for rapid detection of Helicobacter pylori, comprising an air sac (5) for storing samples and a kit (4) connected to the air sac (5) for detecting samples, characterized in that: The reagent kit (4) has two support plates (1) on its bottom surface, and a squeeze airbag (5) is provided between the two support plates (1) so that the sample in the airbag (5) is output to the squeeze component (3) in the reagent kit (4). The extrusion assembly (3) includes a hinge shaft (303) whose end is rotatably connected to the support plate (1). An extrusion plate (301) is fixedly provided on the hinge shaft (303). A driving member (302) is provided on the extrusion plate (301). The driving member (302) is used to drive the extrusion plate (301) to rotate around the hinge shaft (303) to cooperate with the bottom surface of the reagent kit (4) to extrude the airbag (5).

2. The pressure-stabilized air-blowing reagent kit for rapid detection of Helicobacter pylori as described in claim 1, characterized in that: The driving component (302) includes a snap-fit ​​bracket (3023) fixed on the reagent kit (4) and two connecting blocks (3021) on the extrusion plate (301). The snap-fit ​​bracket (3023) snaps into a mating post (3024), and the mating post (3024) and the connecting block (3021) are connected by a driving spring (3022).

3. The pressure-stabilized air-blowing reagent kit for rapid detection of Helicobacter pylori as described in claim 1, characterized in that: The driving component (302) includes two torsion springs (3025) sleeved on the hinge shaft (303). The torsion springs (3025) are located between the extrusion plate (301) and the support plate (1) to drive the extrusion plate (301) to flip.

4. The pressure-stabilized air-blowing reagent kit for rapid detection of Helicobacter pylori as described in claim 3, characterized in that: When the extrusion plate (301) is attached to the reagent kit (4), the outer edge of the extrusion plate (301) is positioned beyond the bottom surface of the reagent kit (4) away from the hinge shaft (303).

5. The pressure-stabilized air-blowing reagent kit for rapid detection of Helicobacter pylori as described in claim 1, characterized in that: Both of the support plates (1) have positioning grooves (2) which are opened and closed. The positioning grooves (2) include vertical grooves (202) and guide grooves (201) that are connected to the vertical grooves (202). The guide grooves (201) are arranged through one side of the support plate (1) away from the hinge shaft (303).

6. The pressure-stabilized air-blowing reagent kit for rapid detection of Helicobacter pylori as described in claim 1, characterized in that: The kit (4) includes a support plate (406) and a groove (403) on the top surface of the support plate (406). The groove (403) is connected to a connecting tube (401) on the support plate (406), and a detection plate (404) is provided in the groove (403). An observation hole (405) is provided at the center of the detection plate (404).

7. The pressure-stabilized air-blowing reagent kit for rapid detection of Helicobacter pylori as described in claim 6, characterized in that: A valve (402) is provided on the connecting pipe (401).

8. The pressure-stabilized air-blowing reagent kit for rapid detection of Helicobacter pylori as described in claim 1, characterized in that: The airbag (5) is provided with a transmission tube (501) and a one-way valve (502). The transmission tube (501) and the one-way valve (502) are symmetrically arranged along the length of the airbag (5), and the transmission tube (501) is used to communicate with the reagent kit (4) to output samples.

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