A pharmaceutical production system

Abstract

The utility model relates to the field of medicine production technology provides a medicine production system, including spray drying tower, still include first layer space, second layer space and third layer space along the height direction are sequentially arranged, the spray drying tower is located first layer space with second layer space, third layer space with first layer space all is equipped with the new air collection mouth, first layer space still is equipped with the exhaust room, between first layer space with second layer space and between second layer space with third layer space all are separated through the platform with the hole. The utility model discloses through the new air collection mouth of different floor space, the setting of exhaust room, again cooperate with the platform with the hole, can realize the air circulation of three floor space, reach the purpose of taking away room heat, solve the cooling problem in the industry on one hand, save the mechanical ventilation system of spray drying room on the other hand, thereby reduce equipment investment and operating cost.

Description

Technical Field

[0001] This utility model relates to the field of pharmaceutical manufacturing technology, specifically a pharmaceutical manufacturing system. Background Technology

[0002] Spray drying towers are commonly used as drying equipment, characterized by high temperatures, significant heat dissipation, and large size, thus occupying a considerable amount of space and area. In the chemical industry, they are often installed outdoors, while in pharmaceutical production, they must be installed indoors, resulting in extremely high room temperatures. The actual situation is as follows:

[0003] Commonly used spray drying equipment has a diameter of about 5m and requires a height of 15-18m, often arranged in a three-story building, with a single unit requiring an installation area of ​​about 600m2. The equipment has an air intake volume of about 10,000m3 / h and a temperature above 200℃, often using a combination of steam heating and electric heating. The high-temperature air instantly heats the atomized liquid, causing it to evaporate and the solute in the liquid to form a powder. After the air and powder cool and separate, they contain a certain amount of dust, which is removed before being discharged outdoors.

[0004] The heating unit of the equipment often has an independent duct to draw air from the outside. Due to the high temperature and large size of the equipment, even after insulation, it still generates significant heat to the room where it is located. Therefore, an independent ventilation system is needed to replace the room's heat with outdoor air. In this case, to protect the electrical control cabinet, a separate control room with comfort air conditioning is often provided, which actually increases the cabling between the control system and the equipment. In southern regions, where summer outdoor temperatures are high, although this method can remove heat from the equipment, the ambient temperature is still too high for areas where personnel frequently operate the equipment. Comfort air conditioning is then required for these areas to locally lower the ambient temperature. This approach requires a large-volume mechanical ventilation system, resulting in an unfriendly room environment and high energy consumption. Utility Model Content

[0005] The purpose of this invention is to provide a pharmaceutical production system that can at least solve some of the defects in the prior art.

[0006] To achieve the above objectives, the present invention provides the following technical solution: a pharmaceutical production system, including a spray drying tower, and further including a first layer space, a second layer space, and a third layer space arranged sequentially along the height direction. The spray drying tower is located in the first layer space and the second layer space. The third layer space and the first layer space are both provided with fresh air collection ports. The first layer space is also provided with an exhaust room. The first layer space and the second layer space, as well as the second layer space and the third layer space, are separated by a platform with holes.

[0007] Furthermore, the platform is a grid platform.

[0008] Furthermore, a filter assembly is also provided in the third layer space, and the fresh air collection port in the third layer space is connected to the spray drying tower through the filter assembly.

[0009] Furthermore, the fresh air intake in the third layer space is connected to the filter assembly via a heating assembly.

[0010] Furthermore, the heating assembly includes a steam heating unit and an electric heating unit connected in sequence. The fresh air intake in the third layer space is connected to the steam heating unit, and the electric heating unit is connected to the filter assembly.

[0011] Furthermore, a cyclone separator is also provided in the first layer of space, and the cyclone separator is connected to the fresh air collection port in the first layer of space and the spray drying tower respectively.

[0012] Furthermore, the cyclone separation assembly includes a primary cyclone separator and a secondary cyclone separator, with the bottom of the primary cyclone separator connected to the bottom of the secondary cyclone separator, and the fresh air intake in the first layer space connected to the bottom of the secondary cyclone separator.

[0013] Furthermore, a powder-collecting cyclone separator is connected to the bottom of the primary cyclone separator, and the powder-collecting cyclone separator is connected to the spray drying tower via an induced draft fan.

[0014] Furthermore, the secondary cyclone separator is connected to the dust collector via an exhaust fan.

[0015] Furthermore, the exhaust room is equipped with an exhaust fan, and the exhaust fan is connected to a jet air outlet.

[0016] Compared with the existing technology, the beneficial effects of this utility model are: by setting up fresh air collection ports and exhaust rooms in different floor spaces, and in conjunction with a platform with holes, air circulation can be achieved in a three-story space to remove room heat. On the one hand, it solves the cooling problem in the industry, and on the other hand, it eliminates the need for a mechanical ventilation system in the spray drying room, thereby reducing equipment investment and operating costs. Attached Figure Description

[0017] Figure 1 A schematic diagram of a pharmaceutical production system provided in an embodiment of this utility model;

[0018] In the attached diagram, the following labels are used: 1-Spray drying tower; 2-First layer space; 3-Second layer space; 4-Third layer space; 5-Fresh air intake; 6-Exhaust room; 7-Platform; 8-Filter assembly; 9-Steam heating unit; 10-Electric heating unit; 11-First-stage cyclone separator; 12-Second-stage cyclone separator; 13-Powder collecting cyclone separator; 14-Exhaust fan; 15-Exhaust fan; 16-Dust collector; 17-Exhaust fan; 18-Jet vent; 19-Louvre. Detailed Implementation

[0019] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the scope of protection of the present utility model.

[0020] Please see Figure 1 This utility model provides a pharmaceutical production system, including a spray drying tower 1 and a first-level space 2, a second-level space 3, and a third-level space 4 arranged sequentially along the height direction. The spray drying tower 1 is located in the first-level space 2 and the second-level space 3. Both the third-level space 4 and the first-level space 2 are equipped with fresh air intakes 5. The first-level space 2 also has an exhaust room 6. The first-level space 2 and the second-level space 3, as well as the second-level space 3 and the third-level space 4, are separated by a platform 7 with perforations. In this embodiment, by setting up fresh air intakes 5 and exhaust rooms 6 in different floor spaces, and in conjunction with the platform 7 with perforations, air circulation can be achieved across the three floors, achieving the purpose of removing heat from the rooms. This solves the cooling problem in the industry and eliminates the need for a mechanical ventilation system in the spray drying room, thereby reducing equipment investment and operating costs. If a mechanical ventilation system were installed, the area required for installing one spray drying tower 1 would be approximately 600m² across 1-3 floors. 2 Assuming a minimum air exchange rate of 3 times / hour, 10,000 m³ of space is required. 3 A ventilation system with a capacity of / h is provided. Specifically, a fresh air intake vent 5 is designed in the third-floor space 4, a fresh air intake vent 5 is designed in the first-floor space 2, and an exhaust room 6 is designed in the first-floor space 2. This allows air to circulate between the equipment installation spaces on different floors, achieving the purpose of removing room heat. A perforated platform 7 is used to facilitate airflow; preferably, the platform 7 is a grille platform.

[0021] Please see Figure 1The third-layer space 4 is further equipped with a filter assembly 8, and the fresh air intake 5 in the third-layer space 4 is connected to the spray drying tower 1 through the filter assembly 8. In this embodiment, the filter assembly 8 is used to purify outdoor air before it is introduced. The filtration method is an existing technology, such as activated carbon filtration, bag filtration, electrostatic filtration, etc., and this embodiment does not limit it.

[0022] Please see Figure 1 The fresh air intake 5 in the third-layer space 4 is connected to the filter assembly 8 via a heating assembly. Preferably, the heating assembly includes a steam heating unit 9 and an electric heating unit 10 connected in sequence. The fresh air intake 5 in the third-layer space 4 is connected to the steam heating unit 9, and the electric heating unit 10 is connected to the filter assembly 8. In this embodiment, the heating assembly is designed to heat the air when the outdoor temperature is low. The heating method can be steam heating, electric heating, or other existing heating methods; this embodiment does not limit this.

[0023] Please see Figure 1 The first layer space 2 is further equipped with a cyclone separator assembly, which is connected to the fresh air intake 5 in the first layer space 2 and the spray drying tower 1. Preferably, the cyclone separator assembly includes a primary cyclone separator 11 and a secondary cyclone separator 12. The bottom of the primary cyclone separator 11 is connected to the bottom of the secondary cyclone separator 12, and the fresh air intake 5 in the first layer space 2 is connected to the bottom of the secondary cyclone separator 12. In this embodiment, the cyclone separator is an existing device, and the material exiting the spray drying tower 1 enters the cyclone separator for separation.

[0024] Please see Figure 1 The bottom of the primary cyclone separator 11 is connected to a powder-collecting cyclone separator 13, which is connected to the spray drying tower 1 via an induced draft fan 14. In this embodiment, the exhaust air from the powder-collecting Class D clean area is introduced into the spray drying room to achieve the purpose of supplying comfortable air, without the need for a separate comfort air conditioning system, thus addressing the situation where outdoor air cannot be used to cool the room during the summer.

[0025] Please see Figure 1 The secondary cyclone separator 12 is connected to the dust collector 16 via the exhaust fan 15. In this embodiment, the dust is discharged outdoors after being removed by the dust collector 16.

[0026] Please see Figure 1 The exhaust room 6 is equipped with an exhaust fan, and the exhaust fan 17 is connected to a jet vent 18. In this embodiment, the exhaust fan 17 and the jet vent 18 are designed to increase the airflow rate.

[0027] Please see Figure 1 By installing louvers 19 on the walls of the first-floor space 2, it is possible to prevent quality accidents caused by room pressure.

[0028] Therefore, the above embodiments are as follows:

[0029] The spray drying unit occupies three floors of space. By using a steel platform, floor openings, or atriums, this space is transformed into a unified, well-ventilated area. Louvers are installed on the first-floor exterior wall, with the louver area calculated based on the spray drying tower's fresh air volume. The fresh air inlet for the spray drying tower is located at the top of the equipment (third floor), utilizing room ventilation. Fresh air enters from the first-floor exterior wall, passes through the main equipment areas on the first and second floors, and then enters the third-floor fresh air inlet. This method ensures a significant amount of fresh air replacement in the room during transitional seasons and winter (10,000 m³ per unit). 3 The spray drying process, operating at approximately 8000-10000 m³ / h, aims to cool the room. As required by regulations, the spray drying powder collection area is located in a Class D cleanroom, complemented by auxiliary cleanrooms for intermediate storage, mixing, equipment cleaning, and changing, forming a complete cleanroom. The cleanroom air conditioning system must have at least 20-30% fresh air to meet basic requirements for personnel work and dehumidification, resulting in 30% exhaust air. Under normal circumstances, this exhaust air, with a temperature of approximately 18-24℃, is discharged into the spray drying room (airflow approximately 8000-10000 m³ / h). 3 The system distributes air vents evenly to deliver comfortable air conditioning air without increasing investment and operating costs, thereby achieving the goal of cooling down in summer.

[0030] Note: The spray drying room does not require an additional mechanical ventilation system. When production is not in progress, the cleanroom air conditioning system continues to operate, and the clean air exhausted into the spray drying room will overflow to the outside through the exterior wall louvers, thus preventing pressure buildup and quality issues. The clean area is generally located on the first floor, therefore the air vents into the spray drying room are also located on the first floor. Since the air intake for spray drying is on the third floor, air convection is created, achieving simultaneous cooling on both the second and third floors.

[0031] Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the present invention, the scope of which is defined by the appended claims and their equivalents.

Claims

1. A drug product production system comprising a spray drying tower, characterized by: It also includes a first layer space, a second layer space, and a third layer space arranged sequentially along the height direction. The spray drying tower is located in the first layer space and the second layer space. The third layer space and the first layer space are both equipped with fresh air collection ports. The first layer space is also equipped with an exhaust room. The first layer space and the second layer space, as well as the second layer space and the third layer space, are separated by a platform with holes.

2. A pharmaceutical production system as claimed in claim 1, characterized in that The platform is a grid platform.

3. A pharmaceutical production system as claimed in claim 1, characterized in that The third layer space is also equipped with a filter assembly, and the fresh air collection port in the third layer space is connected to the spray drying tower through the filter assembly.

4. A pharmaceutical production system as claimed in claim 3, characterized in that: The fresh air intake in the third layer space is connected to the filter assembly via a heating assembly.

5. A pharmaceutical manufacturing system as described in claim 4, characterized in that: The heating assembly includes a steam heating unit and an electric heating unit connected in sequence. The fresh air intake in the third layer space is connected to the steam heating unit, and the electric heating unit is connected to the filter assembly.

6. A pharmaceutical manufacturing system as described in claim 1, characterized in that: The first layer of space is also equipped with a cyclone separator, which is connected to the fresh air collection port in the first layer of space and the spray drying tower.

7. A pharmaceutical manufacturing system as described in claim 6, characterized in that: The cyclone separation assembly includes a primary cyclone separator and a secondary cyclone separator. The bottom of the primary cyclone separator is connected to the bottom of the secondary cyclone separator, and the fresh air intake in the first layer space is connected to the bottom of the secondary cyclone separator.

8. A pharmaceutical manufacturing system as described in claim 7, characterized in that: The bottom of the primary cyclone separator is connected to a powder collecting cyclone separator, which is connected to the spray drying tower via an induced draft fan.

9. A pharmaceutical manufacturing system as described in claim 7, characterized in that: The secondary cyclone separator is connected to the dust collector via an exhaust fan.

10. A pharmaceutical manufacturing system as described in claim 1, characterized in that: The exhaust room is equipped with an exhaust fan, and the exhaust fan is connected to a jet air outlet.

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