A centrifugal device for cytosine preparation

By designing centrifuge devices for cleaning and separation components, the problem of impurity residue in existing technologies has been solved, achieving efficient solid-liquid separation and protective cover cleaning, thus improving the quality of cytosine products and the convenience of the device.

CN224405384UActive Publication Date: 2026-06-26XINXIANG RUINUO PHARM CO LTD

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
XINXIANG RUINUO PHARM CO LTD
Filing Date
2025-04-21
Publication Date
2026-06-26

AI Technical Summary

Technical Problem

Existing centrifuges used for cytosine preparation are prone to leaving impurities inside, leading to a decline in product quality and equipment performance.

Method used

A centrifuge device including a support column, a base, a drive unit, a rotating wheel, a cleaning component, a separation component, and a connecting component is designed. The cleaning component and the separation component achieve cleaning of the protective cover and solid-liquid separation. Corrosion-resistant and wear-resistant materials are used to ensure the durability and stability of the device.

Benefits of technology

It effectively cleans away impurities inside the protective cover during centrifugation, improves the quality of cytosine products, simplifies the pipeline connection process, and enhances the practicality and convenience of the device.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model relates to cytosine centrifugal technical field discloses a centrifugal device for cytosine preparation, including support, one end fixedly connected with base of support, the top of base is provided with protection cover, the top fixedly connected with drive arrangement of base, drive arrangement output fixedly connected with rotating wheel, the lateral wall of base is provided with cleaning component, the inside of rotating wheel is provided with separation component, the lateral wall of base is provided with connecting component, the cleaning component includes first connecting pipe, one end fixedly connected in the lateral wall of base of first connecting pipe, in the utility model, liquid is connected in one end of first connecting pipe, and liquid flows into the inside of protection cover, at the same time, the flow of liquid is controlled through the setting of solid outflow pipe and second valve, the problem that the internal impurity mixes in cytosine product in centrifugal process, causes the product quality to drop is solved, and the practicability of centrifugal device for cytosine preparation is improved.
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Description

Technical Field

[0001] This utility model relates to the field of cytosine centrifugation technology, and in particular to a centrifugation device for the preparation of cytosine. Background Technology

[0002] Cytosine is an important nitrogen-containing heterocyclic organic compound belonging to the pyrimidine class of bases. It is one of the four major bases that make up nucleic acids and plays a crucial role in the transmission of genetic information and protein synthesis in organisms. The preparation of cytosine requires the use of centrifugation equipment, mainly because centrifugation technology can efficiently separate and purify the target product and impurities in the reaction solution.

[0003] Existing centrifugal devices for cytosine preparation typically employ high-speed rotating drums or centrifuges to separate solid particles from liquids using centrifugal force. The drum usually contains filters or separation plates to retain solid particles, while the liquid is discharged through an outlet. Some high-end equipment is also equipped with automatic control systems that can adjust the rotation speed and separation time according to the material characteristics. Furthermore, existing devices are typically constructed of stainless steel to ensure corrosion resistance and structural strength.

[0004] However, impurities easily remain inside existing centrifuges, which can contaminate the cytosine product during subsequent centrifugation, leading to a decline in product quality. Traditional centrifuges lack effective cleaning functions, failing to thoroughly remove residual solid particles or liquids after each use. This not only increases the risk of product contamination but also degrades equipment performance and affects long-term stability. Therefore, a centrifuge device for cytosine preparation is proposed to address these issues. Utility Model Content

[0005] To overcome the above shortcomings, this utility model provides a centrifugation device for cytosine preparation, which aims to improve the problem in the prior art where internal impurities are mixed into the cytosine product during centrifugation, leading to a decline in product quality.

[0006] To achieve the above objectives, the present invention adopts the following technical solution:

[0007] A centrifuge device for preparing cytosine includes a support column, a base fixedly connected to one end of the support column, a protective cover provided on the top of the base, a drive device fixedly connected to the top of the base, a rotating wheel fixedly connected to the output end of the drive device, a cleaning component provided on the side wall of the base, a separation component provided inside the rotating wheel, and a connecting component provided on the side wall of the base.

[0008] The cleaning assembly includes a first connecting pipe, one end of which is fixedly connected to the side wall of the base. A liquid outflow tank is fixedly connected to the bottom of the base, and a solid outflow pipe is fixedly connected to the bottom of the base. A first valve is fixedly connected inside the solid outflow pipe, and a second valve is fixedly connected to one end of the liquid outflow tank.

[0009] As a further description of the above technical solution:

[0010] The separation component includes a helical blade, the outer wall of which is rotatably connected to the inside of a rotating wheel. The helical blade has a solid-liquid outflow hole inside, and the rotating wheel has a liquid outflow hole on its outer wall.

[0011] As a further description of the above technical solution:

[0012] The connecting component includes a connecting column, the bottom of which is fixedly connected to the top of the base, and a second connecting pipe is fixedly connected inside the connecting column. A fixing component is provided on the outer wall of the second connecting pipe.

[0013] As a further description of the above technical solution:

[0014] The fixing component includes a first clamping plate, the interior of which is disposed on the outer wall of the second connecting pipe, and a second clamping plate is disposed at the bottom of the first clamping plate, the interior of which is disposed on the outer wall of the second connecting pipe.

[0015] As a further description of the above technical solution:

[0016] The second clamping plate has a first connecting block fixedly connected to its side wall, and a rotating shaft is rotatably connected inside the first connecting block.

[0017] As a further description of the above technical solution:

[0018] A threaded rod is fixedly connected to the outer wall of the rotating shaft, a second connecting block is fixedly connected to the side wall of the first clamping plate, and an adjustment component is provided on the outer wall of the threaded rod.

[0019] As a further description of the above technical solution:

[0020] The adjusting assembly includes a nut, the nut being internally threaded onto the outer wall of a threaded rod.

[0021] As a further description of the above technical solution:

[0022] The nut contacts the second connecting block, and the outer wall of the threaded rod is rotatably connected to the side wall of the first clamping plate.

[0023] This utility model has the following beneficial effects:

[0024] 1. In this utility model, the liquid is connected to one end of the first connecting pipe and flows into the interior of the protective cover. At the same time, the flow of the liquid is controlled by setting the solid outflow pipe and the second valve, which achieves the effect of cleaning the impurities inside the protective cover. This solves the problem that the impurities inside will mix into the cytosine product during the centrifugation process, resulting in a decrease in product quality, and improves the practicality of the centrifugation device for cytosine preparation.

[0025] 2. In this utility model, by rotating the nut to make it rotate on the outer wall of the threaded rod, and with the bottom of the nut abutting against the top of the second connecting block, the effect of quick connection of the pipe is achieved. This solves the problem that it is impossible to quickly connect the pipe, and that a lot of time and effort are required to perform complex operations every time the pipe is installed or replaced. This improves the convenience of the centrifuge device for cytosine preparation. Attached Figure Description

[0026] Figure 1 This is a three-dimensional schematic diagram of a centrifuge apparatus for preparing cytosine according to the present invention;

[0027] Figure 2 This is a schematic diagram of the inner wall structure of the protective cover of a centrifuge device for preparing cytosine according to the present invention;

[0028] Figure 3 This is a schematic cross-sectional view of the rotating wheel of a centrifuge device for preparing cytosine proposed in this utility model;

[0029] Figure 4 This is a schematic diagram of the bottom structure of the base of a centrifuge device for preparing cytosine according to the present invention;

[0030] Figure 5 for Figure 3 Enlarged view of point A in the middle.

[0031] Legend:

[0032] 1. Base; 2. Support column; 3. Protective cover; 4. Drive device; 5. First connecting pipe; 6. Rotating wheel; 7. Spiral blade; 8. Liquid outlet hole; 9. Liquid outlet tank; 10. Solid outlet pipe; 11. First valve; 12. Second valve; 13. Connecting column; 14. Second connecting pipe; 15. First clamping plate; 16. Second clamping plate; 17. First connecting block; 18. Rotating shaft; 19. Threaded rod; 20. Second connecting block; 21. Nut; 22. Solid-liquid outlet hole. Detailed Implementation

[0033] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0034] Reference Figures 1-4 An embodiment of this utility model provides a centrifuge device for cytosine preparation, comprising a support column 2, one end of which is fixedly connected to a base 1. The base 1 is made of cast iron, which has high density and good shock absorption performance, and can effectively reduce the vibration during equipment operation. A protective cover 3 is provided on the top of the base 1. The protective cover 3 is made of transparent polycarbonate, which has high light transmittance and impact resistance, and facilitates observation of the internal operation. A drive device 4 is fixedly connected to the top of the base 1. A rotating wheel 6 is fixedly connected to the output end of the drive device 4. The rotating wheel 6 is made of high-strength aluminum alloy, which ensures its structural stability during high-speed rotation. A cleaning component is provided on the side wall of the base 1. A separation component is provided inside the rotating wheel 6. A connecting component is provided on the side wall of the base 1.

[0035] The cleaning assembly includes a first connecting pipe 5, which is made of corrosion-resistant PVC to ensure its durability when in contact with chemical liquids. One end of the first connecting pipe 5 is fixedly connected to the side wall of the base 1. A liquid outflow tank 9 is fixedly connected to the bottom of the base 1, and a solid outflow pipe 10 is fixedly connected to the bottom of the base 1. The solid outflow pipe 10 is made of stainless steel to ensure its long-term durability. A first valve 11 is fixedly connected inside the solid outflow pipe 10. The first valve 11 is made of corrosion-resistant copper alloy to ensure its sealing and durability. A second valve 12 is fixedly connected to one end of the liquid outflow tank 9. The second valve 12 is also made of copper alloy to ensure its long-term reliability. The separation assembly includes a spiral blade 7, which is made of high-strength stainless steel and has excellent wear resistance and corrosion resistance. The outer wall of the spiral blade 7 is rotatably connected to the inside of the rotating wheel 6. A solid-liquid outflow hole 22 is opened inside the spiral blade 7, and a liquid outflow hole 8 is opened on the outer wall of the rotating wheel 6.

[0036] Reference Figure 1 , Figure 3 and Figure 5The connecting assembly includes a connecting post 13, which is made of high-strength stainless steel to ensure structural stability. The bottom of the connecting post 13 is fixedly connected to the top of the base 1. A second connecting pipe 14 is fixedly connected inside the connecting post 13. The second connecting pipe 14 is made of corrosion-resistant PVC to ensure its durability in chemical environments. A fixing assembly is provided on the outer wall of the second connecting pipe 14. The fixing assembly includes a first clamping plate 15, which is made of high-strength engineering plastic to ensure structural stability and light weight. The interior of the first clamping plate 15 is located on the outer wall of the second connecting pipe 14. A second clamping plate 16 is provided at the bottom of the first clamping plate 15. The interior of the second clamping plate 16 is located on the outer wall of the second connecting pipe 14. A second clamping plate 16 is fixedly connected to the side wall of the second clamping plate 16. A connecting block 17 is made of aluminum alloy, combining lightweight and high strength. A rotating shaft 18 is rotatably connected inside the first connecting block 17. The rotating shaft 18 is made of high-hardness steel to ensure its long-term accuracy. A threaded rod 19 is fixedly connected to the outer wall of the rotating shaft 18. A second connecting block 20 is fixedly connected to the side wall of the first clamping plate 15. The second connecting block 20 is made of high-strength engineering plastic to ensure its structural stability. An adjustment component is provided on the outer wall of the threaded rod 19. The adjustment component includes a nut 21. The nut 21 is made of copper alloy to ensure its wear resistance and durability. The nut 21 is internally threaded and connected to the outer wall of the threaded rod 19. The nut 21 is in contact with the second connecting block 20. The outer wall of the threaded rod 19 is rotatably connected to the side wall of the first clamping plate 15.

[0037] Working principle: When connecting the pipes in the centrifuge for cytosine preparation, firstly, the threaded rod 19 is turned. The threaded rod 19 is forced to rotate the rotating shaft 18 inside the first connecting block 17, and the threaded rod 19 rotates in a circular motion around the central axis of the rotating shaft 18. When the threaded rod 19 rotates, its outer wall slides against the inner wall of the second connecting block 20. Next, the nut 21 is turned, causing it to rotate on the outer wall of the threaded rod 19, and the nut 21 moves linearly along the central axis of the threaded rod 19. When the nut 21 is rotated, the first clamping plate 15 is pressed against the outer wall of the second connecting pipe 14, and the first clamping plate 15 is pressed against the top of the second clamping plate 16, achieving the effect of quick pipe connection.

[0038] Then, when using the centrifuge for cytosine preparation, the threaded rod 19 is first connected to the solid-liquid material, which flows into the interior of the rotating wheel 6. Then, the output end of the drive device 4 drives the spiral blade 7 to rotate, and the spiral blade 7 moves in a circle along the central axis of the rotating wheel 6. Then, the solid-liquid material is thrown out into the interior of the spiral blade 7 through the solid-liquid outlet hole 22, so that it adheres to the interior of the rotating wheel 6. Next, during centrifugation, the liquid is first thrown out from the liquid outlet hole 8 and flows out through the liquid outlet tank 9. Then, when the rotating wheel 6 rotates, the solid will be discharged through the solid outlet pipe 10, thus achieving the effect of cytosine separation.

[0039] Then, when cleaning the protective cover 3, the liquid is first connected to one end of the first connecting pipe 5, and then the liquid flows into the inside of the protective cover 3. Then, the output end of the drive device 4 drives the rotating wheel 6 to rotate inside the protective cover 3. Then, the design of the first valve 11 controls the liquid outflow from the solid outflow pipe 10, thereby achieving the effect of cleaning the impurities inside the protective cover 3.

[0040] Finally, it should be noted that the above description is only a preferred embodiment of the present utility model and is not intended to limit the present utility model. Although the present utility model has been described in detail with reference to the foregoing embodiments, those skilled in the art can still modify the technical solutions described in the foregoing embodiments or make equivalent substitutions for some of the technical features. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present utility model should be included within the protection scope of the present utility model.

Claims

1. A centrifuge apparatus for the preparation of cytosine, comprising a support column (2), characterized in that: One end of the support column (2) is fixedly connected to a base (1), a protective cover (3) is provided on the top of the base (1), a driving device (4) is fixedly connected to the top of the base (1), a rotating wheel (6) is fixedly connected to the output end of the driving device (4), a cleaning component is provided on the side wall of the base (1), a separation component is provided inside the rotating wheel (6), and a connecting component is provided on the side wall of the base (1). The cleaning assembly includes a first connecting pipe (5), one end of which is fixedly connected to the side wall of the base (1). A liquid outflow tank (9) is fixedly connected to the bottom of the base (1), and a solid outflow pipe (10) is fixedly connected to the bottom of the base (1). A first valve (11) is fixedly connected inside the solid outflow pipe (10), and a second valve (12) is fixedly connected to one end of the liquid outflow tank (9).

2. The centrifuge apparatus for preparing cytosine according to claim 1, characterized in that: The separation component includes a spiral blade (7), the outer wall of which is rotatably connected to the inside of a rotating wheel (6). The spiral blade (7) has a solid-liquid outflow hole (22) inside, and the rotating wheel (6) has a liquid outflow hole (8) on its outer wall.

3. The centrifuge apparatus for preparing cytosine according to claim 2, characterized in that: The connecting assembly includes a connecting column (13), the bottom of which is fixedly connected to the top of the base (1), and a second connecting pipe (14) is fixedly connected inside the connecting column (13), with a fixing component provided on the outer wall of the second connecting pipe (14).

4. The centrifuge apparatus for preparing cytosine according to claim 3, characterized in that: The fixing component includes a first clamping plate (15), the interior of which is disposed on the outer wall of the second connecting pipe (14), and a second clamping plate (16) is disposed at the bottom of the first clamping plate (15), the interior of which is disposed on the outer wall of the second connecting pipe (14).

5. A centrifuge apparatus for preparing cytosine according to claim 4, characterized in that: The second clamping plate (16) has a first connecting block (17) fixedly connected to its side wall, and a rotating shaft (18) is rotatably connected inside the first connecting block (17).

6. A centrifuge apparatus for preparing cytosine according to claim 5, characterized in that: A threaded rod (19) is fixedly connected to the outer wall of the rotating shaft (18), and a second connecting block (20) is fixedly connected to the side wall of the first clamping plate (15). An adjustment component is provided on the outer wall of the threaded rod (19).

7. A centrifuge apparatus for preparing cytosine according to claim 6, characterized in that: The adjusting assembly includes a nut (21), which is internally threaded to the outer wall of the threaded rod (19).

8. A centrifuge apparatus for preparing cytosine according to claim 7, characterized in that: The nut (21) is in contact with the second connecting block (20), and the outer wall of the threaded rod (19) is rotatably connected to the side wall of the first clamping plate (15).