A purging device for a liquid preparation system

Abstract

The application relates to a purging device for a liquid preparation system and relates to the technical field of medicine liquid preparation. In order to solve the problem that a traditional purging device cannot completely purge, the purging device comprises a conveying pipeline, the inlet end of the conveying pipeline is provided with a compressed air supply source, the outlet end of the compressed air supply source is sequentially and serially provided with a pressure reducing valve and an electric heater along the conveying pipeline, a plurality of heating modules are arranged in the electric heater, the plurality of heating modules are vertically stacked along the height direction of the electric heater, a heating channel is formed in the electric heater from bottom to top, and a temperature gradient from low to high is formed when the compressed air flows through the heating channel. The application has the effects of effectively stripping the residual moisture on the surface of the system, improving the removal rate of the residual moisture and solving the microbial pollution risk caused by incomplete purging.

Description

Technical Field

[0001] This application relates to the field of pharmaceutical solution preparation technology, and in particular to a purging device for a solution preparation system. Background Technology

[0002] In pharmaceutical dispensing systems, cleaning and sterilization are core steps in ensuring drug production quality. Dispensing systems typically consist of complex components such as tanks, pipes, and valves, and the cleanliness of their surfaces directly affects the sterility of the drugs. According to the Good Manufacturing Practice (GMP) requirements for pharmaceuticals, after cleaning or sterilization, the dispensing system must be purged with compressed air to remove residual moisture and prevent microbial growth.

[0003] However, when traditional purging devices use compressed air for purging, trace amounts of water droplets or condensation may appear on the system surface during cleaning and sterilization. Furthermore, the purging process using compressed air is easily affected by pressure, flow rate, and temperature, which can lead to incomplete purging. The residual moisture not only provides a breeding environment for microorganisms but may also contaminate subsequent drug solutions, seriously threatening the quality and safety of the drugs. Therefore, improvements are needed. Utility Model Content

[0004] To address the problem of incomplete purging in traditional purging devices, this application provides a purging device for a liquid preparation system.

[0005] The purging device for a liquid preparation system provided in this application adopts the following technical solution:

[0006] A purging device for a liquid preparation system includes a delivery pipeline. A compressed air supply source is provided at the inlet end of the delivery pipeline. A pressure reducing valve and an electric heater are connected in series along the delivery pipeline at the outlet end of the compressed air supply source. Multiple heating modules are provided inside the electric heater. The multiple heating modules are stacked vertically along the height direction of the electric heater. A heating channel is formed inside the electric heater from bottom to top. When the compressed air flows through the heating channel, a temperature gradient from low to high is formed.

[0007] Traditional purging devices, when using compressed air for purging, produce trace amounts of water droplets or condensation on the system surface during cleaning and sterilization. Furthermore, the purging process using compressed air is easily affected by pressure, flow rate, and temperature, leading to incomplete purging. Residual moisture not only provides a breeding environment for microorganisms but may also contaminate subsequent drug solutions, seriously threatening drug quality and safety. By adopting the above-mentioned technical solution, including a delivery pipeline, a compressed air supply source is installed at the inlet end of the delivery pipeline, and a pressure reducing valve and an electric heater are sequentially connected in series on the delivery pipeline. Multiple heating modules are vertically stacked inside the electric heater to form a heating channel.

[0008] When purging the liquid preparation system, the end of the delivery pipeline is connected to the corresponding liquid preparation system pipeline. After the compressed air supply source is started, the original compressed air enters the inlet end of the delivery pipeline. The pressure reducing valve stabilizes the air pressure within a suitable working range to prevent high-pressure airflow from impacting the system components. The depressurized air enters the electric heater and flows from bottom to top along the heating channel formed by the vertically stacked heating modules, creating a temperature gradient from low to high. This causes the compressed air to gradually heat up and fully absorb heat energy. The dry hot air enters the liquid preparation system pipeline for purging, effectively driving the movement of residual moisture and accelerating its vaporization until the removal of residual moisture is completed.

[0009] By incorporating delivery pipelines, pressure-reducing valves, electric heaters, and heating modules, the pressure-reducing valves precisely regulate air pressure, preventing high-pressure impacts on the precision components of the liquid preparation system and providing a stable flow field for uniform heating. Meanwhile, the gradient heating module, through a layered temperature control strategy, gradually heats the compressed air and fully absorbs heat energy, significantly increasing the enthalpy value, effectively removing residual moisture from the system surface, improving the residual moisture removal rate, and resolving the risk of microbial contamination caused by incomplete purging, thus ensuring the quality and safety of drug production.

[0010] Optionally, the air inlet of the electric heater is located at the bottom, the air outlet of the electric heater is located at the top, and the power configuration of the multiple sets of heating modules increases progressively from bottom to top along the height direction of the electric heater.

[0011] By adopting the above technical solution, the air inlet of the electric heater is located at the bottom, the air outlet of the electric heater is located at the top, and the power configuration of multiple heating modules increases gradually from bottom to top along the height direction of the electric heater. Through the air inlet and outlet paths of the electric heater and the setting of the heating modules, a gradient heating is formed, ensuring the uniformity of the outlet air temperature and improving the thermal energy utilization rate.

[0012] Optionally, the outer surface of the electric heater is provided with a composite insulation layer, which includes a heat insulation felt and a protective sleeve, arranged sequentially from the inside to the outside.

[0013] By adopting the above technical solution, a composite insulation layer is wrapped around the surface of the electric heater. The composite insulation layer includes a heat insulation felt and a protective sleeve. Through the setting of the composite insulation layer, the heat insulation felt can significantly block the heat radiation generated by the operation of the electric heater, reduce the heat loss to the environment, and ensure the heating efficiency of compressed air. The outer protective sleeve can resist mechanical collisions in the production site. The composite structure keeps the surface temperature of the equipment within a safe range and effectively eliminates the risk of burns to operators.

[0014] Optionally, the delivery pipeline is equipped with a compressed air pressure display unit for real-time monitoring of the air pressure after depressurization, and the compressed air pressure display unit is located at the outlet end of the pressure reducing valve.

[0015] By adopting the above technical solution, the compressed air pressure display unit is installed at the outlet end of the pressure reducing valve. By setting up the compressed air pressure display unit, the operator can intuitively grasp the stable state of the compressed air by monitoring the air pressure value after pressure reduction in real time. This ensures that the air pressure entering the electric heater is always within the precise range required by the process, avoiding uneven heating or damage to system components caused by airflow impact due to pressure fluctuations, and improving the controllability and stability of the purging process.

[0016] Optionally, the delivery pipeline is also equipped with a compressed air temperature display unit for real-time monitoring of air temperature, and the compressed air temperature display unit is located at the outlet end of the electric heater.

[0017] By adopting the above technical solution, the compressed air temperature display unit is installed at the outlet end of the electric heater. With the setting of the compressed air temperature display unit, the temperature of the airflow after heating can be monitored in real time and accurately, so that the operator can intuitively grasp the parameters of the dry hot air. This ensures that the temperature of the hot air entering the liquid distribution system strictly meets the process requirements, avoids incomplete vaporization of residual moisture due to insufficient temperature, or aging of pipeline materials due to excessive temperature, and improves the temperature uniformity of the purging process.

[0018] Optionally, the output end of the conveying pipeline is provided with a quick-release flange, and the sealing surface of the quick-release flange is provided with an O-ring.

[0019] By adopting the above technical solution, the quick-release flange is installed at the output end of the conveying pipeline, and the O-ring is embedded in the sealing surface of the quick-release flange. Through the setting of quick-release flange and O-ring, the quick-release flange shortens the docking time between the pipeline and the liquid distribution system. At the same time, the O-ring can automatically compensate for installation errors, forming a double sealing barrier to ensure zero leakage of high temperature and high pressure airflow during purging, and improve the convenience of equipment maintenance and the reliability of long-term operation.

[0020] Optionally, the quick-release flange is provided with an airflow guide ring at the interface, and the inner wall of the airflow guide ring is provided with a spiral guide groove for eliminating the dead angle of vortex at the end of the pipe.

[0021] By adopting the above technical solution, the airflow guide ring is installed at the interface of the quick-release flange, and the spiral guide groove is opened on the inner wall of the airflow guide ring. Through the setting of the airflow guide ring and the spiral guide groove, the spiral structure forms a uniform spiral flow field by forcing the airflow to rotate, effectively eliminating the vortex dead angle that is easy to be generated at the end of the traditional straight pipe, making the airflow energy distribution more balanced and improving the efficiency of removing residual moisture.

[0022] Optionally, a control valve is installed on the delivery pipeline between the compressed air supply source outlet and the pressure reducing valve.

[0023] By adopting the above technical solution, the control valve is installed between the compressed air supply outlet and the pressure reducing valve. By setting the control valve as the airflow interruption control hub, the purging operation can be started and stopped quickly and controlled in stages, improving the operational flexibility and safety of the purging process.

[0024] In summary, this application includes at least one of the following beneficial technical effects:

[0025] 1. By setting up delivery pipelines, pressure reducing valves, electric heaters, and heating modules, the pressure reducing valves precisely regulate air pressure, avoiding high pressure impact on the precision components of the liquid preparation system and providing a stable flow field for uniform heating. At the same time, the gradient heating module, through a layered temperature control strategy, gradually heats the compressed air and fully absorbs heat energy, significantly increasing the enthalpy value, effectively removing residual moisture from the system surface, improving the residual moisture removal rate, solving the risk of microbial contamination caused by incomplete purging, and ensuring the quality and safety of drug production.

[0026] 2. Through the setting of the composite insulation layer, the heat insulation felt can significantly block the heat radiation generated by the operation of the electric heater, reduce the heat loss to the environment, and ensure the heating efficiency of compressed air. The outer protective sleeve can resist mechanical collisions on the production site. The composite structure keeps the surface temperature of the equipment within a safe range and effectively eliminates the risk of burns to operators.

[0027] 3. By monitoring the airflow pressure value after decompression in real time, operators can intuitively grasp the stable state of compressed air, ensuring that the air pressure entering the electric heater is always within the precise range required by the process, avoiding uneven heating or damage to system components caused by airflow impact due to pressure fluctuations, and improving the controllability and stability of the purging process. Attached Figure Description

[0028] Figure 1 This is a schematic diagram of the structure of a purging device for a liquid preparation system in an embodiment of this application.

[0029] Figure 2 This is a cross-sectional view of a purging device for a liquid preparation system according to an embodiment of this application.

[0030] Figure 3 yes Figure 2 Enlarged view of part A in the image.

[0031] Explanation of reference numerals in the attached drawings: 1. Delivery pipeline; 2. Compressed air supply source; 3. Pressure reducing valve; 4. Electric heater; 5. Heating module; 6. Composite insulation layer; 61. Insulation felt; 62. Protective sleeve; 7. Compressed air pressure display unit; 8. Compressed air temperature display unit; 9. Quick-release flange; 10. O-ring seal; 11. Airflow guide ring; 12. Spiral guide groove; 13. Control valve. Detailed Implementation

[0032] The following is in conjunction with the appendix Figure 1-3 This application will be described in further detail.

[0033] This application discloses a purging device for a liquid preparation system. (Refer to...) Figure 1 The purging device for the liquid preparation system includes a delivery pipe 1. A compressed air supply source 2 is installed at the inlet end of the delivery pipe 1. In this embodiment, the compressed air supply source 2 can deliver compressed air through its own pump body. The output end of the delivery pipe 1 can be connected to the corresponding liquid preparation system pipeline.

[0034] Reference Figure 1 The compressed air supply source 2 has a control valve 13, a pressure reducing valve 3 and an electric heater 4 installed in series along the conveying pipeline 1 at the outlet end. As the air flow control hub, it can realize the rapid start and stop and segmented control of the purging operation, and improve the operational flexibility and safety of the purging process.

[0035] Reference Figure 1 The pressure reducing valve 3 stabilizes the air pressure within a suitable working range. A compressed air pressure display unit 7 is installed on the delivery pipeline 1. The compressed air pressure display unit 7 is located at the outlet end of the pressure reducing valve 3. In this embodiment, the compressed air pressure display unit 7 can be a digital pressure gauge that can display the real-time pressure value. By monitoring the airflow pressure value after pressure reduction in real time, the operator can intuitively grasp the stable state of the compressed air, ensuring that the air pressure entering the electric heater 4 is always within the precise range required by the process, avoiding uneven heating or airflow impact damage to system components due to pressure fluctuations, and improving the controllability and stability of the purging process.

[0036] Reference Figure 1 and Figure 2 In this embodiment, the air inlet of the electric heater 4 is located at the bottom, and the air outlet of the electric heater 4 is located at the top, so that the compressed air adjusted by the pressure reducing valve enters from the bottom of the electric heater 4 and exits from the top. Multiple heating modules 5 are installed inside the electric heater 4. The multiple heating modules 5 are stacked vertically along the height direction of the electric heater 4, so that a heating channel from bottom to top is formed inside the electric heater 4. When the compressed air flows through the heating channel, a temperature gradient from low to high is formed. At the same time, the power configuration of the multiple heating modules 5 increases step by step from bottom to top along the height direction of the electric heater 4. The heating module can be an electric heating tube, a ceramic heating plate or other heating body.

[0037] Reference Figure 1 and Figure 2Meanwhile, the electric heater 4 is covered with a composite insulation layer 6, which includes a heat insulation felt 61 and a protective sleeve 62. The heat insulation felt 61 and the protective sleeve 62 are arranged from the inside to the outside. The heat insulation felt 61 can significantly block the heat radiation generated by the operation of the electric heater 4, reduce the heat loss to the environment, and ensure the heating efficiency of compressed air. The outer protective sleeve 62 can resist mechanical collisions in the production site. The composite structure keeps the surface temperature of the equipment within a safe range and effectively eliminates the risk of burns to operators.

[0038] Reference Figure 1 The delivery pipeline 1 is also equipped with a compressed air temperature display unit 8, which is located at the outlet end of the electric heater 4. In this embodiment, the compressed air temperature display unit 8 can be a digital temperature instrument to display the real-time temperature value, which can accurately monitor the temperature of the airflow after heating in real time, so that the operator can intuitively grasp the parameters of the dry hot air. This ensures that the temperature of the hot air entering the liquid distribution system strictly meets the process requirements, avoids incomplete vaporization of residual moisture due to insufficient temperature, or aging of pipeline materials due to excessive temperature, and improves the temperature uniformity of the purging process.

[0039] Reference Figure 3 The output end of the conveying pipeline 1 is equipped with a quick-release flange 9, and the sealing surface of the quick-release flange 9 is fitted with an O-ring seal 10. In this embodiment, the compressed air supply source 2, the electric heater 4, and the conveying pipeline 1 can adopt an integrated modular design. They can be configured as a movable integrated structure (for flexible deployment between different liquid preparation stations) or directly integrated into the main frame of the liquid preparation system through a fixed installation structure (to achieve long-term stable operation). The quick-release flange 9 shortens the docking time between the pipeline and the liquid preparation system. At the same time, the O-ring seal 10 can automatically compensate for installation errors, forming a double sealing barrier to ensure zero leakage of high-temperature and high-pressure airflow during the purging process, thereby improving the convenience of equipment maintenance and the reliability of long-term operation.

[0040] Reference Figure 3 Meanwhile, an airflow guide ring 11 is installed at the interface of the quick-release flange 9. The inner wall of the airflow guide ring 11 is provided with a spiral guide groove 12 to eliminate the dead angle of vortex at the end of the pipe. The spiral structure forms a uniform spiral flow field by forcing the airflow to rotate, which effectively eliminates the dead angle of vortex that is easy to be generated at the end of traditional straight pipes, making the airflow energy distribution more balanced and improving the efficiency of removing residual moisture.

[0041] The implementation principle of a purging device for a liquid preparation system in this application embodiment is as follows: When purging the liquid preparation system, the end of the delivery pipe 1 is connected to the corresponding liquid preparation system pipe. After the control valve 13 is opened and the compressed air supply source 2 is started, the original compressed air enters the inlet end of the delivery pipe 1. The pressure reducing valve 3 stabilizes the air pressure within a suitable working range to avoid high-pressure airflow impacting the system components. The compressed air pressure display unit 7 monitors the pressure after pressure reduction in real time. The air after pressure reduction enters the electric heater 4 and flows from bottom to top along the heating channel formed by the vertically stacked heating modules 5, forming a temperature gradient from low to high, so that the compressed air gradually heats up and fully absorbs heat energy. The compressed air temperature display unit 8 monitors the air temperature in real time. The dry hot air enters the liquid preparation system pipe for purging, effectively driving the movement of residual moisture and accelerating its vaporization until the removal of residual moisture is completed.

[0042] By setting up the delivery pipeline 1, pressure reducing valve 3, electric heater 4, and heating module 5, the pressure reducing valve 3 precisely regulates the air pressure, avoiding high pressure impact on the precision components of the liquid preparation system, and provides a stable flow field for uniform heating. At the same time, the gradient heating module 5, through a layered temperature control strategy, gradually heats the compressed air and fully absorbs heat energy, significantly increasing the enthalpy value, effectively removing residual moisture from the system surface, improving the residual moisture removal rate, solving the risk of microbial contamination caused by incomplete purging, and ensuring the quality and safety of drug production.

[0043] The above are all preferred embodiments of this application, and are not intended to limit the scope of protection of this application. Therefore, all equivalent changes made in accordance with the structure, shape and principle of this application should be covered within the scope of protection of this application.

Claims

1. A purging device for a liquid preparation system, characterized by: The device includes a conveying pipeline, with a compressed air supply source at the inlet end of the conveying pipeline. A pressure reducing valve and an electric heater are connected in series along the outlet end of the compressed air supply source. The electric heater contains multiple heating modules, which are stacked vertically along the height of the electric heater. A heating channel is formed inside the electric heater from bottom to top, and the compressed air forms a temperature gradient from low to high when it flows through the heating channel. 2.The purging device for a liquid preparation system according to claim 1, characterized in that: The air inlet of the electric heater is located at the bottom, and the air outlet of the electric heater is located at the top. The power configuration of the multiple heating modules increases progressively from bottom to top along the height direction of the electric heater.

3. The purging device for a liquid preparation system according to claim 1, characterized in that: The outer surface of the electric heater is provided with a composite insulation layer, which includes a heat insulation felt and a protective sleeve, arranged sequentially from the inside to the outside.

4. The purging device for a liquid preparation system according to claim 1, characterized in that: The delivery pipeline is equipped with a compressed air pressure display unit for real-time monitoring of the air pressure after depressurization. The compressed air pressure display unit is located at the outlet end of the pressure reducing valve.

5. A purging device for a liquid preparation system according to claim 1, characterized in that: The delivery pipeline is also equipped with a compressed air temperature display unit for real-time monitoring of air temperature, and the compressed air temperature display unit is located at the outlet end of the electric heater.

6. The purging device for a liquid preparation system according to claim 1, characterized in that: The output end of the conveying pipeline is equipped with a quick-release flange, and the sealing surface of the quick-release flange is equipped with an O-ring.

7. A purging device for a liquid preparation system according to claim 6, characterized in that: The quick-release flange is provided with an airflow guide ring at its interface, and the inner wall of the airflow guide ring is provided with a spiral guide groove for eliminating the dead angle of vortex at the end of the pipe.

8. A purging device for a liquid preparation system according to claim 1, characterized in that: A control valve is installed on the delivery pipeline between the outlet end of the compressed air supply source and the pressure reducing valve.

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