A portable electroanalytical device

Abstract

This application discloses a portable electroanalytical device, relating to the field of chemical detection technology. The device includes a microfluidic chip, a detection circuit, a microcontroller module, and a display module. The electrodes of the microfluidic chip are connected to the microcontroller module via the detection circuit, and the display module is connected to the microcontroller module. Specifically: the microfluidic chip is used to hold the liquid to be analyzed; the detection circuit is used to convert data from the liquid to be analyzed and acquire detection data; the microcontroller module is used to carry electrochemical detection software to perform electroanalytical analysis on the detection data; and the display module is used to enable interaction between the user and the microcontroller module and to display the results. This application enables the miniaturization of the electroanalytical device.

Description

Technical Field

[0001] This application relates to the field of chemical detection technology, and in particular to a portable electroanalytical device. Background Technology

[0002] Electrochemical detection technology has a long history, with electrolytic analysis and coulometric titration appearing as early as the 18th century. Since the 20th century, with the continuous improvement of electrochemical theory and breakthroughs in related technologies, electrochemical detection has gradually become an important analytical tool. Its development is closely related to multiple disciplines such as life sciences, environmental sciences, and energy sciences.

[0003] In recent years, with the increasing demand for high-precision and high-efficiency detection technologies in fields such as new energy, new materials, environmental protection, and biomedicine, electrochemical detection technology has gradually become an important analytical tool due to its unique advantages, showing broad application prospects in environmental monitoring, food safety, medical health, and industrial fields. With the development of the Internet of Things, big data, and artificial intelligence technologies, electrochemical detection technology is developing towards intelligence, miniaturization, and high precision.

[0004] The commercial electrochemical workstation currently in use is fully functional, has guaranteed measurement accuracy, and is a complete system, but its large size makes it unsuitable for applications in confined spaces. Utility Model Content

[0005] The purpose of this application is to provide a portable electrical analysis device that enables miniaturization of the electrical analysis device.

[0006] To achieve the above objectives, this application provides the following solution:

[0007] This application provides a portable electrical analysis device, comprising:

[0008] The system comprises a microfluidic chip, a detection circuit, a microcontroller module, and a display module; the electrodes of the microfluidic chip are connected to the microcontroller module via the detection circuit, and the display module is connected to the microcontroller module, wherein:

[0009] The microfluidic chip is used to hold the liquid to be analyzed;

[0010] The detection circuit is used to convert data from the liquid to be analyzed to obtain detection data;

[0011] The controller module is used to carry electrochemical detection software to perform electrochemical analysis on the detection data;

[0012] The display module is used to enable interaction between the user and the microcontroller module and to display the results.

[0013] Optionally, the microcontroller module includes a first microcontroller and a second microcontroller; the electrodes of the microfluidic chip are connected to the first microcontroller through the detection circuit, and the first microcontroller is connected to the second microcontroller. Two microcontrollers are connected;

[0014] The first microcontroller is used to implement data transmission;

[0015] The second microcontroller is used to perform data processing and interact with the display module.

[0016] Optionally, the detection circuit includes a first inverting operational amplifier module, a second non-inverting operational amplifier module, a third inverting operational amplifier module, a fourth non-inverting operational amplifier module, a fifth inverting operational amplifier module, a sixth inverting operational amplifier module, a seventh inverting operational amplifier module, an eighth non-inverting operational amplifier module, a digital-to-analog converter module, an analog-to-digital converter module, and a switching module; wherein:

[0017] The first microcontroller is connected to the input terminal of the second non-inverting operational amplifier module through the digital-to-analog converter module, the output terminal of the second non-inverting operational amplifier module is connected to the first input terminal of the third inverting operational amplifier module, and the first input terminal of the third inverting operational amplifier module is also connected to the first microcontroller module through the analog-to-digital converter module;

[0018] The output terminal of the third inverting operational amplifier module is connected to the first input terminal of the fifth inverting operational amplifier module; the second input terminal of the fifth inverting operational amplifier module is connected to the output terminal of the fourth non-inverting operational amplifier module; the output terminal of the fifth inverting operational amplifier module is connected to the counter electrode of the microfluidic chip through the switching module; the switching module implements switching control through the first microcontroller.

[0019] The positive input terminal of the fourth in-phase operational amplifier module is connected to the reference electrode of the microfluidic chip;

[0020] The second input terminal of the third inverting operational amplifier module is connected to the output terminal of the first inverting operational amplifier module, and the input terminal of the first inverting operational amplifier module is connected to the first microcontroller; the output terminal of the first inverting operational amplifier module is also connected to the first input terminal of the seventh inverting operational amplifier module.

[0021] The second input terminal of the seventh inverting operational amplifier module is connected to the output terminal of the sixth inverting operational amplifier module, and the input terminal of the sixth inverting operational amplifier module is connected to the working electrode of the microfluidic chip.

[0022] The output of the seventh inverting operational amplifier module is connected to the first microcontroller through the analog-to-digital converter module.

[0023] Optionally, the third inverting operational amplifier module includes a third resistor, a fourth resistor, a fifth resistor, a sixth resistor, and a third operational amplifier; wherein:

[0024] The first input terminal of the third inverting operational amplifier module is connected to one end of the fourth resistor, one end of the fourth resistor is connected to one end of the fifth resistor, and the other end of the fourth resistor is connected to the other end of the fifth resistor; the other end of the fourth resistor is connected to the negative input terminal of the third operational amplifier, the positive input terminal of the third operational amplifier is connected to reference ground, and the negative input terminal of the third operational amplifier is connected to the output terminal of the third operational amplifier through the sixth resistor.

[0025] The negative input terminal of the third operational amplifier is connected to one end of the third resistor, and the other end of the third resistor serves as the second input terminal of the third inverting operational amplifier module.

[0026] The output terminal of the third operational amplifier is used as the output terminal of the third operational amplifier.

[0027] Optionally, the fifth inverting operational amplifier module includes a seventh resistor, an eighth resistor, and a fifth operational amplifier; wherein

[0028] One end of the eighth resistor serves as the first input terminal of the fifth inverting operational amplifier module, the other end of the eighth resistor is connected to the negative input terminal of the fifth operational amplifier, the positive input terminal of the fifth operational amplifier is connected to reference ground, and the output terminal of the fifth operational amplifier serves as the output terminal of the fifth inverting operational amplifier module.

[0029] The negative input terminal of the fifth operational amplifier is also connected to one end of the seventh resistor, and the other end of the seventh resistor serves as the second input terminal of the fifth inverting operational amplifier module.

[0030] Optionally, the seventh inverting operational amplifier module includes a ninth resistor, a tenth resistor, an eleventh resistor, a twelfth resistor, a thirteenth resistor, and a seventh operational amplifier; wherein:

[0031] The first input terminal of the seventh inverting operational amplifier module is connected to the negative input terminal of the seventh operational amplifier through the ninth resistor. The negative input terminal of the seventh operational amplifier is also connected to the second input terminal of the seventh inverting operational amplifier module through the tenth resistor. The negative input terminal of the seventh operational amplifier is also connected to the second input terminal of the seventh inverting operational amplifier module through the eleventh resistor.

[0032] The negative input terminal of the seventh operational amplifier is also connected to the output terminal of the seventh operational amplifier through the twelfth resistor; the negative input terminal of the seventh operational amplifier is also connected to the output terminal of the seventh operational amplifier through the thirteenth resistor.

[0033] The positive input terminal of the seventh operational amplifier is connected to the reference ground; the output terminal of the seventh operational amplifier is the output terminal of the seventh inverting operational amplifier module.

[0034] Optionally, the portable electrical analyzer further includes a battery module for powering the detection circuit and the microcontroller module.

[0035] Optionally, the portable electrical analyzer further includes a voltage regulator module, and the battery module is connected to the detection circuit through the voltage regulator module.

[0036] Optionally, the portable electrical analyzer further includes a housing, in which the battery module, the detection circuit, and the microcontroller module are all fixed, and the microfluidic chip is fixed on the outer wall of the housing.

[0037] Optionally, the portable electrical analyzer further includes a cooling fan, which is fixed in the housing and powered by the battery module. The cooling fan is used to dissipate heat from the detection circuit and the microcontroller module.

[0038] According to the specific embodiments provided in this application, the following technical effects are disclosed:

[0039] This application provides a portable electroanalytical device that uses a microfluidic chip to carry the liquid to be analyzed, a detection circuit to convert signals, a microcontroller to perform electrochemical analysis on the liquid, and a display module to interact with the microcontroller and display the structure. This application reduces the size of the electrochemical detection system and provides a new solution for applications in small spaces. Attached Figure Description

[0040] To more clearly illustrate the technical solutions in the embodiments of this application or the prior art, the drawings used in the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments of this application. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0041] Figure 1 A schematic diagram of a portable electrical analysis device provided in an embodiment of this application;

[0042] Figure 2 A schematic diagram of a detection circuit provided in an embodiment of this application;

[0043] Figure 3 A schematic diagram of the result of Embodiment 1 provided in this application;

[0044] Figure 4 A schematic diagram of the result of Embodiment 2 provided in this application;

[0045] Figure 5 This is a schematic diagram showing the result of Embodiment 3, which is an embodiment of this application.

[0046] Explanation of reference numerals in the attached figures:

[0047] 110 - Microfluidic chip;

[0048] 120 - Detection circuit;

[0049] 131 - First microcontroller; 132 - Second microcontroller;

[0050] 140 - Battery Module;

[0051] 150 - Display Module;

[0052] 160- Cooling fan;

[0053] 170 - Outer shell;

[0054] 180-Voltage Regulator Module.

[0055] 210 - First inverting operational amplifier module; 220 - Second non-inverting operational amplifier module; 230 - Third inverting operational amplifier module; 240 - Fourth non-inverting operational amplifier module; 250 - Fifth inverting operational amplifier module; 260 - Sixth inverting operational amplifier module; 270 - Seventh inverting operational amplifier module; 280 - Eighth non-inverting operational amplifier module;

[0056] 211 - First operational amplifier; 221 - Second operational amplifier; 231 - Third operational amplifier; 241 - Fourth operational amplifier; 251 - Fifth operational amplifier; 261 - Sixth operational amplifier; 271 - Seventh operational amplifier; 281 - Eighth operational amplifier;

[0057] R1 - First resistor; R1 - Second resistor; R1 - Third resistor; R1 - Fourth resistor; R1 - Fifth resistor; R1 - Sixth resistor; R1 - Seventh resistor; R1 - Eighth resistor; R1 - Ninth resistor; R1 - Tenth resistor; R1 - Eleventh resistor; R1 - Twelfth resistor; R1 - Thirteenth resistor; R1 - Fourteenth resistor; R1 - Fifteenth resistor; D1 - First diode; K1 - Switch module. Detailed Implementation

[0058] The technical solutions of the embodiments of this application will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of this application, and not all embodiments. Based on the embodiments of this application, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of this application.

[0059] In one embodiment, such as Figure 1 As shown, the portable electroanalytical device includes a microfluidic chip 110, a detection circuit 120, a microcontroller module, and a display module 150; the electrodes of the microfluidic chip 110 are connected to the microcontroller module through the detection circuit 120, and the display module 150 is connected to the microcontroller module, wherein:

[0060] Microfluidic chip 110 is used to hold the liquid to be analyzed;

[0061] The detection circuit 120 is used to convert data of the liquid to be analyzed and obtain detection data.

[0062] The microcontroller module is used to carry electrochemical detection software to perform electrical analysis on the detection data;

[0063] The display module 150 is used to enable interaction between the user and the microcontroller module and to display the results.

[0064] Specifically, the detection software is an existing electrochemical detection software, which can be selected from: CH Instruments (CHI) series, Gamry Instruments, MetrohmAutolab, Pine Research Instrumentation, Bio-Logic Science Instruments, QSoas, and LabVIEW.

[0065] Preferably, the CH Instruments (CHI) series is used.

[0066] The portable electroanalytical device provided in this application embodiment can realize the detection of liquids by cyclic voltammetry and chronoamperometry, reducing the size of the electrochemical detection system and providing a brand-new solution for use in small spaces.

[0067] In one possible embodiment, the microcontroller module includes a first microcontroller 131 and a second microcontroller 132; the electrodes of the microfluidic chip 110 are connected to the first microcontroller 131 through a detection circuit 120, and the first microcontroller 131 is connected to the second microcontroller 132.

[0068] The first microcontroller 131 is used to implement data transmission;

[0069] The second microcontroller 132 is used to perform data processing and interact with the display module.

[0070] Specifically, the display module 150 is connected to the second microcontroller 132, and the display module 150 is used to realize the interaction between the user and the second microcontroller 132 and the display of results.

[0071] Specifically, the first microcontroller 131 is an Arduino board;

[0072] Furthermore, the first microcontroller 131 uses an Arduino UNO R3;

[0073] Specifically, the second microcontroller 132 is one of the Latte Panda development board, Raspberry Pi, etc., and serves as a data processor to replace a computer or laptop in processing data and drawing images.

[0074] Preferably, the second microcontroller 132 is a Latte Panda development board, whose Windows 10 system is used to carry electrochemical detection software for easy user operation.

[0075] The detection circuit 120 is implemented via a circuit board, which provides voltage to the electrodes of the microfluidic chip 110 via an electrode adapter, and also acquires and transmits data.

[0076] Optionally, the electrode chip uses ITO glass or FTO glass as the working chip; gold, platinum, or graphite as the counter electrode (CE); and Ag / AgCl, saturated calomel, mercuric oxide, or mercurous sulfate as the reference electrode (RE). It is connected to a chip adapter.

[0077] Specifically, the Latte Panda development board is used to replace a computer to process data and draw images, and finally save experimental data and image results.

[0078] In one embodiment, the portable electrical analyzer also includes a housing 170, in which a battery module 140, a detection circuit 120, and a microcontroller module are fixed, and a microfluidic chip 110 is fixed on the inner wall of the housing 170.

[0079] In one implementation, the portable electrical analyzer also includes a battery module 140, which powers the detection circuit 120 and the microcontroller module.

[0080] Specifically, the battery module 140 is connected to the detection circuit 120 through the voltage regulator module 180 to stabilize the input voltage range of the circuit board and enable the power supply to the detection circuit 120.

[0081] Furthermore, the voltage regulator converts the input 12V into a stable 9V output to the detection circuit 120.

[0082] Specifically, both the battery module 140 and the voltage regulator module 180 are fixed inside the housing 170.

[0083] Specifically, the battery provides power to the circuit board, using lithium batteries. Lithium batteries have advantages such as high energy density, long cycle life, low self-discharge rate, high safety performance, fast charging capability, and environmental friendliness. In addition, they are flexible in form and size, perfectly fitting the 170mm casing.

[0084] Specifically, the microfluidic chip 110 is connected via an adapter, and its housing is made by 3D printing to encapsulate other modules; the display module 150 is placed on the surface of the device housing and can be used to monitor experimental data in real time, control the experimental process, and display the final image.

[0085] In one embodiment, the portable electrical analyzer also includes a cooling fan 160, which is fixed in the housing 170 and powered by the battery module 140. The cooling fan 160 is used to dissipate heat from the detection circuit 120 and the microcontroller module.

[0086] In one possible embodiment, in order to provide a detection circuit 120 for accurately acquiring liquid data, such as Figure 2 The detection circuit 120 includes a first inverting operational amplifier module 210, a second non-inverting operational amplifier module 220, a third inverting operational amplifier module 230, a fourth non-inverting operational amplifier module 240, a fifth inverting operational amplifier module 250, a sixth inverting operational amplifier module 260, a seventh inverting operational amplifier module 270, an eighth non-inverting operational amplifier module 280, a digital-to-analog converter module, an analog-to-digital converter module, and a switching module K1; wherein:

[0087] The first microcontroller 131 is connected to the input terminal of the second non-inverting operational amplifier module 220 through a digital-to-analog converter module. The output terminal of the second non-inverting operational amplifier module 220 is connected to the first input terminal of the third inverting operational amplifier module 230. The first input terminal of the third inverting operational amplifier module 230 is also connected to the first microcontroller 131 module through an analog-to-digital converter module.

[0088] The output of the third inverting operational amplifier module 230 is connected to the first input of the fifth inverting operational amplifier module 250; the second input of the fifth inverting operational amplifier module 250 is connected to the output of the fourth non-inverting operational amplifier module 240; the output of the fifth inverting operational amplifier module 250 is connected to the counter electrode of the microfluidic chip 110 through the switching module K1; the switching module K1 is controlled by the first microcontroller 131.

[0089] The positive input terminal of the fourth in-phase operational amplifier module 240 is connected to the reference electrode of the microfluidic chip 110;

[0090] The second input terminal of the third inverting operational amplifier module 230 is connected to the output terminal of the first inverting operational amplifier module 210, and the input terminal of the first inverting operational amplifier module 210 is connected to the first microcontroller 131; the output terminal of the first inverting operational amplifier module 210 is also connected to the first input terminal of the seventh inverting operational amplifier module 270.

[0091] The second input terminal of the seventh inverting operational amplifier module 270 is connected to the output terminal of the sixth inverting operational amplifier module 260, and the input terminal of the sixth inverting operational amplifier module 260 is connected to the working electrode of the microfluidic chip 110.

[0092] The output of the seventh inverting operational amplifier module 270 is connected to the first microcontroller 131 through an analog-to-digital converter module.

[0093] Furthermore, the output terminal of the seventh inverting operational amplifier module 270 is also connected to the output terminal of the first diode D1, and the input terminal of the first diode D1 is connected to the reference ground.

[0094] Furthermore, the D5 pin of the first microcontroller 131 is connected to one end of the fifteenth resistor R15, the other end of the fifteenth resistor R15 is connected to the positive terminal of the indicator lamp, and the negative terminal of the indicator lamp is connected to the reference ground.

[0095] Specifically, the detection circuit 120 is implemented through a PCB circuit board; the PCB layout is designed and manufactured.

[0096] Specifically, the model number of the analog-to-digital conversion module is ADS1115;

[0097] Specifically, the model of the digital-to-analog converter module is MCP4725;

[0098] Specifically, the input terminal of the first inverting operational amplifier module 210 is connected to the +3V3 pin of the first microcontroller 131.

[0099] Specifically, the first inverting operational amplifier module 210 is an inverting operational amplifier used to create a negative voltage rail symmetrical to the positive reference voltage of 3.3V.

[0100] Specifically, the output of the seventh inverting operational amplifier module 270 is connected to the second input pin AIN1 of the analog-to-digital converter module.

[0101] Specifically, the Arduino board is equipped with an external 12-bit DAC (MCP4725). The constant potential circuit needs to receive the ramp signal, which is generated using the MCP4725 external DAC. The sensor's response is in the form of current, while the Arduino UNO R3 can only process voltage values ​​through an ADC.

[0102] The third inverting operational amplifier module 230 is connected to the first input pin AIN3 of the analog-to-digital converter module;

[0103] Specifically, the analog-to-digital converter module outputs voltage to the detection circuit 120 through AIN1 and AIN3.

[0104] Furthermore, the output terminal Vout of the digital-to-analog converter module is connected to the input terminal of the second in-phase operational amplifier module 220;

[0105] The following are specific embodiments of the first inverting operational amplifier module 210, the second non-inverting operational amplifier module 220, the third inverting operational amplifier module 230, the fourth non-inverting operational amplifier module 240, the fifth inverting operational amplifier module 250, the sixth inverting operational amplifier module 260, the seventh inverting operational amplifier module 270, and the eighth non-inverting operational amplifier module 280.

[0106] Furthermore, the first inverting operational amplifier module 210 includes a first resistor R1, a second resistor R2, and a first operational amplifier 211; wherein:

[0107] One end of the first resistor R1 serves as the input terminal of the first inverting operational amplifier module 210, and the other end of the first resistor R1 is connected to the negative input terminal of the first operational amplifier 211. The negative input terminal of the first operational amplifier 211 is connected to the output terminal of the first operational amplifier 211 through the second resistor R2, and the output terminal of the first operational amplifier 211 is the output terminal of the first inverting operational amplifier module 210.

[0108] Furthermore, this application discloses a circuit structure for a second non-inverting operational amplifier module 220. The fourth non-inverting operational amplifier module 240 is an inverting operational amplifier.

[0109] Furthermore, the second non-inverting operational amplifier module 220 includes a second operational amplifier 221. The positive input terminal of the second operational amplifier 221 serves as the input terminal of the second non-inverting operational amplifier module 220, and the output terminal of the second operational amplifier 221 is connected to the negative input terminal of the second operational amplifier 221. The output terminal of the second operational amplifier 221 serves as the output terminal of the second non-inverting operational amplifier module 220.

[0110] As an exemplary embodiment, the third inverting operational amplifier module 230 includes a third resistor R3, a fourth resistor R4, a fifth resistor R5, a sixth resistor R6, and a third operational amplifier 231; wherein:

[0111] The first input terminal of the third inverting operational amplifier module 230 is connected to one end of the fourth resistor R4, one end of the fourth resistor R4 is connected to one end of the fifth resistor R5, and the other end of the fourth resistor R4 is connected to the other end of the fifth resistor R5; the other end of the fourth resistor R4 is connected to the negative input terminal of the third operational amplifier 231, the positive input terminal of the third operational amplifier 231 is connected to reference ground, and the negative input terminal of the third operational amplifier 231 is connected to the output terminal of the third operational amplifier 231 through the sixth resistor R6.

[0112] The negative input terminal of the third operational amplifier 231 is connected to one end of the third resistor R3, and the other end of the third resistor R3 serves as the second input terminal of the third inverting operational amplifier module 230.

[0113] The output terminal of the third operational amplifier 231 is used as the output terminal of the third operational amplifier 231.

[0114] As an exemplary embodiment, this application discloses a circuit structure for a fourth non-inverting operational amplifier module 240. The fourth non-inverting operational amplifier module 240 is an inverting operational amplifier.

[0115] Furthermore, the fourth non-inverting operational amplifier module 240 includes a fourth operational amplifier 241. The positive input terminal of the fourth operational amplifier 241 serves as the input terminal of the fourth non-inverting operational amplifier module 240, and the output terminal of the fourth operational amplifier 241 is connected to the negative input terminal of the fourth operational amplifier 241. The output terminal of the fourth operational amplifier 241 serves as the output terminal of the fourth non-inverting operational amplifier module 240.

[0116] Furthermore, this application discloses a circuit structure for a fifth inverting operational amplifier module 250, which includes a seventh resistor R7, an eighth resistor R8, and a fifth operational amplifier 251; wherein...

[0117] One end of the eighth resistor R8 serves as the first input terminal of the fifth inverting operational amplifier module 250, and the other end of the eighth resistor R8 is connected to the negative input terminal of the fifth operational amplifier 251. The positive input terminal of the fifth operational amplifier 251 is connected to the reference ground, and the output terminal of the fifth operational amplifier 251 serves as the output terminal of the fifth inverting operational amplifier module 250.

[0118] The negative input terminal of the fifth operational amplifier 251 is also connected to one end of the seventh resistor R7, and the other end of the seventh resistor R7 serves as the second input terminal of the fifth inverting operational amplifier module 250.

[0119] As an exemplary embodiment, a circuit structure for a sixth inverting operational amplifier module 260 is provided. The sixth inverting operational amplifier module 260 includes a fourteenth resistor R14 and a sixth operational amplifier 261. The negative input terminal of the sixth operational amplifier 261 serves as the input terminal of the sixth inverting operational amplifier module 260, and the output terminal of the sixth operational amplifier 261 is connected to the negative input terminal of the sixth operational amplifier 261 through the fourteenth resistor. The output terminal of the sixth operational amplifier 261 serves as the output terminal of the sixth inverting operational amplifier module 260.

[0120] Furthermore, the positive input terminal of the sixth operational amplifier 261 is connected to reference ground.

[0121] As an exemplary embodiment, a circuit structure for a seventh inverting operational amplifier module 270 is provided. The seventh inverting operational amplifier module 270 includes a ninth resistor R9, a tenth resistor R10, an eleventh resistor R11, a twelfth resistor R12, a thirteenth resistor R13, and a seventh operational amplifier 271; wherein:

[0122] The first input terminal of the seventh inverting operational amplifier module 270 is connected to the negative input terminal of the seventh operational amplifier 271 through the ninth resistor R9. The negative input terminal of the seventh operational amplifier 271 is also connected to the second input terminal of the seventh inverting operational amplifier module 270 through the tenth resistor R10. The negative input terminal of the seventh operational amplifier 271 is also connected to the second input terminal of the seventh inverting operational amplifier module 270 through the eleventh resistor R11.

[0123] The negative input terminal of the seventh operational amplifier 271 is also connected to the output terminal of the seventh operational amplifier 271 through the twelfth resistor R12; the negative input terminal of the seventh operational amplifier 271 is also connected to the output terminal of the seventh operational amplifier 271 through the thirteenth resistor R13.

[0124] The positive input terminal of the seventh operational amplifier 271 is connected to the reference ground; the output terminal of the seventh operational amplifier 271 is the output terminal of the seventh inverting operational amplifier module 270.

[0125] As an exemplary embodiment, a circuit structure of an eighth non-inverting operational amplifier module 280 is provided. The eighth non-inverting operational amplifier module 280 includes an eighth operational amplifier 281. The positive input terminal of the eighth operational amplifier 281 serves as the input terminal of the eighth non-inverting operational amplifier module 280. The output terminal of the eighth operational amplifier 281 is connected to the negative input terminal of the eighth operational amplifier 281, and the output terminal of the eighth operational amplifier 281 serves as the output terminal of the eighth non-inverting operational amplifier module 280.

[0126] Specifically, in this embodiment of the application, the input signal obtained by the detection circuit 120 has almost no current buffer.

[0127] Specifically, the sixth inverting operational amplifier module 260 is a current-to-voltage converter. By connecting its non-inverting input to the circuit ground, the leads of the operating electrodes will remain in virtual ground. According to Ohm's law, the potential of the sixth inverting operational amplifier module 260 must be adjusted to Eout. F =-I*R14, to shunt any current on R14. Then input this potential to the sixth inverting operational amplifier module 260.

[0128] The Arduino comes with an external 12-bit digital-to-analog converter (MCP4725). The detection circuit 120 needs to receive a ramp signal, which is generated by the digital-to-analog converter. The response of the analog-to-digital converter and the digital-to-analog converter is in the form of current, while the Arduino UNO R3 needs to process the voltage value through the analog converter.

[0129] During use, the lithium battery is charged at the reserved charging port to ensure sufficient power for normal operation of the device. After charging is complete, turn on the detection circuit 120 switch and the Latte Panda development board switch to prepare for testing. Before testing, add the sample solution to the microfluidic chip 110 as shown in the figure, ensuring that it covers the 5mm × 5mm electrode area and the three electrodes.

[0130] Open the software on the Latte Panda development board using the touchscreen display module 150 to start the experiment.

[0131] First, confirm the port name. You can find the port name of the Arduino board's USB port in the Device Manager of the Windows 10 system (serial port 5 in the following example). After confirmation, open the downloaded software platform and click "Run" to bring up the software interface. In the software interface, you must first complete the serial port test. Select the port and click the "Serial Communication" button. After a short wait, a prompt will appear indicating that the test is complete.

[0132] After confirming everything is correct, select either cyclic voltammetry or chronoamperometry for detection. Once opened, locate the corresponding port and set the parameters. After setting the parameters, upload them; the circuit board receives the parameters transmitted from the Arduino. After clicking "Run," the file will be saved. After saving, the oxidation-reduction reaction begins on the electrodes, and the obtained current and other data are transmitted back to the development board via the Arduino board, where they are displayed as images in the software.

[0133] The following are specific embodiments of electrical analysis performed using the portable electrical analysis device provided in this application:

[0134] Example 1:

[0135] This embodiment provides a solution sample, which is prepared by mixing a 1 mmol / L potassium ferricyanide solution and a 1 mmol / L potassium ferrocyanide solution with a potassium chloride solution. The working electrode of the microfluidic chip 110 is made of ITO glass, Ag / AgCl is used as the reference electrode, and gold is used as the auxiliary electrode.

[0136] Turn on the entire device and use the touchscreen function of the display module 150 to open the accompanying software installed on the Latte Panda development board. Select serial port 5 for serial communication testing, and after the test is completed, start the cyclic voltammetry test.

[0137] Still select serial port 5, set the parameters, connect it to the counter electrode via switch module K1, select the output voltage linear range of the digital-to-analog converter module as -0.2V to 0.6V, the scan speed as 100mV / s, and cycle twice. After setting, start serial communication. After communication is complete, transfer the parameter settings through the Arduino board, save the file, and start the experiment.

[0138] After startup, the device applies a voltage to the working electrode, causing a redox reaction of the sample solution on the electrode surface. The output current data is transmitted to the Panda development board via the Arduino board, and the obtained image is displayed on the display module 150. It was observed that the linear range conforms to the set parameter range, and the image has obvious oxidation and reduction peaks, such as... Figure 3 As shown.

[0139] Example 2:

[0140] The sample solution and electrode selection in this embodiment are the same as in Example 1.

[0141] This embodiment repeats some content from Embodiment 1, the difference being that the timing current method detection is enabled after the test. The parameters are set to -0.5V duration for 10s and +0.5V duration for 10s. Serial communication is then initiated. After communication is complete, the parameter settings are transmitted via the Arduino board, the file is saved, and the experiment begins. At the start of the experiment, the circuit board provides a stable potential, and a decreasing current trend is observed. The results are as follows... Figure 4 As shown.

[0142] Example 3:

[0143] This embodiment provides a solution sample, which is ruthenium tripyridine, prepared from 0.1 mol / L PBS buffer to 5 mmol / L ruthenium tripyridine, with TPrA as a co-reactant, and the electrode of the microfluidic chip 110 is still the electrode in Example 1.

[0144] As in Example 1, turn on the entire device and open the accompanying software installed on the Latte Panda development board via the touchscreen function of the display module 150. Select serial port 5 for serial communication testing. After the test is completed, start the cyclic voltammetry test. Again, select serial port 5, set the parameters, change the voltage linear region to 0 to 1.6V, the scan speed to 100mV / s, and cycle twice. After setting, start serial communication. After communication is complete, transmit the parameter settings through the Arduino board, save the file, and start the experiment. After starting, the device applies voltage to the working electrode, causing the sample solution to undergo a redox reaction on the electrode surface. The output current data is transmitted to the development board through the Arduino board, and the obtained image is displayed on the display module 150. The test results are as follows. Figure 5 As shown.

[0145] The portable electrical analysis device provided in this application has the following technical advantages:

[0146] The battery provides power to the circuit board. It uses lithium batteries, which have advantages such as high energy density, long cycle life, low self-discharge rate, high safety performance, fast charging capability, and environmental friendliness.

[0147] The display module 150 is a touch screen display module 150, which can control the experimental process through touch screen. The display module 150 is connected to the Latte Panda development board and plays the role of controlling the Latte Panda development board. In addition, experimental data and images will also be displayed on the display module 150. The display module 150 is powered by the Latte Panda development board.

[0148] This application eliminates the need for a computer, using a Latte Panda development board and a touchscreen display to control the electrochemical detection circuitry. This replaces the computer, significantly reducing the space occupied by the device and making it more suitable for use in confined spaces.

[0149] In summary, the electrochemical detection device provided in this application can perform cyclic voltammetry and chronoamperometry detection of solutions. It has a simple structure and small size, and electrochemical detection can be completed simply by operating the display screen, thus saving space costs.

[0150] Based on the same inventive concept, this application also provides an application scenario that enables electrochemical detection such as cyclic voltammetry and chronoamperometry using the aforementioned portable electroanalytical device. Its inventive concept and technical effects are similar and will not be elaborated upon here.

[0151] The technical features of the above embodiments can be combined in any way. For the sake of brevity, not all possible combinations of the technical features in the above embodiments are described. However, as long as there is no contradiction in the combination of these technical features, they should be considered to be within the scope of this specification.

[0152] This document uses specific examples to illustrate the principles and implementation methods of this application. The descriptions of the above embodiments are only for the purpose of helping to understand the methods and core ideas of this application. At the same time, for those skilled in the art, there will be changes in the specific implementation methods and application scope based on the ideas of this application. In summary, the content of this specification should not be construed as a limitation of this application.

Claims

1. A portable electroanalytical device, characterized in that, The portable electroanalytical device includes a microfluidic chip, a detection circuit, a microcontroller module, and a display module; the electrodes of the microfluidic chip are connected to the microcontroller module through the detection circuit, and the display module is connected to the microcontroller module, wherein: The microfluidic chip is used to hold the liquid to be analyzed; The detection circuit is used to convert data from the liquid to be analyzed to obtain detection data; The microcontroller module is used to carry electrochemical detection software to perform electrochemical analysis on the detection data; The display module is used to enable interaction between the user and the microcontroller module and to display the results. The microcontroller module includes a first microcontroller and a second microcontroller; the electrodes of the microfluidic chip are connected to the first microcontroller through the detection circuit, and the first microcontroller is connected to the second microcontroller. The first microcontroller is used to implement data transmission; The second microcontroller is used to perform data processing and interact with the display module.

2. The portable electroanalytical device according to claim 1, characterized in that, The detection circuit includes a first inverting operational amplifier module, a second non-inverting operational amplifier module, a third inverting operational amplifier module, a fourth non-inverting operational amplifier module, a fifth inverting operational amplifier module, a sixth inverting operational amplifier module, a seventh inverting operational amplifier module, an eighth non-inverting operational amplifier module, a digital-to-analog converter module, an analog-to-digital converter module, and a switching module; wherein: The first microcontroller is connected to the input terminal of the second non-inverting operational amplifier module through the digital-to-analog converter module, the output terminal of the second non-inverting operational amplifier module is connected to the first input terminal of the third inverting operational amplifier module, and the first input terminal of the third inverting operational amplifier module is also connected to the first microcontroller through the analog-to-digital converter module; The output terminal of the third inverting operational amplifier module is connected to the first input terminal of the fifth inverting operational amplifier module; the second input terminal of the fifth inverting operational amplifier module is connected to the output terminal of the fourth non-inverting operational amplifier module; the output terminal of the fifth inverting operational amplifier module is connected to the counter electrode of the microfluidic chip through the switching module; the switching module implements switching control through the first microcontroller. The positive input terminal of the fourth in-phase operational amplifier module is connected to the reference electrode of the microfluidic chip; The second input terminal of the third inverting operational amplifier module is connected to the output terminal of the first inverting operational amplifier module, and the input terminal of the first inverting operational amplifier module is connected to the first microcontroller; the output terminal of the first inverting operational amplifier module is also connected to the first input terminal of the seventh inverting operational amplifier module. The second input terminal of the seventh inverting operational amplifier module is connected to the output terminal of the sixth inverting operational amplifier module, and the input terminal of the sixth inverting operational amplifier module is connected to the working electrode of the microfluidic chip. The output of the eighth in-phase operational amplifier module is connected to the first microcontroller through the analog-to-digital converter module.

3. The portable electroanalytical device according to claim 2, characterized in that, The third inverting operational amplifier module includes a third resistor, a fourth resistor, a fifth resistor, a sixth resistor, and a third operational amplifier; wherein: The first input terminal of the third inverting operational amplifier module is connected to one end of the fourth resistor, one end of the fourth resistor is connected to one end of the fifth resistor, and the other end of the fourth resistor is connected to the other end of the fifth resistor; the other end of the fourth resistor is connected to the negative input terminal of the third operational amplifier, the positive input terminal of the third operational amplifier is connected to reference ground, and the negative input terminal of the third operational amplifier is connected to the output terminal of the third operational amplifier through the sixth resistor. The negative input terminal of the third operational amplifier is connected to one end of the third resistor, and the other end of the third resistor serves as the second input terminal of the third inverting operational amplifier module. The output terminal of the third operational amplifier is used as the output terminal of the third operational amplifier.

4. The portable electroanalytical device according to claim 2, characterized in that, The fifth inverting operational amplifier module includes a seventh resistor, an eighth resistor, and a fifth operational amplifier; wherein... One end of the eighth resistor serves as the first input terminal of the fifth inverting operational amplifier module, the other end of the eighth resistor is connected to the negative input terminal of the fifth operational amplifier, the positive input terminal of the fifth operational amplifier is connected to reference ground, and the output terminal of the fifth operational amplifier serves as the output terminal of the fifth inverting operational amplifier module. The negative input terminal of the fifth operational amplifier is also connected to one end of the seventh resistor, and the other end of the seventh resistor serves as the second input terminal of the fifth inverting operational amplifier module.

5. The portable electroanalytical device according to claim 2, characterized in that, The seventh inverting operational amplifier module includes a ninth resistor, a tenth resistor, an eleventh resistor, a twelfth resistor, a thirteenth resistor, and a seventh operational amplifier; wherein: The first input terminal of the seventh inverting operational amplifier module is connected to the negative input terminal of the seventh operational amplifier through the ninth resistor. The negative input terminal of the seventh operational amplifier is also connected to the second input terminal of the seventh inverting operational amplifier module through the tenth resistor. The negative input terminal of the seventh operational amplifier is also connected to the second input terminal of the seventh inverting operational amplifier module through the eleventh resistor. The negative input terminal of the seventh operational amplifier is also connected to the output terminal of the seventh operational amplifier through the twelfth resistor; the negative input terminal of the seventh operational amplifier is also connected to the output terminal of the seventh operational amplifier through the thirteenth resistor. The positive input terminal of the seventh operational amplifier is connected to the reference ground; the output terminal of the seventh operational amplifier is the output terminal of the seventh inverting operational amplifier module.

6. The portable electroanalytical device according to any one of claims 1-5, characterized in that, The portable electrical analyzer also includes a battery module and a voltage regulator module. The battery module is used to power the detection circuit and the microcontroller module, and the battery module is connected to the detection circuit through the voltage regulator module.

7. The portable electroanalytical device according to claim 6, characterized in that, The portable electrical analyzer also includes a housing, in which the battery module, the detection circuit, and the microcontroller module are all fixed, and the microfluidic chip is fixed on the outer wall of the housing.

8. The portable electroanalytical device according to claim 7, characterized in that, The portable electrical analyzer also includes a cooling fan, which is fixed in the housing and powered by the battery module. The cooling fan is used to dissipate heat from the detection circuit and the microcontroller module.

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